{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:53:30Z","timestamp":1791996810237,"version":"4.4.0"},"reference-count":546,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["pharmrev.aspetjournals.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pharmacological Reviews"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1124\/pr.57.4.3","type":"journal-article","created":{"date-parts":[[2005,12,28]],"date-time":"2005-12-28T18:33:15Z","timestamp":1135794795000},"page":"585-630","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":846,"title":["Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications"],"prefix":"10.1016","volume":"57","author":[{"given":"Lingyun","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1124\/pr.57.4.3_REF1","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.2174\/1381612033453758","article-title":"Therapeutic applications of human heme oxygenase gene transfer and gene therapy","volume":"9","author":"Abraham","year":"2003","journal-title":"Curr Pharm Des"},{"key":"10.1124\/pr.57.4.3_REF2","first-page":"895","article-title":"Differential effect of cobalt protoporphyrin on distributions of heme oxygenase in renal structure and on blood pressure in SHR","volume":"48","author":"Abraham","year":"2002","journal-title":"Cell Mol Biol"},{"key":"10.1124\/pr.57.4.3_REF3","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000154819","article-title":"The biological significance and physiological role of heme oxygenase","volume":"6","author":"Abraham","year":"1996","journal-title":"Cell Physiol Biochem"},{"key":"10.1124\/pr.57.4.3_REF4","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/0020-711X(88)90093-6","article-title":"The physiological significance of heme oxygenase","volume":"20","author":"Abraham","year":"1988","journal-title":"Int J Biochem"},{"key":"10.1124\/pr.57.4.3_REF5","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1002\/jcb.10736","article-title":"Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells","volume":"90","author":"Abraham","year":"2003","journal-title":"J Cell Biochem"},{"key":"10.1124\/pr.57.4.3_REF6","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1172\/JCI927","article-title":"Heme oxygenase-1 inhibits human myometrial contractility via carbon monoxide and is upregulated by progesterone during pregnancy","volume":"101","author":"Acevedo","year":"1998","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF7","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1038\/ki.1995.414","article-title":"Induction of heme oxygenase in toxic renal injury: a protective role in cisplatin nephrotoxicity in the rat","volume":"48","author":"Agarwal","year":"1995","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF8","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1161\/01.HYP.35.3.800","article-title":"Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats: possible role in renoprotection","volume":"35","author":"Aizawa","year":"2000","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF9","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0021-9258(17)42211-3","article-title":"Isolation and characterization of the mouse heme oxygenase-1 gene. Distal 5\u2032 sequences are required for induction by heme or heavy metals","volume":"269","author":"Alam","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF10","doi-asserted-by":"crossref","first-page":"27694","DOI":"10.1074\/jbc.M004729200","article-title":"Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor","volume":"275","author":"Alam","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF11","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.2174\/1381612033453749","article-title":"Anti-inflammatory actions of the heme oxygenase-1 pathway","volume":"9","author":"Alcaraz","year":"2003","journal-title":"Curr Pharm Des"},{"key":"10.1124\/pr.57.4.3_REF12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0304-4165(01)00112-X","article-title":"Heme oxygenase-1 induction by nitric oxide in RAW 264.7 macrophages is upregulated by a cyclo-oxygenase-2 inhibitor","volume":"1526","author":"Alcaraz","year":"2001","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1177\/153537020322800108","article-title":"Heme oxygenase in the rat ovary: immunohistochemical localization and possible role in steroidogenesis","volume":"228","author":"Alexanderanu","year":"2003","journal-title":"Exp Biol Med"},{"key":"10.1124\/pr.57.4.3_REF14","series-title":"Carbon Monoxide (National Research Council\u2014Subcommittee on Carbon Monoxide)","first-page":"4","article-title":"Properties and reactions of carbon monoxide","author":"Allen","year":"1977"},{"key":"10.1124\/pr.57.4.3_REF15","first-page":"186","article-title":"Partition of carbon monoxide and oxygen between air and whole blood of rats, dogs and men as affected by plasma pH","volume":"10","author":"Allen","year":"1957","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"key":"10.1124\/pr.57.4.3_REF16","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1007\/s001250051256","article-title":"Morphological evidence for the existence of nitric oxide and carbon monoxide pathways in the rat islets of Langerhans: an immunocytochemical and confocal microscopic study","volume":"42","author":"Alm","year":"1999","journal-title":"Diabetologia"},{"key":"10.1124\/pr.57.4.3_REF17","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1172\/JCI7903","article-title":"Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia\/reperfusion injury","volume":"104","author":"Amersi","year":"1999","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF18","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1006\/taap.1994.1193","article-title":"Gas uptake studies of deuterium isotope effects on dichloromethane metabolism in female B6C3F1 mice in vivo","volume":"128","author":"Andersen","year":"1994","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF19","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1080\/000164802320396312","article-title":"Heme oxygenase and nitric oxide synthase in human middle ear epithelium indicates local carbon monoxide and nitric oxide