{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T05:09:01Z","timestamp":1740028141300,"version":"3.37.3"},"reference-count":61,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["dmd.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Drug Metabolism and Disposition"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1124\/dmd.124.001720","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T13:00:51Z","timestamp":1715173251000},"page":"681-689","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tissue-, Region-, and Gene-Specific Induction of Microsomal Epoxide Hydrolase Expression and Activity in the Mouse Intestine by Arsenic in Drinking Water"],"prefix":"10.1016","volume":"52","author":[{"given":"Hui","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-Yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1124\/dmd.124.001720_bib1","doi-asserted-by":"crossref","first-page":"9018","DOI":"10.1073\/pnas.0703229104","article-title":"Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo","volume":"104","author":"Ai","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/dmd.124.001720_bib2","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3109\/00498254.2012.754113","article-title":"Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl\/6 mice","volume":"43","author":"Anwar-Mohamed","year":"2013","journal-title":"Xenobiotica"},{"key":"10.1124\/dmd.124.001720_bib3","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3109\/00498254.2012.693971","article-title":"Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl\/6 mouse heart","volume":"42","author":"Anwar-Mohamed","year":"2012","journal-title":"Xenobiotica"},{"key":"10.1124\/dmd.124.001720_bib4","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0006-291X(03)00728-9","article-title":"Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts","volume":"305","author":"Aono","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/dmd.124.001720_bib5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0014-5793(94)80278-5","article-title":"Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins. Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis","volume":"338","author":"Arand","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1124\/dmd.124.001720_bib6","doi-asserted-by":"crossref","first-page":"64312","DOI":"10.1007\/s11356-022-21988-z","article-title":"Arsenic in drinking water: overview of removal strategies and role of chitosan biosorbent for its remediation","volume":"29","author":"Ayub","year":"2022","journal-title":"Environ Sci Pollut Res Int"},{"key":"10.1124\/dmd.124.001720_bib7","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.3390\/antiox11051034","article-title":"Mitochondrial ROS, ER Stress, and Nrf2 Crosstalk in the Regulation of Mitochondrial Apoptosis Induced by Arsenite","volume":"11","author":"Cantoni","year":"2022","journal-title":"Antioxidants"},{"key":"10.1124\/dmd.124.001720_bib8","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.envres.2008.04.001","article-title":"Arsenic in drinking water and lung cancer: a systematic review","volume":"108","author":"Celik","year":"2008","journal-title":"Environ Res"},{"key":"10.1124\/dmd.124.001720_bib9","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.taap.2004.10.023","article-title":"Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan","volume":"206","author":"Chen","year":"2005","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/dmd.124.001720_bib10","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0003-9861(02)00226-6","article-title":"Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individuals","volume":"403","author":"Coles","year":"2002","journal-title":"Arch Biochem Biophys"},{"key":"10.1124\/dmd.124.001720_bib11","doi-asserted-by":"crossref","first-page":"5488","DOI":"10.3390\/molecules25235488","article-title":"Small Molecule Soluble Epoxide Hydrolase Inhibitors in Multitarget and Combination Therapies for Inflammation and Cancer","volume":"25","author":"Das Mahapatra","year":"2020","journal-title":"Molecules"},{"key":"10.1124\/dmd.124.001720_bib12","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1194\/jlr.M024448","article-title":"EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides","volume":"53","author":"Decker","year":"2012","journal-title":"J Lipid Res"},{"key":"10.1124\/dmd.124.001720_bib13","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1289\/ehp.11464","article-title":"Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response","volume":"116","author":"Du","year":"2008","journal-title":"Environ Health Perspect"},{"key":"10.1124\/dmd.124.001720_bib14","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S0026-895X(25)13603-1","article-title":"Rat small intestinal cytochromes P450 probed by