{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T17:51:03Z","timestamp":1782150663016,"version":"3.54.5"},"reference-count":66,"publisher":"Human Kinetics","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"\n \n Objective<\/jats:bold>\n :\n <\/jats:italic>\n We examined the moderating effect of moderate to vigorous physical activity (MVPA) and body mass index (BMI) on the association between sedentary behavior (SB) and cardiometabolic markers (CMM) in adolescents.\n \n Methods:<\/jats:bold>\n <\/jats:italic>\n In this 3-year longitudinal study (2014, 2015, and 2017), we collected and analyzed data from 136 adolescents (10\u201313\u00a0y) from Jo\u00e3o Pessoa, Para\u00edba, Brazil. We collected SB data using an ActiGraph GT3X+ accelerometer and calculated total sedentary time (in hours per day), also classifying participants into 2 exposure patterns: \u201cLow SB\u201d (\u22648\u00a0h\/d) and \u201cHigh SB\u201d (>8\u00a0h\/d). We evaluated CMM including: glucose, total cholesterol (TC), triglycerides (TG), high-density (HDL-C) and low-density lipoprotein cholesterol non-HDL-C, TC\/HDL-C, TG\/HDL-C, BMI, waist circumference, and systolic and diastolic blood pressure. We applied Generalized Estimating Equations to test whether time spent in MVPA and BMI moderated associations between SB and CMM.\n \n Results:<\/jats:bold>\n <\/jats:italic>\n The Generalized Estimating Equation identified significant interactions between SB and MVPA, as well as between SB and BMI, for several CMM (\n P<\/jats:italic>\n \u2009<\u2009.05). Among adolescents with low SB exposure (\u22648\u00a0h\/d), those who accumulated more MVPA (>50\u00a0min\/d) showed more favorable lipid profiles, including TC, LDL-C, non-HDL-C, and TC\/HDL-C ratio. The combination of high SB exposure (>8\u00a0h\/d) and excess weight was associated with less favorable TG, TC\/HDL-C, TG\/HDL-C, HDL-C, waist circumference, and systolic blood pressure values. Even under low SB exposure, excess weight corresponded to less favorable TC\/HDL-C, TG\/HDL-C, HDL-C, and waist circumference levels.\n \n Conclusion:<\/jats:bold>\n <\/jats:italic>\n MVPA moderated associations with CMM only at low sedentary exposure, whereas excess body weight amplified adverse associations across multiple cardiometabolic outcomes during adolescence.\n <\/jats:p>","DOI":"10.1123\/jpah.2025-0492","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T18:49:48Z","timestamp":1772650188000},"page":"1030-1040","source":"Crossref","is-referenced-by-count":0,"title":["Moderating Effect of Physical Activity and Body Mass Index on the Relationship Between Sedentary Behavior and Cardiometabolic Markers in Adolescents: A Longitudinal Analysis"],"prefix":"10.1123","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3606-2396","authenticated-orcid":true,"given":"Gerfeson","family":"Mendon\u00e7a","sequence":"first","affiliation":[{"name":"Epidemiology Studies and Research Group, GEPEAF, Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Alagoas State Department of Education, SEDUC, Macei\u00f3, AL, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5976-7287","authenticated-orcid":true,"given":"Arthur Oliveira","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Epidemiology Studies and Research Group, GEPEAF, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5248-0059","authenticated-orcid":true,"given":"Eduarda Cristina da Costa","family":"Silva","sequence":"additional","affiliation":[{"name":"Epidemiology Studies and Research Group, GEPEAF, Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Physical Education Associate Graduate Program, University of Pernambuco and Federal University of Para\u00edba\u2014PAPGEF UPE\/UFPB, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3737-5557","authenticated-orcid":true,"given":"Jos\u00e9 Jean","family":"Toscano","sequence":"additional","affiliation":[{"name":"Physical Education Course, Federal University of Alagoas\u2014UFAL, Macei\u00f3, AL, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6731-3955","authenticated-orcid":true,"given":"Tayse Guedes","family":"Cabral","sequence":"additional","affiliation":[{"name":"Epidemiology Studies and Research Group, GEPEAF, Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Physical Education Associate Graduate Program, University of Pernambuco and Federal University of Para\u00edba\u2014PAPGEF UPE\/UFPB, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5854-7020","authenticated-orcid":true,"given":"Juliana Maria da Penha Freire","family":"Silva","sequence":"additional","affiliation":[{"name":"Epidemiology Studies and Research Group, GEPEAF, Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Physical Education Associate Graduate Program, University of Pernambuco and Federal University of Para\u00edba\u2014PAPGEF UPE\/UFPB, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1082-6098","authenticated-orcid":true,"given":"Jos\u00e9 Cazuza de","family":"Farias J\u00fanior","sequence":"additional","affiliation":[{"name":"Epidemiology Studies and