production","volume":"122","author":"Andersson","year":"2002","journal-title":"Acta Otolaryngol"},{"key":"10.1124\/pr.57.4.3_REF20","first-page":"974","article-title":"Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells","volume":"51","author":"Applegate","year":"1991","journal-title":"Cancer Res"},{"key":"10.1124\/pr.57.4.3_REF21","doi-asserted-by":"crossref","first-page":"H2055","DOI":"10.1152\/ajpheart.01084.2001","article-title":"Heme oxygenase activity in placenta: direct dependence on oxygen availability","volume":"282","author":"Appleton","year":"2002","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF22","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0003-9861(75)90390-2","article-title":"Participation of cytochrome b5 in the NADPH oxidation reaction. The evidence for two cytochromes b5 in liver microsomes","volume":"166","author":"Archakov","year":"1975","journal-title":"Arch Biochem Biophys"},{"key":"10.1124\/pr.57.4.3_REF23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0887-2333(01)00094-7","article-title":"Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation","volume":"16","author":"Archakov","year":"2002","journal-title":"Toxicol In Vitro"},{"key":"10.1124\/pr.57.4.3_REF24","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1001\/archsurg.1997.01430360098018","article-title":"Carbon monoxide contributes to the cytokine-induced inhibition of surfactant synthesis by human type II pneumocytes","volume":"132","author":"Arias-Diaz","year":"1997","journal-title":"Arch Surg"},{"key":"10.1124\/pr.57.4.3_REF25","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1006\/exnr.2001.7781","article-title":"Carbon monoxide and nitric oxide: interacting messengers in muscarinic signaling to the brain\u2019s circadian clock","volume":"171","author":"Artinian","year":"2001","journal-title":"Exp Neurol"},{"key":"10.1124\/pr.57.4.3_REF26","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.1469-7793.1999.747ad.x","article-title":"Contribution of Ca2+-activated K+ channels and non-selective cation channels to membrane potential of pulmonary arterial smooth muscle cells of the rabbit","volume":"514","author":"Bae","year":"1999","journal-title":"J Physiol (Lond)"},{"key":"10.1124\/pr.57.4.3_REF27","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1096\/fj.03-0032fje","article-title":"Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic\/reperfused mouse myocardium","volume":"17","author":"Bak","year":"2003","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF28","doi-asserted-by":"crossref","first-page":"3579","DOI":"10.1073\/pnas.0637295100","article-title":"Dealing with iron: common structural principles in proteins that transport iron and heme","volume":"100","author":"Baker","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF29","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1172\/JCI106841","article-title":"Metabolic regulation of heme catabolism and bilirubin production. Hormonal control of hepatic heme oxygenase activity","volume":"51","author":"Bakken","year":"1972","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF30","doi-asserted-by":"crossref","first-page":"32009","DOI":"10.1074\/jbc.273.48.32009","article-title":"S-Nitrosoglutathione, a product of the reaction between peroxynitrite and glutathione that generates nitric oxide","volume":"273","author":"Balazy","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF31","doi-asserted-by":"crossref","first-page":"18148","DOI":"10.1016\/S0021-9258(19)37165-0","article-title":"Ferritin: a cytoprotective antioxidant stratagem of endothelium","volume":"267","author":"Balla","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF32","first-page":"648","article-title":"Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species","volume":"64","author":"Balla","year":"1991","journal-title":"Lab Investig"},{"key":"10.1124\/pr.57.4.3_REF33","doi-asserted-by":"crossref","first-page":"9285","DOI":"10.1073\/pnas.90.20.9285","article-title":"Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage","volume":"90","author":"Balla","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF34","doi-asserted-by":"crossref","first-page":"L321","DOI":"10.1152\/ajplung.1995.268.2.L321","article-title":"Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo","volume":"268","author":"Balla","year":"1995","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1124\/pr.57.4.3_REF35","doi-asserted-by":"crossref","first-page":"16093","DOI":"10.1073\/pnas.252626999","article-title":"Biliverdin reductase: a major physiologic cytoprotectant","volume":"99","author":"Baranano","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF36","doi-asserted-by":"crossref","first-page":"15166","DOI":"10.1074\/jbc.275.20.15166","article-title":"A mammalian iron ATPase induced by iron","volume":"275","author":"Baranano","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF37","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/S0002-9440(10)65182-6","article-title":"Hemeoxygenase and nitric oxide synthase do not maintain human uterine quiescence during pregnancy","volume":"155","author":"Barber","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1124\/pr.57.4.3_REF38","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1096\/fj.00-0376com","article-title":"Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO-2 in preeclampsia and fetal growth restriction","volume":"15","author":"Barber","year":"2001","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF39","doi-asserted-by":"crossref","first-page":"H1459","DOI":"10.1152\/ajpheart.00369.2004","article-title":"The permissive role of endothelial NO in CO-induced cerebrovascular dilation","volume":"287","author":"Barkoudah","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF40","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1089\/152308602760598891","article-title":"Heme oxygenase-1: redox regulation and role in the hepatic response to oxidative stress","volume":"4","author":"Bauer","year":"2003","journal-title":"Antioxid Redox