{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:26:35Z","timestamp":1787016395688,"version":"build-2736575974"},"reference-count":54,"publisher":"Acoustical Society of America (ASA)","issue":"4","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,10,1]]},"abstract":"<jats:p>The level-dependent component of the latency of human auditory brainstem responses (ABR) to tonebursts decreases by about 38% for every 20-dB increase in stimulus level over a wide range of both frequency and level [Neely, Norton, Gorga, and Jesteadt (1998). J. Acoust. Soc. Am. 31, 87\u201397]. This level-dependence has now been simulated in an active, nonlinear, transmission-line model of cochlear mechanics combined with an adaptation stage. The micromechanics in this model are similar to previous models except that a dual role is proposed for the tectorial membrane (TM): (1) passive sharpening the tuning of sensory-cell inputs (relative to basilar-membrane vibrations) and (2) providing an optimal phase shift (relative to basilar-membrane vibrations) of outer-hair-cell feedback forces, so that amplification is restricted to a limited range of frequencies. The adaptation stage, which represents synaptic adaptation of neural signals, contributes to the latency level-dependence more at low frequencies than at high frequencies. Compression in this model spans the range of audible sound levels with a compression ratio of about 2:1. With further development, the proposed model of cochlear micromechanics could be useful both (1) as a front-end to functional models of the auditory system and (2) as a foundation for understanding the physiological basis of cochlear amplification.<\/jats:p>","DOI":"10.1121\/1.5007719","type":"journal-article","created":{"date-parts":[[2017,10,19]],"date-time":"2017-10-19T09:40:24Z","timestamp":1508406024000},"page":"2155-2167","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Modeling signal propagation in the human cochlea"],"prefix":"10.1121","volume":"142","author":[{"given":"Stephen T.","family":"Neely","sequence":"first","affiliation":[{"name":"Boys Town National Research Hospital , 555 North 30th Street, Omaha, Nebraska 68131, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel M.","family":"Rasetshwane","sequence":"additional","affiliation":[{"name":"Boys Town National Research Hospital , 555 North 30th Street, Omaha, Nebraska 68131, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","published-online":{"date-parts":[[2017,10,19]]},"reference":[{"issue":"6","key":"2023072905215534600_c1","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1121\/1.385198","article-title":"Cochlear micromechanics\u2014A physical model of transduction","volume":"68","year":"1980","journal-title":"J. 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