warfarin metabolism","volume":"43","author":"Fasco","year":"1993","journal-title":"Mol Pharmacol"},{"key":"10.1124\/dmd.124.001720_bib15","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0009-2797(00)00197-6","article-title":"Epoxide hydrolases: biochemistry and molecular biology","volume":"129","author":"Fretland","year":"2000","journal-title":"Chem Biol Interact"},{"key":"10.1124\/dmd.124.001720_bib16","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.68445","article-title":"EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence","volume":"10","author":"Gautheron","year":"2021","journal-title":"eLife"},{"key":"10.1124\/dmd.124.001720_bib17","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/892579","article-title":"Association of Environmental Arsenic Exposure, Genetic Polymorphisms of Susceptible Genes, and Skin Cancers in Taiwan","volume":"2015","author":"Hsu","year":"2015","journal-title":"BioMed Res Int"},{"key":"10.1124\/dmd.124.001720_bib18","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1128\/MCB.26.3.940-954.2006","article-title":"Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice","volume":"26","author":"Hu","year":"2006","journal-title":"Mol Cell Biol"},{"key":"10.1124\/dmd.124.001720_bib19","first-page":"11","article-title":"Arsenic, metals, fibres, and dusts","volume":"100","year":"2012","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"10.1124\/dmd.124.001720_bib20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1152\/physrev.00021.2011","article-title":"Epoxides and soluble epoxide hydrolase in cardiovascular physiology","volume":"92","author":"Imig","year":"2012","journal-title":"Physiol Rev"},{"key":"10.1124\/dmd.124.001720_bib21","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1080\/13543776.2022.2054329","article-title":"Soluble epoxide hydrolase inhibitors: an overview and patent review from the last decade","volume":"32","author":"Iyer","year":"2022","journal-title":"Expert Opin Ther Pat"},{"key":"10.1124\/dmd.124.001720_bib22","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.tox.2004.08.003","article-title":"An integrated pharmacokinetic and pharmacodynamic study of arsenite action 2. Heme oxygenase induction in mice","volume":"206","author":"Kenyon","year":"2005","journal-title":"Toxicology"},{"key":"10.1124\/dmd.124.001720_bib23","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.3390\/ijms21062056","article-title":"Soluble Epoxide Hydrolase 2 Expression Is Elevated in Obese Humans and Decreased by Physical Activity","volume":"21","author":"Khadir","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1124\/dmd.124.001720_bib24","doi-asserted-by":"crossref","DOI":"10.1289\/EHP6943","article-title":"Arsenic Metabolism in Mice Carrying a BORCS7\/AS3MT Locus Humanized by Syntenic Replacement","volume":"128","author":"Koller","year":"2020","journal-title":"Environ Health Perspect"},{"key":"10.1124\/dmd.124.001720_bib25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/BF03401947","article-title":"Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione","volume":"7","author":"Kwak","year":"2001","journal-title":"Mol Med"},{"key":"10.1124\/dmd.124.001720_bib26","doi-asserted-by":"crossref","first-page":"9177","DOI":"10.1021\/acs.jmedchem.8b00819","article-title":"Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors","volume":"61","author":"Li","year":"2018","journal-title":"J Med Chem"},{"key":"10.1124\/dmd.124.001720_bib27","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.3390\/antiox11091835","article-title":"Differential Effects of Arsenic in Drinking Water on Mouse Hepatic and Intestinal Heme Oxygenase-1 Expression","volume":"11","author":"Li","year":"2022","journal-title":"Antioxidants"},{"key":"10.1124\/dmd.124.001720_bib28","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.taap.2017.10.016","article-title":"Tetramethylpyrazine suppresses angiotensin II-induced soluble epoxide hydrolase expression in coronary endothelium via anti-ER stress mechanism","volume":"336","author":"Mak","year":"2017","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/dmd.124.001720_bib29","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0039-9140(02)00268-0","article-title":"Arsenic round the world: a review","volume":"58","author":"Mandal","year":"2002","journal-title":"Talanta"},{"key":"10.1124\/dmd.124.001720_bib30","doi-asserted-by":"crossref","first-page":"3571","DOI":"10.1007\/s00204-017-2060-4","article-title":"Beyond detoxification: a role for mouse mEH in the hepatic metabolism of endogenous lipids","volume":"91","author":"Marowsky","year":"2017","journal-title":"Arch Toxicol"},{"key":"10.1124\/dmd.124.001720_bib31","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.taap.2004.08.025","article-title":"Effect of chronic