{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T06:32:27Z","timestamp":1768458747664,"version":"3.49.0"},"reference-count":72,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["molpharm.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Pharmacology"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1124\/mol.105.013086","type":"journal-article","created":{"date-parts":[[2005,7,19]],"date-time":"2005-07-19T00:33:26Z","timestamp":1121733206000},"page":"1006-1017","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Nitric Oxide Donors Induce Neurotrophin-Like Survival Signaling and Protect Neurons against Apoptosis"],"prefix":"10.1016","volume":"68","author":[{"given":"Carsten","family":"Culmsee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Gerling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Landshamer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca","family":"Rickerts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-J\u00fcrgen","family":"Duchstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Umezawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanne","family":"Klumpp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josef","family":"Krieglstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1124\/mol.105.013086_bib1","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S0166-2236(02)02254-3","article-title":"cGMP and S-nitrosylation: two routes for modulation of neuronal excitability by NO","volume":"25","author":"Ahern","year":"2002","journal-title":"Trends Neurosci"},{"key":"10.1124\/mol.105.013086_bib2","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1042\/bj3570593","article-title":"Nitric oxide synthases: structure, function and inhibition","volume":"357","author":"Alderton","year":"2001","journal-title":"Biochem J"},{"key":"10.1124\/mol.105.013086_bib3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0959-4388(00)00211-7","article-title":"Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway","volume":"11","author":"Brunet","year":"2001","journal-title":"Curr Opin Neurobiol"},{"key":"10.1124\/mol.105.013086_bib4","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1128\/MCB.22.7.1998-2010.2002","article-title":"Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblasts","volume":"22","author":"Buckley","year":"2002","journal-title":"Mol Cell Biol"},{"key":"10.1124\/mol.105.013086_bib5","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/S0891-5849(99)00015-5","article-title":"Nitric oxide and superoxide inhibit platelet-derived growth factor receptor phosphotyrosine phosphatases","volume":"26","author":"Callsen","year":"1999","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/mol.105.013086_bib6","doi-asserted-by":"crossref","first-page":"24878","DOI":"10.1016\/S0021-9258(17)31472-2","article-title":"Nitric oxide causes inactivation of the low molecular weight phosphotyrosine protein phosphatase","volume":"269","author":"Caselli","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib7","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0014-5793(95)01120-4","article-title":"In vivo inactivation of phosphotyrosine protein phosphatases by nitric oxide","volume":"374","author":"Caselli","year":"1995","journal-title":"FEBS Lett"},{"key":"10.1124\/mol.105.013086_bib8","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0012-1606(03)00120-9","article-title":"Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain","volume":"258","author":"Cheng","year":"2003","journal-title":"Dev Biol"},{"key":"10.1124\/mol.105.013086_bib9","doi-asserted-by":"crossref","first-page":"49896","DOI":"10.1074\/jbc.M206177200","article-title":"Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation","volume":"277","author":"Ciani","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib10","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.neuint.2004.03.021","article-title":"Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation","volume":"45","author":"Contestabile","year":"2004","journal-title":"Neurochem Int"},{"key":"10.1124\/mol.105.013086_bib11","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1523\/JNEUROSCI.18-08-02933.1998","article-title":"Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons","volume":"18","author":"Crowder","year":"1998","journal-title":"J Neurosci"},{"key":"10.1124\/mol.105.013086_bib12","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/S0306-4522(02)00539-0","article-title":"Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor p75","volume":"115","author":"Culmsee","year":"2002","journal-title":"Neurosci"},{"key":"10.1124\/mol.105.013086_bib13","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1146\/annurev.pharmtox.41.1.203","article-title":"Novel effects of nitric oxide","volume":"41","author":"Davis","year":"2001","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1124\/mol.105.013086_bib14","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/ana.410320302","article-title":"A novel neuronal messenger molecule in brain: the free radical, nitric oxide","volume":"32","author":"Dawson","year":"1992","journal-title":"Ann Neurol"},{"key":"10.1124\/mol.105.013086_bib15","doi-asserted-by":"crossref","first-page":"5910","DOI":"10.1523\/JNEUROSCI.19-14-05910.1999","article-title":"Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage","volume":"19","author":"Eliasson","year":"1999","journal-title":"J Neurosci"},{"key":"10.1124\/mol.105.013086_bib16","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1073\/pnas.95.15.8880","article-title":"Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase","volume":"95","author":"Endres","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/mol.105.013086_bib17","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1523\/JNEUROSCI.16-07-02325.1996","article-title":"Nitric