{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:55:26Z","timestamp":1793199326674,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1124\/jpet.122.001250","type":"journal-article","created":{"date-parts":[[2022,6,28]],"date-time":"2022-06-28T18:00:08Z","timestamp":1656439208000},"page":"72-78","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Mitochondrial microRNAs Are Dysregulated in Patients with Fabry Disease"],"prefix":"10.1016","volume":"384","author":[{"given":"Jessica","family":"Gambardella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella","family":"Fiordelisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Sorriento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Cerasuolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonietta","family":"Buonaiuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Avvisato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahimeh","family":"Varzideh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Riccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7231-375X","authenticated-orcid":false,"given":"Gaetano","family":"Santulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Iaccarino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1124\/jpet.122.001250_bib1","doi-asserted-by":"crossref","first-page":"E799","DOI":"10.1152\/ajpendo.00448.2009","article-title":"The microRNA miR-696 regulates PGC-1alpha in mouse skeletal muscle in response to physical activity","volume":"298","author":"Aoi","year":"2010","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1124\/jpet.122.001250_bib2","doi-asserted-by":"crossref","first-page":"12581","DOI":"10.1523\/JNEUROSCI.3338-08.2008","article-title":"MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons","volume":"28","author":"Aschrafi","year":"2008","journal-title":"J Neurosci"},{"key":"10.1124\/jpet.122.001250_bib3","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3390\/ijms22010206","article-title":"Fabry Disease Therapy: State-of-the-Art and Current Challenges","volume":"22","author":"Azevedo","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1124\/jpet.122.001250_bib4","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.33594\/000000077","article-title":"Enzyme Replacement Therapy Clears Gb3 Deposits from a Podocyte Cell Culture Model of Fabry Disease but Fails to Restore Altered Cellular Signaling","volume":"52","author":"Braun","year":"2019","journal-title":"Cell Physiol Biochem"},{"key":"10.1124\/jpet.122.001250_bib5","doi-asserted-by":"crossref","first-page":"27333","DOI":"10.18632\/oncotarget.25542","article-title":"A pilot study of circulating microRNAs as potential biomarkers of Fabry disease","volume":"9","author":"Cammarata","year":"2018","journal-title":"Oncotarget"},{"key":"10.1124\/jpet.122.001250_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0055194","article-title":"Suppression of mitochondrial electron transport chain function in the hypoxic human placenta: a role for miRNA-210 and protein synthesis inhibition","volume":"8","author":"Colleoni","year":"2013","journal-title":"PLoS One"},{"key":"10.1124\/jpet.122.001250_bib7","first-page":"48","article-title":"Non-Coding RNAs as Prognostic Biomarkers: A miRNA Signature Specific for Aggressive Early-Stage Lung Adenocarcinomas","volume":"6","author":"Dama","year":"2020","journal-title":"Noncoding RNA"},{"key":"10.1124\/jpet.122.001250_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0065-2423(09)49003-6","article-title":"Biochemical basis of Fabry disease with emphasis on mitochondrial function and protein trafficking","volume":"49","author":"Das","year":"2009","journal-title":"Adv Clin Chem"},{"key":"10.1124\/jpet.122.001250_bib9","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1161\/CIRCRESAHA.112.267732","article-title":"Nuclear miRNA regulates the mitochondrial genome in the heart","volume":"110","author":"Das","year":"2012","journal-title":"Circ Res"},{"key":"10.1124\/jpet.122.001250_bib10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3390\/diseases4040031","article-title":"Mitochondrial Dysfunction in Lysosomal Storage Disorders","volume":"4","author":"de la