{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:33:06Z","timestamp":1759962786510},"reference-count":0,"publisher":"Human Kinetics","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:sec sec-type=\"purpose\"><jats:title>Purpose:<\/jats:title><jats:p>To investigate the effects of polysaccharide from <jats:italic>Gynostemma pentaphyllum<\/jats:italic> on antioxidant activity in skeletal muscle of mice exercised to exhaustion.<\/jats:p><\/jats:sec><jats:sec sec-type=\"methods\"><jats:title>Methods:<\/jats:title><jats:p>Three polysaccharide fractions were obtained from <jats:italic>G. pentaphyllum<\/jats:italic> polysaccharide (GPP) and termed GPP1-a, GPP2-b, and GPP3-a. Gas chromatography (GC) and infrared spectrum of the polysaccharides were determined. The fractions were orally administrated to mice once daily for 1 wk. The exercise time to exhaustion was assessed using a forced swim test of mice after a week. The glucose, creatine phosphokinase, and lactic dehydrogenase in serum; the activity of superoxide dismutase and glutathione peroxidase; and the levels of malondialdehyde (MDA) and glycogen in muscle were determined.<\/jats:p><\/jats:sec><jats:sec sec-type=\"results\"><jats:title>Results:<\/jats:title><jats:p>The results of GC demonstrated that GPP1-a, GPP2-b, and GPP3-a were composed of different monosaccharides with distinct molar ratios. Infrared spectrum showed that the main typicals of GPP1-a and GPP2-b were \u03b2-configuration and the main typical of GPP3-a was \u03b1-configuration. Among the 3 fractions of GPP, GPP1-a administration significantly prolonged exercise time to exhaustion of mice, increased glycogen level and some of antioxidant enzyme activities, and decreased MDA level in muscle.<\/jats:p><\/jats:sec><jats:sec sec-type=\"conclusions\"><jats:title>Conclusions:<\/jats:title><jats:p>The mechanism by which GPP1-a prolonged exercise time to exhaustion in mice may be associated with scavenging reactive oxygen species excessively produced and further increasing glycogen levels in skeletal muscle.<\/jats:p><\/jats:sec>","DOI":"10.1123\/ijsnem.22.6.479","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T12:32:46Z","timestamp":1470832366000},"page":"479-485","source":"Crossref","is-referenced-by-count":18,"title":["Chemical Composition of Three Polysaccharides From Gynostemma pentaphyllum and Their Antioxidant Activity in Skeletal Muscle of Exercised Mice"],"prefix":"10.1123","volume":"22","author":[{"given":"Aiping","family":"Chi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunru","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"100","container-title":["International Journal of Sport Nutrition and Exercise Metabolism"],"original-title":[],"link":[{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/ijsnem\/22\/6\/article-p479.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/ijsnem\/22\/6\/article-p479.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/ijsnem\/22\/6\/article-p479.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T02:11:40Z","timestamp":1724292700000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/ijsnem\/22\/6\/article-p479.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":0,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1123\/ijsnem.22.6.479","relation":{},"ISSN":["1526-484X","1543-2742"],"issn-type":[{"type":"print","value":"1526-484X"},{"type":"electronic","value":"1543-2742"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}