Signal"},{"key":"10.1124\/pr.57.4.3_REF41","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1073\/pnas.87.4.1620","article-title":"Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide","volume":"87","author":"Beckman","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF42","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0165-3806(97)00169-7","article-title":"Developmental expression of heme oxygenase-1 (HSP32) in rat brain: an immunocytochemical study","volume":"105","author":"Bergeron","year":"1998","journal-title":"Brain Res Dev Brain Res"},{"key":"10.1124\/pr.57.4.3_REF43","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3109\/03602539308993973","article-title":"Chemistry and biology of heme. Effect of metal salts, organometals, and metalloporphyrins on heme synthesis and catabolism, with special reference to clinical implications and interactions with cytochrome P-450","volume":"25","author":"Beri","year":"1993","journal-title":"Drug Metab Rev"},{"key":"10.1124\/pr.57.4.3_REF44","series-title":"Lecons Sur les Effets des Substances Toxiques et Medicamenteuses","author":"Bernard","year":"1857"},{"key":"10.1124\/pr.57.4.3_REF45","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s004010000202","article-title":"Long-term expression of heme oxygenase-1 (HO-1, HSP-32) following focal cerebral infarctions and traumatic brain injury in humans","volume":"100","author":"Beschorner","year":"2000","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1124\/pr.57.4.3_REF46","doi-asserted-by":"crossref","first-page":"12821","DOI":"10.1021\/bi0204443","article-title":"Kinetic barriers to the folding of horse cytochrome c in the reduced state","volume":"41","author":"Bhuyan","year":"2002","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/exnr.2000.7456","article-title":"Heme oxygenase-1 (HSP-32) and heme oxygenase-2 induction in neurons and glial cells of cerebral regions and its relation to iron accumulation after focal cortical photothrombosis","volume":"168","author":"Bidmon","year":"2001","journal-title":"Exp Neurol"},{"key":"10.1124\/pr.57.4.3_REF48","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1017\/S0952523800174061","article-title":"Direct imaging of NMDA-stimulated nitric oxide production in the retina","volume":"17","author":"Blute","year":"2000","journal-title":"Vis Neurosci"},{"key":"10.1124\/pr.57.4.3_REF49","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0896-6273(03)00596-8","article-title":"Carbon monoxide neurotransmission activated by CK2 phosphorylation of heme oxygenase-2","volume":"40","author":"Boehning","year":"2003","journal-title":"Neuron"},{"key":"10.1124\/pr.57.4.3_REF50","doi-asserted-by":"crossref","first-page":"30927","DOI":"10.1074\/jbc.C400222200","article-title":"Heme oxygenase-2 is activated by calcium-calmodulin","volume":"279","author":"Boehning","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF51","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1161\/hy0202.103420","article-title":"Regulation of cyclooxygenase-and cytochrome p450-derived eicosanoids by heme oxygenase in the rat kidney","volume":"39","author":"Botros","year":"2002","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF52","doi-asserted-by":"crossref","first-page":"32688","DOI":"10.1074\/jbc.275.42.32688","article-title":"Nitric oxide-inducible expression of heme oxygenase-1 in human cells. Translation-independent stabilization of the mRNA and evidence for direct action of nitric oxide","volume":"275","author":"Bouton","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF53","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1161\/01.STR.25.3.639","article-title":"Effect of carbon monoxide on rabbit cerebral arteries","volume":"25","author":"Brian","year":"1994","journal-title":"Stroke"},{"key":"10.1124\/pr.57.4.3_REF54","doi-asserted-by":"crossref","first-page":"17950","DOI":"10.1074\/jbc.M108317200","article-title":"Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis","volume":"277","author":"Brouard","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF55","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1084\/jem.192.7.1015","article-title":"Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis","volume":"192","author":"Brouard","year":"2000","journal-title":"J Exp Med"},{"key":"10.1124\/pr.57.4.3_REF56","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1172\/JCI115633","article-title":"Recovery of energy metabolism in rat brain after carbon monoxide hypoxia","volume":"89","author":"Brown","year":"1992","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF57","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1432-1033.1990.tb19276.x","article-title":"Activation of soluble guanylate cyclase by carbon monoxide and inhibition by superoxide anion","volume":"192","author":"Brune","year":"1990","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF58","first-page":"497","article-title":"Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase","volume":"32","author":"Brune","year":"1987","journal-title":"Mol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF59","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/35035093","article-title":"A vertebrate globin expressed in the brain","volume":"407","author":"Burmester","year":"2000","journal-title":"Nature (Lond)"},{"key":"10.1124\/pr.57.4.3_REF60","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/nm0198-084","article-title":"Ejaculatory abnormalities in mice with targeted disruption of the gene for heme oxygenase-2","volume":"4","author":"Burnett","year":"1998","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF61","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1038\/sj.bjp.0702143","article-title":"Effects of prenatal exposure to low concentrations of carbon monoxide on sexual behaviour and mesolimbic dopaminergic function in rat offspring","volume":"125","author":"Cagiano","year":"1998","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF62","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/01902149609074015","article-title":"Low dose carbon monoxide does not reduce vasoconstriction in isolated rat lungs","volume":"22","author":"Cantrell","year":"1995","journal-title":"Exp Lung