Research Group, GEPEAF, Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Physical Education Associate Graduate Program, University of Pernambuco and Federal University of Para\u00edba\u2014PAPGEF UPE\/UFPB, Jo\u00e3o Pessoa, PB, Brazil"},{"name":"Federal University of Para\u00edba\u2014UFPB, Jo\u00e3o Pessoa, PB, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"100","reference":[{"issue":"1","key":"r1","series-title":"Obes Rev","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/obr.12758","article-title":"The prospective association between objectively measured sedentary time, moderate\u2010to\u2010vigorous physical activity and cardiometabolic risk factors in youth: a systematic review and meta\u2010analysis","volume":"20","author":"Skrede T","year":"2019","unstructured":"Skrede T, Steene\u2010Johannessen J, Anderssen SA, Resaland GK, Ekelund U. The prospective association between objectively measured sedentary time, moderate\u2010to\u2010vigorous physical activity and cardiometabolic risk factors in youth: a systematic review and meta\u2010analysis. Obes Rev. 2019;20(1):55\u201374. doi:10.1111\/obr.12758"},{"key":"r2","series-title":"Front Public Health","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1412389","article-title":"Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review","volume":"12","author":"Wang K","year":"2024","unstructured":"Wang K, Li Y, Liu H, Zhang T, Luo J. Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review. Front Public Health. 2024;12:1412389. doi:10.3389\/fpubh.2024.1412389"},{"issue":"16","key":"r3","series-title":"J Am Med Assoc","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1001\/jama.2019.3636","article-title":"Trends in sedentary behavior among the US population, 2001\u20132016","volume":"321","author":"Yang L","year":"2019","unstructured":"Yang L, Cao C, Kantor ED, et\u00a0al. Trends in sedentary behavior among the US population, 2001\u20132016. J Am Med Assoc. 2019;321(16):1587\u20131597. doi:10.1001\/jama.2019.3636"},{"key":"r4","series-title":"Children","doi-asserted-by":"publisher","DOI":"10.3390\/children12040513","article-title":"Exploring the acute effects of sedentary behaviors on cardiometabolic risk in Hispanic adolescents with obesity: a randomized crossover study","volume":"12","author":"Soltero EG","year":"2025","unstructured":"Soltero EG, Salim O, Mirabile Y, Musaad SM. Exploring the acute effects of sedentary behaviors on cardiometabolic risk in Hispanic adolescents with obesity: a randomized crossover study. Children. 2025;12:513. doi:10.3390\/children12040513"},{"issue":"4","key":"r5","series-title":"Obes Rev","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1111\/obr.12371","article-title":"Objectively measured sedentary behaviour and health and development in children and adolescents: systematic review and meta\u2010analysis","volume":"17","author":"Cliff DP","year":"2016","unstructured":"Cliff DP, Hesketh KD, Vella SA, et\u00a0al. Objectively measured sedentary behaviour and health and development in children and adolescents: systematic review and meta\u2010analysis. Obes Rev. 2016;17(4):330\u2013344. doi:10.1111\/obr.12371"},{"key":"r6","series-title":"Pediatr Exerc Sci","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1123\/pes.2023-0202","article-title":"Sedentary behavior and cardiometabolic markers in adolescents: a 4-year longitudinal study","volume":"37","author":"Mendon\u00e7a G","year":"2024","unstructured":"Mendon\u00e7a G, Barbosa AO, Moura IRD, et\u00a0al. Sedentary behavior and cardiometabolic markers in adolescents: a 4-year longitudinal study. Pediatr Exerc Sci. 2024;37:154\u2013163. doi:10.1123\/pes.2023-0202"},{"key":"r7","series-title":"J Am Heart Assoc","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.031837","article-title":"Accumulating sedentary time and physical activity from childhood to adolescence and cardiac function in adolescence","volume":"13","author":"Haapala EA","year":"2024","unstructured":"Haapala EA, Lepp\u00e4nen MH, Lee E, et\u00a0al. Accumulating sedentary time and physical activity from childhood to adolescence and cardiac function in adolescence. J Am Heart Assoc. 2024;13:e031837. doi:10.1161\/JAHA.123.031837"},{"issue":"1","key":"r8","series-title":"BMC Public Health","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-200","article-title":"The association between accelerometer-measured patterns of sedentary time and health risk in children and youth: results from the Canadian health measures survey","volume":"13","author":"Colley RC","year":"2013","unstructured":"Colley RC, Garriguet D, Janssen I, et\u00a0al. The association between accelerometer-measured patterns of sedentary time and health risk in children and youth: results from the Canadian health measures survey. BMC Public Health. 