Mata","year":"2016","journal-title":"Diseases"},{"key":"10.1124\/jpet.122.001250_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2021.166208","article-title":"Mitochondrial function, dynamics and quality control in the pathophysiology of HFpEF","volume":"1867","author":"Del Campo","year":"2021","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"10.1124\/jpet.122.001250_bib12","first-page":"55","article-title":"MicroRNAs as Potential Biomarkers in Pituitary Adenomas","volume":"7","author":"Donati","year":"2021","journal-title":"Noncoding RNA"},{"key":"10.1124\/jpet.122.001250_bib13","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1186\/s13054-021-03731-1","article-title":"Role of endothelial miR-24 in COVID-19 cerebrovascular events","volume":"25","author":"Gambardella","year":"2021","journal-title":"Crit Care"},{"key":"10.1124\/jpet.122.001250_bib14","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.healun.2021.12.008","article-title":"Glycation of ryanodine receptor in circulating lymphocytes predicts the response to cardiac resynchronization therapy","volume":"41","author":"Gambardella","year":"2022","journal-title":"J Heart Lung Transplant"},{"key":"10.1124\/jpet.122.001250_bib15","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1161\/HYPERTENSIONAHA.120.15130","article-title":"Role of Endothelial G Protein-Coupled Receptor Kinase 2 in Angioedema","volume":"76","author":"Gambardella","year":"2020","journal-title":"Hypertension"},{"key":"10.1124\/jpet.122.001250_bib125","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3390\/biomedicines8080277","article-title":"Arginine and Endothelial Function","volume":"8","author":"Gambardella","year":"2020","journal-title":"Biomedicines"},{"key":"10.1124\/jpet.122.001250_bib16","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1750-1172-5-30","article-title":"Fabry disease","volume":"5","author":"Germain","year":"2010","journal-title":"Orphanet J Rare Dis"},{"key":"10.1124\/jpet.122.001250_bib17","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1056\/NEJMoa1510198","article-title":"Treatment of Fabry\u2019s Disease with the Pharmacologic Chaperone Migalastat","volume":"375","author":"Germain","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1124\/jpet.122.001250_bib18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3389\/fncel.2017.00149","article-title":"Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation","volume":"11","author":"Goubert","year":"2017","journal-title":"Front Cell Neurosci"},{"key":"10.1124\/jpet.122.001250_bib19","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.3390\/cells10061552","article-title":"Impact of Aldosterone on the Failing Myocardium: Insights from Mitochondria and Adrenergic Receptors Signaling and Function","volume":"10","author":"Guitart-Mampel","year":"2021","journal-title":"Cells"},{"key":"10.1124\/jpet.122.001250_bib20","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1086\/316953","article-title":"Fabry disease: preclinical studies demonstrate the effectiveness of alpha-galactosidase A replacement in enzyme-deficient mice","volume":"68","author":"Ioannou","year":"2001","journal-title":"Am J Hum Genet"},{"key":"10.1124\/jpet.122.001250_bib21","first-page":"39","article-title":"Functional Role of miR-155 in the Pathogenesis of Diabetes Mellitus and Its Complications","volume":"7","author":"Jankauskas","year":"2021","journal-title":"Noncoding RNA"},{"key":"10.1124\/jpet.122.001250_bib22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1042\/bse0470069","article-title":"Regulation of mitochondrial biogenesis","volume":"47","author":"Jornayvaz","year":"2010","journal-title":"Essays Biochem"},{"key":"10.1124\/jpet.122.001250_bib23","first-page":"8","article-title":"MicroRNAs as Candidate Biomarkers for Alzheimer\u2019s Disease","volume":"7","author":"Kanach","year":"2021","journal-title":"Noncoding RNA"},{"key":"10.1124\/jpet.122.001250_bib24","doi-asserted-by":"crossref","first-page":"983","DOI":"10.3390\/cells11060983","article-title":"Functional Role of microRNAs in Regulating Cardiomyocyte Death","volume":"11","author":"Kansakar","year":"2022","journal-title":"Cells"},{"key":"10.1124\/jpet.122.001250_bib26","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4161\/rna.6.1.7534","article-title":"MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis","volume":"6","author":"Kren","year":"2009","journal-title":"RNA