{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T07:47:35Z","timestamp":1778053655325,"version":"3.51.4"},"reference-count":74,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T00:00:00Z","timestamp":1766793600000},"content-version":"am","delay-in-days":360,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R24 DA018055"],"award-info":[{"award-number":["R24 DA018055"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["FBS-43312-26"],"award-info":[{"award-number":["FBS-43312-26"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jpet.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1124\/jpet.124.002240","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T16:28:00Z","timestamp":1719505680000},"page":"100019","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["NOSH-aspirin (NBS-1120) inhibits estrogen receptor\u2013negative breast cancer in\u00a0vitro and in\u00a0vivo by modulating redox-sensitive signaling pathways"],"prefix":"10.1016","volume":"392","author":[{"given":"Mitali","family":"Chattopadhyay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niharika","family":"Nath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravinder","family":"Kodela","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shalaka","family":"Metkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarin A.","family":"Soyemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4060-7283","authenticated-orcid":false,"given":"Khosrow","family":"Kashfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1124\/jpet.124.002240_bib1","doi-asserted-by":"crossref","first-page":"3066","DOI":"10.3390\/ijms25053066","article-title":"Combination treatment with EGFR inhibitor and doxorubicin synergistically inhibits proliferation of MCF-7 cells and MDA-MB-231 triple-negative breast cancer cells in\u00a0vitro","volume":"25","author":"Abrahams","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1124\/jpet.124.002240_bib2","doi-asserted-by":"crossref","first-page":"735","DOI":"10.3390\/biom9110735","article-title":"Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements","volume":"9","author":"Aggarwal","year":"2019","journal-title":"Biomolecules"},{"key":"10.1124\/jpet.124.002240_bib3","doi-asserted-by":"crossref","first-page":"3952","DOI":"10.1038\/sj.onc.1210171","article-title":"Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells","volume":"26","author":"Appierto","year":"2007","journal-title":"Oncogene"},{"key":"10.1124\/jpet.124.002240_bib4","doi-asserted-by":"crossref","first-page":"4295","DOI":"10.1038\/onc.2009.282","article-title":"Pro-proliferative FoxM1 is a target of p53-mediated repression","volume":"28","author":"Barsotti","year":"2009","journal-title":"Oncogene"},{"key":"10.1124\/jpet.124.002240_bib5","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.4049\/jimmunol.130.4.1910","article-title":"Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation","volume":"130","author":"Bass","year":"1983","journal-title":"J\u00a0Immunol"},{"key":"10.1124\/jpet.124.002240_bib6","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1471-2407-8-42","article-title":"Tight correlation between expression of the forkhead transcription factor FOXM1 and HER2 in human breast cancer","volume":"8","author":"Bektas","year":"2008","journal-title":"BMC Cancer"},{"key":"10.1124\/jpet.124.002240_bib7","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1001\/jama.297.18.2018","article-title":"Aspirin dose for the prevention of cardiovascular disease: a systematic review","volume":"297","author":"Campbell","year":"2007","journal-title":"JAMA"},{"key":"10.1124\/jpet.124.002240_bib8","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.bcp.2011.12.019","article-title":"Hydrogen sulfide-releasing aspirin suppresses NF-\u03baB signaling in estrogen receptor negative breast cancer cells in\u00a0vitro and in\u00a0vivo","volume":"83","author":"Chattopadhyay","year":"2012","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2020.113857","article-title":"NOSH-aspirin (NBS-1120) inhibits pancreatic cancer cell growth in a xenograft mouse model: modulation of FoxM1, p53, NF-\u03baB, iNOS, caspase-3 and ROS","volume":"176","author":"Chattopadhyay","year":"2020","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib10","doi-asserted-by":"crossref","first-page":"3338","DOI":"10.3390\/ijms10083338","article-title":"Inhibition of citrinin-induced apoptotic biochemical signaling in human hepatoma G2 cells by resveratrol","volume":"10","author":"Chen","year":"2009","journal-title":"Int J Mol Sci"},{"key":"10.1124\/jpet.124.002240_bib11","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1002\/ijc.24209","article-title":"Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2\/M arrest in A549 lung cancer