{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:57:12Z","timestamp":1789469832174,"version":"build-2803163510"},"reference-count":60,"publisher":"Human Kinetics","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,9,1]]},"abstract":"<jats:p><jats:italic><jats:bold>Context<\/jats:bold>:<\/jats:italic> Of the 3 branched-chain amino acids (BCAA), leucine has arguably received the most attribution for the role of BCAA supplementation in alleviating symptoms of exercise-induced muscle damage and facilitation of acute performance recovery. <jats:italic><jats:bold>Purpose<\/jats:bold>:<\/jats:italic> To examine whether enrichment of a standard BCAA supplement with additional leucine or a standalone leucine (LEU) supplement differentially affects exercise-induced muscle damage and performance recovery compared with a standard BCAA supplement. <jats:italic><jats:bold>Methods<\/jats:bold>:<\/jats:italic> A total of 22 recreationally active male and female subjects were recruited and assigned to consume a BCAA, leucine-enriched BCAA (LBCAA), or LEU supplement for 11 d. On the eighth day, subjects performed eccentric-based resistance exercise (ECRE). Lower-body mean average and peak power, plasma creatine kinase, soreness, and pain threshold were measured before and 24, 48, and 72\u00a0h after ECRE. <jats:italic><jats:bold>Results<\/jats:bold>:<\/jats:italic> LEU showed decreased mean average power (<jats:italic>P<\/jats:italic>\u2009=\u2009.02) and mean peak power (<jats:italic>P<\/jats:italic>\u2009=\u2009.01) from baseline to 48\u00a0h post-ECRE, whereas LBCAA and BCAA only trended toward a reduction at 24 hours post-ECRE. At 48\u00a0h post-ECRE, BCAA showed greater recovery of mean peak power than LEU (<jats:italic>P<\/jats:italic>\u2009=\u2009.04). At 24\u00a0h post-ECRE, LEU demonstrated a greater increase in plasma creatine kinase from baseline than BCAA (<jats:italic>P<\/jats:italic>\u2009=\u2009.04). Area under the curve for creatine kinase was greater in LEU than BCAA (<jats:italic>P<\/jats:italic>\u2009=\u2009.02), whereas BCAA and LBCAA did not differ. Only LEU demonstrated increased soreness during rest and under muscular tension at 24 and 48 h post-ECRE (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). <jats:italic><jats:bold>Conclusions<\/jats:bold>:<\/jats:italic> LBCAA failed to afford any advantages over a standard BCAA supplement for postexercise muscle recovery, whereas a LEU supplement was comparatively ineffective.<\/jats:p>","DOI":"10.1123\/ijspp.2018-0579","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T15:47:44Z","timestamp":1559922464000},"page":"1081-1088","source":"Crossref","is-referenced-by-count":22,"title":["The Effects of Leucine-Enriched Branched-Chain Amino Acid Supplementation on Recovery After High-Intensity Resistance Exercise"],"prefix":"10.1123","volume":"14","author":[{"given":"Adam D.","family":"Osmond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean 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