{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:23:24Z","timestamp":1756463004898,"version":"3.44.0"},"reference-count":0,"publisher":"Human Kinetics","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec sec-type=\"purpose\"><jats:title>Purpose:<\/jats:title><jats:p>Whole body or leg exercise before a meal can increase insulin sensitivity, but it is unclear whether the same can occur with upper body exercise since a smaller muscle mass is activated. We measured the impact of a single session of handcycle exercise on glucose tolerance and insulin sensitivity.<\/jats:p><\/jats:sec><jats:sec sec-type=\"methods\"><jats:title>Methods:<\/jats:title><jats:p>Nonambulatory (Non-Amb) adolescents with spina bifida or cerebral palsy (4F\/3M), or ambulatory peers (Control, 4F\/7M) completed 2 glucose tolerance tests on separate days, preceded by either rest or a 35-min bout of moderate-to-vigorous intermittent handcycle exercise.<\/jats:p><\/jats:sec><jats:sec sec-type=\"results\"><jats:title>Results:<\/jats:title><jats:p>The Non-Amb group had higher body fat (mean \u00b1 <jats:italic>SD<\/jats:italic>: 38 \u00b1 12%, Control: 24 \u00b1 9, <jats:italic>p<\/jats:italic> = .041) but similar VO<jats:sub>2peak<\/jats:sub> (17.7 \u00b1 6.1 ml\/kg\/min, Control: 21.1 \u00b1 7.9). Fasting glucose and insulin were normal for all participants. Compared with the rest trial, exercise resulted in a reduction in glucose area under the curve (11%, <jats:italic>p<\/jats:italic> = .008) without a significant group x trial interaction and no difference in the magnitude of change between groups. Insulin sensitivity was increased 16% (<jats:italic>p<\/jats:italic> = .028) by exercise in the Control group but was not significantly changed in the Non-Amb group.<\/jats:p><\/jats:sec><jats:sec sec-type=\"conclusion\"><jats:title>Conclusion:<\/jats:title><jats:p>A single bout of handcycle exercise improves glucose tolerance in adolescents with and without mobility limitations and could therefore help maintain or improve metabolic health.<\/jats:p><\/jats:sec>","DOI":"10.1123\/pes.2016-0047","type":"journal-article","created":{"date-parts":[[2016,5,13]],"date-time":"2016-05-13T08:43:02Z","timestamp":1463128982000},"page":"63-72","source":"Crossref","is-referenced-by-count":5,"title":["The Effect of Handcycle Ergometer Exercise on Glucose Tolerance in Ambulatory and Non-Ambulatory Adolescents"],"prefix":"10.1123","volume":"29","author":[{"given":"Kevin R.","family":"Short","sequence":"first","affiliation":[{"name":"University of Oklahoma Health Sciences Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"April M.","family":"Teague","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jake C.","family":"Klein","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Malm-Buatsi","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic","family":"Frimberger","sequence":"additional","affiliation":[{"name":"University of Oklahoma Health Sciences Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"100","container-title":["Pediatric Exercise Science"],"original-title":[],"link":[{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/pes\/29\/1\/article-p63.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/pes\/29\/1\/article-p63.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.humankinetics.com\/downloadpdf\/journals\/pes\/29\/1\/article-p63.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T23:08:29Z","timestamp":1756336109000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.humankinetics.com\/view\/journals\/pes\/29\/1\/article-p63.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1123\/pes.2016-0047","relation":{},"ISSN":["0899-8493","1543-2920"],"issn-type":[{"type":"print","value":"0899-8493"},{"type":"electronic","value":"1543-2920"}],"subject":[],"published":{"date-parts":[[2017,2]]}}}