{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:34:57Z","timestamp":1788996897730,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1124\/jpet.105.091488","type":"journal-article","created":{"date-parts":[[2005,11,16]],"date-time":"2005-11-16T19:49:17Z","timestamp":1132170557000},"page":"1119-1124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Glucocorticoid Hormone Regulates the Circadian Coordination of \u03bc-Opioid Receptor Expression in Mouse Brainstem"],"prefix":"10.1016","volume":"315","author":[{"given":"Miyako","family":"Yoshida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Koyanagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayaka","family":"Matsuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiro","family":"Fujioka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideto","family":"To","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigehiro","family":"Ohdo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1124\/jpet.105.091488_bib1","doi-asserted-by":"crossref","unstructured":"Antoch MP, Song EJ, Chang AM, Vitaterna MH, Zhao Y, Wilsbacher LD, Sangoram AM, King DP, Pinto LH, and Takahashi JS (1997) Functional identification of the mouse circadian clock gene by transgenic BAC rescue. Cell 89: 655\u2013667.","DOI":"10.1016\/S0092-8674(00)80246-9"},{"key":"10.1124\/jpet.105.091488_bib2","doi-asserted-by":"crossref","unstructured":"Bansinath M, Ranabadran K, Tirndorf H, and Erny P (1990) Effects of the benzomorphan \u03ba-opiate, MR2266 and its (+) enantiomer MR2267, on thermonociceptive reactions in different strains of mice. Neurosci Lett 117: 212\u2013217.","DOI":"10.1016\/0304-3940(90)90146-Z"},{"key":"10.1124\/jpet.105.091488_bib3","doi-asserted-by":"crossref","unstructured":"Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, Reichardt HM, Schutz G, and Schibler U (2000) Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science (Wash DC) 289: 2344\u20132347.","DOI":"10.1126\/science.289.5488.2344"},{"key":"10.1124\/jpet.105.091488_bib4","doi-asserted-by":"crossref","unstructured":"Balsalobre A, Damiola F, and Schibler U (1998) A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93: 929\u2013937.","DOI":"10.1016\/S0092-8674(00)81199-X"},{"key":"10.1124\/jpet.105.091488_bib5","unstructured":"Franklin K and Paxinos G (1997) The Mouse Brain in Stereotaxic Coordinates, Academic Press, San Diego."},{"key":"10.1124\/jpet.105.091488_bib6","doi-asserted-by":"crossref","unstructured":"Frederickson RC, Burgis V, and Edwards JD (1977) Hyperalgesia induced by naloxone follows diurnal rhythm in responsivity to painful stimuli. Science (Wash DC) 198: 756\u2013758.","DOI":"10.1126\/science.561998"},{"key":"10.1124\/jpet.105.091488_bib7","doi-asserted-by":"crossref","unstructured":"Gekakis N, Staknis D, Nguyen HB, Davis FC, Wilsbacher LD, King DP, Takahashi JS, and Weitz CJ (1998) Role of the CLOCK protein in the mammalian circadian mechanism. Science (Wash DC) 280: 1564\u20131569.","DOI":"10.1126\/science.280.5369.1564"},{"key":"10.1124\/jpet.105.091488_bib8","doi-asserted-by":"crossref","unstructured":"Jin X, Shearman LP, Weaver DR, Zylka MJ, Vries GJD, and Reppert SM (1999) A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell 96: 57\u201368.","DOI":"10.1016\/S0092-8674(00)80959-9"},{"key":"10.1124\/jpet.105.091488_bib9","doi-asserted-by":"crossref","unstructured":"Kalsbeek A, Van Heerikhuize JJ, Wortel J, and Buijs RM (1996) A diurnal rhythm of stimulatory input to the hypothalamo-pituitary-adrenal system as revealed by timed intrahypothalamic administration of the vasopressin V1 antagonist. J Neurosci 16: 5555\u20135565.","DOI":"10.1523\/JNEUROSCI.16-17-05555.1996"},{"key":"10.1124\/jpet.105.091488_bib10","doi-asserted-by":"crossref","unstructured":"Kavaliers M and Hirst M (1983) Daily rhythms of analgesia in mice: effects of age and photoperiod. Brain Res 279: 387\u2013393.","DOI":"10.1016\/0006-8993(83)90216-0"},{"key":"10.1124\/jpet.105.091488_bib11","unstructured":"Koyanagi S, Kuramoto Y, Nakagawa H, Aramaki H, Ohdo S, Soeda S, and Shimeno H (2003) A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells. Cancer Res 63: 7277\u20137283."},{"key":"10.1124\/jpet.105.091488_bib12","doi-asserted-by":"crossref","unstructured":"Koyanagi S and Ohdo S (2002) Alteration of intrinsic biological rhythms during interferon treatment and its possible mechanism. Mol Pharmacol 62: 1393\u20131399.","DOI":"10.1124\/mol.62.6.1393"},{"key":"10.1124\/jpet.105.091488_bib13","doi-asserted-by":"crossref","unstructured":"Kume K, Zylka MJ, Sriram S, Shearman LP, Weaver DR, Jin X, Maywood ES, Hastings MH, and Reppert SM (1999) mCRY1 and mCRY2 are essential components of the negative limb of the circadian feedback loop. Cell 98: 193\u2013205.","DOI":"10.1016\/S0092-8674(00)81014-4"},{"key":"10.1124\/jpet.105.091488_bib14","doi-asserted-by":"crossref","unstructured":"Min BH, Augustin LB, Felsheim RF, Fuchs