Biol"},{"key":"10.1124\/jpet.122.001250_bib28","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.3390\/genes12071057","article-title":"Urinary Extracellular Vesicles and Their miRNA Cargo in Patients with Fabry Nephropathy","volume":"12","author":"Levstek","year":"2021","journal-title":"Genes (Basel)"},{"key":"10.1124\/jpet.122.001250_bib29","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1002\/jcb.24004","article-title":"Control of mitochondrial activity by miRNAs","volume":"113","author":"Li","year":"2012","journal-title":"J Cell Biochem"},{"key":"10.1124\/jpet.122.001250_bib30","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ymgme.2004.01.011","article-title":"Fabry disease: reduced activities of respiratory chain enzymes with decreased levels of energy-rich phosphates in fibroblasts","volume":"82","author":"L\u00fccke","year":"2004","journal-title":"Mol Genet Metab"},{"key":"10.1124\/jpet.122.001250_bib31","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.3390\/genes12081184","article-title":"MiRNA Let-7a and Let-7d Are Induced by Globotriaosylceramide via NF-kB Activation in Fabry Disease","volume":"12","author":"Maier","year":"2021","journal-title":"Genes (Basel)"},{"key":"10.1124\/jpet.122.001250_bib32","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.3390\/cells9071621","article-title":"miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting \u03b2-Arrestin 1","volume":"9","author":"Matarese","year":"2020","journal-title":"Cells"},{"key":"10.1124\/jpet.122.001250_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagen.2019.129437","article-title":"Progress in the understanding and treatment of Fabry disease","volume":"1864","author":"Miller","year":"2020","journal-title":"Biochim Biophys Acta, Gen Subj"},{"key":"10.1124\/jpet.122.001250_bib34","first-page":"9","article-title":"miR-24 Targets the Transmembrane Glycoprotein Neuropilin-1 in Human Brain Microvascular Endothelial Cells","volume":"7","author":"Mone","year":"2021","journal-title":"Noncoding RNA"},{"key":"10.1124\/jpet.122.001250_bib126","doi-asserted-by":"crossref","unstructured":"Mone P, Lombardi A, Kansakar U, Varzideh F, Jankauskas SS, Pansini A, De Gennaro S, Famiglietti M, Macina G, Frullone S et al. (2022) Empagliflozin improves the microRNA signature of endothelial dysfunction in patients with HFpEF and diabetes. J Pharmacol Exp Ther, in press DOI: 10.1124\/jpet.121.001251.","DOI":"10.1124\/jpet.121.001251"},{"key":"10.1124\/jpet.122.001250_bib35","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1007\/s12325-019-01061-x","article-title":"Symptoms and Quality of Life in Patients with Fabry Disease: Results from an International Patient Survey","volume":"36","author":"Morand","year":"2019","journal-title":"Adv Ther"},{"key":"10.1124\/jpet.122.001250_bib36","first-page":"436","article-title":"Mitochondrial Bioenergetics and Dynamism in the Failing Heart","volume":"11","author":"Morciano","year":"2021","journal-title":"Life (Basel)"},{"key":"10.1124\/jpet.122.001250_bib37","doi-asserted-by":"crossref","first-page":"e162","DOI":"10.7717\/peerj.162","article-title":"MiR-184 regulates insulin secretion through repression of Slc25a22","volume":"1","author":"Morita","year":"2013","journal-title":"PeerJ"},{"key":"10.1124\/jpet.122.001250_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/7b2c04df-8592-4fb7-8608-3039db28b504","article-title":"Globotriaosylsphingosine accumulation and not alpha-galactosidase-A deficiency causes endothelial dysfunction in Fabry disease","volume":"7","author":"Namdar","year":"2012","journal-title":"PLoS One"},{"key":"10.1124\/jpet.122.001250_bib39","doi-asserted-by":"crossref","first-page":"H710","DOI":"10.1152\/ajpheart.00538.2017","article-title":"miR-21-5p regulates mitochondrial respiration and lipid content in H9C2 cells","volume":"316","author":"Nasci","year":"2019","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/jpet.122.001250_bib40","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/978-3-319-22380-3_5","article-title":"Mechanistic Role of MicroRNAs in Coupling Lipid Metabolism and