{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:14:00Z","timestamp":1790036040432,"version":"4.0.1"},"reference-count":63,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":458,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1124\/jpet.122.001480","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T23:35:30Z","timestamp":1683761730000},"page":"4-14","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Antinociceptive Effects of an Anti-CGRP Antibody in Rat Models of Colon-Bladder Cross-Organ Sensitization"],"prefix":"10.1016","volume":"387","author":[{"given":"Ehsan","family":"Noor-Mohammadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey O.","family":"Ligon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly D.","family":"Mackenzie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Stratton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara J.","family":"Shnider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverley","family":"Greenwood-Van Meerveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1124\/jpet.122.001480_bib1","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.juro.2011.03.132","article-title":"Prevalence of symptoms of bladder pain syndrome\/interstitial cystitis among adult females in the United States","volume":"186","author":"Berry","year":"2011","journal-title":"J Urol"},{"key":"10.1124\/jpet.122.001480_bib2","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1177\/0333102420983282","article-title":"Migraine therapeutics differentially modulate the CGRP pathway","volume":"41","author":"Bhakta","year":"2021","journal-title":"Cephalalgia"},{"key":"10.1124\/jpet.122.001480_bib3","doi-asserted-by":"crossref","first-page":"G658","DOI":"10.1152\/ajpgi.00585.2005","article-title":"Convergence of sensory pathways in the development of somatic and visceral hypersensitivity","volume":"291","author":"Bielefeldt","year":"2006","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1124\/jpet.122.001480_bib4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12876-014-0189-7","article-title":"Intestinal permeability\u2014a new target for disease prevention and therapy","volume":"14","author":"Bischoff","year":"2014","journal-title":"BMC Gastroenterol"},{"key":"10.1124\/jpet.122.001480_bib5","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/313054a0","article-title":"Calcitonin gene-related peptide is a potent vasodilator","volume":"313","author":"Brain","year":"1985","journal-title":"Nature"},{"key":"10.1124\/jpet.122.001480_bib6","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1365-2982.2012.01921.x","article-title":"Intestinal barrier function in health and gastrointestinal disease","volume":"24","author":"Camilleri","year":"2012","journal-title":"Neurogastroenterol Motil"},{"key":"10.1124\/jpet.122.001480_bib7","doi-asserted-by":"crossref","first-page":"3516","DOI":"10.1111\/bph.14396","article-title":"Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome","volume":"175","author":"Ceuleers","year":"2018","journal-title":"Br J Pharmacol"},{"key":"10.1124\/jpet.122.001480_bib8","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jocn.2009.03.042","article-title":"Expression of calcitonin gene-related peptide in anterior and posterior horns of the spinal cord after brachial plexus injury","volume":"17","author":"Chen","year":"2010","journal-title":"J Clin Neurosci"},{"key":"10.1124\/jpet.122.001480_bib9","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.pain.2006.09.023","article-title":"Convergence of bladder and colon sensory innervation occurs at the primary afferent level","volume":"128","author":"Christianson","year":"2007","journal-title":"Pain"},{"key":"10.1124\/jpet.122.001480_bib10","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/164_2018_130","article-title":"CGRP receptor signalling pathways","volume":"255","author":"Cottrell","year":"2019","journal-title":"Handb Exp Pharmacol"},{"key":"10.1124\/jpet.122.001480_bib11","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/mi.2014.82","article-title":"TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP","volume":"8","author":"de Jong","year":"2015","journal-title":"Mucosal Immunol"},{"key":"10.1124\/jpet.122.001480_bib12","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1136\/gut.2005.064063","article-title":"Interactive involvement of brain derived neurotrophic factor, nerve growth factor, and calcitonin gene related peptide in colonic hypersensitivity in the rat","volume":"55","author":"Delafoy","year":"2006","journal-title":"Gut"},{"key":"10.1124\/jpet.122.001480_bib13","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s10194-019-0974-3","article-title":"Therapeutic novelties in migraine: new drugs, new hope?","volume":"20","author":"Do","year":"2019","journal-title":"J Headache Pain"},{"key":"10.1124\/jpet.122.001480_bib14","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/0168-0102(92)90018-8","article-title":"Distribution and origin of extrinsic nerve fibers containing calcitonin gene-related peptide, substance P and galanin in the rat upper rectum","volume":"15","author":"Domoto","year":"1992","journal-title":"Neurosci Res"},{"key":"10.1124\/jpet.122.001480_bib15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0928-4257(93)90017-N","article-title":"Involvement