2013;13(1):200. doi:10.1186\/1471-2458-13-200"},{"issue":"6","key":"r9","series-title":"Am J Prev Med","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1016\/j.amepre.2017.07.009","article-title":"Sedentary time, physical activity, and adiposity: cross-sectional and longitudinal associations in CARDIA","volume":"53","author":"Gibbs BB","year":"2017","unstructured":"Gibbs BB, Gabriel KP, Carnethon MR, et\u00a0al. Sedentary time, physical activity, and adiposity: cross-sectional and longitudinal associations in CARDIA. Am J Prev Med. 2017;53(6):764\u2013771. doi:10.1016\/j.amepre.2017.07.009"},{"key":"r10","series-title":"Int J Behav Nutr Phys Act","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-022-01375-0","article-title":"Sedentary patterns and cardiometabolic risk factors in Mexican children and adolescents: analysis of longitudinal data","volume":"19","author":"Aljahdali AA","year":"2022","unstructured":"Aljahdali AA, Baylin A, Ruiz-Narvaez EA, et\u00a0al. Sedentary patterns and cardiometabolic risk factors in Mexican children and adolescents: analysis of longitudinal data. Int J Behav Nutr Phys Act. 2022;19:143. doi:10.1186\/s12966-022-01375-0"},{"issue":"3","key":"r11","series-title":"Revis Espa\u00f1ola Cardiol","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/S0300-8932(10)70083-X.","article-title":"Sedentary behaviour and biomarkers of cardiometabolic health risk in adolescents: an emerging scientific and public health issue","volume":"63","author":"Healy GN","year":"2010","unstructured":"Healy GN, Owen N. Sedentary behaviour and biomarkers of cardiometabolic health risk in adolescents: an emerging scientific and public health issue. Revis Espa\u00f1ola Cardiol (English Edition). 2010;63(3):261\u2013264. doi:10.1016\/S0300-8932(10)70083-X."},{"issue":"8","key":"r12","series-title":"Scand J Med Sci Sports","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1111\/sms.14365","article-title":"Associations of accelerometer\u2010based sedentary time, light physical activity and moderate\u2010to\u2010vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status","volume":"33","author":"Agbaje AO","year":"2023","unstructured":"Agbaje AO. Associations of accelerometer\u2010based sedentary time, light physical activity and moderate\u2010to\u2010vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status. Scand J Med Sci Sports. 2023;33(8):1399\u20131411. doi:10.1111\/sms.14365"},{"issue":"1","key":"r13","series-title":"Can J Diabetes","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jcjd.2013.08.266.","article-title":"Sedentary behaviour as an emerging risk factor for cardiometabolic diseases in children and youth","volume":"38","author":"Saunders TJ","year":"2014","unstructured":"Saunders TJ, Chaput J-P, Tremblay MS. Sedentary behaviour as an emerging risk factor for cardiometabolic diseases in children and youth. Can J Diabetes 2014;38(1):53\u201361. doi:10.1016\/j.jcjd.2013.08.266."},{"key":"r14","series-title":"WHO Guidelines on Physical Activity and Sedentary Behaviour","year":"2020","unstructured":"World Health Organization. WHO Guidelines on Physical Activity and Sedentary Behaviour. 2020."},{"issue":"7","key":"r15","series-title":"J Clin Endocrinol Metab","doi-asserted-by":"publisher","first-page":"e1494","DOI":"10.1210\/clinem\/dgad688","article-title":"Associations of sedentary time and physical activity from childhood with lipids: a 13-year mediation and temporal study","volume":"109","author":"Agbaje AO","year":"2024","unstructured":"Agbaje AO. Associations of sedentary time and physical activity from childhood with lipids: a 13-year mediation and temporal study. J Clin Endocrinol Metab. 2024;109(7):e1494\u2013e1505. doi:10.1210\/clinem\/dgad688"},{"key":"r16","series-title":"Revis Brasil Ci\u00eancias Esporte","article-title":"Time and bouts of sedentary behavior and cardiometabolic markers in adolescents","volume":"42","author":"Prazeres Filho A","year":"2020","unstructured":"Prazeres Filho A, Barbosa AO, Farias J\u00fanior JC. Time and bouts of sedentary behavior and cardiometabolic markers in adolescents. Revis Brasil Ci\u00eancias Esporte. 2020;42:e2028."},{"key":"r17","article-title":"Brazil economic classification criterion [Internet]","year":"2009","unstructured":"ABEP\u2014Brazilian Association of Research Companies. Brazil economic classification criterion [Internet]. 2009. http:\/\/www.abep.org\/new\/codigosCondutas.aspx"},{"key":"r18","series-title":"Applied Body Composition Assessment","author":"Heyward VH","year":"2004","unstructured":"Heyward VH, Stolarczyk LM. Applied Body Composition Assessment. Human Kinetics; 2004."