{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:31:36Z","timestamp":1793637096903,"version":"4.5.1"},"reference-count":57,"publisher":"Human Kinetics","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,1]]},"abstract":"<jats:p>\n                    <jats:italic>\n                      <jats:bold>Purpose<\/jats:bold>\n                      :\n                    <\/jats:italic>\n                    To investigate associations of physical activity (PA) and sedentary time accumulated from childhood to adolescence with arterial stiffness and structure in adolescence.\n                    <jats:italic>\n                      <jats:bold>Method<\/jats:bold>\n                      :\n                    <\/jats:italic>\n                    Altogether 175 (83 girls) children participated in the study (average baseline age 7.6 [0.4]\u00a0y). Physical activity energy expenditure, PA, and sedentary time were estimated using a combined accelerometer and heart rate monitor at baseline and 2- and 8-year follow-ups. Cumulative exposures were computed using area under the curves. Carotid-femoral pulse wave velocity and cardio-ankle vascular index were assessed using impedance cardiography, and carotid artery distensibility and carotid intima-media thickness was assessed using ultrasonography. Data were analyzed using linear regression models adjusted for age and sex and separately for systolic blood pressure, body fat percentage, and pubertal stage.\n                    <jats:italic>\n                      <jats:bold>Results<\/jats:bold>\n                      :\n                    <\/jats:italic>\n                    No statistically significant associations were found in the complete sample or in boys (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&gt;\u2009.05). Higher cumulative PA energy expenditure (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2009=\u2009\u22120.260; 95% CI, \u22120.495 to \u22120.025) and moderate to vigorous PA (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2009=\u2009\u22120.341; 95% CI, \u22120.570 to \u22120.112) were associated with lower carotid-femoral pulse wave velocity, and higher cumulative moderate to vigorous PA (\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2009=\u2009\u22120.346; 95% CI, \u22120.573 to \u22120.118) was associated with lower cardio-ankle vascular index at 8\u00a0years in girls.\n                    <jats:italic>\n                      <jats:bold>Conclusion<\/jats:bold>\n                      :\n                    <\/jats:italic>\n                    In girls, higher PA, especially moderate to vigorous PA, may slow arterial stiffening, whereas boys may already be physically active beyond levels that yield further benefits.\n                  <\/jats:p>","DOI":"10.1123\/pes.2025-0177","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:36:38Z","timestamp":1792604198000},"page":"412-420","source":"Crossref","is-referenced-by-count":0,"title":["Associations of Accumulating Physical Activity and Sedentary Time From Childhood to Adolescence With Arterial Stiffness and Structure in Adolescence\u2014An 8-Year Follow-Up Study"],"prefix":"10.1123","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1132-9730","authenticated-orcid":true,"given":"Emilia","family":"Laitinen","sequence":"first","affiliation":[{"name":"Faculty of Sport and Health Sciences, University of Jyv\u00e4skyl\u00e4, Jyv\u00e4skyl\u00e4, 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