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MRI parameters consisted of DWI, , and \u2010weighted fast spoiled gradient echo before and after contrast. The post\u2010MRg\u2010HIFUS treatment volume in the fibroid was assessed by and DWI. Trace apparent diffusion coefficient maps were constructed for quantitative analysis. The regions of the treated uterine tissue were defined by a semisupervised segmentation method called the \u201ceigenimage filter,\u201d using both and DWI. Signal\u2010to\u2010noise ratios were determined for the pretreatment images. Segmented regions were tested by a similarity index for congruence. Descriptive, regression, and Bland\u2013Altman statistics were calculated.<\/jats:p><\/jats:sec>Results<\/jats:title>: All the patients exhibited heterogeneously increased DWI signal intensity localized in the treated fibroid regions and were colocalized with the defined area. The mean pretreatment signal intensity ratios were and . The congruence between the regions was significant, with a similarity of 84% and a difference of 8% between the regions. Regression analyses of the and DWI segmented treatment volumes were found to be significantly correlated with the linear equation, . There is good agreement between the regions defined by cT1WI and DWI in most of the cases as shown from the Bland\u2013Altman plots.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>: Diffusion\u2010weighted imaging exhibited excellent agreement, congruence, and correlation with the\u2010defined region of treatment in uterine fibroid. Therefore, DWI could be useful as an adjunct for assessing treatment of uterine fibroids by MRg\u2010HIFUS.<\/jats:p><\/jats:sec>","DOI":"10.1118\/1.3475940","type":"journal-article","created":{"date-parts":[[2010,8,31]],"date-time":"2010-08-31T22:55:42Z","timestamp":1283295342000},"page":"4768-4776","source":"Crossref","is-referenced-by-count":17,"title":["Comparison between diffusion\u2010weighted imaging, \u2010weighted, and postcontrast \u2010weighted imaging after MR\u2010guided, high intensity, focused ultrasound treatment of uterine leiomyomata: Preliminary results"],"prefix":"10.1002","volume":"37","author":[{"given":"Michael A.","family":"Jacobs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H.","family":"Gultekin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun S.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,8,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/94.4.435"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.09.010"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.07.1298"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199404000-00013"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199404000-00012"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)40479-4"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1994.tb21775.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92282-2"},{"key":"e_1_2_7_10_1","first-page":"1754","article-title":"Arterial embolization\u2014new treatment for menorrhagia due to uterine fibromas","volume":"24","author":"Ravina J. 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