{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:25:51Z","timestamp":1777364751781,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mol Pharmacol"],"published-print":{"date-parts":[[2001,5,1]]},"DOI":"10.1124\/mol.59.5.1333","type":"journal-article","created":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T20:42:33Z","timestamp":1515444153000},"page":"1333-1342","source":"Crossref","is-referenced-by-count":89,"title":["Rhodostomin, A Snake Venom Disintegrin, Inhibits Angiogenesis Elicited by Basic Fibroblast Growth Factor and Suppresses Tumor Growth by A Selective \u03b1<sub>v<\/sub>\u03b2<sub>3<\/sub>Blockade of Endothelial Cells"],"prefix":"10.1016","volume":"59","author":[{"given":"Chia-Hsin","family":"Yeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Chin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong-Seng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tur-Fu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","published-online":{"date-parts":[[2001,5,1]]},"reference":[{"key":"2019092417243519000_59.5.1333.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(99)00279-8"},{"key":"2019092417243519000_59.5.1333.2","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1999.4559"},{"key":"2019092417243519000_59.5.1333.3","doi-asserted-by":"publisher","DOI":"10.1126\/science.7512751"},{"key":"2019092417243519000_59.5.1333.4","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90007-8"},{"key":"2019092417243519000_59.5.1333.5","doi-asserted-by":"crossref","unstructured":"Byzova TV Plow EF (1998) Activation of \u03b1v\u03b23 on vascular cells controls recognition of prothrombin J Cell Biol 143:2081\u20132092.","DOI":"10.1083\/jcb.143.7.2081"},{"key":"2019092417243519000_59.5.1333.6","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1055\/s-0037-1615250","article-title":"Role of integrin \u03b1v\u03b23 in vascular biology.","volume":"80","author":"Byzova","year":"1998","journal-title":"Thromb Haemost"},{"key":"2019092417243519000_59.5.1333.7","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111931"},{"key":"2019092417243519000_59.5.1333.8","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.87.6.434"},{"key":"2019092417243519000_59.5.1333.9","doi-asserted-by":"publisher","DOI":"10.1172\/JCI6869"},{"key":"2019092417243519000_59.5.1333.10","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(92)90028-7"},{"key":"2019092417243519000_59.5.1333.11","doi-asserted-by":"crossref","first-page":"10931","DOI":"10.1016\/S0021-9258(19)49853-0","article-title":"Angiogenesis.","volume":"267","author":"Folkman","year":"1992","journal-title":"J Biol Chem"},{"key":"2019092417243519000_59.5.1333.12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512283332608"},{"key":"2019092417243519000_59.5.1333.13","doi-asserted-by":"crossref","first-page":"6346","DOI":"10.1016\/S0021-9258(19)39332-9","article-title":"Selective inhibition of integrin function by antibodies specific to ligand-occupied receptor conformers.","volume":"265","author":"Frelinger","year":"1990","journal-title":"J Biol Chem"},{"key":"2019092417243519000_59.5.1333.14","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1126\/science.270.5241.1500","article-title":"Definition of two angiogenic pathways by distinct \u03b1v integrins.","volume":"270","author":"Friedlander","year":"1995","journal-title":"Science (Wash DC)"},{"key":"2019092417243519000_59.5.1333.15","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-195-43129B"},{"key":"2019092417243519000_59.5.1333.16","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90945-8"},{"key":"2019092417243519000_59.5.1333.17","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0031-6997(24)01448-0","article-title":"Angiogenesis potentials for pharmacological intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation.","volume":"52","author":"Griffioen","year":"2000","journal-title":"Pharmacol Rev"},{"key":"2019092417243519000_59.5.1333.18","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80108-7"},{"key":"2019092417243519000_59.5.1333.19","unstructured":"Huang TF Ouyang C Teng CM (1990) Rhodostomin, a snake venom peptide and its fragment inhibit platelet aggregation by acting as fibrinogen receptor antagonist. 11th International Congress on Thrombosis; Ljubljana, Yugoslavia; 1990 June 24\u201328. Abstract 141."