Res"},{"key":"10.1124\/pr.57.4.3_REF63","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1017\/S0952523800173018","article-title":"Localization of heme oxygenase-2 and modulation of cGMP levels by carbon monoxide and\/or nitric oxide in the retina","volume":"17","author":"Cao","year":"2000","journal-title":"Vis Neurosci"},{"key":"10.1124\/pr.57.4.3_REF64","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0006-8993(03)03346-8","article-title":"Inhibitors of nitric oxide synthase block carbon monoxide-induced increases in cGMP in retina","volume":"988","author":"Cao","year":"2003","journal-title":"Brain Res"},{"key":"10.1124\/pr.57.4.3_REF65","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1021\/bi0483211","article-title":"Complexes of horseradish peroxidase with formate, acetate and carbon monoxide","volume":"44","author":"Carlsson","year":"2005","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF66","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/BF01973698","article-title":"Changes in peripheral nervous system activity produced in rats by prenatal exposure to carbon monoxide","volume":"67","author":"Carratu","year":"1993","journal-title":"Arch Toxicol"},{"key":"10.1124\/pr.57.4.3_REF67","doi-asserted-by":"crossref","first-page":"L693","DOI":"10.1152\/ajplung.00211.2001","article-title":"Carbon monoxide promotes hypoxic pulmonary vascular remodeling","volume":"282","author":"Carraway","year":"2002","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1124\/pr.57.4.3_REF68","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1136\/gut.47.6.771","article-title":"Inhibition of inducible nitric oxide synthase in the human intestinal epithelial cell line, DLD-1, by the inducers of heme oxygenase 1, bismuth salts, heme and nitric oxide donors","volume":"47","author":"Cavicchi","year":"2000","journal-title":"Gut"},{"key":"10.1124\/pr.57.4.3_REF69","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.1523\/JNEUROSCI.23-09-03689.2003","article-title":"Heme oxygenase-2 protects against lipid peroxidation-mediated cell loss and impaired motor recovery after traumatic brain injury","volume":"23","author":"Chang","year":"2003","journal-title":"J Neurosci"},{"key":"10.1124\/pr.57.4.3_REF70","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1034\/j.1600-6143.2002.20702.x","article-title":"Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection","volume":"2","author":"Chauveau","year":"2002","journal-title":"Am J Transplant"},{"key":"10.1124\/pr.57.4.3_REF71","first-page":"609","article-title":"Nitric oxide induces heme oxygenase-1 via mitogen-activated protein kinases ERK and p38","volume":"46","author":"Chen","year":"2000","journal-title":"Cell Mol Biol"},{"key":"10.1124\/pr.57.4.3_REF72","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1161\/01.CIR.91.9.2306","article-title":"Vascular smooth muscle cell heme oxygenase generate guanyl cyclase-stimulatory carbon monoxide","volume":"91","author":"Christodoulides","year":"1995","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF73","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1161\/01.RES.86.12.1224","article-title":"Prevention of hypoxia-induced pulmonary hypertension by enhancement of endogenous heme oxygenase-1 in the rat","volume":"86","author":"Christou","year":"2000","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.1992.tb05278.x","article-title":"Carbon monoxide-binding properties of the cytochrome bo quinol oxidase complex in Escherichia coli are changed by copper deficiency in continuous culture","volume":"73","author":"Ciccognani","year":"1992","journal-title":"FEMS Microbiol Lett"},{"key":"10.1124\/pr.57.4.3_REF75","doi-asserted-by":"crossref","first-page":"H643","DOI":"10.1152\/ajpheart.2000.278.2.H643","article-title":"Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction","volume":"278","author":"Clark","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF76","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1161\/01.RES.0000084381.86567.08","article-title":"Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule","volume":"93","author":"Clark","year":"2003","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF77","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1056\/NEJM197009032831004","article-title":"Enhancement by phenobarbitol and diphenylhydantoin of carbon monoxide production in normal man","volume":"283","author":"Coburn","year":"1970","journal-title":"N Engl J Med"},{"key":"10.1124\/pr.57.4.3_REF78","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1749-6632.1970.tb49768.x","article-title":"The carbon monoxide body stores","volume":"174","author":"Coburn","year":"1970","journal-title":"Ann NY Acad Sci"},{"key":"10.1124\/pr.57.4.3_REF79","first-page":"439","article-title":"Carbon monoxide toxicity","volume":"4","author":"Coburn","year":"1987","journal-title":"Handbook Physiol"},{"key":"10.1124\/pr.57.4.3_REF80","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1152\/ajplegacy.1971.220.1.66","article-title":"Myoglobin oxygen tension determined from measurements of carboxymyglobin in skeletal muscle","volume":"220","author":"Coburn","year":"1971","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF81","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1172\/JCI104994","article-title":"Effect of erythrocyte destruction on carbon monoxide production in man","volume":"43","author":"Coburn","year":"1965","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF82","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1172\/JCI105360","article-title":"Endogenous carbon monoxide production in patients with hemolytic anemia","volume":"45","author":"Coburn","year":"1966","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF83","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1161\/01.RES.62.3.471","article-title":"Further evidence implicating a cytochrome P450 mediated reaction in the contractile tension of the lamb ductus arteriosus","volume":"62","author":"Coceani","year":"1988","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF84","first-page":"H640","article-title":"Cytochrome P450-linked monooxygenase: involvement in the lamb ductus