{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:45:31Z","timestamp":1790034331820,"version":"4.0.1"},"reference-count":0,"publisher":"Acoustical Society of America (ASA)","issue":"2","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1993,2,1]]},"abstract":"<jats:p>Recent research has revealed that repeated exposures to a low-frequency noise results in a progressive reduction in threshold shifts (TS). This reduction in TS is not restricted to the exposure frequency, but can be observed at frequencies up to 3 or 4 octave higher. Such \u2018\u2018conditioning\u2019\u2019 exposures have also been observed to protect the auditory system against hearing loss from exposures to the same noise at higher levels. The aim of this study was to determine if \u2018\u2018conditioning\u2019\u2019 using low-frequency exposures protects the auditory system against hearing loss from a high-frequency exposure. Monaural chinchillas were exposed to a 0.5-kHz octave band noise (OBN) at 95 dB SPL for 6 h a day. The animals were allowed to recover for 5 days, following which they were exposed to a 4-kHz OBN at 100 dB SPL for 48 h. Hearing thresholds determined using evoked potential recordings, indicated significantly greater permanent threshold shifts in this group of animals when compared to a control group exposed only to the 4-kHz OBN. These results were confirmed by histological examination which revealed greater hair cell loss in the experimental group.<\/jats:p>","DOI":"10.1121\/1.405455","type":"journal-article","created":{"date-parts":[[2005,10,13]],"date-time":"2005-10-13T21:47:23Z","timestamp":1129240043000},"page":"952-956","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Effect of low-frequency \u2018\u2018conditioning\u2019\u2019 on hearing loss from high-frequency exposure"],"prefix":"10.1121","volume":"93","author":[{"given":"Malini","family":"Subramaniam","sequence":"first","affiliation":[{"name":"Hearing Research Laboratory, Department of Communicative Disorders and Sciences, 215 Parker Hall, State University of New York, Buffalo, New York 14214"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Henderson","sequence":"additional","affiliation":[{"name":"Hearing Research Laboratory, Department of Communicative Disorders and Sciences, 215 Parker Hall, State University of New York, Buffalo, New York 14214"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vlasta","family":"Spongr","sequence":"additional","affiliation":[{"name":"Hearing Research Laboratory, Department of Communicative Disorders and Sciences, 215 Parker Hall, State University of New York, Buffalo, New York 14214"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","container-title":["The Journal of the Acoustical Society of America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.aip.org\/asa\/jasa\/article-pdf\/93\/2\/952\/11595658\/952_1_online.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.aip.org\/asa\/jasa\/article-pdf\/93\/2\/952\/11595658\/952_1_online.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T01:23:34Z","timestamp":1691112214000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.aip.org\/jasa\/article\/93\/2\/952\/969936\/Effect-of-low-frequency-conditioning-on-hearing"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,2,1]]}},"URL":"https:\/\/doi.org\/10.1121\/1.405455","relation":{},"ISSN":["0001-4966","1520-8524"],"issn-type":[{"value":"0001-4966","type":"print"},{"value":"1520-8524","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1993,2]]},"published":{"date-parts":[[1993,2,1]]}}}