{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:13:49Z","timestamp":1756462429809,"version":"3.38.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":245,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1124\/jpet.123.001664","type":"journal-article","created":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T22:40:18Z","timestamp":1689288018000},"page":"136-149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Recovery from Traumatic Brain Injury Is Nociceptin\/Orphanin FQ Peptide Receptor Genotype-, Sex-, and Injury Severity-Dependent"],"prefix":"10.1016","volume":"389","author":[{"given":"Omar N.","family":"Al Yacoub","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hibah O.","family":"Awwad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly M.","family":"Standifer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1124\/jpet.123.001664_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2021.107982","article-title":"Therapeutic potential of nociceptin\/orphanin FQ peptide (NOP) receptor modulators for treatment of traumatic brain injury, traumatic stress, and their co-morbidities","volume":"231","author":"Al Yacoub","year":"2022","journal-title":"Pharmacol Ther"},{"key":"10.1124\/jpet.123.001664_bib2","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1111\/j.1582-4934.2010.01164.x","article-title":"Clinical characteristics and pathophysiological mechanisms of focal and diffuse traumatic brain injury","volume":"14","author":"Andriessen","year":"2010","journal-title":"J Cell Mol Med"},{"key":"10.1124\/jpet.123.001664_bib3","doi-asserted-by":"crossref","first-page":"H477","DOI":"10.1152\/ajpheart.2000.278.2.H477","article-title":"Relationship between nociceptin\/orphanin FQ and cerebral hemodynamics after hypoxia-ischemia in piglets","volume":"278","author":"Armstead","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/jpet.123.001664_bib4","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1089\/neu.2000.17.751","article-title":"Role of nociceptin\/orphanin FQ in age-dependent cerebral hemodynamic effects of brain injury","volume":"17","author":"Armstead","year":"2000","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib5","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1177\/153537020222701103","article-title":"Role of nociceptin\/orphanin FQ in the physiologic and pathologic control of the cerebral circulation","volume":"227","author":"Armstead","year":"2002","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1124\/jpet.123.001664_bib6","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/978-1-4939-3816-2_31","article-title":"Detecting behavioral deficits post traumatic brain injury in rats","volume":"1462","author":"Awwad","year":"2016","journal-title":"Methods Mol Biol"},{"key":"10.1124\/jpet.123.001664_bib7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.bbr.2016.10.041","article-title":"Post-blast treatment with nociceptin\/orphanin FQ peptide (NOP) receptor antagonist reduces brain injury-induced hypoxia and signaling proteins in vestibulomotor-related brain regions","volume":"340","author":"Awwad","year":"2018","journal-title":"Behav Brain Res"},{"key":"10.1124\/jpet.123.001664_bib8","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3389\/fneur.2015.00132","article-title":"Blast overpressure waves induce transient anxiety and regional changes in cerebral glucose metabolism and delayed hyperarousal in rats","volume":"6","author":"Awwad","year":"2015","journal-title":"Front Neurol"},{"key":"10.1124\/jpet.123.001664_bib9","first-page":"237","article-title":"Vertigo after head injury--a five year follow-up","volume":"7","author":"Berman","year":"1978","journal-title":"J Otolaryngol"},{"key":"10.1124\/jpet.123.001664_bib10","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1177\/1099800419859078","article-title":"Chronic central pain among community-dwelling survivors of moderate-to-severe traumatic brain injury: a quantitative sensory testing study","volume":"21","author":"Boufergu\u00e8ne","year":"2019","journal-title":"Biol Res Nurs"},{"key":"10.1124\/jpet.123.001664_bib11","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1089\/neu.2006.0011","article-title":"Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury","volume":"24","author":"Brody","year":"2007","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib12","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0014-5793(94)00561-3","article-title":"Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type","volume":"347","author":"Bunzow","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1124\/jpet.123.001664_bib13","doi-asserted-by":"crossref","first-page":"454","DOI":"10.3171\/2022.5.JNS22638","article-title":"Serum assessment of traumatic axonal injury: the correlation of GFAP, t-Tau, UCH-L1, and NfL levels with diffusion tensor imaging metrics and its prognosis utility","volume":"138","author":"Casta\u00f1o-Leon","year":"2022","journal-title":"J