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We aimed to examine associations between physical activity and SEWB, and cultural engagement and community connection among NextGen participants. <jats:italic><jats:bold>Methods<\/jats:bold>:<\/jats:italic> Prior to recruiting participants, partnerships and relationships were developed with Aboriginal community organizations. Participant recruitment and self-reported data collection through questionnaires using established tools were led by Aboriginal youth peer researchers. Logistic regression estimated odds ratios for engaging in higher levels of physical activity (3\u20137\u00a0d vs 0\u20132\u00a0d) according to SEWB, culture, and community factors; models were adjusted for sex, age, and state\/territory. <jats:italic><jats:bold>Results<\/jats:bold>:<\/jats:italic> Of 1154 adolescents, 517 (45%) engaged in 3 to 7\u00a0days of physical activity. Factors associated with higher odds of physical activity were having good to excellent self-rated health; higher resilience; a lower risk Strengths and Difficulties Questionnaire score; regular community group\/club participation, team sport, individual sport, or church\/religious activities in the past 12\u00a0months; and perception of activities for young people to do in their community. <jats:italic><jats:bold>Conclusion<\/jats:bold>:<\/jats:italic> Physical activity participation was favorably associated with a holistic range of measures of adolescent health and well-being. These findings provide valuable insights for Aboriginal adolescent program and policy design and delivery. The follow-up of participants in this cohort study will allow for examination of causal associations.<\/jats:p>","DOI":"10.1123\/jpah.2024-0669","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T18:35:29Z","timestamp":1742322929000},"page":"737-748","source":"Crossref","is-referenced-by-count":2,"title":["Aboriginal Adolescent Physical Activity, Social and Emotional Well-Being, Culture, and Community Activities: The Next Generation Study in Australia"],"prefix":"10.1123","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2967-7977","authenticated-orcid":true,"given":"Rona","family":"Macniven","sequence":"first","affiliation":[{"name":"UNSW Sydney, School of Population Health, UNSW Faculty of Medicine & Health, Kensington, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1430-0480","authenticated-orcid":true,"given":"Chris","family":"McKay","sequence":"additional","affiliation":[{"name":"Center for Public Health Data and Policy, National Center for Epidemiology and Population Health, College of Health & Medicine, Australian National University, Canberra, ACT, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2099-0032","authenticated-orcid":true,"given":"Robyn","family":"Williams","sequence":"additional","affiliation":[{"name":"Curtin Medical School, Faculty of Health Sciences, Curtin University, Perth, WA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine","family":"Eades","sequence":"additional","affiliation":[{"name":"Office of the Chief Executive, East Metropolitan Health Service, Perth, WA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katiska","family":"Davis","sequence":"additional","affiliation":[{"name":"Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Whitby","sequence":"additional","affiliation":[{"name":"Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0718-6368","authenticated-orcid":true,"given":"Grace","family":"Joshy","sequence":"additional","affiliation":[{"name":"Center for Public Health Data and Policy, National Center for Epidemiology and Population Health, College of Health & Medicine, Australian National University, Canberra, ACT, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3448-662X","authenticated-orcid":true,"given":"Rebecca","family":"Ivers","sequence":"additional","affiliation":[{"name":"UNSW Sydney, School of Population Health, UNSW Faculty of Medicine & Health, Kensington, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8629-3390","authenticated-orcid":true,"given":"Sandra","family":"Eades","sequence":"additional","affiliation":[{"name":"Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"100","reference":[{"key":"r1","series-title":"Working Together: Aboriginal and Torres Strait Islander Mental Health and Wellbeing Principles and Practice","author":"Dudgeon PM","year":"2014","unstructured":"Dudgeon PM, Milroy H, Walker R. 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