{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:29:42Z","timestamp":1790836182936,"version":"4.1.0"},"reference-count":62,"publisher":"Acoustical Society of America (ASA)","issue":"3","funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["K23 DC014752"],"award-info":[{"award-number":["K23 DC014752"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3,1]]},"abstract":"<jats:p>This study assessed whether the effects of contralateral acoustic stimulation (CAS) are consistent with eliciting the medial olivocochlear (MOC) reflex for measurements sensitive to outer hair cell (otoacoustic emissions, OAEs), auditory-nerve (AN; compound action potential, CAP), and brainstem\/cortical (envelope-following response, EFR) function. The effects of CAS were evaluated for simultaneous measurement of OAEs, CAPs, and EFRs in participants with normal hearing. Clicks were presented at 40 or 98\u2009Hz in three ipsilateral noise conditions (no noise, 45\u2009dB SPL, and 55\u2009dB SPL). For the no noise condition, CAS suppressed or enhanced EFR amplitudes for 40- and 98-Hz clicks, respectively, while CAS had no significant effect on CAP amplitudes. A follow-up experiment using slower rates (4.4\u201322.2\u2009Hz) assessed whether this insignificant CAS effect on CAPs was from ipsilateral MOC stimulation or AN adaptation; however, CAS effects remained insignificant despite favorable signal-to-noise ratios. CAS-related enhancements of EFR and CAP amplitudes in ipsilateral noise were not observed, contrary to the anti-masking effect of the MOC reflex. EFR and OAE suppression from CAS were not significantly correlated. Thus, the effects of CAS on EFRs may not be solely mediated by the MOC reflex and may be partially mediated by higher auditory centers.<\/jats:p>","DOI":"10.1121\/10.0025137","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T13:37:10Z","timestamp":1709732230000},"page":"1813-1824","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Effects of contralateral noise on envelope-following responses, auditory-nerve compound action potentials, and otoacoustic emissions measured simultaneously"],"prefix":"10.1121","volume":"155","author":[{"given":"Shelby L.","family":"Faubion","sequence":"first","affiliation":[{"name":"Department of Communication Sciences and Disorders, The University of Utah 1 , 390 South, 1530 East, BEHS 1201, Salt Lake City, Utah 84112, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan K.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Communication Sciences and Disorders, The University of Utah 1 , 390 South, 1530 East, BEHS 1201, Salt Lake City, Utah 84112, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery T.","family":"Lichtenhan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of South Florida Morsani College of Medicine 2 , Tampa, Florida 33612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7750-8396","authenticated-orcid":false,"given":"Skyler G.","family":"Jennings","sequence":"additional","affiliation":[{"name":"Department of Communication Sciences and Disorders, The University of Utah 1 , 390 South, 1530 East, BEHS 1201, Salt Lake City, Utah 84112, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","published-online":{"date-parts":[[2024,3,6]]},"reference":[{"key":"2024030613370616500_c1","doi-asserted-by":"publisher","first-page":"2889","DOI":"10.1121\/1.2169918","article-title":"Time-course of the human medial olivocochlear reflex","volume":"119","year":"2006","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0378-5955(93)90015-S","article-title":"Contralateral suppression of non-linear click-evoked otoacoustic emissions","volume":"71","year":"1993","journal-title":"Hear. Res."},{"key":"2024030613370616500_c3","doi-asserted-by":"publisher","first-page":"EL201","DOI":"10.1121\/10.0000627","article-title":"Noise-induced enhancement of envelope following responses in normal-hearing adults","volume":"147","year":"2020","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c4","doi-asserted-by":"publisher","first-page":"2598","DOI":"10.1016\/j.clinph.2008.08.002","article-title":"Generation of the 40-Hz auditory steady-state response (ASSR) explained using convolution","volume":"119","year":"2008","journal-title":"Clin. Neurophysiol."},{"key":"2024030613370616500_c5","doi-asserted-by":"publisher","first-page":"12693","DOI":"10.1038\/s41598-023-39850-8","article-title":"Auditory brainstem mechanisms likely compensate for self-imposed peripheral inhibition","volume":"13","year":"2023","journal-title":"Sci. Rep."},{"key":"2024030613370616500_c6","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1121\/1.4906250","article-title":"Influence of the stimulus presentation rate on medial olivocochlear system assays","volume":"137","year":"2015","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c7","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s10162-022-00865-z","article-title":"Temporal envelope coding of the human auditory nerve inferred from electrocochleography: Comparison with envelope following responses","volume":"23","year":"2022","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"2024030613370616500_c8","doi-asserted-by":"publisher","first-page":"2992","DOI":"10.1121\/1.3372756","article-title":"Click- and chirp-evoked human compound action potentials","volume":"127","year":"2010","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/0-387-21530-1_1","article-title":"Compression