Atherosclerosis","volume":"887","author":"Nov\u00e1k","year":"2015","journal-title":"Adv Exp Med Biol"},{"key":"10.1124\/jpet.122.001250_bib41","doi-asserted-by":"crossref","first-page":"H33","DOI":"10.1152\/ajpheart.00341.2016","article-title":"Role of microRNA in metabolic shift during heart failure","volume":"312","author":"Pinti","year":"2017","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/jpet.122.001250_bib42","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.ymgme.2012.08.003","article-title":"Enzyme replacement therapy in patients with Fabry disease: state of the art and review of the literature","volume":"107","author":"Pisani","year":"2012","journal-title":"Mol Genet Metab"},{"key":"10.1124\/jpet.122.001250_bib44","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1038\/s41431-020-0677-x","article-title":"Switch from enzyme replacement therapy to oral chaperone migalastat for treating fabry disease: real-life data","volume":"28","author":"Riccio","year":"2020","journal-title":"Eur J Hum Genet"},{"key":"10.1124\/jpet.122.001250_bib45","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ymgme.2017.09.004","article-title":"Contribution of inflammatory pathways to Fabry disease pathogenesis","volume":"122","author":"Rozenfeld","year":"2017","journal-title":"Mol Genet Metab"},{"key":"10.1124\/jpet.122.001250_bib46","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1038\/s41419-021-04438-5","article-title":"Circulating miR-184 is a potential predictive biomarker of cardiac damage in Anderson-Fabry disease","volume":"12","author":"Salamon","year":"2021","journal-title":"Cell Death Dis"},{"key":"10.1124\/jpet.122.001250_bib47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-319-22671-2_1","article-title":"Exploiting microRNA Specificity and Selectivity: Paving a Sustainable Path Towards Precision Medicine","volume":"888","author":"Santulli","year":"2015","journal-title":"Adv Exp Med Biol"},{"key":"10.1124\/jpet.122.001250_bib48","series-title":"MicroRNA: From Molecular Biology to Clinical Practice","author":"Santulli","year":"2016"},{"key":"10.1124\/jpet.122.001250_bib49","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/j.amjcard.2010.12.006","article-title":"G protein-coupled receptor kinase 2 in patients with acute myocardial infarction","volume":"107","author":"Santulli","year":"2011","journal-title":"Am J Cardiol"},{"key":"10.1124\/jpet.122.001250_bib50","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fphys.2014.00015","article-title":"Atrial fibrillation and microRNAs","volume":"5","author":"Santulli","year":"2014","journal-title":"Front Physiol"},{"key":"10.1124\/jpet.122.001250_bib51","doi-asserted-by":"crossref","first-page":"11389","DOI":"10.1073\/pnas.1513047112","article-title":"Mitochondrial calcium overload is a key determinant in heart failure","volume":"112","author":"Santulli","year":"2015","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/jpet.122.001250_bib52","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.2217\/pgs.14.76","article-title":"Functional role of miRNA in cardiac resynchronization therapy","volume":"15","author":"Sardu","year":"2014","journal-title":"Pharmacogenomics"},{"key":"10.1124\/jpet.122.001250_bib53","first-page":"413","article-title":"Comparative studies on the anticonvulsant effectiveness of nootropic drugs in kindled rats","volume":"49","author":"Schmidt","year":"1990","journal-title":"Biomed Biochim Acta"},{"key":"10.1124\/jpet.122.001250_bib54","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s11897-022-00539-0","article-title":"Mitochondria as Therapeutic Targets in Heart Failure","volume":"19","author":"Schwemmlein","year":"2022","journal-title":"Curr Heart Fail Rep"},{"key":"10.1124\/jpet.122.001250_bib55","doi-asserted-by":"crossref","first-page":"8080","DOI":"10.3390\/ijms21218080","article-title":"Biomarkers in Anderson-Fabry Disease","volume":"21","author":"Simonetta","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1124\/jpet.122.001250_bib57","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.3390\/cells8121475","article-title":"Mitochondrial MiRNA in Cardiovascular Function and