{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:32:38Z","timestamp":1791300758909,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T00:00:00Z","timestamp":1294704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["312136\u201006"],"award-info":[{"award-number":["312136\u201006"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["323405\u201006"],"award-info":[{"award-number":["323405\u201006"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["CPG\u201080085"],"award-info":[{"award-number":["CPG\u201080085"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:sec><jats:title>Purpose:<\/jats:title><jats:p>Atherosclerosis of peripheral cerebral arteries can lead to stroke either by stenosis formation or plaque rupture. This pathology is initiated by the alteration of arterial wall mechanical properties shown to be assessable by ultrasound elastography. Recently, noninvasive vascular elastography (NIVE) was introduced for noninvasive imaging of the mechanical properties of superficial arteries as markers of vulnerable plaques. However, NIVE motion estimates are angle\u2010dependent, with optimal scanning angle being represented by the alignment of tissue motion with ultrasound beam orientation. The objective of this study was to introduce a model that compensates for such angle\u2010dependence in order to reduce the bias on strain estimates, namely, when investigating longitudinal vessel segments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>The model is based on the Lagrangian speckle model estimator (LSME) because the LSME assesses the 2D\u2010deformation matrix required to compute the scanning angle.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Experiments on vessel\u2010mimicking phantoms indicated that such a model enables the estimation of scanning angle with less than 3\u2010degrees error. The method was also validated<jats:italic>in vivo<\/jats:italic> in human carotid arteries where less than 4\u2010degrees error was observed. In both cases, the compensative model estimated the inclination angles with low variability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Angle\u2010dependence may be an important factor to consider in avoiding potentially distort clinical diagnoses. Results, reported in this article, suggest that the LSME\u2010based compensative model might be considered as a very interesting and promising clinical tool for NIVE applications.<\/jats:p><\/jats:sec>","DOI":"10.1118\/1.3539701","type":"journal-article","created":{"date-parts":[[2011,2,2]],"date-time":"2011-02-02T23:28:13Z","timestamp":1296689293000},"page":"727-735","source":"Crossref","is-referenced-by-count":9,"title":["A compensative model for the angle\u2010dependence of motion estimates in noninvasive vascular elastography"],"prefix":"10.1002","volume":"38","author":[{"given":"Elizabeth","family":"Mercure","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Deprez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00e9mie","family":"Fromageau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Basset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Soulez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Cloutier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roch L.","family":"Maurice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301\u20105629(02)00645\u20102"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301\u20105629(03)00904\u20109"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000078633.31922.8A"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2004.04.003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2003.823066"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2007.05.020"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2006.09.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/53\/22\/008"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.2948320"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2004.07.022"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2006.07.014"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1109\/TUFFC.2004.1308687"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2008.2011510"},{"key":"e_1_2_7_15_1","series-title":"IEEE Ultrasonics Symposium","first-page":"859","author":"Bertrand M.","year":"1989"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000185679.62634.0a"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000206440.48756.f7"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2004.tb00248.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1109\/TUFFC.2007.273"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.376133"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.2936771"},{"key":"e_1_2_7_22_1","first-page":"1","article-title":"A pulsed Doppler ultrasonic system for making noninvasive measurements of the mechanical properties of soft tissue","volume":"24","author":"Krouskop T. 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