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The literature on bone quantitative ultrasound suggests that ultrasonic waves are sensitive to multiple significant bone parameters such as mechanical properties, the bone volume fraction, and the micro-architecture. Typical ultrasound tomography techniques are limited to image objects with a low speed of sound contrast relative to a background medium. In this study, the possibility of adapting a more advanced ultrasound inversion technique referred to as the hybrid algorithm for robust breast ultrasound tomography for velocity mapping of bone mimicking phantoms was examined. The cortical bone thickness and the cortical bone speed of sound, which are directly related to the bone elastic properties, are parameters strongly correlated with the overall bone quality. A finite element model and an experimental test bench were developed to adapt the hybrid algorithm for robust breast ultrasound tomography to bone quality assessment. Although artefacts were present in the images generated, the results obtained enabled discrimination of a healthy bone phantom over an osteoporotic bone phantom based on the cortical bone thickness and the average cortical bone velocity. The speed of sound inside the cortical region of the bone phantoms was underestimated by 9.38% for the osteoporotic phantom, and by 10.68% for the healthy phantom relative to the values supplied by the bone phantom manufacturer, but there was a difference of 3.97% between the two samples. The difference between the measured cortical bone thickness of the reconstructed image and the X-ray computed tomography images was on average 0.4\u2009mm.<\/jats:p>","DOI":"10.1121\/1.5079533","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T15:24:50Z","timestamp":1543245890000},"page":"2937-2946","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["Ultrasound tomography in bone mimicking phantoms: Simulations and experiments"],"prefix":"10.1121","volume":"144","author":[{"given":"Timothe","family":"Falardeau","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, \u00c9cole de Technologie Sup\u00e9rieure , 1100 Notre-Dame Street West, Montreal, Quebec H3C1K3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Belanger","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, \u00c9cole de Technologie Sup\u00e9rieure , 1100 Notre-Dame Street West, Montreal, Quebec H3C1K3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","published-online":{"date-parts":[[2018,11,26]]},"reference":[{"key":"2023071904400141300_c1","doi-asserted-by":"publisher","first-page":"895474","DOI":"10.1155\/2013\/895474","article-title":"Comparison of QCT and DXA: Osteoporosis detection rates in postmenopausal women","volume":"2013","journal-title":"Int. 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