Neurosurg"},{"key":"10.1124\/jpet.123.001664_bib14","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1161\/hs1101.098367","article-title":"Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats","volume":"32","author":"Chen","year":"2001","journal-title":"Stroke"},{"key":"10.1124\/jpet.123.001664_bib15","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0014-5793(94)00560-5","article-title":"Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family","volume":"347","author":"Chen","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1124\/jpet.123.001664_bib16","doi-asserted-by":"crossref","first-page":"13048","DOI":"10.1523\/JNEUROSCI.4783-06.2006","article-title":"Activation of opioid receptor like-1 receptor in the spinal cord produces sex-specific antinociception in the rat: estrogen attenuates antinociception in the female, whereas testosterone is required for the expression of antinociception in the male","volume":"26","author":"Claiborne","year":"2006","journal-title":"J Neurosci"},{"key":"10.1124\/jpet.123.001664_bib17","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1038\/npp.2011.230","article-title":"The neuropeptide Y (NPY)-ergic system is associated with behavioral resilience to stress exposure in an animal model of post-traumatic stress disorder","volume":"37","author":"Cohen","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1124\/jpet.123.001664_bib18","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1089\/neu.2015.4087","article-title":"Trigeminal pain molecules, allodynia, and photosensitivity are pharmacologically and genetically modulated in a model of traumatic brain injury","volume":"33","author":"Daiutolo","year":"2016","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib19","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1007\/BF02532380","article-title":"Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ","volume":"21","author":"Devine","year":"1996","journal-title":"Neurochem Res"},{"key":"10.1124\/jpet.123.001664_bib20","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1089\/neu.2018.6019","article-title":"Sex differences in acute neuroinflammation after experimental traumatic brain injury are mediated by infiltrating myeloid cells","volume":"36","author":"Doran","year":"2019","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib21","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.jneumeth.2007.10.019","article-title":"An investigation of cerebral edema and injury volume assessments for controlled cortical impact injury","volume":"168","author":"Elliott","year":"2008","journal-title":"J Neurosci Methods"},{"key":"10.1124\/jpet.123.001664_bib22","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/j.1526-4610.2012.02160.x","article-title":"Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury","volume":"52","author":"Elliott","year":"2012","journal-title":"Headache"},{"key":"10.1124\/jpet.123.001664_bib23","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.neubiorev.2004.06.002","article-title":"Motor and cognitive function evaluation following experimental traumatic brain injury","volume":"28","author":"Fujimoto","year":"2004","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1124\/jpet.123.001664_bib24","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/0014-5793(94)80603-9","article-title":"cDNA cloning and regional distribution of a novel member of the opioid receptor family","volume":"343","author":"Fukuda","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1124\/jpet.123.001664_bib25","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.neuroscience.2009.06.021","article-title":"Complete knockout of the nociceptin\/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors","volume":"163","author":"Homberg","year":"2009","journal-title":"Neuroscience"},{"key":"10.1124\/jpet.123.001664_bib26","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1093\/pm\/pnx153","article-title":"Chronic pain after traumatic brain injury: pathophysiology and pain mechanisms","volume":"19","author":"Irvine","year":"2018","journal-title":"Pain Med"},{"key":"10.1124\/jpet.123.001664_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.960741","article-title":"Examining four blood biomarkers for the detection of acute intracranial abnormalities following mild traumatic brain injury in older adults","volume":"13","author":"Iverson","year":"2022","journal-title":"Front Neurol"},{"key":"10.1124\/jpet.123.001664_bib28","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1021\/acs.jmedchem.9b02134","article-title":"Discovery and structure-activity relationships of nociceptin receptor partial agonists that afford symptom ablation in Parkinson\u2019s disease models","volume":"63","author":"Kamakolanu","year":"2020","journal-title":"J Med Chem"},{"key":"10.1124\/jpet.123.001664_bib29","doi-asserted-by":"crossref","first-page":"640","DOI":"10.3389\/fneur.2018.00640","article-title":"Multi-center pre-clinical consortia to enhance translation of therapies and biomarkers for traumatic brain injury: operation brain trauma therapy and beyond","volume":"9","author":"Kochanek","year":"2018","journal-title":"Front