},{"key":"2019092417243519000_59.5.1333.20","doi-asserted-by":"publisher","DOI":"10.1007\/s000180050181"},{"key":"2019092417243519000_59.5.1333.21","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90115-S"},{"key":"2019092417243519000_59.5.1333.22","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107470"},{"key":"2019092417243519000_59.5.1333.23","first-page":"3754","article-title":"A novel disintegrin salmosin inhibits tumor angiogenesis.","volume":"59","author":"Kang","year":"1999","journal-title":"Cancer Res"},{"key":"2019092417243519000_59.5.1333.24","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2000.3130"},{"key":"2019092417243519000_59.5.1333.25","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.4.10.973"},{"key":"2019092417243519000_59.5.1333.26","doi-asserted-by":"publisher","DOI":"10.1016\/S0958-1669(99)00033-6"},{"key":"2019092417243519000_59.5.1333.27","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.121.1.163"},{"key":"2019092417243519000_59.5.1333.28","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1182\/blood.V93.3.1038","article-title":"Antineoplastic urinary protein inhibits Kaposi's sarcoma and angiogenesis in vitro and in vivo.","volume":"92","author":"Masood","year":"1999","journal-title":"Blood"},{"key":"2019092417243519000_59.5.1333.29","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0215(20000901)87:5<716::AID-IJC14>3.0.CO;2-R"},{"key":"2019092417243519000_59.5.1333.30","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81848-6"},{"key":"2019092417243519000_59.5.1333.31","first-page":"519","article-title":"A simple, quantitative method for assessing angiogenesis and anti-angiogenic agents using reconstituted basement membrane, heparin and fibroblast growth factor.","volume":"67","author":"Passaniti","year":"1992","journal-title":"Lab Invest"},{"key":"2019092417243519000_59.5.1333.32","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.6.10.1349"},{"key":"2019092417243519000_59.5.1333.33","first-page":"5209","article-title":"Antivascular endothelial growth factor receptor (fetal liver kinase I) monoclonal antibody inhibits angiogenesis and growth of several mouse and human tumor.","volume":"59","author":"Prewett","year":"1999","journal-title":"Cancer Res"},{"key":"2019092417243519000_59.5.1333.34","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1996.0319"},{"key":"2019092417243519000_59.5.1333.35","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0021-9258(18)54042-4","article-title":"Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.","volume":"268","author":"Scarborough","year":"1993","journal-title":"J Biol Chem"},{"key":"2019092417243519000_59.5.1333.36","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1111\/j.1349-7006.1992.tb01995.x","article-title":"Triflavin, an Arg-Gly-Asp-containing antiplatelet peptide inhibits cell-substratum adhesion and melanoma cell-induced lung colonization.","volume":"83","author":"Sheu","year":"1992","journal-title":"Jpn J Cancer Res"},{"key":"2019092417243519000_59.5.1333.37","doi-asserted-by":"publisher","DOI":"10.1016\/0962-8924(96)84942-7"},{"key":"2019092417243519000_59.5.1333.38","doi-asserted-by":"crossref","first-page":"3268","DOI":"10.1182\/blood.V92.9.3268","article-title":"Accutin, a new disintegrin, inhibits angiogenesis in vitro and in vivo by acting as integrin \u03b1v\u03b23 antagonist and inducing apoptosis.","volume":"92","author":"Yeh","year":"1998","journal-title":"Blood"},{"key":"2019092417243519000_59.5.1333.39","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1999.4560"},{"key":"2019092417243519000_59.5.1333.40","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009059210733"},{"key":"2019092417243519000_59.5.1333.41","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006457903545"}],"container-title":["Molecular Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/mol.59.5.1333","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T14:06:22Z","timestamp":1751205982000},"score":1,"resource":{"primary":{"URL":"http:\/\/molpharm.aspetjournals.org\/lookup\/doi\/10.1124\/mol.59.5.1333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5,1]]},"references-count":41,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2001,5,1]]},"published-print":{"date-parts":[[2001,5,1]]}},"alternative-id":["10.1124\/mol.59.5.1333"],"URL":"https:\/\/doi.org\/10.1124\/mol.59.5.1333","relation":{},"ISSN":["0026-895X","1521-0111"],"issn-type":[{"value":"0026-895X","type":"print"},{"value":"1521-0111","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5,1]]}}}