{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T03:22:58Z","timestamp":1768274578894,"version":"3.49.0"},"reference-count":51,"publisher":"Human Kinetics","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,1]]},"abstract":"<jats:p><jats:italic><jats:bold>Background<\/jats:bold>:<\/jats:italic> We investigated the associations of replacing sedentary behavior (SB) with physical activity of different intensities on the physical function of octogenarians living in long-term care facilities. <jats:italic><jats:bold>Methods<\/jats:bold>:<\/jats:italic> This pooled study recruited 427 older adults aged 80 years and older (69.1% female; body mass index: 27.53). For 345 participants who provided valid data, we assessed device-measured time spent in SB, light-intensity physical activity (LIPA), and moderate to vigorous physical activity (MVPA). We assessed lower limb physical function, strength, mobility, and disability. We used compositional data analysis to investigate the associations of replacing SB with physical activity on the outcomes. <jats:italic><jats:bold>Results<\/jats:bold>:<\/jats:italic> Reallocation of SB to LIPA and MVPA was associated with a higher number of 30-second Chair Stand cycles (LIPA: +0.21, MVPA: +1.81; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), greater peak force (LIPA: +11.96\u00a0N, MVPA: +27.68\u00a0N; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), peak power (LIPA: +35.82\u00a0W, MVPA: +92.73\u00a0W; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), peak velocity (LIPA: +0.03\u00a0m\/s, MVPA: +0.12\u00a0m\/s; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), higher levels of grip strength (LIPA: +0.68\u00a0kg, MVPA: +2.49\u00a0kg; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and less time in the Time Up and Go (LIPA: \u22127.63\u00a0s, MVPA: \u221212.43\u00a0s; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). <jats:italic><jats:bold>Conclusions<\/jats:bold>:<\/jats:italic> Replacing SB with LIPA or MVPA is associated with physical function and disability of older adults living in long-term care facilities.<\/jats:p>","DOI":"10.1123\/jpah.2021-0186","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T07:36:50Z","timestamp":1648539410000},"page":"329-338","source":"Crossref","is-referenced-by-count":10,"title":["Replacing Sedentary Behavior With Physical Activity of Different Intensities: Implications for Physical Function, Muscle Function, and Disability in Octogenarians Living in Long-Term Care Facilities"],"prefix":"10.1123","volume":"19","author":[{"given":"Jesus","family":"del Pozo-Cruz","sequence":"first","affiliation":[{"name":"Departamento de Educaci\u00f3n F\u00edsica y Deporte, Epidemiology of Physical Activity and Fitness Across Lifespan Research Group (EPAFit), Universidad de Sevilla, Sevilla, Spain"}]},{"given":"Jon","family":"Irazusta","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV\/EHU), Bizkaia, Spain"}]},{"given":"Ana","family":"Rodriguez-Larrad","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV\/EHU), Bizkaia, Spain"}]},{"given":"Rosa M.","family":"Alfonso-Rosa","sequence":"additional","affiliation":[{"name":"Departamento de Motricidad Humana y Rendimiento Deportivo, Epidemiology of Physical Activity and Fitness Across Lifespan Research Group (EPAFit), Universidad de Sevilla, Sevilla, Spain"}]},{"given":"Francisco","family":"\u00c1lvarez-Barbosa","sequence":"additional","affiliation":[{"name":"Departamento de Actividad F\u00edsica y Deporte, CEU Cardenal Esp\u00ednola, Sevilla, Epidemiology of Physical Activity and Fitness Across Lifespan Research Group (EPAFit), Universidad de Sevilla, Sevilla, Spain"}]},{"given":"Armando","family":"Raimundo","sequence":"additional","affiliation":[{"name":"Departamento de Desporto e Sa\u00fade, Escola de Ci\u02c6encias e Tecnologia, Universidade de Evora, Evora, Portugal"}]},{"given":"Soraia","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Departamento de Desporto e Sa\u00fade, Escola de Ci\u02c6encias e Tecnologia, Universidade de Evora, Evora, Portugal"}]},{"given":"Chloe","family":"Rezola-Pardo","sequence":"additional","affiliation":[{"name":"Center for Active and Healthy Ageing, Department of Sports Science and Clinical Biomechanics, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark"}]},{"given":"Borja","family":"del Pozo Cruz","sequence":"additional","affiliation":[{"name":"Center for Active and Healthy Ageing, Department of Sports Science and Clinical Biomechanics, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark"}]}],"member":"100","reference":[{"key":"r1","series-title":"Ageing Res Rev","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.arr.2014.02.008","article-title":"Effects of combined cognitive and exercise interventions on cognition in older adults with and without cognitive impairment: a systematic review","volume":"15","author":"Law LLF","year":"2014","unstructured":"Law LLF, Barnett F, Yau MK, Gray MA. 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