in the peripheral auditory system","volume-title":"Compression: From Cochlea to Cochlear Implants","author":"Bacon","year":"2004"},{"key":"2024030613370616500_c10","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1121\/1.381214","article-title":"Analysis of compound action potential responses to tone bursts in the human and guinea pig cochlea","volume":"60","year":"1976","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c11","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1121\/1.382345","article-title":"Narrow-band AP latencies in normal and recruiting human ears","volume":"65","year":"1979","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c12","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1007\/s10162-011-0260-9","article-title":"Effects of electrical stimulation of olivocochlear fibers in cochlear potentials in the chinchilla","volume":"12","year":"2011","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"2024030613370616500_c13","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1037\/xhp0000115","article-title":"New perspectives on the measurement and time course of auditory enhancement","volume":"41","year":"2015","journal-title":"J. Exp. Psychol. Hum. Percept. Perform."},{"key":"2024030613370616500_c14","doi-asserted-by":"publisher","first-page":"262","DOI":"10.3109\/00016488709107281","article-title":"N1 action potentials in humans: Influence of simultaneous contralateral stimulation","volume":"103","year":"1987","journal-title":"Acta Oto-Laryngol."},{"key":"2024030613370616500_c15","doi-asserted-by":"publisher","first-page":"7372","DOI":"10.1523\/JNEUROSCI.21-18-07372.2001","article-title":"Cholinergic modulation of stellate cells in the mammalian ventral cochlear nucleus","volume":"21","year":"2001","journal-title":"J. Neurosci."},{"key":"2024030613370616500_c16","doi-asserted-by":"publisher","first-page":"2683","DOI":"10.1121\/1.404383","article-title":"Physiological studies of central masking in man. I: The effects of noise on the 40-Hz steady-state response","volume":"92","year":"1992","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c17","doi-asserted-by":"publisher","first-page":"1938","DOI":"10.1152\/jn.00410.2020","article-title":"Medial olivocochlear reflex effects on amplitude growth functions of long- and short-latency components of click-evoked otoacoustic emissions in humans","volume":"125","year":"2021","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c18","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s10162-023-00888-0","article-title":"Minimum detectable differences in electrocochleography measurements: Bayesian-based predictions","volume":"24","year":"2023","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"2024030613370616500_c19","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1007\/s10162-013-0409-9","article-title":"Medial olivocochlear-induced transient-evoked otoacoustic emission amplitude shifts in individual subjects","volume":"14","year":"2013","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"2024030613370616500_c20","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/978-1-4612-0757-3","article-title":"Physiology of the olivocochlear efferents","volume-title":"The Cochlea","author":"Dallos","year":"1996"},{"key":"2024030613370616500_c21","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s10162-002-3037-3","article-title":"Medial olivocochlear efferent reflex in humans: Otoacoustic emission (OAE) measurement issues and the advantages of stimulus frequency OAEs","volume":"4","year":"2003","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"2024030613370616500_c22","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0378-5955(96)00138-4","article-title":"Contralateral suppression of transient-evoked otoacoustic emissions in humans: Intensity effects","volume":"101","year":"1996","journal-title":"Hear. Res."},{"key":"2024030613370616500_c23","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0378-5955(94)90030-2","article-title":"Development of contralateral suppression of the VIIIth nerve compound action potential (CAP) in the Mongolian gerbil","volume":"78","year":"1994","journal-title":"Hear. Res."},{"key":"2024030613370616500_c24","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1121\/10.0017604","article-title":"Middle ear muscle and medial olivocochlear activity inferred from individual human ears via cochlear potentials","volume":"153","year":"2023","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c25","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1152\/physrev.00029.2003","article-title":"Neural processing of amplitude-modulated sounds","volume":"84","year":"2004","journal-title":"Physiol. Rev."},{"key":"2024030613370616500_c26","doi-asserted-by":"publisher","first-page":"2533","DOI":"10.1152\/jn.1993.70.6.2533","article-title":"Antimasking effects of the olivocochlear reflex. II. Enhancement of auditory-nerve response to masked tones","volume":"70","year":"1993","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c27","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.1152\/jn.1993.70.6.2519","article-title":"Antimasking effects of the olivocochlear reflex.1. Enhancement of compound action-potentials to masked tones","volume":"70","year":"1993","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c28","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1152\/jn.2000.84.1.255","article-title":"Auditory temporal processing: Responses to sinusoidally amplitude-modulated tones in the inferior colliculus","volume":"84","year":"2000","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c29","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1055\/s-0040-1715963","article-title":"Sources of the scalp-recorded amplitude-modulation following response","volume":"13","year":"2002","journal-title":"J. Am. Acad. Audiol."