Neurol"},{"key":"10.1124\/jpet.123.001664_bib30","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jss.2008.12.022","article-title":"Tau proteins in serum predict outcome after severe traumatic brain injury","volume":"160","author":"Liliang","year":"2010","journal-title":"J Surg Res"},{"key":"10.1124\/jpet.123.001664_bib31","doi-asserted-by":"crossref","first-page":"2430","DOI":"10.1007\/s00415-019-09403-z","article-title":"Vestibular dysfunction in acute traumatic brain injury","volume":"266","author":"Marcus","year":"2019","journal-title":"J Neurol"},{"key":"10.1124\/jpet.123.001664_bib32","doi-asserted-by":"crossref","first-page":"6659","DOI":"10.1523\/JNEUROSCI.0987-04.2004","article-title":"Blockade of nociceptin\/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior","volume":"24","author":"Marti","year":"2004","journal-title":"J Neurosci"},{"key":"10.1124\/jpet.123.001664_bib33","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1016\/j.apmr.2010.05.017","article-title":"Position statement: definition of traumatic brain injury","volume":"91","author":"Menon","year":"2010","journal-title":"Arch Phys Med Rehabil"},{"key":"10.1124\/jpet.123.001664_bib34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0014-5793(94)80235-1","article-title":"ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization","volume":"341","author":"Mollereau","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1124\/jpet.123.001664_bib35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuropharm.2016.03.016","article-title":"Trigeminal neuroplasticity underlies allodynia in a preclinical model of mild closed head traumatic brain injury (cTBI)","volume":"107","author":"Mustafa","year":"2016","journal-title":"Neuropharmacology"},{"year":"2003","series-title":"Report to Congress on Mild Traumatic Brain Injury in the United States: Steps to Prevent a Serious Public Health Problem.","key":"10.1124\/jpet.123.001664_bib36"},{"year":"2014","series-title":"Surveillance Report of Traumatic Brain Injury-Related Emergency Department Visits, Hospitalizations, and Deaths\u2014United States.","key":"10.1124\/jpet.123.001664_bib37"},{"key":"10.1124\/jpet.123.001664_bib38","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1089\/089771503767168465","article-title":"Interaction between anesthesia, gender, and functional outcome task following diffuse traumatic brain injury in rats","volume":"20","author":"O\u2019Connor","year":"2003","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib39","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.pain.2007.06.015","article-title":"The characteristics of chronic central pain after traumatic brain injury","volume":"131","author":"Ofek","year":"2007","journal-title":"Pain"},{"key":"10.1124\/jpet.123.001664_bib40","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1089\/neu.2014.3680","article-title":"Chronic histopathological and behavioral outcomes of experimental traumatic brain injury in adult male animals","volume":"32","author":"Osier","year":"2015","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib41","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3389\/fneur.2016.00134","article-title":"The controlled cortical impact model: applications, considerations for researchers, and future directions","volume":"7","author":"Osier","year":"2016","journal-title":"Front Neurol"},{"key":"10.1124\/jpet.123.001664_bib42","series-title":"Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects","article-title":"Controlled cortical impact model","author":"Osier","year":"2015"},{"key":"10.1124\/jpet.123.001664_bib43","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/S0026-895X(25)08759-0","article-title":"Cloning and functional characterization through antisense mapping of a kappa 3-related opioid receptor","volume":"47","author":"Pan","year":"1995","journal-title":"Mol Pharmacol"},{"key":"10.1124\/jpet.123.001664_bib44","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1080\/02688697.2017.1297378","article-title":"A prospective pilot study on serum cleaved tau protein as a neurological marker in severe traumatic brain injury","volume":"31","author":"Pandey","year":"2017","journal-title":"Br J Neurosurg"},{"key":"10.1124\/jpet.123.001664_bib45","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.1111\/bph.15193","article-title":"The ARRIVE guidelines 2.0: updated guidelines for reporting animal research","volume":"177","author":"Percie du Sert","year":"2020","journal-title":"Br J Pharmacol"},{"key":"10.1124\/jpet.123.001664_bib46","first-page":"1307","article-title":"The pathophysiology of traumatic brain injury at a glance","volume":"6","author":"Prins","year":"2013","journal-title":"Dis Model Mech"},{"key":"10.1124\/jpet.123.001664_bib47","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.neuropharm.2010.12.010","article-title":"Nociceptin\/orphanin FQ receptor knockout rats: in vitro and in vivo studies","volume":"60","author":"Rizzi","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1124\/jpet.123.001664_bib48","article-title":"Multidimensional