{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T09:47:23Z","timestamp":1778665643743,"version":"3.51.4"},"reference-count":42,"publisher":"Human Kinetics","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,9,1]]},"abstract":"<jats:p><jats:italic><jats:bold>Clinical Scenario<\/jats:bold>:<\/jats:italic> Hamstring strains are common athletic injuries, with a high-recurrence rate (34%). Recently, platelet-rich plasma (PRP) injections have gained popularity as a potential treatment option to accelerate healing of hamstring injury. <jats:italic><jats:bold>Focused Clinical Question<\/jats:bold>:<\/jats:italic> Does the combination of PRP injection and rehabilitation decrease recovery time of acute hamstring injury as compared to rehabilitation alone in college athletes? <jats:italic><jats:bold>Summary of Key Findings<\/jats:bold>:<\/jats:italic> A literature search resulted in 3 randomized controlled trials. One study showed benefits in various outcome measures with PRP, compared to rehabilitation alone, while 2 showed no benefits. One study reported improved pain, ultrasonography regenerative indications, and recovery time with PRP injection following acute hamstring injury; however, larger studies have shown no benefits. The literature demonstrates conflicting evidence regarding benefits of PRP injections in hamstring injuries. <jats:italic><jats:bold>Clinical Bottom Line<\/jats:bold>:<\/jats:italic> At this time, PRP injections cannot be recommended as having value for hamstring injuries, compared to rehabilitation alone. <jats:italic><jats:bold>Strength of Recommendation<\/jats:bold>:<\/jats:italic> Due to inconsistent or limited quality patient-oriented evidence in existing literature, the strength of this recommendation is grade B, based on the strength of recommendation taxonomy.<\/jats:p>","DOI":"10.1123\/jsr.2016-0066","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T14:36:41Z","timestamp":1500302201000},"page":"480-484","source":"Crossref","is-referenced-by-count":13,"title":["Effectiveness of PRP Injection in Reducing Recovery Time of Acute Hamstring Injury: A Critically Appraised Topic"],"prefix":"10.1123","volume":"27","author":[{"given":"Mary 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