{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T11:20:18Z","timestamp":1696677618649},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,5,25]],"date-time":"2006-05-25T00:00:00Z","timestamp":1148515200000},"content-version":"vor","delay-in-days":85,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p>The purpose of this study is to determine the extracranial dose in patients treated for pituitary adenoma with conventional and stereotactic radiotherapy (SRT). Twelve patients receiving treatment with radiation for pituitary adenoma were selected. Six patients underwent SRT, and six patients underwent conventional radiotherapy. Extracranial doses were measured with pre\u2010irradiation annealed lithium fluoride thermoluminscent dosimetry (TLD) chips. The chips were wrapped and placed on the patients\u2019 skin, over each eyelid, the thyroid, chest, and scrotum for males and over the suprapubic region for females. Postradiation annealing was done, and the TLDs were read in a TLD reader system. The results were analyzed using the Wilcoxon matched\u2010pairs signed rank test by SPSS, version 6.01. The doses to the thyroid, center, and gonads were significantly higher (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0001.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0001\" \/>, <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0002.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0002\" \/>, and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0003.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0003\" \/>, respectively) in patients receiving SRT than in conventional radiotherapy portals (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0004.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0004\" \/>, <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0005.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0005\" \/>, and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0006.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0006\" \/>). But the average doses to the right eye (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0007.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0007\" \/>) and to the left eye (<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0008.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0008\" \/>) in the stereotactic group were less when compared with the patients treated with conventional radiotherapy, who received <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0009.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0009\" \/> and <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/acm20096-math-0010.png\" xlink:title=\"urn:x-wiley:15269914:media:acm20096:acm20096-math-0010\" \/>, respectively. In conclusion, SRT is definitely superior to conventional radiotherapy as far as dose to the surrounding normal structures is concerned. The higher extracranial doses in SRT seem to be within the acceptable range; however, the clinical significance of this is still unclear and needs longer followup.<\/jats:p><jats:p>PACS number: 87.53.Ly<\/jats:p>","DOI":"10.1120\/jacmp.v7i2.2203","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T22:13:00Z","timestamp":1172182380000},"page":"96-100","source":"Crossref","is-referenced-by-count":0,"title":["Extracranial doses in stereotactic and conventional radiotherapy for pituitary adenomas"],"prefix":"10.1002","volume":"7","author":[{"given":"Thomas Samuel","family":"Ram","sequence":"first","affiliation":[{"name":"Christian Medical College Department of Radiation Oncology  Vellore 632 004 India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul B.","family":"Ravindran","sequence":"additional","affiliation":[{"name":"Christian Medical College Department of Radiation Oncology  Vellore 632 004 India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faith R.","family":"Viswanathan","sequence":"additional","affiliation":[{"name":"Christian Medical College Department of Radiation Oncology  Vellore 632 004 India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Perungulam Narayan","family":"Viswanathan","sequence":"additional","affiliation":[{"name":"Christian Medical College Department of Radiation Oncology  Vellore 632 004 India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon P.","family":"Pavamani","sequence":"additional","affiliation":[{"name":"Christian Medical College Department of Radiation Oncology  Vellore 632 004 India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,5,25]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"JW Kernohan GP Sayre PW Grisby CA Perez LW Brady 1956 Armed Forces Institute of Pathology Washington DC 7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00410-6"},{"key":"e_1_2_6_4_1","first-page":"387","volume-title":"Principles and practice of radiation oncology","author":"Grisby PW","year":"1997"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2004.09.058"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2005.102.4.0678"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00256-9"},{"key":"e_1_2_6_8_1","unstructured":"KimIH LimDH KimS et al.Extracranial doses during stereotactic radiosurgery and fractionated stereotactic radiotherapy measured with thermoluminescent dosimeter in vivo. 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