{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:02:54Z","timestamp":1790017374290,"version":"4.0.1"},"reference-count":61,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1124\/jpet.119.256560","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T01:15:23Z","timestamp":1560820523000},"page":"219-230","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Tetrabenazine Facilitates Exocytosis by Enhancing Calcium-Induced Calcium Release through Ryanodine Receptors"],"prefix":"10.1016","volume":"371","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6628-6097","authenticated-orcid":false,"given":"Ricardo","family":"de Pascual","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"\u00c1lvarez-Ortego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6456-7589","authenticated-orcid":false,"given":"Crist\u00f3bal","family":"de los R\u00edos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gema","family":"Jacob-Mazariego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio G.","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1124\/jpet.119.256560_bib1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1083\/jcb.144.2.241","article-title":"Ca2+-induced Ca2+ release in chromaffin cells seen from inside the ER with targeted aequorin","volume":"144","author":"Alonso","year":"1999","journal-title":"J Cell Biol"},{"key":"10.1124\/jpet.119.256560_bib2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s12640-013-9454-8","article-title":"Antidepressant-like effect of tetrahydroisoquinoline amines in the animal model of depressive disorder induced by repeated administration of a low dose of reserpine: behavioral and neurochemical studies in the rat","volume":"26","author":"Antkiewicz-Michaluk","year":"2014","journal-title":"Neurotox Res"},{"key":"10.1124\/jpet.119.256560_bib3","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.bbrc.2007.10.151","article-title":"A two-step model for acetylcholine control of exocytosis via nicotinic receptors","volume":"365","author":"Arn\u00e1iz-Cot","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/jpet.119.256560_bib4","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00374966","article-title":"Small-conductance Ca(2+)-activated K+ channels in bovine chromaffin cells","volume":"423","author":"Artalejo","year":"1993","journal-title":"Pflugers Arch"},{"key":"10.1124\/jpet.119.256560_bib5","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/276620a0","article-title":"Calcium-dependent exocytosis in bovine adrenal medullary cells with leaky plasma membranes","volume":"276","author":"Baker","year":"1978","journal-title":"Nature"},{"key":"10.1124\/jpet.119.256560_bib6","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1212\/WNL.0b013e3182a1ab4a","article-title":"Monoamine transporters: structure, regulation, and clinical implications","volume":"81","author":"Benarroch","year":"2013","journal-title":"Neurology"},{"key":"10.1124\/jpet.119.256560_bib7","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.physbeh.2015.07.033","article-title":"Depressive-like symptoms in a reserpine-induced model of fibromyalgia in rats","volume":"151","author":"Blasco-Serra","year":"2015","journal-title":"Physiol Behav"},{"key":"10.1124\/jpet.119.256560_bib8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0165-0270(86)90054-3","article-title":"Continuous monitoring of catecholamine release from perfused cat adrenals","volume":"16","author":"Borges","year":"1986","journal-title":"J Neurosci Methods"},{"key":"10.1124\/jpet.119.256560_bib9","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/S0006-3495(03)74567-6","article-title":"Distinct potentiation of L-type currents and secretion by cAMP in rat chromaffin cells","volume":"85","author":"Carabelli","year":"2003","journal-title":"Biophys J"},{"key":"10.1124\/jpet.119.256560_bib10","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF01870956","article-title":"Effects of calcium and Bay K-8644 on calcium currents in adrenal medullary chromaffin cells","volume":"112","author":"Ce\u00f1a","year":"1989","journal-title":"J Membr Biol"},{"key":"10.1124\/jpet.119.256560_bib11","doi-asserted-by":"crossref","first-page":"27076","DOI":"10.1016\/S0021-9258(19)74220-3","article-title":"Quantal Ca2+ release from caffeine-sensitive stores in adrenal chromaffin cells","volume":"268","author":"Cheek","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1124\/jpet.119.256560_bib12","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1042\/bj3040469","article-title":"Histamine-induced Ca2+ entry precedes Ca2+ mobilization in bovine adrenal chromaffin cells","volume":"304","author":"Cheek","year":"1994","journal-title":"Biochem J"},{"key":"10.1124\/jpet.119.256560_bib13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0014-5793(90)81514-O","article-title":"The caffeine-sensitive Ca2+ store in bovine adrenal chromaffin cells; an examination of its role in triggering secretion and Ca2+ homeostasis","volume":"266","author":"Cheek","year":"1990","journal-title":"FEBS Lett"},{"key":"10.1124\/jpet.119.256560_bib14","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40734-017-0051-5","article-title":"Indirect