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By marking acoustic prominence, speakers distinguish new from given information in speech. While a large body of relevant literature exists on how acoustic prominence is acoustically realized in typically developing (TD) children, little is known about how children with Down syndrome (DS) mark it. In this study, a \u201cPuppet Show\u201d task was conducted with 22 TD children and ten children with DS, one of whom was excluded because they were unable to produce the required target utterances despite multiple attempts, to compare the acoustic parameters used when distinguishing new and given information, focusing on mean f0, mean intensity, duration, and time-normalized f0. By using linear mixed-effects models and generalized additive mixed models, we demonstrated that children with DS have significantly higher overall mean f0 and lower intensity compared to TD children. The duration was not significantly different between the two groups. Our analysis further revealed distinct f0 contour patterns in the speech of DS children. While TD children exhibited clear rising and falling f0 contours to signal new and given information, DS children showed less controlled f0 contour patterns.<\/jats:p>","DOI":"10.1121\/10.0039045","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:37:43Z","timestamp":1756294663000},"page":"1538-1550","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":1,"title":["Acoustic prominence: Understanding speech patterns in children with Down syndrome"],"prefix":"10.1121","volume":"158","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5389-1706","authenticated-orcid":false,"given":"Delin","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Psychology and Human Development, Vanderbilt University 1 , Nashville, Tennessee 37235,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4362-3032","authenticated-orcid":false,"given":"Miriam","family":"Lense","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Vanderbilt University 2 , Nashville, Tennessee 37235,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3342-1747","authenticated-orcid":false,"given":"Stephen","family":"Camarata","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Vanderbilt University 2 , Nashville, Tennessee 37235,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Mazzone","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Vanderbilt University 2 , Nashville, Tennessee 37235,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4552-1439","authenticated-orcid":false,"given":"Doriana","family":"Lacitignola","sequence":"additional","affiliation":[{"name":"Department of Psychology and Human Development, Vanderbilt University 1 , Nashville, Tennessee 37235,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duane","family":"Watson","sequence":"additional","affiliation":[{"name":"Department of Psychology and Human Development, Vanderbilt University 1 , Nashville, Tennessee 37235,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"231","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"issue":"2","key":"2025082707373578800_c1","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1044\/jslhr.4302.441","article-title":"Production of sentence-final intonation contours by hearing-impaired children","volume":"43","year":"2000","journal-title":"J. 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