{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:31:16Z","timestamp":1759937476230},"reference-count":21,"publisher":"Acoustical Society of America (ASA)","issue":"2","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,2,1]]},"abstract":"<jats:p>Neuronal gain adaptation has been proposed as the underlying mechanism leading to the perception of phantom sounds such as Zwicker tones and tinnitus. In this gain-adaptation theory, cochlear compression plays a significant role with weaker compression leading to stronger phantom percepts. The specific aim of this study was to find a link between the strength of neuronal gain adaptation and cochlear compression. Compression was assessed using distortion product otoacoustic emissions (DPOAEs). Gain adaptation is hypothesized to manifest itself in the sensitization observed for the detection of masked tones when preceded by notched noise. Perceptual thresholds for pure tones in notched noise were measured at multiple frequencies following various priming signals. The observed sensitization was larger than expected from the combined effect of the various maskers. However, there was no link between sensitization and compression. Instead, across subjects, stronger sensitization correlated with stronger DPOAEs evoked by low-level primaries. In addition, growth of DPOAEs correlated reliably with perceptual thresholds across frequencies within subjects. Together, the data suggest that short-term dynamic adaptation leading to perceptual sensitization is the result of an active process mediated by the outer hair cells, which are thought to modulate the gain of the cochlear amplifier via efferent feedback.<\/jats:p>","DOI":"10.1121\/1.3277156","type":"journal-article","created":{"date-parts":[[2010,2,5]],"date-time":"2010-02-05T23:58:20Z","timestamp":1265414300000},"page":"970-976","update-policy":"http:\/\/dx.doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":9,"title":["Sensitization to masked tones following notched-noise correlates with estimates of cochlear function using distortion product otoacoustic emissions"],"prefix":"10.1121","volume":"127","author":[{"given":"Xiang","family":"Zhou","sequence":"first","affiliation":[{"name":"The City College of the City University of New York Department of Biomedical Engineering, , Steinman Hall, Room T-401, Convent Avenue, 140th Street, New York, New York 10031"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Henin","sequence":"additional","affiliation":[{"name":"City University of New York Speech and Hearing Sciences, Graduate Center, , 365 Fifth Avenue, New York, New York 10016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne E.","family":"Thompson","sequence":"additional","affiliation":[{"name":"City University of New York Speech and Hearing Sciences, Graduate Center, , 365 Fifth Avenue, New York, New York 10016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenis R.","family":"Long","sequence":"additional","affiliation":[{"name":"City University of New York Speech and Hearing Sciences, Graduate Center, , 365 Fifth Avenue, New York, New York 10016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas C.","family":"Parra","sequence":"additional","affiliation":[{"name":"The City College of the City University of New York Department of Biomedical Engineering, , Steinman Hall, Room T-401, Convent Avenue, 140th Street, New York, New York 10031"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","published-online":{"date-parts":[[2010,2,5]]},"reference":[{"key":"2023080104241284800_c1","volume-title":"Auditory Scene Analysis: The Perceptual Organization of Sound","year":"1990"},{"key":"2023080104241284800_c2","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/0378-5955(89)90014-2","article-title":"Changes in the masked thresholds of brief tones produced by prior bursts of noise","volume":"41","year":"1989","journal-title":"Hear. 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