{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:34:21Z","timestamp":1761863661300},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T00:00:00Z","timestamp":1352332800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>The purpose of this study was to investigate the potential benefits of using triple\u2010arc volumetric\u2010intensity modulated arc radiotherapy (RapidArc (RA)) for the treatment of early\u2010stage nasopharyngeal carcinoma (NPC). A comprehensive evaluation was performed including plan quality, integral doses, and peripheral doses. Twenty cases of stage I or II NPC were selected for this study. Nine\u2010field sliding window IMRT, double\u2010arc, and triple\u2010arc RA treatment plans were compared with respect to target coverage, dose conformity, critical organ sparing, and integral doses. Measurement of peripheral doses was performed using thermoluminescent dosimeters in an anthropomorphic phantom. While similar conformity and target coverage were achieved by the three types of plans, triple\u2010arc RA produced better sparing of parotid glands and spinal cord than double\u2010arc RA or IMRT. Double\u2010arc RA plans produced slightly inferior parotid sparing and dose homogeneity than the other two delivery methods. The monitor units (MU) required for triple\u2010arc were about 50% less than those of IMRT plans, while there was no significant difference in the required MUs between triple\u2010arc and double\u2010arc RA plans. The peripheral dose in triple\u2010arc RA was found to be 50% less compared to IMRT near abdominal and pelvic region. Triple\u2010arc RA improves both the plan quality and treatment efficiency compared with IMRT for the treatment of early stage NPC. It has become the preferred choice of treatment delivery method for early stage NPC at our center.<\/jats:p><jats:p>PACS numbers: 87.53.Bn, 87.55.D, 87.55.de, 87.55.dk, 87.56.ng<\/jats:p>","DOI":"10.1120\/jacmp.v13i6.3887","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T22:54:59Z","timestamp":1488236099000},"page":"189-202","source":"Crossref","is-referenced-by-count":11,"title":["A comprehensive dosimetric evaluation of using RapidArc volumetric\u2010modulated arc therapy for the treatment of early\u2010stage nasopharyngeal carcinoma"],"prefix":"10.1002","volume":"13","author":[{"given":"Monica W.K.","family":"Kan","sequence":"first","affiliation":[{"name":"Department of Oncology Princess Margaret Hospital  Hong Kong SAR"},{"name":"Department of Physics and Materials Science City University of Hong Kong  Hong Kong 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