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In addition, power output relative to peak power was higher in females at LT1 and LT2 (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). However, heart rate was higher in females than males at LT1 and LT2 (<jats:italic>P<\/jats:italic>\u2009=\u2009.008). Furthermore, the heart rate relative to maximal heart rate was higher in females compared with males at LT1 and LT2 (<jats:italic>P<\/jats:italic>\u2009=\u2009.002). <jats:italic><jats:bold>Conclusion<\/jats:bold>:<\/jats:italic> Females and males may be in a different metabolic situation at the same percentage of maximum. This study helps to reduce sex bias in science, and future guidelines should consider establishing exercise prescription recommendations according to sex. <jats:italic><jats:bold>Clinical Trial:<\/jats:bold><\/jats:italic> NCT06104150.<\/jats:p>","DOI":"10.1123\/ijspp.2024-0079","type":"journal-article","created":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T20:13:30Z","timestamp":1730146410000},"page":"30-36","source":"Crossref","is-referenced-by-count":17,"title":["Greater Relative First and Second Lactate Thresholds in Females Compared With Males: Consideration for Exercise Prescription"],"prefix":"10.1123","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5375-5931","authenticated-orcid":true,"given":"Jos\u00e9 Antonio","family":"Ben\u00edtez-Mu\u00f1oz","sequence":"first","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science (INEF), Universidad Polit\u00e9cnica de Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3217-7786","authenticated-orcid":true,"given":"Miguel \u00c1ngel","family":"Rojo-Tirado","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science (INEF), Universidad Polit\u00e9cnica de Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1631-8182","authenticated-orcid":true,"given":"Pedro Jos\u00e9","family":"Benito Peinado","sequence":"additional","affiliation":[{"name":"LFE Research Group, Department of Health and Human Performance, Faculty of Physical Activity and Sport Science (INEF), Universidad Polit\u00e9cnica de Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6460-6453","authenticated-orcid":true,"given":"Juan M.","family":"Murias","sequence":"additional","affiliation":[{"name":"College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7578-241X","authenticated-orcid":true,"given":"Domingo","family":"Gonz\u00e1lez-Lamu\u00f1o","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgery Sciences, School of Medicine-IDIVAL, Universidad de Cantabria-Hospital M. 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