},{"issue":"6","key":"r19","series-title":"Clin Chem","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge\u2014PubMed","volume":"18","author":"Friedewald WT","year":"1972","unstructured":"Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge\u2014PubMed. Clin Chem. 1972;18(6):499\u2013502. doi:10.1093\/clinchem\/18.6.499"},{"key":"r20","series-title":"Eur J Sport Sci","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1080\/17461391.2022.2098057","article-title":"Longitudinal association between moderate to vigorous physical activity and lipid profile indicators in adolescents: physical activity and lipid profile in adolescents","volume":"23","author":"Barbosa AO","year":"2022","unstructured":"Barbosa AO, Penha JMFS, Silva DJ, et\u00a0al. Longitudinal association between moderate to vigorous physical activity and lipid profile indicators in adolescents: physical activity and lipid profile in adolescents. Eur J Sport Sci. 2022;23:1405\u20131414. doi:10.1080\/17461391.2022.2098057"},{"issue":"14","key":"r21","series-title":"J Sports Sci","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1080\/02640410802334196","article-title":"Calibration of two objective measures of physical activity for children","volume":"26","author":"Evenson KR","year":"2008","unstructured":"Evenson KR, Catellier DJ, Gill K, Ondrak KS, McMurray RG. Calibration of two objective measures of physical activity for children. J Sports Sci. 2008;26(14):1557\u20131565. doi:10.1080\/02640410802334196"},{"issue":"7","key":"r22","series-title":"Int J Obes","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1038\/ijo.2017.69","article-title":"Longitudinal study of the associations between change in sedentary behavior and change in adiposity during childhood and adolescence: Gateshead millennium study","volume":"41","author":"Mann KD","year":"2017","unstructured":"Mann KD, Howe LD, Basterfield L, et\u00a0al. Longitudinal study of the associations between change in sedentary behavior and change in adiposity during childhood and adolescence: Gateshead millennium study. Int J Obes. 2017;41(7):1042\u20131047. doi:10.1038\/ijo.2017.69"},{"issue":"3","key":"r23","series-title":"Biometrika","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1093\/biomet\/63.3.581","article-title":"Inference and missing data","volume":"63","author":"Rubin DB","year":"1976","unstructured":"Rubin DB. Inference and missing data. Biometrika. 1976;63(3):581\u2013592. doi:10.1093\/biomet\/63.3.581"},{"issue":"24","key":"r24","series-title":"Stat Med","doi-asserted-by":"publisher","first-page":"4279","DOI":"10.1002\/sim.2673","article-title":"The design of simulation studies in medical statistics","volume":"25","author":"Burton A","year":"2006","unstructured":"Burton A, Altman DG, Royston P, Holder RL. The design of simulation studies in medical statistics. Stat Med. 2006;25(24):4279\u20134292. doi:10.1002\/sim.2673"},{"issue":"8","key":"r25","series-title":"Transl Behav Med","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1093\/tbm\/ibab046","article-title":"Sedentary behavior moderates the relationship between physical activity and cardiometabolic risk in young Latino children","volume":"11","author":"Malik JA","year":"2021","unstructured":"Malik JA, Coto J, Pulgaron ER, et\u00a0al. Sedentary behavior moderates the relationship between physical activity and cardiometabolic risk in young Latino children. Transl Behav Med. 2021;11(8):1517\u20131526. doi:10.1093\/tbm\/ibab046"},{"issue":"7","key":"r26","series-title":"J Am Med Assoc","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1001\/jama.2012.156","article-title":"Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents","volume":"307","author":"Ekelund U","year":"2012","unstructured":"Ekelund U, Luan J, Sherar LB, Esliger DW, Griew P, Cooper A. Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents. J Am Med Assoc. 2012;307(7):704\u2013712. doi:10.1001\/jama.2012.156"},{"key":"r27","series-title":"Exerc Sport Sci Rev","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1097\/00003677-200410000-00007","article-title":"Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation","volume":"32","author":"Hamilton MT","year":"2004","unstructured":"Hamilton MT, Hamilton DG, Zderic TW. Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation. Exerc Sport Sci Rev. 2004;32:161\u2013166. doi:10.1097\/00003677-200410000-00007"},{"issue":"8","key":"r28","series-title":"Nat Rev Endocrinol","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nrendo.2012.49","article-title":"Muscles, exercise and obesity: skeletal muscle as a secretory organ","volume":"8","author":"Pedersen BK","year":"2012","unstructured":"Pedersen BK, Febbraio MA. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol. 2012;8(8):457\u2013465. doi:10.1038\/nrendo.2012.49"},{"issue":"1","key":"r29","series-title":"Scand J Med Sci Sports","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1111\/sms.13315","article-title":"Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children: the PANIC study","volume":"29","author":"V\u00e4ist\u00f6 J","year":"2019","unstructured":"V\u00e4ist\u00f6 J, Haapala EA, Viitasalo A, et\u00a0al. Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children: the PANIC study. Scand J Med Sci Sports. 2019;29(1):113\u2013123. doi:10.1111\/sms.13315"},{"key":"r30","series-title":"Arq Bras Cardiol","doi-asserted-by":"publisher","first-page":"238","DOI":"10.5935\/abc.20140104","article-title":"Elevated blood pressure and obesity in childhood: a cross-sectional valuation of 4,609 schoolchildren","volume":"103","author":"Rosaneli CF","year":"2014","unstructured":"Rosaneli CF, Baena CP, Auler F, et\u00a0al. Elevated blood pressure and obesity in childhood: a cross-sectional valuation of 4,609 schoolchildren. Arq Bras Cardiol. 