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This hypothesis was tested experimentally in individuals with muscle tension dysphonia (MTD; N=10) and vocal nodules (N=10) relative to controls with healthy normal voice (N=10) who were examined with trans-nasal endoscopy during a simple vocal fold abductory-adductory task. Kinematic measures in MTD patients were less affected by increased gesture rate, consistent with the hypothesis that these individuals have elevated typical laryngeal muscle tension. Group comparisons of the difference between medium and fast gesture rates (Mann\u2013Whitney, one-tailed) showed statistically significant differences between the control and MTD individuals on the two kinematic features examined (p&amp;lt;0.05). Results in nodules participants were mixed and are discussed independently. The findings support the potential use of vocal fold kinematics as an objective clinical assay of vocal hyperfunction.<\/jats:p>","DOI":"10.1121\/1.3365257","type":"journal-article","created":{"date-parts":[[2010,5,13]],"date-time":"2010-05-13T21:47:47Z","timestamp":1273787267000},"page":"3166-3176","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":35,"title":["A virtual trajectory model predicts differences in vocal fold kinematics in individuals with vocal hyperfunction"],"prefix":"10.1121","volume":"127","author":[{"given":"Cara E.","family":"Stepp","sequence":"first","affiliation":[{"name":"Harvard-MIT Division of Health Sciences and Technology , Cambridge, Massachusetts 02139"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"Hillman","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital and Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, 11th Floor, One Bowdoin Square, Boston, Massachusetts 02114"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James T.","family":"Heaton","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital and Harvard Medical School, Center for Laryngeal Surgery and Voice Rehabilitation, 11th Floor, One Bowdoin Square, Boston, Massachusetts 02114"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","published-online":{"date-parts":[[2010,5,12]]},"reference":[{"key":"2023072522510041300_c1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1044\/jshr.3601.41","article-title":"Speaking rate and speech movement velocity profiles","volume":"36","year":"1993","journal-title":"J. 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