{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T14:39:27Z","timestamp":1773671967746,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T00:00:00Z","timestamp":1445299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aip.org"],"crossmark-restriction":true},"short-container-title":["Medical Physics"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:sec><jats:title>Purpose:<\/jats:title><jats:p>To present a novel brachytherapy technique, called multihelix rotating shield brachytherapy (H\u2010RSBT), for the precise angular and linear positioning of a partial shield in a curved applicator. H\u2010RSBT mechanically enables the dose delivery using only linear translational motion of the radiation source\/shield combination. The previously proposed approach of serial rotating shield brachytherapy (S\u2010RSBT), in which the partial shield is rotated to several angular positions at each source dwell position [W. Yang <jats:italic>et al.<\/jats:italic>, \u201cRotating\u2010shield brachytherapy for cervical cancer,\u201d Phys. Med. Biol. <jats:bold>58<\/jats:bold>, 3931\u20133941 (2013)], is mechanically challenging to implement in a curved applicator, and H\u2010RSBT is proposed as a feasible solution.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>A Henschke\u2010type applicator, designed for an electronic brachytherapy source (Xoft Axxent\u2122) and a 0.5 mm thick tungsten partial shield with 180\u00b0 or 45\u00b0 azimuthal emission angles and 116\u00b0 asymmetric zenith angle, is proposed. The interior wall of the applicator contains six evenly spaced helical keyways that rigidly define the emission direction of the partial radiation shield as a function of depth in the applicator. The shield contains three uniformly distributed protruding keys on its exterior wall and is attached to the source such that it rotates freely, thus longitudinal translational motion of the source is transferred to rotational motion of the shield. S\u2010RSBT and H\u2010RSBT treatment plans with 180\u00b0 and 45\u00b0 azimuthal emission angles were generated for five cervical cancer patients with a diverse range of high\u2010risk target volume (HR\u2010CTV) shapes and applicator positions. For each patient, the total number of emission angles was held nearly constant for S\u2010RSBT and H\u2010RSBT by using dwell positions separated by 5 and 1.7 mm, respectively, and emission directions separated by 22.5\u00b0 and 60\u00b0, respectively. Treatment delivery time and tumor coverage (<jats:italic>D<\/jats:italic><jats:sub>90<\/jats:sub> of HR\u2010CTV) were the two metrics used as the basis for evaluation and comparison. For all the generated treatment plans, the <jats:italic>D<\/jats:italic><jats:sub>90<\/jats:sub> of the HR\u2010CTV in units of equivalent dose in 2 Gy fractions (EQD2) was escalated until the <jats:italic>D<\/jats:italic><jats:sub>2cc<\/jats:sub> (minimum dose to hottest 2 cm<jats:sup>3<\/jats:sup>) tolerance of either the bladder (90 Gy<jats:sub>3<\/jats:sub>), rectum (75 Gy<jats:sub>3<\/jats:sub>), or sigmoid colon (75 Gy<jats:sub>3<\/jats:sub>) was reached.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Treatment time changed for H\u2010RSBT versus S\u2010RSBT by \u22127.62% to 1.17% with an average change of \u22122.8%, thus H\u2010RSBT treatments times tended to be shorter than for S\u2010RSBT. The HR\u2010CTV <jats:italic>D<\/jats:italic><jats:sub>90<\/jats:sub> also changed by \u22122.7% to 2.38% with an average of \u22120.65%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p>H\u2010RSBT is a mechanically feasible delivery technique for use in the curved applicators needed for cervical cancer brachytherapy. S\u2010RSBT and H\u2010RSBT were clinically equivalent for all patients considered, with the H\u2010RSBT technique tending to require less time for delivery.<\/jats:p><\/jats:sec>","DOI":"10.1118\/1.4933244","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T20:49:03Z","timestamp":1445374143000},"page":"6579-6588","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":20,"title":["Multihelix rotating shield brachytherapy for cervical cancer"],"prefix":"10.1002","volume":"42","author":[{"given":"Hossein","family":"Dadkhah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan T.","family":"Flynn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2011.07.012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2005.11.014"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.04.041"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.01.036"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4897617"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/58\/11\/3931"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4802750"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4828778"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2014.02.039"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1586\/17434440.6.1.27"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1201\/b13224-9"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2004.12.015"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.597458"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.2357021"},{"key":"e_1_2_7_16_1","volume-title":"A Dosimetric Characterization of an Electronic Brachytherapy Source in Terms of Absorbed Dose to Water","author":"Pike T. L.","year":"2012"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031\u20109155\/45\/1\/306"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.10.033"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2009.07.001"}],"container-title":["Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1118%2F1.4933244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1118%2F1.4933244","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1118\/1.4933244","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1118\/1.4933244","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/pdf\/10.1118\/1.4933244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T10:10:05Z","timestamp":1694340605000},"score":1,"resource":{"primary":{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/10.1118\/1.4933244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,20]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1118\/1.4933244"],"URL":"https:\/\/doi.org\/10.1118\/1.4933244","archive":["Portico"],"relation":{},"ISSN":["0094-2405","2473-4209"],"issn-type":[{"value":"0094-2405","type":"print"},{"value":"2473-4209","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,20]]}}}