arteriosus","volume":"246","author":"Coceani","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF85","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1007\/BF03401995","article-title":"RDP1258, a new rationally designed immunosuppressive peptide, prolongs allograft survival in rats: analysis of its mechanism of action","volume":"5","author":"Cuturi","year":"1999","journal-title":"Mol Med"},{"key":"10.1124\/pr.57.4.3_REF86","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1046\/j.1523-1755.1999.00429.x","article-title":"Nitric oxide induces heme oxygenase-1 gene expression in mesangial cells","volume":"55","author":"Datta","year":"1999","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF87","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1152\/jappl.1974.36.1.49","article-title":"Cyclic variation of rate of carbon monoxide production in normal women","volume":"36","author":"Delivoria-Papadopoulos","year":"1974","journal-title":"J Appl Physiol"},{"key":"10.1124\/pr.57.4.3_REF88","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1056\/NEJM200102223440807","article-title":"Neonatal hyperbilirubinemia","volume":"344","author":"Dennery","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1124\/pr.57.4.3_REF89","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1172\/JCI448","article-title":"Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2","volume":"101","author":"Dennery","year":"1998","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF90","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/(SICI)1097-4644(19980101)68:1<121::AID-JCB12>3.0.CO;2-K","article-title":"Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis","volume":"68","author":"Deramaudt","year":"1998","journal-title":"J Cell Biochem"},{"key":"10.1124\/pr.57.4.3_REF91","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4644(19990301)72:3<311::AID-JCB1>3.0.CO;2-G","article-title":"Upregulation of human heme oxygenase gene expression by Ets-family proteins","volume":"72","author":"Deramaudt","year":"1999","journal-title":"J Cell Biochem"},{"key":"10.1124\/pr.57.4.3_REF92","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1046\/j.1432-1327.1999.00677.x","article-title":"Interaction of heme oxgenase-2 with nitric oxide donors","volume":"264","author":"Ding","year":"1999","journal-title":"Is the oxygenase an intracelluar \u2018sink\u2019 for NO? Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF93","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1126\/science.1078456","article-title":"NPAS2: a gas-responsive transcription factor","volume":"298","author":"Dioum","year":"2002","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF94","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1038\/sj.bjc.6690624","article-title":"Induction of haem oxygenase-1 by nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth","volume":"80","author":"Doi","year":"1999","journal-title":"Br J Cancer"},{"key":"10.1124\/pr.57.4.3_REF95","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1073\/pnas.96.5.2445","article-title":"Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury","volume":"96","author":"Dore","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF96","doi-asserted-by":"crossref","first-page":"L120","DOI":"10.1152\/ajplung.00004.2002","article-title":"Chronic carbon monoxide enhanced IbTx-sensitive currents in rat resistance pulmonary artery smooth muscle cells","volume":"283","author":"Dubuis","year":"2002","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1124\/pr.57.4.3_REF97","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.cardiores.2004.11.007","article-title":"Continuous inhalation of carbon monoxide attenuates hypoxic pulmonary hypertension development presumably through activation of BKCa channels","volume":"65","author":"Dubuis","year":"2005","journal-title":"Cardiovasc Res"},{"key":"10.1124\/pr.57.4.3_REF98","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/89068","article-title":"Heme oxygenase-1 protects against vascular constriction and proliferation","volume":"7","author":"Duckers","year":"2001","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF99","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1563-2563.2002.02028.x","article-title":"Angiogenic gene therapy with vascular endothelial growth factor: hope or hype?","volume":"34","author":"Dulak","year":"2002","journal-title":"Eur Surg"},{"key":"10.1124\/pr.57.4.3_REF100","series-title":"Carbon Monoxide and Cardiovascular Functions","first-page":"45","article-title":"Carbon monoxide and vascular smooth muscle cell growth","author":"Durante","year":"2002"},{"key":"10.1124\/pr.57.4.3_REF101","first-page":"H317","article-title":"cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle","volume":"273","author":"Durante","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF102","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1161\/01.RES.80.4.557","article-title":"Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells","volume":"80","author":"Durante","year":"1997","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF103","doi-asserted-by":"crossref","first-page":"2666","DOI":"10.1161\/01.ATV.19.11.2666","article-title":"Platelet-derived growth factor stimulates heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells","volume":"19","author":"Durante","year":"1999","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1124\/pr.57.4.3_REF104","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1073\/pnas.88.3.688","article-title":"Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron","volume":"88","author":"Eisenstein","year":"1991","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF105","doi-asserted-by":"crossref","first-page":"8922","DOI":"10.1074\/jbc.273.15.8922","article-title":"Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases","volume":"273","author":"Elbirt","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF106","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1161\/01.HYP.17.6.776","article-title":"Chronic treatment with tin normalizes blood pressure in spontaneously hypertensive rats","volume":"17","author":"Escalante","year":"1991","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF107","series-title":"Biological