},{"key":"2024030613370616500_c30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.heares.2009.02.002","article-title":"Slow build-up of cochlear suppression during sustained contralateral noise: Central modulation of olivocochlear efferents?","volume":"256","year":"2009","journal-title":"Hear. Res."},{"key":"2024030613370616500_c31","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1152\/jn.00677.2018","article-title":"Cochlear compound action potentials from high-level tone bursts originate from wide cochlear regions that are offset toward the most sensitive cochlear region","volume":"121","year":"2019","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c32","doi-asserted-by":"publisher","first-page":"9560","DOI":"10.1523\/JNEUROSCI.3004-18.2019","article-title":"Cochlear efferent innervation is sparse in humans and decreases with age","volume":"39","year":"2019","journal-title":"J. Neurosci."},{"key":"2024030613370616500_c33","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1152\/jn.1988.60.5.1779","article-title":"Response properties of cochlear efferent neurons: Monaural vs. binaural stimulation and the effects of noise","volume":"60","year":"1988","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c34","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/0378-5955(89)90127-5","article-title":"Rapid assessment of sound-evoked olivocochlear feedback: Suppression of compound action potentials by contralateral sound","volume":"38","year":"1989","journal-title":"Hear. Res."},{"key":"2024030613370616500_c35","doi-asserted-by":"publisher","first-page":"3572","DOI":"10.1121\/1.414956","article-title":"The ipsilaterally evoked olivocochlear reflex causes rapid adaptation of the 2f1\u2013f2 distortion product otoacoustic emission","volume":"99","year":"1996","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c36","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.heares.2015.09.001","article-title":"Medial olivocochlear efferent reflex inhibition of human cochlear nerve responses","volume":"333","year":"2016","journal-title":"Hear. Res."},{"key":"2024030613370616500_c37","first-page":"409","article-title":"Consciousness and the thalamocortical loop","volume-title":"International Congress Series","year":"2003"},{"key":"2024030613370616500_c38","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1097\/AUD.0b013e3181acfb57","article-title":"Effects of contralateral noise on 40-Hz and 80-Hz auditory steady-state responses","volume":"30","year":"2009","journal-title":"Ear. Hear."},{"key":"2024030613370616500_c39","first-page":"89","article-title":"Tympanometry: Basic principles and clinical applications","volume-title":"Contemporary Perspectives in Hearing Assessment","author":"Musiek","year":"1999"},{"key":"2024030613370616500_c40","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/0378-5955(95)00200-6","article-title":"Generators of the brainstem auditory evoked potential in cat. III: Identified cell populations","volume":"93","year":"1996","journal-title":"Hear. Res."},{"key":"2024030613370616500_c41","doi-asserted-by":"publisher","first-page":"e72","DOI":"10.1097\/AUD.0000000000000244","article-title":"Within- and across-subject variability of repeated measurements of medial olivocochlear-induced changes in transient-evoked otoacoustic emissions","volume":"37","year":"2016","journal-title":"Ear. Hear."},{"key":"2024030613370616500_c42","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.1121\/1.4962666","article-title":"Concurrent measures of contralateral suppression of transient-evoked otoacoustic emissions and of auditory steady-state responses","volume":"140","year":"2016","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c43","doi-asserted-by":"publisher","first-page":"2255","DOI":"10.1121\/10.0009910","article-title":"Contralateral noise effects on otoacoustic emissions and electrophysiologic responses in normal-hearing adults","volume":"151","year":"2022","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c44","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3766\/jaaa.15002","article-title":"The effect of contralateral pure tones on the compound action potential in humans: Efferent tuning curves","volume":"27","year":"2016","journal-title":"J. Am. Acad. Audiol."},{"key":"2024030613370616500_c45","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0014-4886(70)90172-X","article-title":"Antimasking effect of crossed olivocochlear bundle stimulation with loud clicks in guinea pig","volume":"28","year":"1970","journal-title":"Exp. Neurol."},{"key":"2024030613370616500_c46","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.1016\/j.clinph.2008.03.023","article-title":"Suppression of the Pb (P1) component of the auditory middle latency response with contralateral masking","volume":"119","year":"2008","journal-title":"Clin. Neurophysiol."},{"key":"2024030613370616500_c47","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/S0378-5955(00)00244-6","article-title":"Effects of contralateral acoustical stimulation on three measures of cochlear function in the guinea pig","volume":"152","year":"2001","journal-title":"Hear. Res."