tolerability comparison of deutetrabenazine and tetrabenazine for Huntington disease","volume":"4","author":"Claassen","year":"2017","journal-title":"J Clin Mov Disord"},{"key":"10.1124\/jpet.119.256560_bib15","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00424-002-0810-4","article-title":"Acetylcholine and potassium elicit different patterns of exocytosis in chromaffin cells when the intracellular calcium handling is disturbed","volume":"444","author":"Cuchillo-Ib\u00e1\u00f1ez","year":"2002","journal-title":"Pflugers Arch"},{"key":"10.1124\/jpet.119.256560_bib16","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2147\/DDDT.S138828","article-title":"Review of deutetrabenazine: a novel treatment for chorea associated with Huntington\u2019s disease","volume":"12","author":"Dean","year":"2018","journal-title":"Drug Des Devel Ther"},{"key":"10.1124\/jpet.119.256560_bib17","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ejphar.2008.09.003","article-title":"A low nicotine concentration augments vesicle motion and exocytosis triggered by K(+) depolarisation of chromaffin cells","volume":"598","author":"de Diego","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1124\/jpet.119.256560_bib18","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1007\/s00424-016-1866-x","article-title":"Regulation by L channels of Ca(2+)-evoked secretory responses in ouabain-treated chromaffin cells","volume":"468","author":"De Pascual","year":"2016","journal-title":"Pflugers Arch"},{"key":"10.1124\/jpet.119.256560_bib19","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ejphar.2007.04.050","article-title":"Ouabain augments and maintains the catecholamine release responses evoked by repetitive pulses of potassium, caffeine or histamine in perifused bovine chromaffin cells","volume":"568","author":"de Pascual","year":"2007","journal-title":"Eur J Pharmacol"},{"key":"10.1124\/jpet.119.256560_bib20","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1113\/jphysiol.1975.sp010827","article-title":"Release of catecholamines and dopamine beta-hydroxylase from the perfused adrenal gland of the cat","volume":"244","author":"Dixon","year":"1975","journal-title":"J Physiol"},{"key":"10.1124\/jpet.119.256560_bib21","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1113\/jphysiol.1963.sp007150","article-title":"The mechanism of catecholamine release from the adrenal medulla and the role of calcium in stimulus-secretion coupling","volume":"167","author":"Douglas","year":"1963","journal-title":"J Physiol"},{"key":"10.1124\/jpet.119.256560_bib22","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF02736786","article-title":"Reserpine- and tetrabenazine-sensitive transport of (3)H-histamine by the neuronal isoform of the vesicular monoamine transporter","volume":"6","author":"Erickson","year":"1995","journal-title":"J Mol Neurosci"},{"key":"10.1124\/jpet.119.256560_bib23","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1113\/jphysiol.1982.sp014394","article-title":"Sodium and calcium channels in bovine chromaffin cells","volume":"331","author":"Fenwick","year":"1982","journal-title":"J Physiol"},{"key":"10.1124\/jpet.119.256560_bib24","doi-asserted-by":"crossref","first-page":"7256","DOI":"10.1073\/pnas.82.21.7256","article-title":"Localization of Ca2+ release channels with ryanodine in junctional terminal cisternae of sarcoplasmic reticulum of fast skeletal muscle","volume":"82","author":"Fleischer","year":"1985","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/jpet.119.256560_bib25","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1152\/physrev.00039.2005","article-title":"Calcium signaling and exocytosis in adrenal chromaffin cells","volume":"86","author":"Garc\u00eda","year":"2006","journal-title":"Physiol Rev"},{"key":"10.1124\/jpet.119.256560_bib26","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/309069a0","article-title":"Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels","volume":"309","author":"Garc\u00eda","year":"1984","journal-title":"Nature"},{"key":"10.1124\/jpet.119.256560_bib27","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/S0896-6273(00)80147-6","article-title":"Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granules","volume":"16","author":"Gillis","year":"1996","journal-title":"Neuron"},{"key":"10.1124\/jpet.119.256560_bib28","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/0006-2952(88)90195-5","article-title":"Cyclopiazonic acid inhibition of the Ca2+-transport ATPase in rat skeletal muscle sarcoplasmic reticulum vesicles","volume":"37","author":"Goeger","year":"1988","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/jpet.119.256560_bib29","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/0003-2697(81)90191-3","article-title":"On-line measurement of catecholamine secretion","volume":"110","author":"Green","year":"1981","journal-title":"Anal Biochem"},{"key":"10.1124\/jpet.119.256560_bib30","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF00656997","article-title":"Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches","volume":"391","author":"Hamill","year":"1981","journal-title":"Pflugers