Effects of Carbon Monoxide","first-page":"218","article-title":"Factors influencing the inhibitory reactions","author":"Estabrook","year":"1980"},{"key":"10.1124\/pr.57.4.3_REF108","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1111\/j.1471-4159.1992.tb09373.x","article-title":"Normal and heat-induced patterns of expression of heme oxygenase-1 (HSP32) in rat brain: hyperthermia causes rapid induction of mRNA and protein","volume":"58","author":"Ewing","year":"1992","journal-title":"J Neurochem"},{"key":"10.1124\/pr.57.4.3_REF109","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/1044-7431(92)90068-D","article-title":"In situ hybridization and immunohistochemical localization of heme oxygenase-2 mRNA and protein in normal rat brain: differential distribution of isoenzyme 1 and 2","volume":"3","author":"Ewing","year":"1992","journal-title":"Mol Cell Neurosci"},{"key":"10.1124\/pr.57.4.3_REF110","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1210\/endo.136.5.7720678","article-title":"Distribution of constitutive (HO-2) and heat-inducible (HO-1) heme oxygenase isozymes in rat testes: HO-2 displays stage-specific expression in germ cells","volume":"136","author":"Ewing","year":"1995","journal-title":"Endocrinology"},{"key":"10.1124\/pr.57.4.3_REF111","first-page":"408","article-title":"Induction of heart heme oxygenase-1 (HSP32) by hyperthermia: possible role in stress-mediated elevation of cyclic 3\u2032:5\u2032-guanosine monophosphate","volume":"271","author":"Ewing","year":"1994","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/pr.57.4.3_REF112","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1172\/JCI3862","article-title":"The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia","volume":"103","author":"Fagan","year":"1999","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF113","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1023\/B:APPT.0000012119.83734.4e","article-title":"Antiapoptotic role of heme oxygenase (HO) and the potential of HO as a target in anticancer treatment","volume":"9","author":"Fang","year":"2004","journal-title":"Apoptosis"},{"key":"10.1124\/pr.57.4.3_REF114","first-page":"3567","article-title":"In vivo antitumor activity of pegylated zinc protoporphyrin: Targeted inhibition of heme oxygenase in solid tumor","volume":"63","author":"Fang","year":"2003","journal-title":"Cancer Res"},{"key":"10.1124\/pr.57.4.3_REF115","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1152\/ajplegacy.1932.102.2.393","article-title":"The burning of carbon monoxide by heart and skeletal muscle","volume":"102","author":"Fenn","year":"1932","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF116","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/S0168-8278(01)00010-1","article-title":"Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity","volume":"34","author":"Fernandez","year":"2001","journal-title":"J Hepatol"},{"key":"10.1124\/pr.57.4.3_REF117","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/11072","article-title":"Haem oxygenase-1 prevents cell death by regulating cellular iron","volume":"1","author":"Ferris","year":"1999","journal-title":"Nat Cell Biol"},{"key":"10.1124\/pr.57.4.3_REF118","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1165\/ajrcmb.20.4.3477","article-title":"Iron regulates hyperoxiadependent human heme oxygenase 1 gene expression in pulmonary endothelial cells","volume":"20","author":"Fogg","year":"1999","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1124\/pr.57.4.3_REF119","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/sj.bjp.0705825","article-title":"Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule","volume":"142","author":"Foresti","year":"2004","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF120","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1042\/bj20021516","article-title":"Haem and nitric oxide: synergism in the modulation of the endothelial haem oxygenase-1 pathway","volume":"372","author":"Foresti","year":"2003","journal-title":"Biochem J"},{"key":"10.1124\/pr.57.4.3_REF121","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/10715769900301031","article-title":"The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis","volume":"31","author":"Foresti","year":"1999","journal-title":"Free Radic Res"},{"key":"10.1124\/pr.57.4.3_REF122","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1042\/bj3390729","article-title":"Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis","volume":"339","author":"Foresti","year":"1999","journal-title":"Biochem J"},{"key":"10.1124\/pr.57.4.3_REF123","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1749-6632.1970.tb49789.x","article-title":"Carbon monoxide and the partial pressure of oxygen in tissue","volume":"174","author":"Forster","year":"1970","journal-title":"Ann NY Acad Sci"},{"key":"10.1124\/pr.57.4.3_REF124","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/1097-4652(200010)185:1<80::AID-JCP7>3.0.CO;2-W","article-title":"Role of heme oxygenase-1 in the regulation of manganese superoxide dismutase gene expression in oxidatively challenged astroglia","volume":"185","author":"Frankel","year":"2000","journal-title":"J Cell Physiol"},{"key":"10.1124\/pr.57.4.3_REF125","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1124\/mol.53.1.123","article-title":"Mechanism of YC-1-induced activation of soluble guanylyl cyclase","volume":"53","author":"Friebe","year":"1998","journal-title":"Mol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF126","doi-asserted-by":"crossref","first-page":"6863","DOI":"10.1002\/j.1460-2075.1996.tb01078.x","article-title":"Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme","volume":"15","author":"Friebe","year":"1996","journal-title":"EMBO (Eur Mol Biol Organ) J"},{"key":"10.1124\/pr.57.4.3_REF127","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1161\/01.ATV.0000142364.85911.0e","article-title":"Carbon monoxide protects against cardiac ischemia-reperfusion injury in vivo via MAPK and Akt-eNOS