oxide delays the death of trophic factor-deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism","volume":"16","author":"Farinelli","year":"1996","journal-title":"J Neurosci"},{"key":"10.1124\/mol.105.013086_bib18","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1097\/00001756-199707280-00011","article-title":"Orthovanadate induces cell death in rat dentate gyrus primary culture","volume":"8","author":"Figiel","year":"1997","journal-title":"Neuroreport"},{"key":"10.1124\/mol.105.013086_bib19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.brainres.2004.11.024","article-title":"SNAP, a NO donor, induces cellular protection only when cortical neurons are submitted to some aggression process","volume":"1034","author":"Figueroa","year":"2005","journal-title":"Brain Res"},{"key":"10.1124\/mol.105.013086_bib20","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1006\/bbrc.1997.7174","article-title":"Enhancement or induction of neurite formation by a protein tyrosine phosphates inhibitor, 3,4-dephostatin, in growth factor treated PC12h cells","volume":"238","author":"Fujiwara","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/mol.105.013086_bib21","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/288373a0","article-title":"The obligatory role of endothelial cells in the relaxation of arterial smooth muscle cells by acetylcholine","volume":"288","author":"Furchgott","year":"1980","journal-title":"Nature (Lond)"},{"key":"10.1124\/mol.105.013086_bib22","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1146\/annurev.ph.57.030195.003343","article-title":"Nitric oxide signaling in the central nervous system","volume":"57","author":"Garthwaite","year":"1995","journal-title":"Annu Rev Physiol"},{"key":"10.1124\/mol.105.013086_bib23","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.neuint.2003.08.013","article-title":"The tyrosine phosphatase inhibitor orthovanadate mimics NGF-induced neuroprotective signaling in rat hippocampal neurons","volume":"44","author":"Gerling","year":"2004","journal-title":"Neurochem Int"},{"key":"10.1124\/mol.105.013086_bib24","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/00004647-199903000-00011","article-title":"Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning","volume":"19","author":"Gidday","year":"1999","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1124\/mol.105.013086_bib25","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/353170a0","article-title":"Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases","volume":"353","author":"G\u00f3mez","year":"1991","journal-title":"Nature (Lond)"},{"key":"10.1124\/mol.105.013086_bib26","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1073\/pnas.97.1.436","article-title":"Requirement for nitric oxide activation of p21(ras)\/extracellular regulated kinase in neuronal ischemic preconditioning","volume":"97","author":"Gonzalez-Zulueta","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/mol.105.013086_bib27","first-page":"211","article-title":"Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamine","volume":"5","author":"Gruetter","year":"1979","journal-title":"J Cyclic Nucleotide Res"},{"key":"10.1124\/mol.105.013086_bib28","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1096\/fj.02-0738com","article-title":"Nitric oxide prevents 6-hydroxydopamine-induced apoptosis in PC12 cells through cGMP-dependent PI3-kinase\/Akt activation","volume":"17","author":"Ha","year":"2003","journal-title":"FASEB J"},{"key":"10.1124\/mol.105.013086_bib29","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1006\/niox.1997.0134","article-title":"Effects of redox-related congeners of NO on apoptosis and caspase-3 activity","volume":"1","author":"Haendeler","year":"1997","journal-title":"Nitric Oxide"},{"key":"10.1124\/mol.105.013086_bib30","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1074\/jbc.M210194200","article-title":"Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B","volume":"278","author":"Haj","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib31","first-page":"801","article-title":"NO, nitrotyrosine and cyclic GMP in signal transduction","volume":"7","author":"Hanafy","year":"2001","journal-title":"Med Sci Monit"},{"key":"10.1124\/mol.105.013086_bib32","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/(SICI)1097-4547(19970215)47:4<427::AID-JNR8>3.0.CO;2-G","article-title":"Nitric oxide donors enhance neurotrophin-induced neurite outgrowth through a cGMP-dependent mechanism","volume":"47","author":"Hindley","year":"1997","journal-title":"J Neurosci Res"},{"key":"10.1124\/mol.105.013086_bib33","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0753-3322(02)00176-2","article-title":"Antidiabetic effect of a nitrosamine-free dephostatin analogue, methoxime-3,4-dephostatin, in db\/db mice","volume":"56","author":"Hiroki","year":"2002","journal-title":"Biomed Pharmacother"},{"key":"10.1124\/mol.105.013086_bib34","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1006\/nbdi.1994.0007","article-title":"NOS induction by NGF in basal forebrain cholinergic neurones: evidence for regulation of brain NOS by a neurotrophin","volume":"1","author":"Holtzman","year":"1994","journal-title":"Neurobiol Dis"},{"key":"10.1124\/mol.105.013086_bib35","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1097\/00004647-199609000-00023","article-title":"Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-l-arginine","volume":"16","author":"Huang","year":"1996","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1124\/mol.105.013086_bib36","first-page":"286","article-title":"Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage","volume":"268","author":"Iadecola","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1124\/mol.105.013086_bib37","doi-asserted-by":"crossref","first-page":"19810","DOI":"10.1074\/jbc.271.33.19810","article-title":"Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling","volume":"271","author":"Kenner","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib38","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0304-3940(03)00451-8","article-title":"Nitric