2014;103:238\u2013244. doi:10.5935\/abc.20140104"},{"issue":"24","key":"r31","series-title":"Int J Environ Res Public Health","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17249526","article-title":"Adiposity and high blood pressure during childhood: a prospective analysis of the role of physical activity intensity and sedentary time in the GECKO Drenthe cohort","volume":"17","author":"Wiersma R","year":"2020","unstructured":"Wiersma R, Hartman E, Boezen HM, Corpeleijn E. Adiposity and high blood pressure during childhood: a prospective analysis of the role of physical activity intensity and sedentary time in the GECKO Drenthe cohort. Int J Environ Res Public Health. 2020;17(24):9526. doi:10.3390\/ijerph17249526"},{"issue":"268","key":"r32","series-title":"J Nursing Edi\u00e7\u00e3o Brasil","doi-asserted-by":"publisher","first-page":"4608","DOI":"10.36489\/nursing.2020v23i268p4608-4623","article-title":"Prevalence of systemic arterial hypertension in children of the state public network of Carmel of Cajuru-MG","volume":"23","author":"Silva VA","year":"2020","unstructured":"Silva VA, Rabelo TN, Rezende FM, Quadros KAN, Santos RC, Andrade SN. Prevalence of systemic arterial hypertension in children of the state public network of Carmel of Cajuru-MG. J Nursing Edi\u00e7\u00e3o Brasil. 2020;23(268):4608\u20134623. doi:10.36489\/nursing.2020v23i268p4608-4623"},{"issue":"4","key":"r33","series-title":"J Ci\u00eancia Sa\u00fade Coletiva","doi-asserted-by":"publisher","DOI":"10.1590\/1413-81232024294.17082022","article-title":"Association between sedentary behavior, diet and nutritional status in adolescents: baseline results from the LONCAAFS study","volume":"29","author":"Arruda Neta ACP","year":"2024","unstructured":"Arruda Neta ACP, Farias Junior JC, Ferreira FELL, Aznar LAM, Marchioni DML. Association between sedentary behavior, diet and nutritional status in adolescents: baseline results from the LONCAAFS study. J Ci\u00eancia Sa\u00fade Coletiva. 2024;29(4):e17082022. doi:10.1590\/1413-81232024294.17082022"},{"issue":"1","key":"r1","series-title":"Obes Rev","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/obr.12758","article-title":"The prospective association between objectively measured sedentary time, moderate\u2010to\u2010vigorous physical activity and cardiometabolic risk factors in youth: a systematic review and meta\u2010analysis","volume":"20","author":"Skrede T","year":"2019","unstructured":"Skrede T, Steene\u2010Johannessen J, Anderssen SA, Resaland GK, Ekelund U. The prospective association between objectively measured sedentary time, moderate\u2010to\u2010vigorous physical activity and cardiometabolic risk factors in youth: a systematic review and meta\u2010analysis. Obes Rev. 2019;20(1):55\u201374. doi:10.1111\/obr.12758"},{"key":"r2","series-title":"Front Public Health","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1412389","article-title":"Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review","volume":"12","author":"Wang K","year":"2024","unstructured":"Wang K, Li Y, Liu H, Zhang T, Luo J. Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review. Front Public Health. 2024;12:1412389. doi:10.3389\/fpubh.2024.1412389"},{"issue":"16","key":"r3","series-title":"J Am Med Assoc","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1001\/jama.2019.3636","article-title":"Trends in sedentary behavior among the US population, 2001\u20132016","volume":"321","author":"Yang L","year":"2019","unstructured":"Yang L, Cao C, Kantor ED, et\u00a0al. Trends in sedentary behavior among the US population, 2001\u20132016. J Am Med Assoc. 2019;321(16):1587\u20131597. doi:10.1001\/jama.2019.3636"},{"key":"r4","series-title":"Children","doi-asserted-by":"publisher","DOI":"10.3390\/children12040513","article-title":"Exploring the acute effects of sedentary behaviors on cardiometabolic risk in Hispanic adolescents with obesity: a randomized crossover study","volume":"12","author":"Soltero EG","year":"2025","unstructured":"Soltero EG, Salim O, Mirabile Y, Musaad SM. Exploring the acute effects of sedentary behaviors on cardiometabolic risk in Hispanic adolescents with obesity: a randomized crossover study. Children. 