cells","volume":"124","author":"Chetty","year":"2009","journal-title":"Int J Cancer"},{"key":"10.1124\/jpet.124.002240_bib12","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.3181\/0903-RM-98","article-title":"Cell cycle arrest induced by hydrogen peroxide is associated with modulation of oxidative stress related genes in breast cancer cells","volume":"234","author":"Chua","year":"2009","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1124\/jpet.124.002240_bib13","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.niox.2014.12.009","article-title":"On the chemical biology of the nitrite\/sulfide interaction","volume":"46","author":"Cortese-Krott","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1124\/jpet.124.002240_bib14","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S1470-2045(09)70035-X","article-title":"Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement","volume":"10","author":"Cuzick","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1124\/jpet.124.002240_bib15","first-page":"1571","article-title":"Relationship between p21 expression and mutation of the p53 tumor suppressor gene in normal and malignant ovarian epithelial cells","volume":"2","author":"Elbendary","year":"1996","journal-title":"Clin Cancer Res"},{"key":"10.1124\/jpet.124.002240_bib16","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/0092-8674(93)90500-P","article-title":"WAF1, a potential mediator of p53 tumor suppression","volume":"75","author":"el-Deiry","year":"1993","journal-title":"Cell"},{"key":"10.1124\/jpet.124.002240_bib17","doi-asserted-by":"crossref","first-page":"12016","DOI":"10.1021\/ja3009693","article-title":"Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols","volume":"134","author":"Filipovic","year":"2012","journal-title":"J\u00a0Am Chem Soc"},{"key":"10.1124\/jpet.124.002240_bib18","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1016\/0959-8049(94)00293-E","article-title":"Oestradiol stimulates growth of oestrogen receptor-negative MDA-MB-231 breast cancer cells in immunodeficient mice by reducing cell loss","volume":"30a","author":"Friedl","year":"1994","journal-title":"Eur J Cancer"},{"key":"10.1124\/jpet.124.002240_bib19","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.freeradbiomed.2017.01.004","article-title":"Reactive oxygen species and cancer paradox: to promote or to suppress?","volume":"104","author":"Galadari","year":"2017","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/jpet.124.002240_bib20","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1517\/14728222.12.6.663","article-title":"FoxM1 inhibitors as potential anticancer drugs","volume":"12","author":"Gartel","year":"2008","journal-title":"Expert Opin Ther Targets"},{"key":"10.1124\/jpet.124.002240_bib21","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3322\/caac.21718","article-title":"Cancer statistics for African American\/Black People 2022","volume":"72","author":"Giaquinto","year":"2022","journal-title":"CA Cancer J Clin"},{"key":"10.1124\/jpet.124.002240_bib22","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ajpath.2013.03.012","article-title":"Combination of oxidative stress and FOXM1 inhibitors induces apoptosis in cancer cells and inhibits xenograft tumor growth","volume":"183","author":"Halasi","year":"2013","journal-title":"Am J Pathol"},{"key":"10.1124\/jpet.124.002240_bib23","doi-asserted-by":"crossref","first-page":"16619","DOI":"10.18632\/oncotarget.7672","article-title":"FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorigenesis of human triple negative breast cancer cells","volume":"7","author":"Hamurcu","year":"2016","journal-title":"Oncotarget"},{"key":"10.1124\/jpet.124.002240_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0279784","article-title":"Oral aspirin for preventing colorectal adenoma recurrence: a systematic review and network meta-analysis of randomized controlled trials","volume":"19","author":"Hoang","year":"2024","journal-title":"PLoS One"},{"key":"10.1124\/jpet.124.002240_bib25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1054-3589(08)57002-5","article-title":"Anti-inflammatory agents as cancer therapeutics","volume":"57","author":"Kashfi","year":"2009","journal-title":"Adv Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib26","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.bcp.2018.01.042","article-title":"The dichotomous role of H(2)S in cancer cell biology? D\u00e9j\u00e0 vu all over again","volume":"149","author":"Kashfi","year":"2018","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib27","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.bcp.2012.10.019","article-title":"Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras","volume":"85","author":"Kashfi","year":"2013","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib28","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1021\/ml300002m","article-title":"NOSH-aspirin: