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During the GTT experiment, the subjects\u2019 blood glucose was elevated from a euglycemic level below 150\u2009mg\/dL to a hyperglycemic level above 160\u2009mg\/dL following the consumption of a bolus of 80\u2009g of sugar. A subset of three subjects were tested in a control experiment during which SF OAE and MOC reflex measurements were made while blood sugar levels remained constant within the euglycemic region. Mean SF OAE amplitudes were elevated following glucose consumption. A statistically significant increase in MOC inhibition amplitude was observed during elevated sugar levels for the 11 GTT trials. Maximum inhibition occurred about an hour after glucose consumption when blood glucose levels peaked. Results indicate that acute hyperglycemia influences efferent control of the cochlea in people with type 2 diabetes.<\/jats:p>","DOI":"10.1121\/1.3676609","type":"journal-article","created":{"date-parts":[[2012,2,15]],"date-time":"2012-02-15T13:36:48Z","timestamp":1329313008000},"page":"1296-1306","update-policy":"http:\/\/dx.doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":12,"title":["Influence of acute hyperglycemia on otoacoustic emissions and the medial olivocochlear reflex"],"prefix":"10.1121","volume":"131","author":[{"given":"Peter G.","family":"Jacobs","sequence":"first","affiliation":[{"name":"VA RR&D National Center for Rehabilitative Auditory Research, Portland VA Medical Center, 3710 SW U.S. Veterans Hospital Road, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn","family":"Konrad-Martin","sequence":"additional","affiliation":[{"name":"VA RR&D National Center for Rehabilitative Auditory Research, Portland VA Medical Center, 3710 SW U.S. Veterans Hospital Road, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garnett P.","family":"Mcmillan","sequence":"additional","affiliation":[{"name":"VA RR&D National Center for Rehabilitative Auditory Research, Portland VA Medical Center, 3710 SW U.S. Veterans Hospital Road, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"McDermott","sequence":"additional","affiliation":[{"name":"VA RR&D National Center for Rehabilitative Auditory Research, Portland VA Medical Center, 3710 SW U.S. Veterans Hospital Road, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Fausti","sequence":"additional","affiliation":[{"name":"VA RR&D National Center for Rehabilitative Auditory Research, Portland VA Medical Center, 3710 SW U.S. Veterans Hospital Road, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Kagen","sequence":"additional","affiliation":[{"name":"Portland VA Medical Center, Department of Medicine, 3710 SW U.S. Veterans Hospital Road, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric A.","family":"Wan","sequence":"additional","affiliation":[{"name":"Oregon Health and Science University , Department of Biomedical Engineering, 3303 SW Bond Avenue, Mail Code CH13B, Portland, Oregon 97239"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","published-online":{"date-parts":[[2012,2,14]]},"reference":[{"issue":"Suppl. 1","key":"2023080102351559700_c1","first-page":"S11","article-title":"Standards of medical care in diabetes\u20142011","volume":"34","author":"American Diabetes Association","year":"2011","journal-title":"ADA"},{"key":"2023080102351559700_c2","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1590\/S1808-86942009000500024","article-title":"Alterations in cochlear function during induced acute hyperinsulinemia in an animal model","volume":"75","year":"2009","journal-title":"Braz. 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