Disease","volume":"8","author":"Song","year":"2019","journal-title":"Cells"},{"key":"10.1124\/jpet.122.001250_bib58","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3390\/ijms22031331","article-title":"The Cardiovascular Phenotype in Fabry Disease: New Findings in the Research Field","volume":"22","author":"Sorriento","year":"2021","journal-title":"Int J Mol Sci"},{"key":"10.1124\/jpet.122.001250_bib59","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s10741-018-9686-z","article-title":"Influence of exercise on oxidative stress in patients with heart failure","volume":"23","author":"Sties","year":"2018","journal-title":"Heart Fail Rev"},{"key":"10.1124\/jpet.122.001250_bib60","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s12872-017-0549-7","article-title":"MiR-486 regulates cardiomyocyte apoptosis by p53-mediated BCL-2 associated mitochondrial apoptotic pathway","volume":"17","author":"Sun","year":"2017","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1124\/jpet.122.001250_bib61","doi-asserted-by":"crossref","first-page":"551","DOI":"10.2147\/TCRM.S247814","article-title":"Diagnosis and Screening of Patients with Fabry Disease","volume":"16","author":"Vardarli","year":"2020","journal-title":"Ther Clin Risk Manag"},{"key":"10.1124\/jpet.122.001250_bib127","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.863238","article-title":"Cardiac Remodeling After Myocardial Infarction: Functional Contribution of microRNAs to Inflammation and Fibrosis","volume":"9","author":"Varzideh","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1124\/jpet.122.001250_bib62","article-title":"Mitochondria Associated MicroRNA Expression Profiling of Heart Failure","volume":"2017","author":"Wang","year":"2017","journal-title":"BioMed Res Int"},{"key":"10.1124\/jpet.122.001250_bib63","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/1750-1172-8-116","article-title":"Fibrosis: a key feature of Fabry disease with potential therapeutic implications","volume":"8","author":"Weidemann","year":"2013","journal-title":"Orphanet J Rare Dis"},{"key":"10.1124\/jpet.122.001250_bib64","doi-asserted-by":"crossref","first-page":"15277","DOI":"10.1038\/s41598-019-51805-6","article-title":"Circulating microRNAs in Fabry Disease","volume":"9","author":"Xiao","year":"2019","journal-title":"Sci Rep"},{"key":"10.1124\/jpet.122.001250_bib65","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0014356","article-title":"miR-17* suppresses tumorigenicity of prostate cancer by inhibiting mitochondrial antioxidant enzymes","volume":"5","author":"Xu","year":"2010","journal-title":"PLoS One"},{"key":"10.1124\/jpet.122.001250_bib66","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/FJC.0000000000001081","article-title":"Regulation of Mitochondrial Function by Noncoding RNAs in Heart Failure and Its Application in Diagnosis and Treatment","volume":"78","author":"Yang","year":"2021","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1124\/jpet.122.001250_bib67","article-title":"MicroRNAs Regulating Mitochondrial Function in Cardiac Diseases","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Pharmacol"},{"key":"10.1124\/jpet.122.001250_bib68","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.cell.2014.05.047","article-title":"MicroRNA directly enhances mitochondrial translation during muscle differentiation","volume":"158","author":"Zhang","year":"2014","journal-title":"Cell"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524003744?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524003744?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/jpet.122.001250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T13:17:19Z","timestamp":1739971039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356524003744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":67,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S0022356524003744"],"URL":"https:\/\/doi.org\/10.1124\/jpet.122.001250","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitochondrial microRNAs Are Dysregulated in Patients with Fabry Disease","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/jpet.122.001250","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by The American Society for Pharmacology and Experimental Therapeutics","name":"copyright","label":"Copyright"}]}}