a novel nitric oxide-hydrogen sulfide-releasing hybrid: a new class of anti-inflammatory pharmaceuticals","volume":"3","author":"Kodela","year":"2012","journal-title":"ACS Med Chem Lett"},{"key":"10.1124\/jpet.124.002240_bib29","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/j.bcp.2015.09.014","article-title":"NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications","volume":"98","author":"Kodela","year":"2015","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib30","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1054\/mehy.1999.0982","article-title":"A\u00a0threshold concept for cancer therapy","volume":"55","author":"Kong","year":"2000","journal-title":"Med Hypotheses"},{"key":"10.1124\/jpet.124.002240_bib31","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.bbagrm.2011.09.004","article-title":"FOXM1: From cancer initiation to progression and treatment","volume":"1819","author":"Koo","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/jpet.124.002240_bib32","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1080\/1061186X.2023.2245579","article-title":"Emerging targeted therapeutic strategies for the treatment of triple-negative breast cancer","volume":"31","author":"Kumari","year":"2023","journal-title":"J\u00a0Drug Target"},{"key":"10.1124\/jpet.124.002240_bib33","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1158\/1541-7786.MCR-09-0432","article-title":"FOXM1 confers acquired cisplatin resistance in breast cancer cells","volume":"8","author":"Kwok","year":"2010","journal-title":"Mol Cancer Res"},{"key":"10.1124\/jpet.124.002240_bib34","first-page":"92","article-title":"FoxM1: at the crossroads of ageing and cancer","volume":"1775","author":"Laoukili","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/jpet.124.002240_bib35","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1021\/tx00026a012","article-title":"Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress","volume":"5","author":"LeBel","year":"1992","journal-title":"Chem Res Toxicol"},{"key":"10.1124\/jpet.124.002240_bib36","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.freeradbiomed.2008.01.011","article-title":"ROS and p53: a versatile partnership","volume":"44","author":"Liu","year":"2008","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/jpet.124.002240_bib37","doi-asserted-by":"crossref","first-page":"466","DOI":"10.3322\/caac.21695","article-title":"Cancer statistics for the US Hispanic\/Latino population, 2021","volume":"71","author":"Miller","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"10.1124\/jpet.124.002240_bib38","first-page":"1857","article-title":"Apoptosis induced by 7-difluoromethoxyl-5,4'-di-n-octyl genistein via the inactivation of FoxM1 in ovarian cancer cells","volume":"27","author":"Ning","year":"2012","journal-title":"Oncol Rep"},{"key":"10.1124\/jpet.124.002240_bib39","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1158\/0008-5472.CAN-05-3118","article-title":"Nitric oxide-donating aspirin prevents pancreatic cancer in a hamster tumor model","volume":"66","author":"Ouyang","year":"2006","journal-title":"Cancer Res"},{"key":"10.1124\/jpet.124.002240_bib40","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.niox.2022.08.003","article-title":"Utility of NO and H(2)S donating platforms in managing COVID-19: rationale and promise","volume":"128","author":"Oza","year":"2022","journal-title":"Nitric Oxide"},{"key":"10.1124\/jpet.124.002240_bib41","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.4161\/cc.8.20.9628","article-title":"p53 negatively regulates expression of FoxM1","volume":"8","author":"Pandit","year":"2009","journal-title":"Cell Cycle"},{"key":"10.1124\/jpet.124.002240_bib42","doi-asserted-by":"crossref","first-page":"2908","DOI":"10.1038\/emboj.2009.239","article-title":"FoxM1, a critical regulator of oxidative stress during oncogenesis","volume":"28","author":"Park","year":"2009","journal-title":"EMBO J"},{"key":"10.1124\/jpet.124.002240_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1362217","article-title":"Optimizing aspirin dose for colorectal cancer patients through deep phenotyping using novel biomarkers of drug action","volume":"15","author":"Patrignani","year":"2024","journal-title":"Front Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib44","doi-asserted-by":"crossref","first-page":"37832","DOI":"10.1074\/jbc.M301546200","article-title":"Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism","volume":"278","author":"Pelicano","year":"2003","journal-title":"J\u00a0Biol Chem"},{"key":"10.1124\/jpet.124.002240_bib45","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/35021093","article-title":"Molecular