{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T12:56:03Z","timestamp":1770468963776,"version":"3.49.0"},"reference-count":67,"publisher":"Acoustical Society of America (ASA)","issue":"4","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1998,10,1]]},"abstract":"<jats:p>Derived-band auditory brainstem responses (ABRs) were obtained in 43 normal-hearing and 80 cochlear hearing-impaired individuals using clicks and high-pass noise masking. The response times across the cochlea [the latency difference between wave V\u2019s of the 5.7- and 1.4-kHz center frequency (CF) derived bands] were calculated for five levels of click stimulation ranging from 53 to 93 dB p.-p.e. SPL (23 to 63 dB nHL) in 10-dB steps. Cochlear response times appeared to shorten significantly with hearing loss, especially when the average pure tone (1 to 8 kHz) hearing loss exceeded 30 dB. Examination of derived-band latencies indicates that this shortening is due to a dramatic decrease of wave V latency in the lower CF derived band. Estimates of cochlear filter times in terms of the number of periods to maximum response (Nmax) were calculated from derived-band latencies corrected for gender-dependent cochlear transport and neural conduction times. Nmax decreased as a function of hearing loss, especially for the low CF derived bands. The functions were similar for both males and females. These results are consistent with broader cochlear tuning due to peripheral hearing loss. Estimating filter response times from ABR latencies enhances objective noninvasive diagnosis and allows delineation of the differential effects of pathology on the underlying cochlear mechanisms involved in cochlear transport and filter build-up times.<\/jats:p>","DOI":"10.1121\/1.423741","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:05:41Z","timestamp":1027692341000},"page":"2280-2289","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":52,"title":["The effects of sensory hearing loss on cochlear filter times estimated from auditory brainstem response latencies"],"prefix":"10.1121","volume":"104","author":[{"given":"Manuel","family":"Don","sequence":"first","affiliation":[{"name":"Electrophysiology Laboratory, House Ear Institute, 2100 West Third Street, Los Angeles, California\u200990057"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curtis W.","family":"Ponton","sequence":"additional","affiliation":[{"name":"Electrophysiology Laboratory, House Ear Institute, 2100 West Third Street, Los Angeles, California\u200990057"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos J.","family":"Eggermont","sequence":"additional","affiliation":[{"name":"Departments of Physiology and Biophysics, and Psychology, University of Calgary, 2500 University Drive N.W., Calgary, Alberta T2N\u20091N4, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betty","family":"Kwong","sequence":"additional","affiliation":[{"name":"Electrophysiology Laboratory, House Ear Institute, 2100 West Third Street, Los Angeles, California\u200990057"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","reference":[{"key":"2023071409195775000_all83","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1121\/1.389575","article-title":"Magnitude and phase-frequency response to single tones in the auditory nerve","volume":"73","year":"1983","journal-title":"J. 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