Arch"},{"key":"10.1124\/jpet.119.256560_bib31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0024-3205(75)90207-6","article-title":"Electroconvulsive shock: sustained decrease in norepinephrine uptake affinity in a reserpine model of depression","volume":"16","author":"Hendley","year":"1975","journal-title":"Life Sci"},{"key":"10.1124\/jpet.119.256560_bib32","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1242\/jeb.196.1.251","article-title":"Biochemistry and molecular biology of the vesicular monoamine transporter from chromaffin granules","volume":"196","author":"Henry","year":"1994","journal-title":"J Exp Biol"},{"key":"10.1124\/jpet.119.256560_bib33","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1523\/JNEUROSCI.21-08-02553.2001","article-title":"Calcium-dependent inhibition of L, N, and P\/Q Ca2+ channels in chromaffin cells: role of mitochondria","volume":"21","author":"Hern\u00e1ndez-Guijo","year":"2001","journal-title":"J Neurosci"},{"key":"10.1124\/jpet.119.256560_bib34","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1212\/01.wnl.0000198586.85250.13","article-title":"Tetrabenazine as antichorea therapy in Huntington disease: a randomized controlled trial","volume":"66","year":"2006","journal-title":"Neurology"},{"key":"10.1124\/jpet.119.256560_bib35","first-page":"897","article-title":"Repeated treatment with reserpine as a progressive animal model of depression","volume":"30","author":"Ikram","year":"2017","journal-title":"Pak J Pharm Sci"},{"key":"10.1124\/jpet.119.256560_bib36","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1080\/14656566.2016.1258063","article-title":"Dopamine depleters in the treatment of hyperkinetic movement disorders","volume":"17","author":"Jankovic","year":"2016","journal-title":"Expert Opin Pharmacother"},{"key":"10.1124\/jpet.119.256560_bib37","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1002\/mds.25996","article-title":"Chorea associated with Huntington\u2019s disease: to treat or not to treat?","volume":"29","author":"Jankovic","year":"2014","journal-title":"Mov Disord"},{"key":"10.1124\/jpet.119.256560_bib38","doi-asserted-by":"crossref","first-page":"C1211","DOI":"10.1152\/ajpcell.1997.272.4.C1211","article-title":"A caffeine-sensitive Ca2+ store modulates K+-evoked secretion in chromaffin cells","volume":"272","author":"Lara","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1124\/jpet.119.256560_bib39","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1016\/S0021-9258(18)61565-0","article-title":"The effects of ryanodine on passive calcium fluxes across sarcoplasmic reticulum membranes","volume":"262","author":"Lattanzio","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1124\/jpet.119.256560_bib40","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.ceca.2012.01.005","article-title":"Calcium channel types contributing to chromaffin cell excitability, exocytosis and endocytosis","volume":"51","author":"Mahapatra","year":"2012","journal-title":"Cell Calcium"},{"key":"10.1124\/jpet.119.256560_bib41","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.neuint.2010.02.011","article-title":"Reserpine-induced reduction in norepinephrine transporter function requires catecholamine storage vesicles","volume":"56","author":"Mandela","year":"2010","journal-title":"Neurochem Int"},{"key":"10.1124\/jpet.119.256560_bib42","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00424-017-2035-6","article-title":"How intravesicular composition affects exocytosis","volume":"470","author":"Mark Wightman","year":"2018","journal-title":"Pflugers Arch"},{"key":"10.1124\/jpet.119.256560_bib43","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1093\/oxfordjournals.jbchem.a021780","article-title":"2APB, 2-aminoethoxydiphenyl borate, a membrane-penetrable modulator of Ins(1,4,5)P3-induced Ca2+ release","volume":"122","author":"Maruyama","year":"1997","journal-title":"J Biochem"},{"key":"10.1124\/jpet.119.256560_bib44","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.ceca.2011.06.002","article-title":"Ouabain enhances exocytosis through the regulation of calcium handling by the endoplasmic reticulum of chromaffin cells","volume":"50","author":"Milla","year":"2011","journal-title":"Cell Calcium"},{"key":"10.1124\/jpet.119.256560_bib45","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0003-2697(90)90287-J","article-title":"Separation and culture of living adrenaline- and noradrenaline-containing cells from bovine adrenal medullae","volume":"185","author":"Moro","year":"1990","journal-title":"Anal Biochem"},{"key":"10.1124\/jpet.119.256560_bib46","doi-asserted-by":"crossref","first-page":"9136","DOI":"10.1074\/jbc.275.13.9136","article-title":"Vesicular Ca(2+) participates in the catalysis of exocytosis","volume":"275","author":"Mundorf","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/jpet.119.256560_bib47","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0896-6273(00)80983-6","article-title":"Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter release","volume":"20","author":"Neher","year":"1998","journal-title":"Neuron"},{"key":"10.1124\/jpet.119.256560_bib48","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1469-7793.1998.131bu.x","article-title":"Changes in [Ca2+]i and membrane currents during impaired mitochondrial metabolism in dissociated rat hippocampal neurons","volume":"507","author":"Nowicky","year":"1998","journal-title":"J Physiol"},{"key":"10.1124\/jpet.119.256560_bib49","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1046\/j.1471-4159.2000.0751132.x","article-title":"Rundown of secretion after depletion of intracellular calcium stores in bovine adrenal chromaffin cells","volume":"75","author":"Pan","year":"2000","journal-title":"J Neurochem"},{"key":"10.1124\/jpet.119.256560_bib50","doi-asserted-by":"crossref","first-page":"8643","DOI":"10.1016\/S0021-9258(19)84428-9","article-title":"Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles","volume":"261","author":"Pessah","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1124\/jpet.119.256560_bib51","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1126\/science.1075375","article-title":"Emerging roles of presynaptic proteins in Ca++-triggered exocytosis","volume":"298","author":"Rettig","year":"2002","journal-title":"Science"},{"key":"10.1124\/jpet.119.256560_bib52","doi-asserted-by":"crossref","first-page":"17816","DOI":"10.1016\/S0021-9258(19)84646-X","article-title":"Cyclopiazonic acid is a specific inhibitor of the Ca2+-ATPase of sarcoplasmic reticulum","volume":"264","author":"Seidler","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1124\/jpet.119.256560_bib53","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1111\/j.1471-4159.1990.tb02342.x","article-title":"Different patterns of agonist-stimulated increases of 3H-inositol phosphate isomers and cytosolic Ca2+ in bovine adrenal chromaffin cells: comparison of the effects of histamine and angiotensin II","volume":"54","author":"Stauderman","year":"1990","journal-title":"J Neurochem"},{"key":"10.1124\/jpet.119.256560_bib54","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1146\/annurev.cb.06.110190.003435","article-title":"Calcium channels, stores, and oscillations","volume":"6","author":"Tsien","year":"1990","journal-title":"Annu Rev Cell Biol"},{"key":"10.1124\/jpet.119.256560_bib55","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1096\/fj.01-0630com","article-title":"Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells","volume":"16","author":"Villalobos","year":"2002","journal-title":"FASEB J"},{"key":"10.1124\/jpet.119.256560_bib56","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/j.1469-7793.1999.0421v.x","article-title":"Voltage inactivation of Ca2+ entry and secretion associated with N- and P\/Q-type but not L-type Ca2+ channels of bovine chromaffin cells","volume":"516","author":"Villarroya","year":"1999","journal-title":"J Physiol"},{"key":"10.1124\/jpet.119.256560_bib57","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1126\/science.8235626","article-title":"A Ca-dependent early step in the release of catecholamines from adrenal chromaffin cells","volume":"262","author":"von R\u00fcden","year":"1993","journal-title":"Science"},{"key":"10.1124\/jpet.119.256560_bib58","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/BF02736730","article-title":"Localization of vesicular monoamine transporter isoforms (VMAT1 and VMAT2) to endocrine cells and neurons in rat","volume":"5","author":"Weihe","year":"1994","journal-title":"J Mol Neurosci"},{"key":"10.1124\/jpet.119.256560_bib59","doi-asserted-by":"crossref","first-page":"17060","DOI":"10.1073\/pnas.242624699","article-title":"A highly Ca2+-sensitive pool of vesicles is regulated by protein kinase C in adrenal chromaffin cells","volume":"99","author":"Yang","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/jpet.119.256560_bib60","first-page":"690","article-title":"Tetrabenazine (xenazine), an FDA-approved treatment option for Huntington\u2019s disease-related chorea","volume":"33","author":"Yero","year":"2008","journal-title":"P&T"},{"key":"10.1124\/jpet.119.256560_bib61","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.str.2012.04.015","article-title":"Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain","volume":"20","author":"Yuchi","year":"2012","journal-title":"Structure"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524268750?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524268750?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/jpet.119.256560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T13:57:39Z","timestamp":1739973459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356524268750"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S0022356524268750"],"URL":"https:\/\/doi.org\/10.1124\/jpet.119.256560","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tetrabenazine Facilitates Exocytosis by Enhancing Calcium-Induced Calcium Release through Ryanodine Receptors","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/jpet.119.256560","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by The American Society for Pharmacology and Experimental Therapeutics","name":"copyright","label":"Copyright"}]}}