},{"key":"2024030613370616500_c48","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.clinph.2012.05.009","article-title":"Objective measurement of physiological signal-to-noise gain in the brainstem response to a synthetic vowel","volume":"124","year":"2013","journal-title":"Clin. Neurophysiol."},{"key":"2024030613370616500_c49","doi-asserted-by":"publisher","first-page":"3581","DOI":"10.1121\/1.1798354","article-title":"Human temporal auditory acuity as assessed by envelope following responses","volume":"116","year":"2004","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c50","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1121\/1.414508","article-title":"Olivocochlear reflex assays: Effects of contralateral sound on compound action potentials versus ear-canal distortion products","volume":"99","year":"1996","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c51","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1007\/s101620010029","article-title":"Rate representation of tones in noise in the inferior colliculus of decerebrate cats","volume":"1","year":"2000","journal-title":"J. Assoc. Res. Otolaryngol."},{"key":"2024030613370616500_c52","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1002\/cne.900840204","article-title":"The olivary peduncle and other fiber projections of the superior olivary complex","volume":"84","year":"1946","journal-title":"J. Compar. Neurol."},{"key":"2024030613370616500_c53","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.conb.2009.07.006","article-title":"Gain control mechanisms in the auditory pathway","volume":"19","year":"2009","journal-title":"Curr. Opin. Neurobiol."},{"key":"2024030613370616500_c54","doi-asserted-by":"publisher","first-page":"4082","DOI":"10.1152\/jn.00469.2005","article-title":"Stimulus induced desynchronization of human auditory 40-Hz steady-state responses","volume":"94","year":"2005","journal-title":"J. Neurophysiol."},{"key":"2024030613370616500_c55","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/S0378-5955(02)00285-X","article-title":"Temporal integration in the human auditory cortex as represented by the development of the steady-state magnetic field","volume":"165","year":"2002","journal-title":"Hear. Res."},{"key":"2024030613370616500_c56","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3389\/fnsys.2020.00018","article-title":"Techniques for obtaining high-quality recordings in electrocochleography","volume":"14","year":"2020","journal-title":"Front. Syst. Neurosci."},{"key":"2024030613370616500_c57","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1121\/1.428274","article-title":"Psychophysical correlates of contralateral efferent suppression. I. The role of the medial olivocochlear system in \u2018central masking\u2019 in nonhuman primates","volume":"107","year":"2000","journal-title":"J. Acoust. Soc. Am."},{"key":"2024030613370616500_c58","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.heares.2017.10.009","article-title":"Efferent modulation of pre-neural and neural distortion products","volume":"356","year":"2017","journal-title":"Hear. Res."},{"key":"2024030613370616500_c59","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3389\/fnins.2017.00189","article-title":"Contralateral inhibition of click- and chirp-evoked human compound action potentials","volume":"11","year":"2017","journal-title":"Front. Neurosci."},{"key":"2024030613370616500_c60","doi-asserted-by":"publisher","first-page":"3667","DOI":"10.1523\/JNEUROSCI.15-05-03667.1995","article-title":"A novel cholinergic \u2018slow effect\u2019 of efferent stimulation on cochlear potentials in the guinea pig","volume":"15","year":"1995","journal-title":"J. Neurosci."},{"key":"2024030613370616500_c61","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.heares.2004.11.014","article-title":"The effects of nembutal anesthesia on the auditory steady-state response (ASSR) from the inferior colliculus and auditory cortex of the chinchilla","volume":"203","year":"2005","journal-title":"Hear. Res."},{"key":"2024030613370616500_c62","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1121\/1.1912235","article-title":"Variations in the effects of electric stimulation of the crossed olivocochlear bundle on cat single auditory-nerve-fiber responses to tone bursts","volume":"48","year":"1970","journal-title":"J. Acoust. Soc. Am."}],"container-title":["The Journal of the Acoustical Society of America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.aip.org\/asa\/jasa\/article-pdf\/155\/3\/1813\/19712223\/1813_1_10.0025137.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.aip.org\/asa\/jasa\/article-pdf\/155\/3\/1813\/19712223\/1813_1_10.0025137.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T13:37:16Z","timestamp":1709732236000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.aip.org\/jasa\/article\/155\/3\/1813\/3268697\/Effects-of-contralateral-noise-on-envelope"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,1]]},"references-count":62,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3,1]]}},"URL":"https:\/\/doi.org\/10.1121\/10.0025137","relation":{},"ISSN":["0001-4966"],"issn-type":[{"value":"0001-4966","type":"print"}],"subject":[],"published-other":{"date-parts":[[2024,3]]},"published":{"date-parts":[[2024,3,1]]}}}