{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T03:27:13Z","timestamp":1782185233026,"version":"3.54.5"},"reference-count":0,"publisher":"Human Kinetics","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:sec sec-type=\"context\"><jats:title>Context:<\/jats:title><jats:p>Motoneuron-pool facilitation after cryotherapy may be mediated by stimulation of thermoreceptors surrounding a joint. It is unknown whether menthol counterirritants, which also stimulate thermoreceptors, have the same effect on motoneuron-pool excitability (MNPE).<\/jats:p><\/jats:sec><jats:sec sec-type=\"objective\"><jats:title>Objective:<\/jats:title><jats:p>To compare quadriceps MNPE after a menthol-counterirritant application to the anterior knee, a sham counterirritant application, and a control treatment in healthy subjects.<\/jats:p><\/jats:sec><jats:sec sec-type=\"design\"><jats:title>Design:<\/jats:title><jats:p>A blinded, randomized controlled laboratory study.<\/jats:p><\/jats:sec><jats:sec sec-type=\"setting\"><jats:title>Setting:<\/jats:title><jats:p>Laboratory.<\/jats:p><\/jats:sec><jats:sec sec-type=\"participants\"><jats:title>Participants:<\/jats:title><jats:p>Thirty healthy subjects (16 m, 14 f; 24.1 \u00b1 3.9 y, 170.6 \u00b1 11.4 cm, 72.1 \u00b1 15.6 kg) with no history of lower extremity surgery volunteered for this study.<\/jats:p><\/jats:sec><jats:sec sec-type=\"intervention\"><jats:title>Intervention:<\/jats:title><jats:p>Two milliliters of menthol or sham counterirritant was applied to the anterior knee; control subjects received no intervention.<\/jats:p><\/jats:sec><jats:sec sec-type=\"main outcome measures\"><jats:title>Main Outcome Measures:<\/jats:title><jats:p>The average vastus medialis normalized Hoffmann reflex (H<jats:sub>max<\/jats:sub>:M<jats:sub>max<\/jats:sub> ratio) was used to measure MNPE. Measurements were recorded at 5, 15, 25, and 35 minutes postintervention and compared with baseline measures.<\/jats:p><\/jats:sec><jats:sec sec-type=\"results\"><jats:title>Results:<\/jats:title><jats:p>H<jats:sub>max<\/jats:sub>:M<jats:sub>max<\/jats:sub> ratios for all groups significantly decreased over time (<jats:italic>F<\/jats:italic><jats:sub>4,108<\/jats:sub> = 10.52, <jats:italic>P<\/jats:italic> &lt; .001; menthol: baseline = .32 \u00b1 .20, 5 min = .29 \u00b1 .18, 15 min = .27 \u00b1 .18, 25 min = .28 \u00b1 .19, 35 min = .27 \u00b1 .18; sham: baseline = .46 \u00b1 .26, 5 min = .36 \u00b1 .20, 15 min = .35 \u00b1 .19, 25 min = .35 \u00b1 .20, 35 min = .34 \u00b1 .18; control: baseline = .48 \u00b1 .32, 5 min = .37 \u00b1 .27, 15 min = .37 \u00b1 .27, 25 min = .37 \u00b1 .29, 35 min = .35 \u00b1 .28). No significant Group \u00d7 Time interaction or group differences in H<jats:sub>max<\/jats:sub>:M<jats:sub>max<\/jats:sub> were found.<\/jats:p><\/jats:sec><jats:sec sec-type=\"conclusions\"><jats:title>Conclusions:<\/jats:title><jats:p>Menthol did not affect quadriceps MNPE in healthy subjects.<\/jats:p><\/jats:sec>","DOI":"10.1123\/jsr.19.1.30","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T12:27:12Z","timestamp":1470832032000},"page":"30-40","source":"Crossref","is-referenced-by-count":9,"title":["Effects of Menthol-Based Counterirritant on Quadriceps Motoneuron-Pool Excitability"],"prefix":"10.1123","volume":"19","author":[{"given":"Daniel H.","family":"Huffman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian G.","family":"Pietrosimone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry L.","family":"Grindstaff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Hart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan A.","family":"Saliba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher D.","family":"Ingersoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"100","container-title":["Journal of Sport Rehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/jsr\/19\/1\/article-p30.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/jsr\/19\/1\/article-p30.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T23:10:54Z","timestamp":1653001854000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/jsr\/19\/1\/article-p30.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1123\/jsr.19.1.30","relation":{},"ISSN":["1056-6716","1543-3072"],"issn-type":[{"value":"1056-6716","type":"print"},{"value":"1543-3072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2]]}}}