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A surface pattern containing size scales relevant to inhomogeneities of a porcine body wall was introduced between gel materials with fat- and muscle-like acoustic properties\u2014ballistic and polyvinyl alcohol gels. Here, the phantom design was refined to achieve relevant values of ultrasound absorption and scattering and make it more robust, facilitating frequent handling and use in various experimental arrangements. The fidelity of the interfacial surface of the fabricated phantom to the design was confirmed by three-dimensional ultrasound imaging. The HIFU field distortions\u2014displacement of the focus, enlargement of the focal region, and reduction of focal pressure\u2014produced by the phantom were characterized using hydrophone measurements with a 1.5\u2009MHz 256-element HIFU array and found to be similar to those induced by an ex vivo porcine body wall. A phase correction approach was used to mitigate the aberration effect on nonlinear focal waveforms and enable boiling histotripsy treatments through the phantom or body wall. The refined phantom represents a practical tool to explore HIFU therapy systems capabilities.<\/jats:p>","DOI":"10.1121\/10.0010369","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T12:22:13Z","timestamp":1651666933000},"page":"3007-3018","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":10,"title":["Robust and durable aberrative and absorptive phantom for therapeutic ultrasound applications"],"prefix":"10.1121","volume":"151","author":[{"given":"Alex T.","family":"Peek","sequence":"first","affiliation":[{"name":"Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington 1 , 1013 NE 40th Street, Seattle, Washington 98105, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles P. 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