{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T01:40:55Z","timestamp":1789868455372,"version":"4.0.1"},"reference-count":0,"publisher":"Acoustical Society of America (ASA)","issue":"4","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1993,4,1]]},"abstract":"<jats:p>There is evidence that the manner in which the central auditory system processes transient signals can be altered by either of two seemingly unrelated experimental factors, namely, hearing loss, or the presence of a continuous tone of moderate intensity. In particular, altered processing of brief signals in the central auditory system is indicated by either: (i) lower (better) behaviorally measured thresholds for pulsate electrical stimulation of brain-stem auditory nuclei, or (ii) an increased amplitude of some components of the brain stem or cortical potentials evoked by brief acoustic stimuli. A simple two-neuron model which evolved from the above findings and related visual system phenomena was used to evaluate the effects produced by hearing loss or continuous tone. In the model, a \u2018\u2018hearing loss\u2019\u2019 condition, which was represented by less spontaneous neural activity (and, hence, reduced inhibition) relative to a \u2018\u2018normal hearing\u2019\u2019 condition, yielded both increased gain for steady-state stimuli and increased responsiveness for transient stimuli. Thus the model provides two possible, and simultaneously operable, explanations of reduced electrical stimulation thresholds and increased evoked potential amplitude: one based on increased steady-state gain and the other based on increased responsiveness to transient stimuli. A third condition, \u2018\u2018normal hearing with a longer excitatory time constant,\u2019\u2019 yielded effects that were similar to those produced by reduced inhibition, thereby suggesting a physiological basis for alteration of psychophysically measured time constants.<\/jats:p>","DOI":"10.1121\/1.406690","type":"journal-article","created":{"date-parts":[[2005,10,13]],"date-time":"2005-10-13T21:47:23Z","timestamp":1129240043000},"page":"2038-2049","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":23,"title":["Alteration of central auditory processing of brief stimuli: A review and a neural model"],"prefix":"10.1121","volume":"93","author":[{"given":"George M.","family":"Gerken","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, The University of Texas Southwestern Medical Center, Dallas, Texas 75235-9035"},{"name":"The Callier Center for Communication Disorders, The University of Texas at Dallas, Dallas, Texas 75235-7298"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","container-title":["The Journal of the Acoustical Society of America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.aip.org\/asa\/jasa\/article-pdf\/93\/4\/2038\/11423051\/2038_1_online.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.aip.org\/asa\/jasa\/article-pdf\/93\/4\/2038\/11423051\/2038_1_online.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T06:23:05Z","timestamp":1691130185000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.aip.org\/jasa\/article\/93\/4\/2038\/968499\/Alteration-of-central-auditory-processing-of-brief"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,4,1]]}},"URL":"https:\/\/doi.org\/10.1121\/1.406690","relation":{},"ISSN":["0001-4966","1520-8524"],"issn-type":[{"value":"0001-4966","type":"print"},{"value":"1520-8524","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1993,4]]},"published":{"date-parts":[[1993,4,1]]}}}