of calcitonin gene-related peptide in rat experimental colitis","volume":"87","author":"Evangelista","year":"1993","journal-title":"J Physiol Paris"},{"key":"10.1124\/jpet.122.001480_bib16","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1053\/j.gastro.2010.03.003","article-title":"Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms","volume":"138","author":"Gosselin","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1124\/jpet.122.001480_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.urology.2018.02.034","article-title":"Preclinical animal studies of intravesical recombinant human proteoglycan 4 as a novel potential therapy for diseases resulting from increased bladder permeability","volume":"116","author":"Greenwood-Van Meerveld","year":"2018","journal-title":"Urology"},{"key":"10.1124\/jpet.122.001480_bib18","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.juro.2015.02.2944","article-title":"Mechanisms of visceral organ crosstalk: importance of alterations in permeability in rodent models","volume":"194","author":"Greenwood-Van Meerveld","year":"2015","journal-title":"J Urol"},{"key":"10.1124\/jpet.122.001480_bib19","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3844\/ajptsp.2006.54.59","article-title":"CPI-1189 protects against dextran sulfate sodium-induced colitis in mice","volume":"1","author":"Greenwood-Van Meerveld","year":"2006","journal-title":"Am J Pharmacol Toxicol"},{"key":"10.1124\/jpet.122.001480_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2020.590871","article-title":"Experimentally induced bladder permeability evokes bladder afferent hypersensitivity in the absence of inflammation","volume":"14","author":"Grundy","year":"2020","journal-title":"Front Neurosci"},{"key":"10.1124\/jpet.122.001480_bib21","series-title":"Interstitial Cystitis","first-page":"29","article-title":"Epidemiology of Interstitial Cystitis: 2","author":"Held","year":"1990"},{"key":"10.1124\/jpet.122.001480_bib22","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1002\/cne.25403","article-title":"Quantification of CGRP-immunoreactive myenteric neurons in mouse colon","volume":"530","author":"Hibberd","year":"2022","journal-title":"J Comp Neurol"},{"key":"10.1124\/jpet.122.001480_bib23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/978-1-4939-0897-4_9","article-title":"Neuropeptides and the microbiota-gut-brain axis","volume":"817","author":"Holzer","year":"2014","journal-title":"Adv Exp Med Biol"},{"key":"10.1124\/jpet.122.001480_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00726-011-1161-2","article-title":"Modulation of immune responses by the neuropeptide CGRP","volume":"45","author":"Holzmann","year":"2013","journal-title":"Amino Acids"},{"key":"10.1124\/jpet.122.001480_bib25","first-page":"563","article-title":"Increased bladder permeability in interstitial cystitis\/painful bladder syndrome","volume":"4","author":"Hurst","year":"2015","journal-title":"Transl Androl Urol"},{"key":"10.1124\/jpet.122.001480_bib26","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/164_2016_120","article-title":"Critical evaluation of animal models of gastrointestinal disorders","volume":"239","author":"Johnson","year":"2017","journal-title":"Handb Exp Pharmacol"},{"key":"10.1124\/jpet.122.001480_bib27","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0304-3959(01)00275-5","article-title":"A new model of visceral pain and referred hyperalgesia in the mouse","volume":"92","author":"Laird","year":"2001","journal-title":"Pain"},{"key":"10.1124\/jpet.122.001480_bib28","doi-asserted-by":"crossref","first-page":"F242","DOI":"10.1152\/ajprenal.00307.2001","article-title":"Bladder permeability barrier: recovery from selective injury of surface epithelial cells","volume":"283","author":"Lavelle","year":"2002","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/jpet.122.001480_bib29","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1007\/s10620-012-2406-y","article-title":"Calcitonin gene-related peptide is a promising marker in ulcerative colitis","volume":"58","author":"Li","year":"2013","journal-title":"Dig Dis Sci"},{"key":"10.1124\/jpet.122.001480_bib30","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.gtc.2005.02.011","article-title":"Definition and classification of irritable bowel syndrome: current consensus and controversies","volume":"34","author":"Longstreth","year":"2005","journal-title":"Gastroenterol Clin North Am"},{"key":"10.1124\/jpet.122.001480_bib31","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1053\/j.gastro.2005.11.061","article-title":"Functional bowel disorders","volume":"130","author":"Longstreth","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1124\/jpet.122.001480_bib32","doi-asserted-by":"crossref","first-page":"548","DOI":"10.3390\/ijms19020548","article-title":"The influence of inflammation and nerve damage on the neurochemical characterization of calcitonin gene-related peptide-like immunoreactive (CGRP-LI) neurons in the enteric nervous system of the porcine descending colon","volume":"19","author":"Makowska","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1124\/jpet.122.001480_bib33","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3390\/toxins9030098","article-title":"The influence of