pathways","volume":"24","author":"Fujimoto","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1124\/pr.57.4.3_REF128","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/87929","article-title":"Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis","volume":"7","author":"Fujita","year":"2001","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF129","first-page":"52","article-title":"Endothelium-dependent and -independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light","volume":"28","author":"Furchgott","year":"1991","journal-title":"Blood Vessels"},{"key":"10.1124\/pr.57.4.3_REF130","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s00424-002-1003-x","article-title":"Role of constitutively expressed heme oxygenase-2 in the regulation of guinea pig coronary artery tone","volume":"446","author":"Gagov","year":"2003","journal-title":"Pflueg Arch Eur J Physiol"},{"key":"10.1124\/pr.57.4.3_REF131","first-page":"326","article-title":"Portal hypertension: state of the art","volume":"31","author":"Gatta","year":"1999","journal-title":"Ital J Gastroenterol Hepatol"},{"key":"10.1124\/pr.57.4.3_REF132","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1152\/jn.2000.83.1.116","article-title":"Nitric oxide and carbon monoxide modulate oscillations of olfactory interneurons in a terrestrial mollusk","volume":"83","author":"Gelperin","year":"2000","journal-title":"J Neurophysiol"},{"key":"10.1124\/pr.57.4.3_REF133","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0014-5793(81)80429-2","article-title":"Soluble guanylate cyclase purified from bovine lung contains heme and copper","volume":"132","author":"Gerzer","year":"1981","journal-title":"FEBS Lett"},{"key":"10.1124\/pr.57.4.3_REF134","doi-asserted-by":"crossref","first-page":"30417","DOI":"10.1074\/jbc.C300203200","article-title":"A globin in the nucleus!","volume":"278","author":"Geuens","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF135","doi-asserted-by":"crossref","first-page":"10228","DOI":"10.1016\/S0021-9258(18)67514-3","article-title":"A kinetic description of ligand binding to sperm whale myoglobin","volume":"261","author":"Gibson","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF136","first-page":"965","article-title":"Zinc protoporphyrin-IX blocks the effects of metabotropic glutamate receptor activation in the rat nucleus tractus solitarii","volume":"43","author":"Glaum","year":"1993","journal-title":"Mol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF137","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1172\/JCI1324","article-title":"Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation","volume":"101","author":"Goda","year":"1998","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF138","doi-asserted-by":"crossref","first-page":"4355","DOI":"10.1016\/S0021-9258(17)41787-X","article-title":"Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin","volume":"269","author":"Goldberg","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF139","first-page":"293","article-title":"Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein","volume":"49","author":"Graser","year":"1990","journal-title":"Biomed Biochim Acta"},{"key":"10.1124\/pr.57.4.3_REF140","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1111\/j.1469-7793.2001.00855.x","article-title":"The shaping of nitric oxide signals by a cellular sink","volume":"536","author":"Griffiths","year":"2001","journal-title":"J Physiol (Lond)"},{"key":"10.1124\/pr.57.4.3_REF141","first-page":"208","article-title":"Inducible nitric oxide synthase and heme oxygenase-1 in rat heart: direct effect of chronic exposure to hypoxia","volume":"33","author":"Grilli","year":"2003","journal-title":"Ann Clin Lab Sci"},{"key":"10.1124\/pr.57.4.3_REF142","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0165-6147(97)90622-2","article-title":"Pitfalls using metalloporphyrins in carbon monoxide research","volume":"18","author":"Grundemar","year":"1997","journal-title":"Trends Pharmacol Sci"},{"key":"10.1124\/pr.57.4.3_REF143","doi-asserted-by":"crossref","first-page":"3633","DOI":"10.1021\/bi00610a033","article-title":"Destruction of heme and hemoproteins mediated by liver microsomal reduced NADP-cytochrome P450 reductase","volume":"17","author":"Guengerich","year":"1978","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF144","doi-asserted-by":"crossref","first-page":"994","DOI":"10.2337\/diabetes.51.4.994","article-title":"Carbon monoxide protects pancreatic \u03b2-cells from apoptosis and improves islet function\/survival after transplantation","volume":"51","author":"Gunther","year":"2002","journal-title":"Diabetes"},{"key":"10.1124\/pr.57.4.3_REF145","doi-asserted-by":"crossref","first-page":"H1649","DOI":"10.1152\/ajpheart.00971.2003","article-title":"Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo","volume":"286","author":"Guo","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF146","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1113\/jphysiol.1895.sp000562","article-title":"The relation of the action of carbonic oxide to oxygen tension","volume":"18","author":"Haldane","year":"1895","journal-title":"J Physiol (Lond)"},{"key":"10.1124\/pr.57.4.3_REF147","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1113\/jphysiol.1896.sp000634","article-title":"The oxygen tension of arterial blood","volume":"20","author":"Haldane","year":"1896","journal-title":"J Physiol (Lond)"},{"key":"10.1124\/pr.57.4.3_REF148","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1113\/jphysiol.1959.sp006213","article-title":"The time course of the effects of carbon monoxide on visual thresholds","volume":"146","author":"Halperin","year":"1959","journal-title":"J Physiol (Lond)"},{"key":"10.1124\/pr.57.4.3_REF149","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1038\/3982","article-title":"Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes","volume":"4","author":"Hancock","year":"1998","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF150","doi-asserted-by":"crossref","first-page":"5047","DOI":"10.1074\/jbc.274.8.5047","article-title":"Hypoxia posttranslationally activates iron-regulatory protein 