{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:38:20Z","timestamp":1770741500772,"version":"3.49.0"},"reference-count":43,"publisher":"Human Kinetics","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:p>Enhanced buffering capacity following sodium citrate (SC) ingestion may be optimized when subsequent exercise commences at individual time-to-peak (TTP) alkalosis (blood pH or bicarbonate concentration [HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup>]). While accounting for considerable interindividual variation in TTP (188\u2013300\u00a0min), a reliable blood alkalotic response is required for practical use. This study evaluated the reliability of blood pH, HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup>, and sodium (Na<jats:sup>+<\/jats:sup>) following acute SC ingestion. Fourteen recreationally active males ingested 0.4 or 0.5\u00a0g\/kg\u00a0body mass (BM) of SC on two occasions each and 0.07\u00a0g\/kg\u00a0BM of sodium chloride (control) once. Blood pH and HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup> were measured for 4\u00a0hr postingestion. Blood pH and HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup> displayed good reliability following 0.5\u00a0g\/kg\u00a0BM SC (<jats:italic>r<\/jats:italic>\u2009=\u2009.819, <jats:italic>p<\/jats:italic>\u2009=\u2009.002, standardized technical error [sTE]\u2009=\u20090.67 and <jats:italic>r<\/jats:italic>\u2009=\u2009.840, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001, sTE\u2009=\u20090.63, respectively). Following 0.4\u00a0g\/kg\u00a0BM SC, blood HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup> retained good reliability (<jats:italic>r<\/jats:italic>\u2009=\u2009.771, <jats:italic>p<\/jats:italic>\u2009=\u2009.006, sTE\u2009=\u20090.78) versus moderate for blood pH (<jats:italic>r<\/jats:italic>\u2009=\u2009.520, <jats:italic>p<\/jats:italic>\u2009=\u2009.099, sTE\u2009=\u20091.36). TTP pH was moderately reliable following 0.5 (<jats:italic>r<\/jats:italic>\u2009=\u2009.676, <jats:italic>p<\/jats:italic>\u2009=\u2009.026, sTE\u2009=\u20091.05) and 0.4\u00a0g\/kg\u00a0BM SC (<jats:italic>r<\/jats:italic>\u2009=\u2009.679, <jats:italic>p<\/jats:italic>\u2009=\u2009.025, sTE\u2009=\u20090.91) versus poor for HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup> following 0.5 (<jats:italic>r<\/jats:italic>\u2009=\u2009.183, <jats:italic>p<\/jats:italic>\u2009=\u2009.361, sTE\u2009=\u20095.38) and 0.4\u00a0g\/kg\u00a0BM SC (<jats:italic>r<\/jats:italic>\u2009=\u2009.290, <jats:italic>p<\/jats:italic>\u2009=\u2009.273, sTE\u2009=\u20092.50). Although the magnitude of (and displacement in) blood alkalosis, particularly HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup>, appears reliable following potentially ergogenic doses of SC, strategies based on individual TTP cannot be recommended.<\/jats:p>","DOI":"10.1123\/ijsnem.2024-0122","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T19:46:51Z","timestamp":1732304811000},"page":"131-139","source":"Crossref","is-referenced-by-count":1,"title":["The Magnitude of the Blood Acid\u2013Base Response, but Not Time to Peak, Is Reliable Following the Ingestion of Acute, Individualized Sodium Citrate"],"prefix":"10.1123","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3116-0985","authenticated-orcid":true,"given":"Daniel J.","family":"Tinnion","sequence":"first","affiliation":[{"name":"Department of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0413-878X","authenticated-orcid":true,"given":"Ben","family":"Dobson","sequence":"additional","affiliation":[{"name":"Department of Sport and Physical Activity, Edge Hill University, Ormskirk, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0204-8967","authenticated-orcid":true,"given":"Nathan","family":"Hilton","sequence":"additional","affiliation":[{"name":"Medical School, Edge Hill University, Ormskirk, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3743-3171","authenticated-orcid":true,"given":"Lars R.","family":"McNaughton","sequence":"additional","affiliation":[{"name":"Department of Sport and Physical Activity, Edge Hill University, Ormskirk, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0910-2225","authenticated-orcid":true,"given":"S. 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