intake of arsenic-contaminated water on liver","volume":"206","author":"Mazumder","year":"2005","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/dmd.124.001720_bib32","doi-asserted-by":"crossref","first-page":"4993","DOI":"10.3390\/ijms22094993","article-title":"Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues","volume":"22","author":"Morisseau","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1124\/dmd.124.001720_bib33","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0022-3565(24)39291-2","article-title":"Expression and localization of multidrug resistant protein mrp2 in rat small intestine","volume":"293","author":"Mottino","year":"2000","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/dmd.124.001720_bib34","series-title":"Maine, 2005-09","article-title":"Assessment of Arsenic Concentrations in Domestic Well Water, by Town","author":"Nielsen","year":"2010"},{"key":"10.1124\/dmd.124.001720_bib35","doi-asserted-by":"crossref","first-page":"703","DOI":"10.3390\/biom10050703","article-title":"Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson\u2019s Disease: A New Therapeutic Strategy","volume":"10","author":"Pall\u00e0s","year":"2020","journal-title":"Biomolecules"},{"key":"10.1124\/dmd.124.001720_bib36","first-page":"1","article-title":"Environmental arsenic as a disruptor of insulin signaling","volume":"10","author":"Paul","year":"2008","journal-title":"Met Ions Biol Med"},{"key":"10.1124\/dmd.124.001720_bib37","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.freeradbiomed.2008.05.020","article-title":"Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2","volume":"45","author":"Pi","year":"2008","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/dmd.124.001720_bib38","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0014-4827(03)00341-0","article-title":"Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide","volume":"290","author":"Pi","year":"2003","journal-title":"Exp Cell Res"},{"key":"10.1124\/dmd.124.001720_bib39","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/toxsci\/kfn267","article-title":"Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species","volume":"108","author":"Reisman","year":"2009","journal-title":"Toxicol Sci"},{"key":"10.1124\/dmd.124.001720_bib40","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.leukres.2017.03.002","article-title":"Anti-angiogenic and anti-multiple myeloma effects of oprozomib (OPZ) alone and in combination with pomalidomide (Pom) and\/or dexamethasone (Dex)","volume":"57","author":"Sanchez","year":"2017","journal-title":"Leuk Res"},{"key":"10.1124\/dmd.124.001720_bib41","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative C(T) method","volume":"3","author":"Schmittgen","year":"2008","journal-title":"Nat Protoc"},{"key":"10.1124\/dmd.124.001720_bib42","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.3390\/w15091751","article-title":"Arsenic in Drinking Water and Diabetes","volume":"15","author":"Shakya","year":"2023","journal-title":"Water"},{"key":"10.1124\/dmd.124.001720_bib43","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0883-2927(02)00018-5","article-title":"A review of the source, behaviour and distribution of arsenic in natural waters","volume":"17","author":"Smedley","year":"2002","journal-title":"Appl Geochem"},{"key":"10.1124\/dmd.124.001720_bib44","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0883-2927(01)00082-8","article-title":"Hydrogeochemistry of arsenic and other inorganic constituents in groundwaters from La Pampa, Argentina","volume":"17","author":"Smedley","year":"2002","journal-title":"Appl Geochem"},{"issue":"Suppl","key":"10.1124\/dmd.124.001720_bib45","article-title":"Arachidonic acid cytochrome P450 epoxygenase pathway","volume":"50","author":"Spector","year":"2009","journal-title":"J Lipid Res"},{"key":"10.1124\/dmd.124.001720_bib46","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.eplepsyres.2015.03.003","article-title":"Brivaracetam and carbamazepine interaction in healthy subjects and in vitro","volume":"113","author":"Stockis","year":"2015","journal-title":"Epilepsy Res"},{"key":"10.1124\/dmd.124.001720_bib47","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.eplepsyres.2016.11.001","article-title":"Pharmacokinetic interaction of brivaracetam on carbamazepine in adult patients with epilepsy, with and without valproate co-administration","volume":"128","author":"Stockis","year":"2016","journal-title":"Epilepsy Res"},{"key":"10.1124\/dmd.124.001720_bib48","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.bbagrm.2014.03.014","article-title":"Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter","volume":"1839","author":"Su","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/dmd.124.001720_bib49","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.mrrev.2006.02.001","article-title":"Arsenic