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Our purpose was to quantify bilateral vastus lateralis (VL) fascicle length change and the association thereof with gait biomechanics during weight acceptance in individuals with ACLR. The authors hypothesized that ACLR limbs would exhibit more fascicle lengthening than contralateral limbs. The authors also hypothesized that ACLR limbs would exhibit positive correlations between VL fascicle lengthening and knee joint biomechanics during weight acceptance in walking. The authors quantified VL contractile dynamics via cine B-mode ultrasound imaging in 18 individuals with ACLR walking on an instrumented treadmill. In partial support of our hypothesis, ACLR limb VL fascicles activated without length change on average during weight acceptance while fascicle length on the contralateral limb decreased on average. The authors found a positive association between fascicle lengthening and increase in knee extensor moments in both limbs. Our results suggest that examining quadriceps muscle dynamics may elucidate underlying mechanisms relevant to osteoarthritis.<\/jats:p>","DOI":"10.1123\/jab.2021-0381","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T11:59:48Z","timestamp":1661428788000},"page":"328-335","source":"Crossref","is-referenced-by-count":5,"title":["Quadriceps Muscle Action and Association With Knee Joint Biomechanics in Individuals with Anterior Cruciate Ligament Reconstruction"],"prefix":"10.1123","volume":"38","author":[{"given":"Amanda E.","family":"Munsch","sequence":"first","affiliation":[{"name":"Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Evans-Pickett","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science, UNC Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hope","family":"Davis-Wilson","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science, UNC Chapel Hill, Chapel Hill, NC, USA"},{"name":"Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Pietrosimone","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science, UNC Chapel Hill, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason R.","family":"Franz","sequence":"additional","affiliation":[{"name":"Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"100","reference":[{"issue":"5","key":"r1","series-title":"Curr Opin Rheumatol","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1097\/01.bor.0000240365.16842.4e","article-title":"The role of ambulatory mechanics in the initiation and progression of knee osteoarthritis","volume":"18","author":"Andriacchi TP","year":"2006","unstructured":"Andriacchi TP, Mundermann A. 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