JA, and Loh HH (1994) Genomic structure analysis of promoter sequence of a mouse mu opioid receptor gene. Proc Natl Acad Sci USA 91: 9081\u20139085.","DOI":"10.1073\/pnas.91.19.9081"},{"key":"10.1124\/jpet.105.091488_bib15","doi-asserted-by":"crossref","unstructured":"Moore RY and Eichler VB (1972) Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Res 42: 201\u2013206.","DOI":"10.1016\/0006-8993(72)90054-6"},{"key":"10.1124\/jpet.105.091488_bib16","doi-asserted-by":"crossref","unstructured":"Muglia L, Jacobson L, Pieter Dikkes P, and Majzoub JA (1995) Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature (Lond) 373: 427\u2013432.","DOI":"10.1038\/373427a0"},{"key":"10.1124\/jpet.105.091488_bib17","doi-asserted-by":"crossref","unstructured":"Naber D, Wirz-Justice A, and Kafka MS (1981) Circadian rhythm in rat brain opiate receptor. Neurosci Lett 21: 45\u201350.","DOI":"10.1016\/0304-3940(81)90055-0"},{"key":"10.1124\/jpet.105.091488_bib18","doi-asserted-by":"crossref","unstructured":"Ohdo S, Koyanagi S, Suyama H, Higuchi S, and Aramaki H (2001) Changing the dosing schedule minimizes the disruptive effects of interferon on clock function. Nat Med 7: 356\u2013360.","DOI":"10.1038\/85507"},{"key":"10.1124\/jpet.105.091488_bib19","doi-asserted-by":"crossref","unstructured":"Ohdo S, Nakano S, and Ogawa N (1988) Chronopharmacological study of sodium valproate in mice: dose-concentration-response relationship. Jpn J Pharmacol 47: 11\u201319.","DOI":"10.1016\/S0021-5198(19)43245-9"},{"key":"10.1124\/jpet.105.091488_bib20","doi-asserted-by":"crossref","unstructured":"Pieretti S, Di Giannuario A, Domenici MR, Sagratella S, Capasso A, Sorrentino L, and Loizzo A (1994) Dexamethasone-induced selective inhibition of the central \u03bc-opioid receptor: functional in vivo and in vitro evidence in rodents. Br J Pharmacol 113: 1416\u20131422.","DOI":"10.1111\/j.1476-5381.1994.tb17155.x"},{"key":"10.1124\/jpet.105.091488_bib21","doi-asserted-by":"crossref","unstructured":"Ripperger JA, Shearman LP, Reppert SM, and Schibler U (2000) CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. Genes Dev 14: 679\u2013689.","DOI":"10.1101\/gad.14.6.679"},{"key":"10.1124\/jpet.105.091488_bib22","doi-asserted-by":"crossref","unstructured":"Sangoram AM, Saez L, Antoch MP, Gekakis N, Staknis D, Whiteley A, Fruechte EM, Vitaterna MH, Shimomura K, King DP, et al. (1998) Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription. Neuron 21: 1101\u20131113.","DOI":"10.1016\/S0896-6273(00)80627-3"},{"key":"10.1124\/jpet.105.091488_bib23","doi-asserted-by":"crossref","unstructured":"Shearman LP, Sriram S, Weaver DR, Maywood ES, Chaves I, Zheng B, Kume K, Lee CC, Horst GTJ, Hastings MH, et al. (2000) Interacting molecular loops in the mammalian circadian clock. Science (Wash DC) 288: 1013\u20131019.","DOI":"10.1126\/science.288.5468.1013"},{"key":"10.1124\/jpet.105.091488_bib24","doi-asserted-by":"crossref","unstructured":"Terazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M, Udo R, Ohdo S, Okamura H, and Shibata S (2003) Adrenergic regulation of clock gene expression in mouse liver. Proc Natl Acad Sci USA 100: 6795\u20136800.","DOI":"10.1073\/pnas.0936797100"},{"key":"10.1124\/jpet.105.091488_bib25","unstructured":"Walker CA and Owasoyo JO (1974) The influence of serotonin, GABA and DL-dopa on the circadian rhythm in the toxicity of picrotoxin, pentylenetetrazol and phenobarbital in mice. Int J Chronobiol 2: 125\u2013130."},{"key":"10.1124\/jpet.105.091488_bib26","doi-asserted-by":"crossref","unstructured":"Wendel B and Hoehe MR (1998) The human mu opioid receptor gene: 5\u2032 regulatory and intronic sequences. J Mol Med 76: 525\u2013532.","DOI":"10.1007\/s001090050246"},{"key":"10.1124\/jpet.105.091488_bib27","doi-asserted-by":"crossref","unstructured":"Yoshida M, Ohdo S, Takane H, Tomiyoshi Y, Matsuo A, Yukawa E, and Higuchi S (2003) Chronopharmacology of analgesic effect and its tolerance induced by morphine in mice. J Pharmacol Exp Ther 305: 1200\u20131205.","DOI":"10.1124\/jpet.103.049031"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524323547?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524323547?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/jpet.105.091488","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T21:40:11Z","timestamp":1740001211000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356524323547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0022356524323547"],"URL":"https:\/\/doi.org\/10.1124\/jpet.105.091488","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glucocorticoid Hormone Regulates the Circadian Coordination of \u03bc-Opioid Receptor Expression in Mouse Brainstem","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/jpet.105.091488","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2005 The American Society for Pharmacology and Experimental Therapeutics","name":"copyright","label":"Copyright"}]}}