{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T09:31:49Z","timestamp":1772011909916,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T00:00:00Z","timestamp":1394064000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p>This study compares the dosimetry of high\u2010dose\u2010rate intracavitary brachytherapy (HDR\u2010ICBT) performed with and without general anesthesia\/spinal anesthesia (GA\/SA) in patients with cervical carcinoma. We retrospectively retrieved the records of 138 HDR\u2010ICBT applicator insertions performed in 46 patients: 69 performed with GA\/SA (anesthesia group known as AG) in 23 patients, and 69 performed without GA\/SA (nonanesthesia group known as NAG) in 23 patients. The intracavitary brachytherapy (ICBT) application was done with central tandem and two vaginal ovoids. For each ICBT plan, a high\u2010dose\u2010rate (HDR) dose of 7 Gy was prescribed to point A. From each plan, the doses to Point B right <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0001.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0001\"\/>, Point B left <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0002.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0002\"\/>, bladder and rectal reference points (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0003.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0003\"\/> and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0004.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0004\"\/>) were recorded and compared in the two groups. Student's t\u2010test was applied to find out the significance of difference. The two groups were comparable in terms of demography and clinical characteristics. Mean Point <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0005.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0005\"\/> doses in AG and NAG were 1.89 Gy (27% of Point A dose) and 1.82 Gy (26% of Point A dose), respectively. Mean Point <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0006.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0006\"\/> doses in AG and NAG were 1.91 Gy (27% of Point A dose) and 1.85 Gy (26% of point A), respectively (p\u2010value 0.7). The mean dose to <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0007.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0007\"\/> in AG and NAG was 5.03 Gy and 4.90 Gy, respectively (p\u2010value 0.6). The mean dose to <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20060-math-0008.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20060:acm20060-math-0008\"\/> was significantly higher in AG than NAG (5.09 Gy vs. 4.49 Gy, p\u2010value 0.01). Although based on conventional 2D dosimetry planning, our study has demonstrated that avoiding GA\/SA does not result in inferior HDR\u2010ICBT dosimetry.<\/jats:p><jats:p>PACS number: 87.53.Jw, 87.50.cm<\/jats:p>","DOI":"10.1120\/jacmp.v15i2.4670","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T23:25:53Z","timestamp":1488237953000},"page":"60-66","source":"Crossref","is-referenced-by-count":10,"title":["Comparison of high\u2010dose\u2010rate intracavitary brachytherapy dosimetry with and without anesthesia in patients with cervical carcinoma"],"prefix":"10.1002","volume":"15","author":[{"given":"Daya N.","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pritee","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seema","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leena","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pandjatcharam","family":"Jagadesan","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology All India Institute of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goura K.","family":"Rath","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology All India Institute of Medical Sciences  New Delhi 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