low doses of zearalenone and T-2 toxin on calcitonin gene related peptide-like immunoreactive (CGRP-LI) neurons in the ENS of the porcine descending colon","volume":"9","author":"Makowska","year":"2017","journal-title":"Toxins (Basel)"},{"key":"10.1124\/jpet.122.001480_bib34","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.neuroscience.2007.07.053","article-title":"Neural mechanisms of pelvic organ cross-sensitization","volume":"149","author":"Malykhina","year":"2007","journal-title":"Neuroscience"},{"key":"10.1124\/jpet.122.001480_bib35","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1365-2982.2006.00807.x","article-title":"Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk","volume":"18","author":"Malykhina","year":"2006","journal-title":"Neurogastroenterol Motil"},{"key":"10.1124\/jpet.122.001480_bib36","doi-asserted-by":"crossref","first-page":"7149","DOI":"10.1523\/JNEUROSCI.0576-17.2017","article-title":"Selective inhibition of trigeminovascular neurons by fremanezumab: a humanized monoclonal anti-CGRP antibody","volume":"37","author":"Melo-Carrillo","year":"2017","journal-title":"J Neurosci"},{"key":"10.1124\/jpet.122.001480_bib37","doi-asserted-by":"crossref","first-page":"10587","DOI":"10.1523\/JNEUROSCI.2211-17.2017","article-title":"Fremanezumab-A humanized monoclonal anti-CGRP antibody-inhibits thinly myelinated (A\u03b4) but not unmyelinated (C) meningeal nociceptors","volume":"37","author":"Melo-Carrillo","year":"2017","journal-title":"J Neurosci"},{"key":"10.1124\/jpet.122.001480_bib38","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1046\/j.1365-2982.1998.00111.x","article-title":"Distribution of calcitonin gene-related peptide, somatostatin, substance P and vasoactive intestinal polypeptide in experimental colitis in rats","volume":"10","author":"Miampamba","year":"1998","journal-title":"Neurogastroenterol Motil"},{"key":"10.1124\/jpet.122.001480_bib39","doi-asserted-by":"crossref","first-page":"G1622","DOI":"10.1152\/ajpgi.00080.2007","article-title":"Corticosteroid receptor-mediated mechanisms in the amygdala regulate anxiety and colonic sensitivity","volume":"292","author":"Myers","year":"2007","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1124\/jpet.122.001480_bib40","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1124\/jpet.121.000731","article-title":"A monoclonal anti-calcitonin gene-related peptide antibody decreases stress-induced colonic hypersensitivity","volume":"379","author":"Noor-Mohammadi","year":"2021","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/jpet.122.001480_bib41","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.expneurol.2010.05.012","article-title":"Experimental colitis triggers the release of substance P and calcitonin gene-related peptide in the urinary bladder via TRPV1 signaling pathways","volume":"225","author":"Pan","year":"2010","journal-title":"Exp Neurol"},{"key":"10.1124\/jpet.122.001480_bib42","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1007\/s00404-017-4364-2","article-title":"Etiology, pathophysiology and biomarkers of interstitial cystitis\/painful bladder syndrome","volume":"295","author":"Patnaik","year":"2017","journal-title":"Arch Gynecol Obstet"},{"key":"10.1124\/jpet.122.001480_bib43","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1053\/j.gastro.2005.03.008","article-title":"A model of neural cross-talk and irritation in the pelvis: implications for the overlap of chronic pelvic pain disorders","volume":"128","author":"Pezzone","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1124\/jpet.122.001480_bib44","first-page":"G191","article-title":"Calcitonin gene-related peptide in viscerosensitive response to colorectal distension in rats","volume":"273","author":"Plourde","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1124\/jpet.122.001480_bib45","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.expneurol.2006.12.024","article-title":"Up-regulation of calcitonin gene-related peptide and receptor tyrosine kinase TrkB in rat bladder afferent neurons following TNBS colitis","volume":"204","author":"Qiao","year":"2007","journal-title":"Exp Neurol"},{"key":"10.1124\/jpet.122.001480_bib46","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.expneurol.2009.04.026","article-title":"Colitis induces calcitonin gene-related peptide expression and Akt activation in rat primary afferent pathways","volume":"219","author":"Qiao","year":"2009","journal-title":"Exp Neurol"},{"key":"10.1124\/jpet.122.001480_bib47","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0022-3565(24)37636-0","article-title":"Calcitonin gene-related peptide mediates the protective effect of sensory nerves in a model of colonic injury","volume":"286","author":"Reinshagen","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/jpet.122.001480_bib48","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/304129a0","article-title":"Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing","volume":"304","author":"Rosenfeld","year":"1983","journal-title":"Nature"},{"key":"10.1124\/jpet.122.001480_bib49","doi-asserted-by":"crossref","first-page":"R1191","DOI":"10.1152\/ajpregu.00411.2007","article-title":"Organ cross talk modulates pelvic