in the aetiology of cancer","volume":"612","author":"Tapio","year":"2006","journal-title":"Mutat Res"},{"issue":"2, Suppl 1","key":"10.1124\/dmd.124.001720_bib50","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2005.11.051","article-title":"Mechanisms of enteral nutrient-enhanced intestinal adaptation","volume":"130","author":"Tappenden","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1124\/dmd.124.001720_bib51","first-page":"6975","article-title":"National primary drinking water regulations; arsenic and clarifications to compliance and new source contaminants monitoring","volume":"66","year":"2001","journal-title":"Fed Regist"},{"key":"10.1124\/dmd.124.001720_bib52","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/0013-9351(80)90049-3","article-title":"Metabolism of 74As-labeled trivalent and pentavalent inorganic arsenic in mice","volume":"21","author":"Vahter","year":"1980","journal-title":"Environ Res"},{"key":"10.1124\/dmd.124.001720_bib53","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.intimp.2018.04.038","article-title":"Copper and arsenic-induced oxidative stress and immune imbalance are associated with activation of heat shock proteins in chicken intestines","volume":"60","author":"Wang","year":"2018","journal-title":"Int Immunopharmacol"},{"key":"10.1124\/dmd.124.001720_bib54","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1124\/dmd.117.075226","article-title":"In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s","volume":"45","author":"Wang","year":"2017","journal-title":"Drug Metab Dispos"},{"year":"2003","series-title":"Arsenic in drinking-water: background document for development of WHO guidelines for drinking-water quality","key":"10.1124\/dmd.124.001720_bib55"},{"key":"10.1124\/dmd.124.001720_bib56","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1124\/dmd.116.069914","article-title":"Cardiotonic Pill Reduces Myocardial Ischemia-Reperfusion Injury via Increasing EET Concentrations in Rats","volume":"44","author":"Xu","year":"2016","journal-title":"Drug Metab Dispos"},{"key":"10.1124\/dmd.124.001720_bib57","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.7150\/ijms.74533","article-title":"Targeting IRE1\u03b1-JNK-c-Jun\/AP-1-sEH Signaling Pathway Improves Myocardial and Coronary Endothelial Function Following Global Myocardial Ischemia\/Reperfusion","volume":"19","author":"Xue","year":"2022","journal-title":"Int J Med Sci"},{"key":"10.1124\/dmd.124.001720_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2023.102955","article-title":"Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR","volume":"299","author":"Yang","year":"2023","journal-title":"J Biol Chem"},{"key":"10.1124\/dmd.124.001720_bib59","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.taap.2003.10.022","article-title":"Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review","volume":"198","author":"Yoshida","year":"2004","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/dmd.124.001720_bib60","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1161\/01.RES.87.11.992","article-title":"Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids","volume":"87","author":"Yu","year":"2000","journal-title":"Circ Res"},{"key":"10.1124\/dmd.124.001720_bib61","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1124\/dmd.31.11.1346","article-title":"Characterization of mouse small intestinal cytochrome P450 expression","volume":"31","author":"Zhang","year":"2003","journal-title":"Drug Metab Dispos"}],"container-title":["Drug Metabolism and Disposition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009095562400713X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009095562400713X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/dmd.124.001720","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T08:51:16Z","timestamp":1739955076000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009095562400713X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":61,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S009095562400713X"],"URL":"https:\/\/doi.org\/10.1124\/dmd.124.001720","relation":{},"ISSN":["0090-9556"],"issn-type":[{"type":"print","value":"0090-9556"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tissue-, Region-, and Gene-Specific Induction of Microsomal Epoxide Hydrolase Expression and Activity in the Mouse Intestine by Arsenic in Drinking Water","name":"articletitle","label":"Article Title"},{"value":"Drug Metabolism and Disposition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/dmd.124.001720","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by The American Society for Pharmacology and Experimental Therapeutics","name":"copyright","label":"Copyright"}]}}