{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T05:42:33Z","timestamp":1792129353230,"version":"4.4.0"},"reference-count":53,"publisher":"Acoustical Society of America (ASA)","issue":"5","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2006,5,1]]},"abstract":"<jats:p>The time-course of the human medial olivocochlear reflex (MOCR) was measured via its suppression of stimulus-frequency otoacoustic emissions (SFOAEs) in nine ears. MOCR effects were elicited by contralateral, ipsilateral or bilateral wideband acoustic stimulation. As a first approximation, MOCR effects increased like a saturating exponential with a time constant of 277\u00b162ms, and decayed exponentially with a time constant of 159\u00b154ms. However, in ears with the highest signal-to-noise ratios (4\u22159), onset time constants could be separated into \u201cfast,\u201d \u03c4=\u223c70ms, \u201cmedium,\u201d \u03c4=\u223c330ms, and \u201cslow,\u201d \u03c4=\u223c25s components, and there was an overshoot in the decay like an under-damped sinusoid. Both the buildup and decay could be modeled as a second order differential equation and the differences between the buildup and decay could be accounted for by decreasing one coefficient by a factor of 2. The reflex onset and offset delays were both \u223c25ms. Although changing elicitor level over a 20dB SPL range produced a consistent systematic change in response amplitude, the time course did not show a consistent dependence on elictor level, nor did the time-courses of ipsilaterally, contralaterally, and bilaterally activated MOCR responses differ significantly. Given the MOCR\u2019s time-course, it is best suited to operate on acoustic changes that persist for 100\u2019s of milliseconds.<\/jats:p>","DOI":"10.1121\/1.2169918","type":"journal-article","created":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T13:10:22Z","timestamp":1146489022000},"page":"2889-2904","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":180,"title":["Time-course of the human medial olivocochlear reflex"],"prefix":"10.1121","volume":"119","author":[{"given":"Bradford C.","family":"Backus","sequence":"first","affiliation":[{"name":"Massachusetts Eye and Ear Infirmary Eaton Peabody Laboratory of Auditory Physiology, Department of Otolaryngology, , Boston, Massachusetts 02114 and Speech and Hearing Bioscience and Technology, , Cambridge, Massachusetts 02139"},{"name":"Harvard-MIT Division of Health Sciences and Technology Eaton Peabody Laboratory of Auditory Physiology, Department of Otolaryngology, , Boston, Massachusetts 02114 and Speech and Hearing Bioscience and Technology, , Cambridge, Massachusetts 02139"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"John J.","family":"Guinan","sequence":"additional","affiliation":[{"name":"Massachusetts Eye and Ear Infirmary Eaton Peabody Laboratory of Auditory Physiology, Department of Otolaryngology, , Boston, Massachusetts 02114, Speech and Hearing Bioscience and Technology, , Cambridge, Massachusetts 02139 and Department of Otology and Laryngology, , Boston, Massachusetts 02115"},{"name":"Harvard-MIT Division of Health Sciences and Technology Eaton Peabody Laboratory of Auditory Physiology, Department of Otolaryngology, , Boston, Massachusetts 02114, Speech and Hearing Bioscience and Technology, , Cambridge, Massachusetts 02139 and Department of Otology and Laryngology, , Boston, Massachusetts 02115"},{"name":"Harvard Medical School Eaton Peabody Laboratory of Auditory Physiology, Department of Otolaryngology, , Boston, Massachusetts 02114, Speech and Hearing Bioscience and Technology, , Cambridge, Massachusetts 02139 and Department of Otology and Laryngology, , Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","reference":[{"key":"2023073110173702800_c1","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/S0378-5955(03)00190-4","article-title":"Rapid adaptation of the 2f1-f2 DPOAE in humans: binaural and contralateral stimulation effects","volume":"182","year":"2003","journal-title":"Hear. 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