{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:11:13Z","timestamp":1780049473779,"version":"3.53.1"},"reference-count":45,"publisher":"Human Kinetics","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:p><jats:italic><jats:bold>Context<\/jats:bold>:<\/jats:italic> A variety of approaches have been proposed to prevent lower limb injuries in runners. However, the evidence for the effectiveness of interventions to reduce lower limb pain and injury after intensive running is very weak. <jats:italic><jats:bold>Objective<\/jats:bold>:<\/jats:italic> The authors performed a systematic review to investigate the effects of foot orthoses on pain and the prevention of lower limb injuries in runners. <jats:italic><jats:bold>Evidence Acquisition<\/jats:bold>:<\/jats:italic> The authors searched the MEDLINE\/PubMed, Physiotherapy Evidence Database, Scielo, and Cochrane Central (from inception to February 2022) databases for randomized controlled trials that evaluated the effects of foot orthoses in runners. The authors then calculated mean differences and 95% confidence intervals from these trials. Heterogeneity was assessed using the <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup> test. Furthermore, the authors compared the criteria between runners with foot orthoses and ones with no intervention (control group). <jats:italic><jats:bold>Evidence Synthesis<\/jats:bold>:<\/jats:italic> Twelve studies (5321 runners) met our review criteria. The control and the foot orthoses group sustained 721 (37%) and 238 (24%) injuries, respectively. Compared with the control group, the use of foot orthoses resulted in a significant reduction in lower limb injury risk (risk ratio\u2009=\u20090.6; 95% confidence interval, 0.5\u20130.7; <jats:italic>P<\/jats:italic>\u2009=\u2009.00001, <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u200954%; 7 studies, N\u2009=\u20092983: moderate-quality evidence). Moreover, the foot orthoses group corresponded to a 40% reduction in the risk of developing lower limb injuries. <jats:italic><jats:bold>Conclusions<\/jats:bold>:<\/jats:italic> The use of foot orthoses may help reduce the incidence of lower limb injuries and pain in runners.<\/jats:p>","DOI":"10.1123\/jsr.2021-0302","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T07:35:01Z","timestamp":1657611301000},"page":"1067-1074","source":"Crossref","is-referenced-by-count":3,"title":["Effects of Foot Orthoses on Pain and the Prevention of Lower Limb Injuries in Runners: Systematic Review and Meta-Analysis"],"prefix":"10.1123","volume":"31","author":[{"given":"Murilo","family":"Pires Neves","sequence":"first","affiliation":[{"name":"Post-Graduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physiotherapy Research Group, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physical Therapist Staff, AF FISIOTERAPIA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiano","family":"Sena da Concei\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physiotherapy Research Group, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physical Therapist Staff, AF FISIOTERAPIA, Salvador, BA, Brazil"},{"name":"Physical Therapy Department, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Roberto Garcia","family":"Lucareli","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Sciences, University Nove de Julho, S\u00e3o Paulo, SP, Brazil"},{"name":"Physical Therapist Staff, Einstein Movement Analysis Laboratory, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata Santana da Silva","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physiotherapy Research Group, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Center for Technological Innovation in Rehabilitation\u2014NITRE, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Paulo Bomfim Cruz","family":"Vieira","sequence":"additional","affiliation":[{"name":"Physical Therapist Staff, AF FISIOTERAPIA, Salvador, BA, Brazil"},{"name":"Post-Graduate Program in Medicine and Health, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Al\u00e9cio Jorge Alves de Lima","family":"Brasileiro","sequence":"additional","affiliation":[{"name":"Physical Therapist Staff, AF FISIOTERAPIA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grimaldo Ferreira","family":"da Silva","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physiotherapy Research Group, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansueto","family":"Gomes-Neto","sequence":"additional","affiliation":[{"name":"Post-Graduate Program in Interactive Processes of Organs and Systems, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physiotherapy Research Group, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Physical Therapy Department, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"},{"name":"Post-Graduate Program in Medicine and Health, Federal University of Bahia\u2014UFBA, Salvador, BA, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"100","reference":[{"issue":"14","key":"r1","series-title":"J Am Coll Cardiol","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1016\/j.jacc.2014.04.058","article-title":"Leisure-time running reduces all-cause and cardiovascular mortality risk","volume":"64","author":"Lee DC","year":"2014","unstructured":"Lee DC, Pate RR, Lavie CJ, Sui X, Church TS, Blair SN. 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