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To estimate the time-varying model, a two-stage iterative least squares algorithm is proposed to reduce model overfitting. The efficacy of the proposed HNR estimator is demonstrated with synthetic signals, simulated tremor signals, and recorded acoustic signals. Results indicate that the proposed algorithm can produce consistent HNR measures as the extent and rate of tremor are varied.<\/jats:p>","DOI":"10.1121\/10.0014177","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T14:59:45Z","timestamp":1663772385000},"page":"1783-1794","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Harmonics-to-noise ratio estimation with deterministically time-varying harmonic model for pathological voice signals"],"prefix":"10.1121","volume":"152","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8151-0613","authenticated-orcid":false,"given":"Takeshi","family":"Ikuma","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Louisiana State University Health Sciences Center 1 , New Orleans, Louisiana 70112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6530-8781","authenticated-orcid":false,"given":"Brad","family":"Story","sequence":"additional","affiliation":[{"name":"Department of Speech, Language, and Hearing Sciences, University of Arizona 2 , Tucson, Arizona 85721, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"McWhorter","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Louisiana State University Health Sciences Center 1 , New Orleans, Louisiana 70112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4104-6270","authenticated-orcid":false,"given":"Lacey","family":"Adkins","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, Louisiana State University Health Sciences Center 1 , New Orleans, Louisiana 70112, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9699-9941","authenticated-orcid":false,"given":"Melda","family":"Kunduk","sequence":"additional","affiliation":[{"name":"Department of Communication Disorders, Louisiana State University 3 , Baton Rouge, Louisiana 70803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","published-online":{"date-parts":[[2022,9,21]]},"reference":[{"issue":"6","key":"2023081004194062100_c1","doi-asserted-by":"publisher","first-page":"1544","DOI":"10.1121\/1.387808","article-title":"Harmonics-to-noise ratio as an index of the degree of hoarseness","volume":"71","year":"1982","journal-title":"J. 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