oxide mediates membrane depolarization-promoted survival of rat neuronal PC12 cells","volume":"344","author":"Kim","year":"2003","journal-title":"Neurosci Lett"},{"key":"10.1124\/mol.105.013086_bib39","doi-asserted-by":"crossref","first-page":"6740","DOI":"10.1523\/JNEUROSCI.19-16-06740.1999","article-title":"Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling","volume":"19","author":"Kim","year":"1999","journal-title":"J Neurosci"},{"key":"10.1124\/mol.105.013086_bib40","doi-asserted-by":"crossref","first-page":"31437","DOI":"10.1074\/jbc.273.47.31437","article-title":"Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release","volume":"273","author":"Kim","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib41","doi-asserted-by":"crossref","first-page":"31138","DOI":"10.1074\/jbc.272.49.31138","article-title":"Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms","volume":"272","author":"Kim","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib42","doi-asserted-by":"crossref","first-page":"2442","DOI":"10.1161\/01.STR.31.10.2442","article-title":"Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation and protects from cerebral ischemia in normocholesterolemic mice","volume":"31","author":"Laufs","year":"2000","journal-title":"Stroke"},{"key":"10.1124\/mol.105.013086_bib43","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1097\/00005072-199911000-00006","article-title":"Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles and senile plaques","volume":"58","author":"Lee","year":"1999","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1124\/mol.105.013086_bib44","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1006\/bbrc.1997.7672","article-title":"Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation","volume":"240","author":"Li","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/mol.105.013086_bib45","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1038\/70978","article-title":"Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease","volume":"5","author":"Liberatore","year":"1999","journal-title":"Nat Med"},{"key":"10.1124\/mol.105.013086_bib46","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1038\/sj.cdd.4400580","article-title":"Neuronal protection and destruction by NO","volume":"6","author":"Lipton","year":"1999","journal-title":"Cell Death Differ"},{"key":"10.1124\/mol.105.013086_bib47","first-page":"483","article-title":"Iodosobenzene","volume":"3","author":"Lucas","year":"1995","journal-title":"Org Synth Coll"},{"key":"10.1124\/mol.105.013086_bib48","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1006\/exnr.2002.8042","article-title":"Tyrosine phosphatase inhibition enhances neurotrophin potency and rescues nigrostriatal neurons in adult rats","volume":"178","author":"Lu","year":"2002","journal-title":"Exp Neurol"},{"key":"10.1124\/mol.105.013086_bib49","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1021\/bi0265574","article-title":"Identification of protein tyrosine phosphatases associating with the PDGF receptor","volume":"42","author":"Markova","year":"2003","journal-title":"Biochemistry"},{"key":"10.1124\/mol.105.013086_bib50","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1083\/jcb.200309036","article-title":"SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase","volume":"163","author":"Marsh","year":"2003","journal-title":"J Cell Biol"},{"key":"10.1124\/mol.105.013086_bib51","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0891-5849(99)00233-6","article-title":"Nitric oxide stimulates tyrosine phosphorylation of focal adhesion kinase, Src kinase and mitogen-activated protein kinases in murine fibroblasts","volume":"28","author":"Monteiro","year":"2000","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/mol.105.013086_bib52","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/S0165-6147(98)01257-7","article-title":"From Vanadis to Atropos: vanadium compounds as pharmacological tools in cell death signalling","volume":"19","author":"Morinville","year":"1998","journal-title":"Trends Pharmacol Sci"},{"key":"10.1124\/mol.105.013086_bib53","doi-asserted-by":"crossref","first-page":"8841","DOI":"10.1073\/pnas.97.16.8841","article-title":"Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens","volume":"97","author":"Nathan","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/mol.105.013086_bib54","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0891-5849(03)00311-3","article-title":"Nitric oxide and cGMP activate the RAS-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells","volume":"35","author":"Oliveira","year":"2003","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/mol.105.013086_bib55","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1083\/jcb.139.3.809","article-title":"Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons","volume":"139","author":"Philpott","year":"1997","journal-title":"J Cell Biol"},{"key":"10.1124\/mol.105.013086_bib56","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/07853890310004093","article-title":"Signaling through NO and cGMP-dependent protein kinases","volume":"35","author":"Schlossmann","year":"2003","journal-title":"Ann Med"},{"key":"10.1124\/mol.105.013086_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0026-895X(25)09113-8","article-title":"Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase","volume":"50","author":"Schrammel","year":"1996","journal-title":"Mol