portraits of human breast tumours","volume":"406","author":"Perou","year":"2000","journal-title":"Nature"},{"key":"10.1124\/jpet.124.002240_bib46","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1074\/jbc.M705792200","article-title":"FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression","volume":"283","author":"Petrovic","year":"2008","journal-title":"J\u00a0Biol Chem"},{"key":"10.1124\/jpet.124.002240_bib47","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1593\/neo.04277","article-title":"Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data","volume":"6","author":"Pilarsky","year":"2004","journal-title":"Neoplasia"},{"key":"10.1124\/jpet.124.002240_bib48","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00001813-200007000-00002","article-title":"Does p53 status influence tumor response to anticancer therapies?","volume":"11","author":"Pirollo","year":"2000","journal-title":"Anticancer Drugs"},{"key":"10.1124\/jpet.124.002240_bib49","doi-asserted-by":"crossref","first-page":"c1","DOI":"10.1038\/nrc2223-c1","article-title":"FOXM1: the Achilles\u2019 heel of cancer?","volume":"8","author":"Radhakrishnan","year":"2008","journal-title":"Nat Rev Cancer"},{"key":"10.1124\/jpet.124.002240_bib50","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1146\/annurev-cancerbio-041916-065808","article-title":"The two faces of reactive oxygen species in cancer","volume":"1","author":"Reczek","year":"2017","journal-title":"Annu Rev Cancer Biol"},{"key":"10.1124\/jpet.124.002240_bib51","doi-asserted-by":"crossref","first-page":"15038","DOI":"10.1073\/pnas.0601945103","article-title":"Selective fluorescent imaging of superoxide in\u00a0vivo using ethidium-based probes","volume":"103","author":"Robinson","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1124\/jpet.124.002240_bib52","first-page":"202","article-title":"Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents","volume":"8","author":"Rodr\u00edguez-Burford","year":"2002","journal-title":"Clin Cancer Res"},{"key":"10.1124\/jpet.124.002240_bib53","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/S0140-6736(11)61720-0","article-title":"Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials","volume":"379","author":"Rothwell","year":"2012","journal-title":"Lancet"},{"key":"10.1124\/jpet.124.002240_bib54","first-page":"527","article-title":"Cyclooxygenase inhibitors decrease the growth and induce regression of human esophageal adenocarcinoma xenografts in nude mice","volume":"40","author":"Santander","year":"2012","journal-title":"Int J Oncol"},{"key":"10.1124\/jpet.124.002240_bib55","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3389\/fonc.2019.00480","article-title":"Breast cancer subtypes present a differential production of reactive oxygen species (ROS) and susceptibility to antioxidant treatment","volume":"9","author":"Sarmiento-Salinas","year":"2019","journal-title":"Front Oncol"},{"key":"10.1124\/jpet.124.002240_bib56","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.18632\/aging.100988","article-title":"FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells","volume":"8","author":"Smirnov","year":"2016","journal-title":"Aging (Albany NY)"},{"key":"10.1124\/jpet.124.002240_bib57","doi-asserted-by":"crossref","first-page":"10869","DOI":"10.1073\/pnas.191367098","article-title":"Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications","volume":"98","author":"S\u00f8rlie","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1124\/jpet.124.002240_bib58","doi-asserted-by":"crossref","first-page":"10393","DOI":"10.1073\/pnas.1732912100","article-title":"Breast cancer classification and prognosis based on gene expression profiles from a population-based study","volume":"100","author":"Sotiriou","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1124\/jpet.124.002240_bib59","first-page":"35","article-title":"The expression patterns of ER, PR, HER2, CK5\/6, EGFR, Ki-67 and AR by immunohistochemical analysis in breast cancer cell lines","volume":"4","author":"Subik","year":"2010","journal-title":"Breast Cancer (Auckl)"},{"key":"10.1124\/jpet.124.002240_bib60","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/2049-3002-2-17","article-title":"Mitochondrial reactive oxygen species and cancer","volume":"2","author":"Sullivan","year":"2014","journal-title":"Cancer Metab"},{"key":"10.1124\/jpet.124.002240_bib61","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1126\/science.270.5234.296","article-title":"Requirement for generation of H2O2 for platelet-derived growth factor signal transduction","volume":"270","author":"Sundaresan","year":"1995","journal-title":"Science"},{"key":"10.1124\/jpet.124.002240_bib62","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1128\/MCB.01068-06","article-title":"Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes","volume":"27","author":"Tan","year":"2007","journal-title":"Mol