{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:17:13Z","timestamp":1762507033448},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T00:00:00Z","timestamp":1410134400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:p>The purpose of the present study was to compare the impact of pulmonary function, body habitus, and stereotactic body radiation therapy (SBRT) immobilization on setup and reproducibility for upper lung tumor. From 2008 through 2011, our institution's prospective SBRT database was searched for patients with upper lung tumors. Two SBRT immobilization strategies were used: full\u2010length BodyFIX and thermoplastic S\u2010frame. At simulation, free\u2010breathing, four\u2010dimensional computed tomography was performed. For each treatment, patients were set up to isocenter with in\u2010room lasers and skin tattoos. Shifts from initial and subsequent couch positions with cone\u2010beam computed tomography (CBCT) were analyzed. Accounting for setup uncertainties, institutional tolerance of CBCT\u2010based shifts for treatment was 2, 2, and 4 mm in left\u2013right, anterior\u2013posterior, and cranial\u2013caudal directions, respectively; shifts exceeding these limits required reimaging. Each patient's pretreatment pulmonary function test was recorded. A multistep, multivariate linear regression model was performed to elucidate intervariable dependency for three\u2010dimensional calculated couch shift parameters. BodyFIX was applied to 76 tumors and S\u2010frame to 17 tumors. Of these tumors, 41 were non\u2013small cell lung cancer and 15 were metastatic from other sites. Lesions measured <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20235-math-0001.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20235:acm20235-math-0001\" \/>, 1.1 to 2 (50%), 2.1 to 3 (25%), and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20235-math-0002.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20235:acm20235-math-0002\" \/> cm. Errors from first shifts of first fractions were significantly less with S\u2010frame than BodyFIX (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20235-math-0003.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20235:acm20235-math-0003\" \/>). No difference in local control (LC) was found between S\u2010frame and BodyFIX (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20235-math-0004.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20235:acm20235-math-0004\" \/>); two\u2010year LC rate was 94%. Multivariate modeling confirmed that the ratio of forced expiratory volume in the first second of expiration to forced vital capacity, body habitus, and the immobilization device significantly impacted couch shift errors. For upper lung tumors, initial setup was more consistent with S\u2010frame than BodyFIX, resulting in fewer CBCT scans. Patients with obese habitus and poor lung function had more SBRT setup uncertainty; however, outcome and probability for LC remained excellent.<\/jats:p><jats:p>PACS number: 89.20.\u2010a<\/jats:p>","DOI":"10.1120\/jacmp.v15i5.4931","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T23:39:09Z","timestamp":1488238749000},"page":"235-245","source":"Crossref","is-referenced-by-count":8,"title":["Influence of patient's physiologic factors and immobilization choice with stereotactic body radiotherapy for upper lung tumors"],"prefix":"10.1002","volume":"15","author":[{"given":"Terence T.","family":"Sio","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew R.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis E. Fong","family":"de los Santos","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Hallemeier","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan R.","family":"Foster","sequence":"additional","affiliation":[{"name":"Division of Biomedical Statistics and Informatics Mayo Clinic  Rochester MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean S.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather J.","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda I.","family":"Garces","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth R.","family":"Olivier","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Rochester MN"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,9,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.261"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2011.04.021"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-1-30"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.02.060"},{"issue":"1","key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"eS26","DOI":"10.3949\/ccjm.79.s2.06","article-title":"Stereotactic body radiotherapy for stage I non\u2010small cell lung cancer","volume":"79","author":"Stephans K","year":"2012","journal-title":"Cleve Clin J Med."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603106"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2010.01.025"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2011.04.002"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.05.034"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-4-15"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.08.004"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.09.048"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01516-4"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.12.091"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.12.022"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01621-2"},{"issue":"1","key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"eS17","DOI":"10.3949\/ccjm.79.s2.04","article-title":"Preoperative evaluation of the lung resection candidate","volume":"79","author":"Mazzone P","year":"2012","journal-title":"Cleve Clin J Med."},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181a99ff6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-0207"}],"container-title":["Journal of Applied Clinical Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1120%2Fjacmp.v15i5.4931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1120%2Fjacmp.v15i5.4931","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/pdf\/10.1120\/jacmp.v15i5.4931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T20:34:14Z","timestamp":1696538054000},"score":1,"resource":{"primary":{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/10.1120\/jacmp.v15i5.4931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1120\/jacmp.v15i5.4931"],"URL":"https:\/\/doi.org\/10.1120\/jacmp.v15i5.4931","archive":["Portico"],"relation":{},"ISSN":["1526-9914","1526-9914"],"issn-type":[{"value":"1526-9914","type":"print"},{"value":"1526-9914","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9]]}}}