Pharmacol"},{"key":"10.1124\/mol.105.013086_bib58","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0014-5793(98)00844-8","article-title":"Nitirc oxide induces and inhibits apoptosis through different pathways","volume":"433","author":"Shen","year":"1998","journal-title":"FEBS Lett"},{"key":"10.1124\/mol.105.013086_bib59","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1146\/annurev.neuro.24.1.1217","article-title":"Nerve growth factor signaling, neuroprotection and neural repair","volume":"24","author":"Sofroniew","year":"2001","journal-title":"Annu Rev Neurosci"},{"key":"10.1124\/mol.105.013086_bib60","doi-asserted-by":"crossref","first-page":"27511","DOI":"10.1074\/jbc.M011726200","article-title":"Potentiation of insulin-related signal transduction by a novel protein-tyrosine-phosphatase inhibitor, Et-3,4 dephostatin, on cultured 3T3\u2013L1 adipocytes","volume":"276","author":"Suzuki","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1124\/mol.105.013086_bib61","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0006-8993(97)81694-0","article-title":"Cyclic guanosine 3\u2032,5\u2032-monophosphate-mediated neuroprotection by nitric oxide in dissociated cultures of rat dorsal root ganglion neurones","volume":"774","author":"Thippeswamy","year":"1997","journal-title":"Brain Res"},{"key":"10.1124\/mol.105.013086_bib62","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1523\/JNEUROSCI.20-04-01386.2000","article-title":"Caspase-2 mediates neuronal cell death induced by beta-amyloid","volume":"20","author":"Troy","year":"2000","journal-title":"J Neurosci"},{"key":"10.1124\/mol.105.013086_bib63","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0163-7258(03)00050-0","article-title":"Molecular design and biological activities of protein-tyrosine phosphatase inhibitors","volume":"99","author":"Umezawa","year":"2003","journal-title":"Pharmacol Ther"},{"key":"10.1124\/mol.105.013086_bib64","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1080\/146608201316949415","article-title":"The role of nitric oxide in amyotrophic lateral sclerosis","volume":"2","author":"Urushitani","year":"2001","journal-title":"Amyotroph Lateral Scler Other Motor Neuron Disord"},{"key":"10.1124\/mol.105.013086_bib65","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1046\/j.1471-4159.1999.0721843.x","article-title":"Analysis of the neuroprotective effects of various nitric oxide donor compounds in murine mixed cortical cell culture","volume":"72","author":"Vidwans","year":"1999","journal-title":"J Neurochem"},{"key":"10.1124\/mol.105.013086_bib66","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0301-0082(94)90023-X","article-title":"Nitric oxide: a radical neurotransmitter in the central nervous system","volume":"42","author":"Vincent","year":"1994","journal-title":"Prog Neurobiol"},{"key":"10.1124\/mol.105.013086_bib67","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1073\/pnas.91.6.2151","article-title":"Existence of nitric oxide synthase in rat hippocampal pyramidal cells","volume":"91","author":"Wendland","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/mol.105.013086_bib68","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1126\/science.270.5240.1326","article-title":"Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis","volume":"270","author":"Xia","year":"1995","journal-title":"Science (Wash DC)"},{"key":"10.1124\/mol.105.013086_bib69","doi-asserted-by":"crossref","first-page":"5773","DOI":"10.1073\/pnas.95.10.5773","article-title":"Nitric oxide mediates N-methyl-d-aspartate receptor-induced activation of p21ras","volume":"95","author":"Yun","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/mol.105.013086_bib70","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1161\/01.STR.27.2.317","article-title":"Aminoguanidine ameliorates and l-arginine worsens brain damage from intraluminal middle cerebral artery occlusion","volume":"27","author":"Zhang","year":"1996","journal-title":"Stroke"},{"key":"10.1124\/mol.105.013086_bib71","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0163-7258(02)00199-7","article-title":"Modulation of protein kinase signaling by protein phosphatases and inhibitors","volume":"93","author":"Zhang","year":"2002","journal-title":"Pharmacol Ther"},{"key":"10.1124\/mol.105.013086_bib72","doi-asserted-by":"crossref","first-page":"3898","DOI":"10.1523\/JNEUROSCI.22-10-03898.2002","article-title":"Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage","volume":"22","author":"Zhu","year":"2002","journal-title":"J Neurosci"}],"container-title":["Molecular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026895X24064976?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0026895X24064976?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/mol.105.013086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T08:59:00Z","timestamp":1740041940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0026895X24064976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":72,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0026895X24064976"],"URL":"https:\/\/doi.org\/10.1124\/mol.105.013086","relation":{},"ISSN":["0026-895X"],"issn-type":[{"value":"0026-895X","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nitric Oxide Donors Induce Neurotrophin-Like Survival Signaling and Protect Neurons against Apoptosis","name":"articletitle","label":"Article Title"},{"value":"Molecular Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/mol.105.013086","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2005 The American Society for Pharmacology and Experimental Therapeutics","name":"copyright","label":"Copyright"}]}}