Cell Biol"},{"key":"10.1124\/jpet.124.002240_bib63","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ccr.2006.08.009","article-title":"Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate","volume":"10","author":"Trachootham","year":"2006","journal-title":"Cancer Cell"},{"key":"10.1124\/jpet.124.002240_bib64","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/sj.bjp.0707396","article-title":"Building a better aspirin: gaseous solutions to a century-old problem","volume":"152","author":"Wallace","year":"2007","journal-title":"Br J Pharmacol"},{"key":"10.1124\/jpet.124.002240_bib65","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ctrv.2009.11.006","article-title":"Forkhead box M1 transcription factor: a novel target for cancer therapy","volume":"36","author":"Wang","year":"2010","journal-title":"Cancer Treat Rev"},{"key":"10.1124\/jpet.124.002240_bib66","doi-asserted-by":"crossref","first-page":"10875","DOI":"10.1128\/MCB.25.24.10875-10894.2005","article-title":"Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase","volume":"25","author":"Wang","year":"2005","journal-title":"Mol Cell Biol"},{"key":"10.1124\/jpet.124.002240_bib67","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.18632\/oncotarget.359","article-title":"The suppression of FOXM1 and its targets in breast cancer xenograft tumors by siRNA","volume":"2","author":"Wang","year":"2011","journal-title":"Oncotarget"},{"key":"10.1124\/jpet.124.002240_bib68","doi-asserted-by":"crossref","first-page":"4839","DOI":"10.7150\/thno.56747","article-title":"The double-edged roles of ROS in cancer prevention and therapy","volume":"11","author":"Wang","year":"2021","journal-title":"Theranostics"},{"key":"10.1124\/jpet.124.002240_bib69","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1479-5876-8-37","article-title":"Oxidative stress in NSC-741909-induced apoptosis of cancer cells","volume":"8","author":"Wei","year":"2010","journal-title":"J\u00a0Transl Med"},{"key":"10.1124\/jpet.124.002240_bib70","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1038\/sj.bjc.6604392","article-title":"Inverse association of NSAID use and ovarian cancer in relation to oral contraceptive use and parity","volume":"98","author":"Wernli","year":"2008","journal-title":"Br J Cancer"},{"key":"10.1124\/jpet.124.002240_bib71","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1515\/BC.2007.159","article-title":"FOXM1, a typical proliferation-associated transcription factor","volume":"388","author":"Wierstra","year":"2007","journal-title":"Biol Chem"},{"key":"10.1124\/jpet.124.002240_bib72","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1056\/NEJM199906173402407","article-title":"Gastrointestinal toxicity of nonsteroidal anti-inflammatory drugs","volume":"340","author":"Wolfe","year":"1999","journal-title":"N\u00a0Engl J Med"},{"key":"10.1124\/jpet.124.002240_bib73","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2741\/s5","article-title":"Imaging reactive oxygen species dynamics in living cells and tissues","volume":"1","author":"Wu","year":"2009","journal-title":"Front Biosci (Schol Ed)"},{"key":"10.1124\/jpet.124.002240_bib74","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF01806216","article-title":"Simultaneous expression of nitric oxide synthase and estrogen receptor in human breast cancer cell lines","volume":"40","author":"Zeillinger","year":"1996","journal-title":"Breast Cancer Res Treat"}],"container-title":["The Journal of Pharmacology and Experimental Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524000776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022356524000776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/jpet.124.002240","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T23:10:50Z","timestamp":1738278650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022356524000776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":74,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["S0022356524000776"],"URL":"https:\/\/doi.org\/10.1124\/jpet.124.002240","relation":{},"ISSN":["0022-3565"],"issn-type":[{"value":"0022-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NOSH-aspirin (NBS-1120) inhibits estrogen receptor\u2013negative breast cancer in\u00a0vitro and in\u00a0vivo by modulating redox-sensitive signaling pathways","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pharmacology and Experimental Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/jpet.124.002240","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Society for Pharmacology and Experimental Therapeutics. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"100019"}}