{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T02:40:37Z","timestamp":1691116837246},"reference-count":43,"publisher":"Acoustical Society of America (ASA)","issue":"4","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2008,10,1]]},"abstract":"<jats:p>The purpose of this research was to investigate the changes that occur in human distortion product otoacoustic emission (DPOAE) level functions over continuous frequency bands in response to activation of the medial olivocochlear (MOC) efferent system by contralateral broadband noise. DPOAEs were obtained using continuous upward ramps of the lower frequency tone (f1) while the higher frequency tone (f2) was fixed. These ramps were designed to change the stimulus frequency ratio f2\u2215f1 over a fixed range for each fixed f2 value of 2, 3, and 4kHz. Contralateral noise was presented on alternating ramps and the DPOAEs with and without contralateral noise were averaged separately. Stimulus frequency ratios of 1.10 and 1.22, and noise levels of 60 and 50dB sound pressure level (SPL) were employed. Changes in DPOAE level were generally suppression (a reduction in DPOAE magnitude), but enhancement was also observed. For most participants, changes were evident for much of the frequency ranges tested. Average absolute changes for 60dB SPL noise were 0.95, 0.81, and 0.42dB for the wider stimulus frequency ratios and f2 of 2, 3, and 4kHz, respectively. For the narrower ratio and 60dB SPL noise, the changes were larger with average absolute changes of 1.33, 1.09, and 0.87dB. For the narrower ratio and 50dB SPL noise, the changes were 1.08, 0.78, and 0.55dB with f2 of 2, 3, and 4kHz, respectively. DPOAE nulls were observed and a common response pattern was a shift of emission morphology to higher frequencies with contralateral acoustic stimulation. The method appears promising for relatively rapid evaluation of the MOC efferent system in humans and offers information complementary to measurement strategies that explore the effects of stimulus level.<\/jats:p>","DOI":"10.1121\/1.2973192","type":"journal-article","created":{"date-parts":[[2008,10,15]],"date-time":"2008-10-15T22:47:16Z","timestamp":1224110836000},"page":"2133-2148","update-policy":"http:\/\/dx.doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Distortion product otoacoustic emission contralateral suppression functions obtained with ramped stimuli"],"prefix":"10.1121","volume":"124","author":[{"given":"David W.","family":"Purcell","sequence":"first","affiliation":[{"name":"University of Western Ontario National Centre for Audiology, , 1201 Western Road, London, Ontario, N6G 1H1, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blake E.","family":"Butler","sequence":"additional","affiliation":[{"name":"University of Western Ontario National Centre for Audiology, , 1201 Western Road, London, Ontario, N6G 1H1, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy J.","family":"Saunders","sequence":"additional","affiliation":[{"name":"University of Western Ontario National Centre for Audiology, , 1201 Western Road, London, Ontario, N6G 1H1, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prudence","family":"Allen","sequence":"additional","affiliation":[{"name":"University of Western Ontario National Centre for Audiology, , 1201 Western Road, London, Ontario, N6G 1H1, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","reference":[{"key":"2023080402004552400_c1","doi-asserted-by":"publisher","first-page":"3726","DOI":"10.1121\/1.417234","article-title":"Distortion product otoacoustic emission (2f1-f2) amplitude as a function of f2\/f1 frequency ratio and primary tone level separation in human adults and neonates","volume":"100","year":"1996","journal-title":"J. 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