{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T06:35:24Z","timestamp":1772692524004,"version":"3.50.1"},"reference-count":0,"publisher":"Human Kinetics","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:sec sec-type=\"context\"><jats:title>Context:<\/jats:title><jats:p>High-voltage pulsed current (HVPC), a form of electrical stimulation, is known to curb edema formation in laboratory animals and is commonly applied for ankle sprains, but the clinical effects remain undocumented.<\/jats:p><\/jats:sec><jats:sec sec-type=\"objective\"><jats:title>Objective:<\/jats:title><jats:p>To determine whether, as an adjunct to routine acute and subacute care, subsensory HVPC applied nearly continuously for the first 72 h after lateral ankle sprains affected time lost to injury.<\/jats:p><\/jats:sec><jats:sec sec-type=\"design\"><jats:title>Design:<\/jats:title><jats:p>Multicenter, randomized, double-blind, placebo-controlled trial.<\/jats:p><\/jats:sec><jats:sec sec-type=\"setting\"><jats:title>Setting:<\/jats:title><jats:p>Data were collected at 9 colleges and universities and 1 professional training site.<\/jats:p><\/jats:sec><jats:sec sec-type=\"participants\"><jats:title>Participants:<\/jats:title><jats:p>50 intercollegiate and professional athletes.<\/jats:p><\/jats:sec><jats:sec sec-type=\"interventions\"><jats:title>Interventions:<\/jats:title><jats:p>Near-continuous live or placebo HVPC for 72 h postinjury in addition to routine acute and subacute care.<\/jats:p><\/jats:sec><jats:sec sec-type=\"main outcome measure\"><jats:title>Main Outcome Measure:<\/jats:title><jats:p>Time lost to injury measured from time of injury until declared fit to play.<\/jats:p><\/jats:sec><jats:sec sec-type=\"results\"><jats:title>Results:<\/jats:title><jats:p>Overall, time lost to injury was not different between treated and control groups (<jats:italic>P<\/jats:italic> = .55). However, grade of injury was a significant factor. Time lost to injury after grade I lateral ankle sprains was greater for athletes receiving live HVPC than for those receiving placebo HVPC (<jats:italic>P<\/jats:italic> = .049), but no differences were found between groups for grade II sprains (<jats:italic>P<\/jats:italic> = .079).<\/jats:p><\/jats:sec><jats:sec sec-type=\"conclusions\"><jats:title>Conclusions:<\/jats:title><jats:p>Application of subsensory HVPC had no clinically meaningful effect on return to play after lateral ankle sprain.<\/jats:p><\/jats:sec>","DOI":"10.1123\/jsr.19.4.399","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T12:27:05Z","timestamp":1470832025000},"page":"399-410","source":"Crossref","is-referenced-by-count":16,"title":["Effect of High-Voltage Pulsed Current on Recovery After Grades I and II Lateral Ankle Sprains"],"prefix":"10.1123","volume":"19","author":[{"given":"Frank C.","family":"Mendel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Dolan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale R.","family":"Fish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Marzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory E.","family":"Wilding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"100","container-title":["Journal of Sport Rehabilitation"],"original-title":[],"link":[{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/jsr\/19\/4\/article-p399.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/jsr\/19\/4\/article-p399.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T23:10:35Z","timestamp":1653001835000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/jsr\/19\/4\/article-p399.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":0,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1123\/jsr.19.4.399","relation":{},"ISSN":["1056-6716","1543-3072"],"issn-type":[{"value":"1056-6716","type":"print"},{"value":"1543-3072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}