pain phenotypes after traumatic brain injury","volume":"3","author":"Robayo","year":"2022","journal-title":"Front Pain Res (Lausanne)"},{"key":"10.1124\/jpet.123.001664_bib49","doi-asserted-by":"crossref","DOI":"10.1177\/1179069519844020","article-title":"Sex differences in animal models of traumatic brain injury","volume":"13","author":"Rubin","year":"2019","journal-title":"J Exp Neurosci"},{"key":"10.1124\/jpet.123.001664_bib50","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1016\/j.jpain.2018.06.004","article-title":"Nociceptive and cognitive changes in a murine model of polytrauma","volume":"19","author":"Sahbaie","year":"2018","journal-title":"J Pain"},{"key":"10.1124\/jpet.123.001664_bib51","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1152\/jn.00269.2020","article-title":"Nociceptin\/orphanin FQ peptide receptor mediates inhibition of N-type calcium currents in vestibular afferent neurons of the rat","volume":"124","author":"Sese\u00f1a","year":"2020","journal-title":"J Neurophysiol"},{"key":"10.1124\/jpet.123.001664_bib52","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1089\/neu.2015.4115","article-title":"Nicotinamide treatment in traumatic brain injury: operation brain trauma therapy","volume":"33","author":"Shear","year":"2016","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib53","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.neuroscience.2013.10.034","article-title":"Activation of membrane estrogen receptors attenuates opioid receptor-like1 receptor-mediated antinociception via an ERK-dependent non-genomic mechanism","volume":"255","author":"Small","year":"2013","journal-title":"Neuroscience"},{"key":"10.1124\/jpet.123.001664_bib54","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0006-8993(99)01331-1","article-title":"Modulation of vestibular function by nociceptin\/orphanin FQ: an in vivo and in vitro study","volume":"828","author":"Sulaiman","year":"1999","journal-title":"Brain Res"},{"key":"10.1124\/jpet.123.001664_bib55","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1089\/neu.2015.3977","article-title":"Performance of male and female C57BL\/6J mice on motor and cognitive tasks commonly used in pre-clinical traumatic brain injury research","volume":"33","author":"Tucker","year":"2016","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib56","doi-asserted-by":"crossref","first-page":"14929","DOI":"10.1038\/s41598-020-71879-x","article-title":"Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice","volume":"10","author":"Vogel","year":"2020","journal-title":"Sci Rep"},{"key":"10.1124\/jpet.123.001664_bib57","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0014-5793(94)00557-5","article-title":"cDNA cloning of an orphan opiate receptor gene family member and its splice variant","volume":"348","author":"Wang","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1124\/jpet.123.001664_bib58","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0169-328X(94)90181-3","article-title":"Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors","volume":"27","author":"Wick","year":"1994","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1124\/jpet.123.001664_bib59","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1089\/089771503767168456","article-title":"Traumatic brain injury induces nociceptin\/orphanin FQ expression in neurons of the rat cerebral cortex","volume":"20","author":"Witta","year":"2003","journal-title":"J Neurotrauma"},{"key":"10.1124\/jpet.123.001664_bib60","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/nrn3407","article-title":"Animal models of traumatic brain injury","volume":"14","author":"Xiong","year":"2013","journal-title":"Nat Rev Neurosci"},{"key":"10.1124\/jpet.123.001664_bib61","doi-asserted-by":"crossref","first-page":"731","DOI":"10.3389\/fpsyt.2018.00731","article-title":"Sex differences in nociceptin\/orphanin FQ peptide receptor-mediated pain and anxiety symptoms in a preclinical model of post-traumatic stress disorder","volume":"9","author":"Zhang","year":"2019","journal-title":"Front Psychiatry"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524172382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524172382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/jpet.123.001664","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T17:18:11Z","timestamp":1740763091000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356524172382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S0022356524172382"],"URL":"https:\/\/doi.org\/10.1124\/jpet.123.001664","relation":{},"ISSN":["0022-3565"],"issn-type":[{"type":"print","value":"0022-3565"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recovery from Traumatic Brain Injury Is Nociceptin\/Orphanin FQ Peptide Receptor Genotype-, Sex-, and Injury Severity-Dependent","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/jpet.123.001664","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 by The Author(s)","name":"copyright","label":"Copyright"}]}}