2025;12:513. doi:10.3390\/children12040513"},{"issue":"4","key":"r5","series-title":"Obes Rev","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1111\/obr.12371","article-title":"Objectively measured sedentary behaviour and health and development in children and adolescents: systematic review and meta\u2010analysis","volume":"17","author":"Cliff DP","year":"2016","unstructured":"Cliff DP, Hesketh KD, Vella SA, et\u00a0al. Objectively measured sedentary behaviour and health and development in children and adolescents: systematic review and meta\u2010analysis. Obes Rev. 2016;17(4):330\u2013344. doi:10.1111\/obr.12371"},{"key":"r6","series-title":"Pediatr Exerc Sci","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1123\/pes.2023-0202","article-title":"Sedentary behavior and cardiometabolic markers in adolescents: a 4-year longitudinal study","volume":"37","author":"Mendon\u00e7a G","year":"2024","unstructured":"Mendon\u00e7a G, Barbosa AO, Moura IRD, et\u00a0al. Sedentary behavior and cardiometabolic markers in adolescents: a 4-year longitudinal study. Pediatr Exerc Sci. 2024;37:154\u2013163. doi:10.1123\/pes.2023-0202"},{"key":"r7","series-title":"J Am Heart Assoc","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.031837","article-title":"Accumulating sedentary time and physical activity from childhood to adolescence and cardiac function in adolescence","volume":"13","author":"Haapala EA","year":"2024","unstructured":"Haapala EA, Lepp\u00e4nen MH, Lee E, et\u00a0al. Accumulating sedentary time and physical activity from childhood to adolescence and cardiac function in adolescence. J Am Heart Assoc. 2024;13:e031837. doi:10.1161\/JAHA.123.031837"},{"issue":"1","key":"r8","series-title":"BMC Public Health","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-13-200","article-title":"The association between accelerometer-measured patterns of sedentary time and health risk in children and youth: results from the Canadian health measures survey","volume":"13","author":"Colley RC","year":"2013","unstructured":"Colley RC, Garriguet D, Janssen I, et\u00a0al. The association between accelerometer-measured patterns of sedentary time and health risk in children and youth: results from the Canadian health measures survey. BMC Public Health. 2013;13(1):200. doi:10.1186\/1471-2458-13-200"},{"issue":"6","key":"r9","series-title":"Am J Prev Med","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1016\/j.amepre.2017.07.009","article-title":"Sedentary time, physical activity, and adiposity: cross-sectional and longitudinal associations in CARDIA","volume":"53","author":"Gibbs BB","year":"2017","unstructured":"Gibbs BB, Gabriel KP, Carnethon MR, et\u00a0al. Sedentary time, physical activity, and adiposity: cross-sectional and longitudinal associations in CARDIA. Am J Prev Med. 2017;53(6):764\u2013771. doi:10.1016\/j.amepre.2017.07.009"},{"key":"r10","series-title":"Int J Behav Nutr Phys Act","doi-asserted-by":"publisher","DOI":"10.1186\/s12966-022-01375-0","article-title":"Sedentary patterns and cardiometabolic risk factors in Mexican children and adolescents: analysis of longitudinal data","volume":"19","author":"Aljahdali AA","year":"2022","unstructured":"Aljahdali AA, Baylin A, Ruiz-Narvaez EA, et\u00a0al. Sedentary patterns and cardiometabolic risk factors in Mexican children and adolescents: analysis of longitudinal data. Int J Behav Nutr Phys Act. 2022;19:143. doi:10.1186\/s12966-022-01375-0"},{"issue":"3","key":"r11","series-title":"Revis Espa\u00f1ola Cardiol","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/S0300-8932(10)70083-X.","article-title":"Sedentary behaviour and biomarkers of cardiometabolic health risk in adolescents: an emerging scientific and public health issue","volume":"63","author":"Healy GN","year":"2010","unstructured":"Healy GN, Owen N. Sedentary behaviour and biomarkers of cardiometabolic health risk in adolescents: an emerging scientific and public health issue. Revis Espa\u00f1ola Cardiol (English Edition). 2010;63(3):261\u2013264. doi:10.1016\/S0300-8932(10)70083-X."},{"issue":"8","key":"r12","series-title":"Scand J Med Sci Sports","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1111\/sms.14365","article-title":"Associations of accelerometer\u2010based sedentary time, light physical activity and moderate\u2010to\u2010vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status","volume":"33","author":"Agbaje AO","year":"2023","unstructured":"Agbaje AO. Associations of accelerometer\u2010based sedentary time, light physical activity and moderate\u2010to\u2010vigorous physical activity with resting cardiac structure and function in adolescents according to sex, fat mass, lean mass, BMI, and hypertensive status. Scand J Med Sci Sports. 2023;33(8):1399\u20131411. doi:10.1111\/sms.14365"},{"issue":"1","key":"r13","series-title":"Can J Diabetes","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.jcjd.2013.08.266.","article-title":"Sedentary behaviour as an emerging risk factor for cardiometabolic diseases in children and youth","volume":"38","author":"Saunders TJ","year":"2014","unstructured":"Saunders TJ, Chaput J-P, Tremblay MS. Sedentary behaviour as an emerging risk factor for cardiometabolic diseases in children and youth. Can J Diabetes 2014;38(1):53\u201361. doi:10.1016\/j.jcjd.2013.08.266."},{"key":"r14","series-title":"WHO Guidelines on Physical Activity and Sedentary Behaviour","year":"2020","unstructured":"World Health Organization. WHO Guidelines on Physical Activity and Sedentary Behaviour. 2020."