{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:58Z","timestamp":1756425658348,"version":"3.44.0"},"reference-count":43,"publisher":"Human Kinetics","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,8,1]]},"abstract":"<jats:p><jats:italic><jats:bold>Purpose<\/jats:bold>:<\/jats:italic> The effect of exercise intensity on vasodilator function is poorly understood in children. The authors compared the acute effect of high-intensity interval exercise (HIIE) with moderate-intensity steady-state exercise (MISS) on postexercise vasodilation and shear patterns in 7- to 12- year-old children. <jats:italic><jats:bold>Methods<\/jats:bold>:<\/jats:italic> Superficial femoral artery diameter, shear rates, and flow-mediated dilation were measured pre, immediately following (post), and 1 hour after (post60) HIIE (six 1-min sprints at 90% peak power [W<jats:sub>max<\/jats:sub>], with 1-min recovery) and MISS (15\u00a0min at 44% W<jats:sub>max<\/jats:sub>). <jats:italic><jats:bold>Results<\/jats:bold>:<\/jats:italic> Baseline superficial femoral artery diameter increased similarly following both HIIE (pre 4.23 [0.41]\u00a0mm, post 4.73 [0.56]\u00a0mm) and MISS (pre 4.28 [0.56]\u00a0mm, post 4.59 [0.64]\u00a0mm), returning to preexercise values post60. Blood flow and antegrade shear rate were increased post HIIE and MISS, but to a greater extent, post HIIE (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). Retrograde shear rate was attenuated post both exercise conditions and remained post60 (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). There was a decline in flow-mediated dilation postexercise (HIIE \u0394 \u22122.9%; MISS \u0394 \u22122.4%), which was no longer apparent when corrected for baseline diameter. <jats:italic><jats:bold>Conclusion<\/jats:bold>:<\/jats:italic> Acute bouts of external work-matched HIIE or MISS exert a similar impact on shear-mediated conduit artery vasodilation and flow-mediated dilation in children, and this is reversed 1 hour after exercise.<\/jats:p>","DOI":"10.1123\/pes.2019-0003","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:21:10Z","timestamp":1560126070000},"page":"282-289","source":"Crossref","is-referenced-by-count":4,"title":["The Impact of Different Exercise Intensities on Vasodilation and Shear Rate Patterns in Children"],"prefix":"10.1123","volume":"31","author":[{"given":"Ali M.","family":"McManus","sequence":"first","affiliation":[{"name":"University of British Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan R.","family":"Sletten","sequence":"additional","affiliation":[{"name":"University of British Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Green","sequence":"additional","affiliation":[{"name":"The University of Western Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"100","reference":[{"key":"r1","series-title":"Pediatr Res","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1203\/01.PDR.0000170900.35571.CB","article-title":"Noninvasive assessment of arterial stiffness and risk of atherosclerotic events in children","volume":"58","author":"Aggoun Y","year":"2005","unstructured":"Aggoun Y, Szezepanski I, Bonnet D. 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