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Both groups, subjects with and without COVID-19, are formed by Brazilian Portuguese speakers. Speech samples were obtained from 100 patients with mild to severe symptoms of COVID-19, and 100 healthy subjects. A single 31-syllable Portuguese sentence was used as the elicitation material for all subjects. The recordings were divided into four age groups. The acoustic measures were semi-automatically extracted and analyzed by a series of analyses of variance. Patients with COVID-19 present vocal differences in fo-related parameters when compared to healthy subjects, that is, patient voices presented higher fo and foSD with respect to control voices. In addition, for patient voices, there was an age and sex effect on fo SD values. Vocal parameters of women and elderly subjects showed more marked differences in fo-related parameters, indicating that patient voices are higher-pitched and have a higher variation of fo SD. Consequently, fo-related parameters may be tested as vocal biomarkers in the screening of respiratory insufficiency by voice analysis, in patients with severe symptoms of COVID-19.<\/jats:p>","DOI":"10.1121\/10.0016848","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T13:32:37Z","timestamp":1674739957000},"page":"576-585","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Fundamental frequency related parameters in Brazilians with COVID-19"],"prefix":"10.1121","volume":"153","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4144-2804","authenticated-orcid":false,"given":"Larissa Cristina","family":"Berti","sequence":"first","affiliation":[{"name":"Speech-Language Pathology and Audiology department, S\u00e3o Paulo State University 1 , Mar\u00edlia, S\u00e3o Paulo, 17525-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn Alves","family":"Spazzapan","sequence":"additional","affiliation":[{"name":"Speech-Language Pathology and Audiology department, S\u00e3o Paulo State University 1 , Mar\u00edlia, S\u00e3o Paulo, 17525-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Queiroz","sequence":"additional","affiliation":[{"name":"Computer Science Department, University of S\u00e3o Paulo 2 , S\u00e3o Paulo, S\u00e3o Paulo state, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Leyton","family":"Pereira","sequence":"additional","affiliation":[{"name":"Computer Science Department, University of S\u00e3o Paulo 2 , S\u00e3o Paulo, S\u00e3o Paulo state, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flaviane Romani","family":"Fernandes-Svartman","sequence":"additional","affiliation":[{"name":"Classic and Vernacular Letters Department, University of S\u00e3o Paulo 3 , S\u00e3o Paulo, S\u00e3o Paulo state, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz Raposo de","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Linguistics Department, University of S\u00e3o Paulo 4 , S\u00e3o Paulo, S\u00e3o Paulo State, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus Vin\u00edcius Moreira","family":"Martins","sequence":"additional","affiliation":[{"name":"Linguistics Department, University of S\u00e3o Paulo 4 , S\u00e3o Paulo, S\u00e3o Paulo State, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia Santiago","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Classic and Vernacular Letters Department, University of S\u00e3o Paulo 3 , S\u00e3o Paulo, S\u00e3o Paulo state, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid Gandolfi Gomes da","family":"Silva","sequence":"additional","affiliation":[{"name":"Classic and Vernacular Letters Department, University of S\u00e3o Paulo 3 , S\u00e3o Paulo, S\u00e3o Paulo state, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester Cerdeira","family":"Sabino","sequence":"additional","affiliation":[{"name":"Institute for Tropical Medicine (IMT), University of Sao Paulo 5 , S\u00e3o Paulo, S\u00e3o Paulo State, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Sara","family":"Levin","sequence":"additional","affiliation":[{"name":"Institute for Tropical Medicine (IMT), University of Sao Paulo 5 , S\u00e3o Paulo, S\u00e3o Paulo State, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Finger","sequence":"additional","affiliation":[{"name":"Computer Science Department, University of S\u00e3o Paulo 2 , S\u00e3o Paulo, S\u00e3o Paulo state, 05508-090, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","published-online":{"date-parts":[[2023,1,26]]},"reference":[{"issue":"6","key":"2023081021562384400_c1","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1016\/j.apmr.2021.01.063","article-title":"Swallowing and voice outcomes in patients hospitalized with COVID-19: An observational cohort study","volume":"102","year":"2021","journal-title":"Arch. 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