pain","volume":"293","author":"Rudick","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1124\/jpet.122.001480_bib50","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.neulet.2016.02.029","article-title":"Acetylsalicylic acid-induced changes in the chemical coding of extrinsic sensory neurons supplying the prepyloric area of the porcine stomach","volume":"617","author":"Rytel","year":"2016","journal-title":"Neurosci Lett"},{"key":"10.1124\/jpet.122.001480_bib51","first-page":"1910","article-title":"The epidemiology of irritable bowel syndrome in North America: a systematic review","volume":"97","author":"Saito","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1124\/jpet.122.001480_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.autneu.2020.102697","article-title":"Morphological and neurochemical characterisation of anterogradely labelled spinal sensory and autonomic nerve endings in the mouse bladder","volume":"227","author":"Sharma","year":"2020","journal-title":"Auton Neurosci"},{"key":"10.1124\/jpet.122.001480_bib53","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1016\/0016-5085(87)90450-1","article-title":"Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats","volume":"93","author":"Sternini","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1124\/jpet.122.001480_bib54","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1744-8069-5-54","article-title":"NMDA receptor subunit expression and PAR2 receptor activation in colospinal afferent neurons (CANs) during inflammation induced visceral hypersensitivity","volume":"5","author":"Suckow","year":"2009","journal-title":"Mol Pain"},{"key":"10.1124\/jpet.122.001480_bib55","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-1-4899-0744-8_3","article-title":"Occurrence and distribution of substance P- and CGRP-containing nerve fibers in gastric mucosa: species differences","volume":"298","author":"Sundler","year":"1991","journal-title":"Adv Exp Med Biol"},{"key":"10.1124\/jpet.122.001480_bib56","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s10620-007-9848-7","article-title":"Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis","volume":"53","author":"Thompson","year":"2008","journal-title":"Dig Dis Sci"},{"key":"10.1124\/jpet.122.001480_bib57","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1159\/000147227","article-title":"Calcitonin gene-related peptide-like immunoreactivity in the human small intestine","volume":"143","author":"Timmermans","year":"1992","journal-title":"Acta Anat (Basel)"},{"key":"10.1124\/jpet.122.001480_bib58","doi-asserted-by":"crossref","first-page":"F1478","DOI":"10.1152\/ajprenal.00395.2005","article-title":"Colonic irritation in the rat sensitizes urinary bladder afferents to mechanical and chemical stimuli: an afferent origin of pelvic organ cross-sensitization","volume":"290","author":"Ustinova","year":"2006","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/jpet.122.001480_bib59","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jphs.2017.12.012","article-title":"Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice: Links to calcitonin gene-related peptide and substance P","volume":"136","author":"Utsumi","year":"2018","journal-title":"J Pharmacol Sci"},{"key":"10.1124\/jpet.122.001480_bib60","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/bcp.12669","article-title":"Calcitonin gene-related peptide in the joint: contributions to pain and inflammation","volume":"80","author":"Walsh","year":"2015","journal-title":"Br J Clin Pharmacol"},{"key":"10.1124\/jpet.122.001480_bib61","doi-asserted-by":"crossref","first-page":"R1592","DOI":"10.1152\/ajpregu.00455.2006","article-title":"Cross-organ interactions between reproductive, gastrointestinal, and urinary tracts: modulation by estrous stage and involvement of the hypogastric nerve","volume":"291","author":"Winnard","year":"2006","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1124\/jpet.122.001480_bib62","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/ar.20577","article-title":"Calcitonin gene-related peptide: a marker for putative primary afferent neurons in the pig small intestinal myenteric plexus?","volume":"290","author":"Wolf","year":"2007","journal-title":"Anat Rec (Hoboken)"},{"key":"10.1124\/jpet.122.001480_bib63","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nrgastro.2011.83","article-title":"New insights into visceral hypersensitivity--clinical implications in IBS","volume":"8","author":"Zhou","year":"2011","journal-title":"Nat Rev Gastroenterol Hepatol"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524170863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524170863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/jpet.122.001480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T13:30:57Z","timestamp":1739971857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356524170863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S0022356524170863"],"URL":"https:\/\/doi.org\/10.1124\/jpet.122.001480","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antinociceptive Effects of an Anti-CGRP Antibody in Rat Models of Colon-Bladder Cross-Organ Sensitization","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/jpet.122.001480","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by The Author(s)","name":"copyright","label":"Copyright"}]}}