{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T10:10:25Z","timestamp":1689329425442},"reference-count":41,"publisher":"Acoustical Society of America (ASA)","issue":"5","content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2000,5,1]]},"abstract":"<jats:p>Moderate acoustic trauma results in decreased cochlear sensitivity and frequency selectivity. This decrease is believed to be caused by damage to the cochlear amplifier that is associated with outer hair cells (OHCs) and their nonlinear electromechanical characteristics. A consequence of OHC nonlinearity is the acoustic enhancement effect, in which low-frequency electrically evoked otoacoustic emissions are enhanced by a simultaneous tone. The present study found that acoustic trauma reduced the acoustic enhancement effect and this reduction is correlated with the N1 threshold at the electrode site. This result is consistent with the theory that trauma affects the mechanoelectric transduction process, thus affecting cochlear mechanical nonlinearity. Acoustic trauma also reduced the cochlear microphonic in a way that suggests that the number of functioning tension-gated channels and the stiffness of the gating springs were decreased. In some cases, the electromechanical transduction process was also found to be affected by acoustic trauma.<\/jats:p>","DOI":"10.1121\/1.428647","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:08:44Z","timestamp":1027692524000},"page":"2603-2614","update-policy":"http:\/\/dx.doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Effects of acoustic trauma on acoustic enhancement of electrically evoked otoacoustic emissions"],"prefix":"10.1121","volume":"107","author":[{"given":"Hideko Heidi","family":"Nakajima","sequence":"first","affiliation":[{"name":"Hearing Research Center and Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts\u200902215"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allyn E.","family":"Hubbard","sequence":"additional","affiliation":[{"name":"Hearing Research Center and Department of Biomedical Engineering, Department of Electrical and Computer Engineering, and Department of Otolaryngology, Boston University, 44 Cummington Street, Boston, Massachusetts\u200902215"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Mountain","sequence":"additional","affiliation":[{"name":"Hearing Research Center and Department of Biomedical Engineering and Department of Otolaryngology, Boston University, 44 Cummington Street, Boston, Massachusetts\u200902215"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","reference":[{"key":"2023071409294670600_ash","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1113\/jphysiol.1987.sp016617","article-title":"A fast motile response in guinea pig outer hair cell: The cellular basis of the cochlear amplifier","volume":"388","year":"1987","journal-title":"J. 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