{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:09:44Z","timestamp":1773706184679,"version":"3.50.1"},"reference-count":22,"publisher":"Acoustical Society of America (ASA)","issue":"3","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171156"],"award-info":[{"award-number":["82171156"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32371051"],"award-info":[{"award-number":["32371051"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National High Level Hospital Clinical Research Funding","award":["2022-PUMCH-A-002"],"award-info":[{"award-number":["2022-PUMCH-A-002"]}]},{"name":"National High Level Hospital Clinical Research Funding","award":["2022-PUMCH-B-095"],"award-info":[{"award-number":["2022-PUMCH-B-095"]}]}],"content-domain":{"domain":["pubs.aip.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:p>Long testing durations are the major challenge in the clinical application of auditory brainstem response (ABR), and simultaneous bilateral testing is a potential solution. However, when identical stimuli are presented to both ears simultaneously, binaural interactions occur, complicating the identification of each ear's true response. Thus, this study applies the spread spectrum technology to ABR testing by employing a random stimulus rate for each ear, enabling simultaneous and independent assessment of bilateral ears (ssBi-ABR). The ssBi-ABR results were compared with traditional unilateral auditory brainstem response (uABR) results to examine the effectiveness of the ssBi-ABR method. No significant difference in the response threshold was observed between the two methods. Although ssBi-ABR showed significantly longer latencies (except wave I) and lower amplitudes than uABR, the average differences were both relatively small (&amp;lt;0.1\u2009ms and &amp;lt;0.1\u2009\u03bcV). The testing duration of ssBi-ABR was significantly shorter than that of uABR, on average, requiring only 63% of the time needed for uABR. The findings demonstrate that the application of spread spectrum technology enables effective and simultaneous bilateral ABR testing, which could significantly reduce the testing time without compromising the accuracy of the results.<\/jats:p>","DOI":"10.1121\/10.0039098","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T15:22:25Z","timestamp":1756826545000},"page":"1646-1652","update-policy":"https:\/\/doi.org\/10.1063\/aip-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Study of simultaneous bilateral auditory brainstem response recordings based on spread spectrum technology"],"prefix":"10.1121","volume":"158","author":[{"given":"Suju","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayan","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingya","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingying","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"231","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"2025090211222355300_c1","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/0013-4694(80)90223-0","article-title":"Comparison of brain stem auditory evoked potentials for monaural and binaural stimuli","volume":"49","year":"1980","journal-title":"Electroencephalogr. 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