},{"issue":"7","key":"r15","series-title":"J Clin Endocrinol Metab","doi-asserted-by":"publisher","first-page":"e1494","DOI":"10.1210\/clinem\/dgad688","article-title":"Associations of sedentary time and physical activity from childhood with lipids: a 13-year mediation and temporal study","volume":"109","author":"Agbaje AO","year":"2024","unstructured":"Agbaje AO. Associations of sedentary time and physical activity from childhood with lipids: a 13-year mediation and temporal study. J Clin Endocrinol Metab. 2024;109(7):e1494\u2013e1505. doi:10.1210\/clinem\/dgad688"},{"key":"r16","series-title":"Revis Brasil Ci\u00eancias Esporte","article-title":"Time and bouts of sedentary behavior and cardiometabolic markers in adolescents","volume":"42","author":"Prazeres Filho A","year":"2020","unstructured":"Prazeres Filho A, Barbosa AO, Farias J\u00fanior JC. Time and bouts of sedentary behavior and cardiometabolic markers in adolescents. Revis Brasil Ci\u00eancias Esporte. 2020;42:e2028."},{"key":"r17","article-title":"Brazil economic classification criterion [Internet]","year":"2009","unstructured":"ABEP\u2014Brazilian Association of Research Companies. Brazil economic classification criterion [Internet]. 2009. http:\/\/www.abep.org\/new\/codigosCondutas.aspx"},{"key":"r18","series-title":"Applied Body Composition Assessment","author":"Heyward VH","year":"2004","unstructured":"Heyward VH, Stolarczyk LM. Applied Body Composition Assessment. Human Kinetics; 2004."},{"issue":"6","key":"r19","series-title":"Clin Chem","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","article-title":"Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge\u2014PubMed","volume":"18","author":"Friedewald WT","year":"1972","unstructured":"Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge\u2014PubMed. Clin Chem. 1972;18(6):499\u2013502. doi:10.1093\/clinchem\/18.6.499"},{"key":"r20","series-title":"Eur J Sport Sci","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1080\/17461391.2022.2098057","article-title":"Longitudinal association between moderate to vigorous physical activity and lipid profile indicators in adolescents: physical activity and lipid profile in adolescents","volume":"23","author":"Barbosa AO","year":"2022","unstructured":"Barbosa AO, Penha JMFS, Silva DJ, et\u00a0al. Longitudinal association between moderate to vigorous physical activity and lipid profile indicators in adolescents: physical activity and lipid profile in adolescents. Eur J Sport Sci. 2022;23:1405\u20131414. doi:10.1080\/17461391.2022.2098057"},{"issue":"14","key":"r21","series-title":"J Sports Sci","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1080\/02640410802334196","article-title":"Calibration of two objective measures of physical activity for children","volume":"26","author":"Evenson KR","year":"2008","unstructured":"Evenson KR, Catellier DJ, Gill K, Ondrak KS, McMurray RG. Calibration of two objective measures of physical activity for children. J Sports Sci. 2008;26(14):1557\u20131565. doi:10.1080\/02640410802334196"},{"issue":"7","key":"r22","series-title":"Int J Obes","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1038\/ijo.2017.69","article-title":"Longitudinal study of the associations between change in sedentary behavior and change in adiposity during childhood and adolescence: Gateshead millennium study","volume":"41","author":"Mann KD","year":"2017","unstructured":"Mann KD, Howe LD, Basterfield L, et\u00a0al. Longitudinal study of the associations between change in sedentary behavior and change in adiposity during childhood and adolescence: Gateshead millennium study. Int J Obes. 2017;41(7):1042\u20131047. doi:10.1038\/ijo.2017.69"},{"issue":"3","key":"r23","series-title":"Biometrika","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1093\/biomet\/63.3.581","article-title":"Inference and missing data","volume":"63","author":"Rubin DB","year":"1976","unstructured":"Rubin DB. Inference and missing data. Biometrika. 1976;63(3):581\u2013592. doi:10.1093\/biomet\/63.3.581"},{"issue":"24","key":"r24","series-title":"Stat Med","doi-asserted-by":"publisher","first-page":"4279","DOI":"10.1002\/sim.2673","article-title":"The design of simulation studies in medical statistics","volume":"25","author":"Burton A","year":"2006","unstructured":"Burton A, Altman DG, Royston P, Holder RL. The design of simulation studies in medical statistics. Stat Med. 2006;25(24):4279\u20134292. doi:10.1002\/sim.2673"},{"issue":"8","key":"r25","series-title":"Transl Behav Med","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1093\/tbm\/ibab046","article-title":"Sedentary behavior moderates the relationship between physical activity and cardiometabolic risk in young Latino children","volume":"11","author":"Malik JA","year":"2021","unstructured":"Malik JA, Coto J, Pulgaron ER, et\u00a0al. Sedentary behavior moderates the relationship between physical activity and cardiometabolic risk in young Latino children. Transl Behav Med. 2021;11(8):1517\u20131526. doi:10.1093\/tbm\/ibab046"},{"issue":"7","key":"r26","series-title":"J Am Med Assoc","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1001\/jama.2012.156","article-title":"Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents","volume":"307","author":"Ekelund U","year":"2012","unstructured":"Ekelund U, Luan J, Sherar LB, Esliger DW, Griew P, Cooper A. Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents. J Am Med Assoc. 2012;307(7):704\u2013712. doi:10.1001\/jama.2012.156"},{"key":"r27","series-title":"Exerc Sport Sci Rev","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1097\/00003677-200410000-00007","article-title":"Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation","volume":"32","author":"Hamilton MT","year":"2004","unstructured":"Hamilton MT, Hamilton DG, Zderic TW. Exercise physiology versus inactivity physiology: an essential concept for understanding lipoprotein lipase regulation. Exerc Sport Sci Rev. 2004;32:161\u2013166. doi:10.1097\/00003677-200410000-00007"},{"issue":"8","key":"r28","series-title":"Nat Rev Endocrinol","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nrendo.2012.49","article-title":"Muscles, exercise and obesity: skeletal muscle as a secretory organ","volume":"8","author":"Pedersen BK","year":"2012","unstructured":"Pedersen BK, Febbraio MA. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol. 2012;8(8):457\u2013465. doi:10.1038\/nrendo.2012.49"},{"issue":"1","key":"r29","series-title":"Scand J Med Sci Sports","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1111\/sms.13315","article-title":"Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children: the PANIC study","volume":"29","author":"V\u00e4ist\u00f6 J","year":"2019","unstructured":"V\u00e4ist\u00f6 J, Haapala EA, Viitasalo A, et\u00a0al. Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children: the PANIC study. Scand J Med Sci Sports. 2019;29(1):113\u2013123. doi:10.1111\/sms.13315"},{"key":"r30","series-title":"Arq Bras Cardiol","doi-asserted-by":"publisher","first-page":"238","DOI":"10.5935\/abc.20140104","article-title":"Elevated blood pressure and obesity in childhood: a cross-sectional valuation of 4,609 schoolchildren","volume":"103","author":"Rosaneli CF","year":"2014","unstructured":"Rosaneli CF, Baena CP, Auler F, et\u00a0al. Elevated blood pressure and obesity in childhood: a cross-sectional valuation of 4,609 schoolchildren. Arq Bras Cardiol. 2014;103:238\u2013244. doi:10.5935\/abc.20140104"},{"issue":"24","key":"r31","series-title":"Int J Environ Res Public Health","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17249526","article-title":"Adiposity and high blood pressure during childhood: a prospective analysis of the role of physical activity intensity and sedentary time in the GECKO Drenthe cohort","volume":"17","author":"Wiersma R","year":"2020","unstructured":"Wiersma R, Hartman E, Boezen HM, Corpeleijn E. Adiposity and high blood pressure during childhood: a prospective analysis of the role of physical activity intensity and sedentary time in the GECKO Drenthe cohort. Int J Environ Res Public Health. 2020;17(24):9526. doi:10.3390\/ijerph17249526"},{"issue":"268","key":"r32","series-title":"J Nursing Edi\u00e7\u00e3o Brasil","doi-asserted-by":"publisher","first-page":"4608","DOI":"10.36489\/nursing.2020v23i268p4608-4623","article-title":"Prevalence of systemic arterial hypertension in children of the state public network of Carmel of Cajuru-MG","volume":"23","author":"Silva VA","year":"2020","unstructured":"Silva VA, Rabelo TN, Rezende FM, Quadros KAN, Santos RC, Andrade SN. Prevalence of systemic arterial hypertension in children of the state public network of Carmel of Cajuru-MG. J Nursing Edi\u00e7\u00e3o Brasil. 2020;23(268):4608\u20134623. doi:10.36489\/nursing.2020v23i268p4608-4623"},{"issue":"4","key":"r33","series-title":"J Ci\u00eancia Sa\u00fade Coletiva","doi-asserted-by":"publisher","DOI":"10.1590\/1413-81232024294.17082022","article-title":"Association between sedentary behavior, diet and nutritional status in adolescents: baseline results from the LONCAAFS study","volume":"29","author":"Arruda Neta ACP","year":"2024","unstructured":"Arruda Neta ACP, Farias Junior JC, Ferreira FELL, Aznar LAM, Marchioni DML. Association between sedentary behavior, diet and nutritional status in adolescents: baseline results from the LONCAAFS study. J Ci\u00eancia Sa\u00fade Coletiva. 2024;29(4):e17082022. doi:10.1590\/1413-81232024294.17082022"}],"container-title":["Journal of Physical Activity and Health"],"original-title":[],"link":[{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/jpah\/23\/7\/article-p1030.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/jpah\/23\/7\/article-p1030.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/jpah\/23\/7\/article-p1030.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T17:33:41Z","timestamp":1782149621000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/jpah\/23\/7\/article-p1030.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":66,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.1123\/jpah.2025-0492","relation":{},"ISSN":["1543-3080","1543-5474"],"issn-type":[{"value":"1543-3080","type":"print"},{"value":"1543-5474","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]}}}