2","volume":"274","author":"Hanson","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF151","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0005-2728(96)00022-9","article-title":"The ferritins: molecular properties, iron storage function and cellular regulation","volume":"1275","author":"Harrison","year":"1996","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF152","doi-asserted-by":"crossref","first-page":"L980","DOI":"10.1152\/ajplung.1997.273.5.L980","article-title":"Regulation of heme oxygenase-1 gene expression in vascular smooth muscle cells by nitric oxide","volume":"273","author":"Hartsfield","year":"1997","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1124\/pr.57.4.3_REF153","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1097\/00001756-199703030-00045","article-title":"Heme oxygenase-2 and nitric oxide synthase in guinea-pig intracardiac neurones","volume":"8","author":"Hassall","year":"1997","journal-title":"Neuroreport"},{"key":"10.1124\/pr.57.4.3_REF154","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1046\/j.1523-1755.2000.00150.x","article-title":"Angiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro","volume":"58","author":"Haugen","year":"2000","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF154a","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.gene.2004.04.002","article-title":"Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene","volume":"336","author":"Hayashi","year":"2004","journal-title":"Gene"},{"key":"10.1124\/pr.57.4.3_REF156","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1161\/01.RES.85.8.663","article-title":"Induction of heme oxygenase-1 suppresses venular leukocyte adhesion elicited by oxidative stress: role of bilirubin generated by the enzyme","volume":"85","author":"Hayashi","year":"1999","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF157","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/S0022-5347(05)67329-6","article-title":"Cholinergic nerves in human corpus cavernosum and spongiosum contain nitric oxide synthase and heme oxygenase","volume":"164","author":"Hedlund","year":"2000","journal-title":"J Urol"},{"key":"10.1124\/pr.57.4.3_REF158","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-3495(02)75368-X","article-title":"Transient binding of CO to Cu(B) in cytochrome c oxidase is dynamically linked to structural changes around a carboxyl group: a time-resolved step-scan Fourier transform infrared investigation","volume":"82","author":"Heitbrink","year":"2002","journal-title":"Biophys J"},{"key":"10.1124\/pr.57.4.3_REF159","doi-asserted-by":"crossref","first-page":"C703","DOI":"10.1152\/ajpcell.1997.273.2.C703","article-title":"Occurrence and putative hormone regulatory function of a constitutive heme oxygenase in rat pancreatic islets","volume":"273","author":"Henningsson","year":"1997","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1124\/pr.57.4.3_REF160","doi-asserted-by":"crossref","first-page":"66","DOI":"10.2337\/diabetes.48.1.66","article-title":"Heme oxygenase and carbon monoxide: regulatory roles in islet hormone release: a biochemical, immunohistochemical and confocal microscopic study","volume":"48","author":"Henningsson","year":"1999","journal-title":"Diabetes"},{"key":"10.1124\/pr.57.4.3_REF161","doi-asserted-by":"crossref","first-page":"C1242","DOI":"10.1152\/ajpcell.2001.280.5.C1242","article-title":"Evaluation of heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemia","volume":"280","author":"Henningsson","year":"2001","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1124\/pr.57.4.3_REF162","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1089\/104454902753759726","article-title":"Heme oxygenase and the kidney","volume":"21","author":"Hill-Kapturczak","year":"2002","journal-title":"DNA Cell Biol"},{"key":"10.1124\/pr.57.4.3_REF163","doi-asserted-by":"crossref","first-page":"F515","DOI":"10.1152\/ajprenal.00137.2003","article-title":"An internal enhancer regulates heme- and cadmium-mediated induction of human heme oxygenase-1","volume":"285","author":"Hill-Kapturczak","year":"2003","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/pr.57.4.3_REF164","doi-asserted-by":"crossref","first-page":"40904","DOI":"10.1074\/jbc.M006621200","article-title":"Smad7-dependent regulation of heme oxygenase-1 by transforming growth factor-beta in human renal epithelial cells","volume":"275","author":"Hill-Kapturczak","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF165","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1006\/bbrc.2000.2995","article-title":"Functional analysis of heme regulatory elements of the transcriptional activator Hap1","volume":"273","author":"Hon","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF166","doi-asserted-by":"crossref","first-page":"22770","DOI":"10.1074\/jbc.274.32.22770","article-title":"The yeast heme-responsive transcriptional activator Hap1 is a preexisting dimer in the absence of heme","volume":"274","author":"Hon","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF167","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0014-5793(92)81492-5","article-title":"Resonance Raman studies of the carbonmonoxy form of catalase. Evidence for and effects of phenolate ligation","volume":"314","author":"Hu","year":"1992","journal-title":"FEBS Lett"},{"key":"10.1124\/pr.57.4.3_REF168","doi-asserted-by":"crossref","first-page":"9038","DOI":"10.1074\/jbc.274.13.9038","article-title":"Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling","volume":"274","author":"Huang","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF169","first-page":"56","article-title":"Altered expression of HO and NOS in hippocampus from spontaneously hypertensive rats","volume":"9","author":"Huang","year":"2004","journal-title":"Exp Clin Cardiol"},{"key":"10.1124\/pr.57.4.3_REF170","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/(SICI)1097-4652(199607)168:1<71::AID-JCP9>3.0.CO;2-5","article-title":"Hemopexin in the human retina: protection of the retina against hememediated toxicity","volume":"168","author":"Hunt","year":"1996","journal-title":"J Cell Physiol"},{"key":"10.1124\/pr.57.4.3_REF171","doi-asserted-by":"crossref","first-page":"13407","DOI":"10.1021\/bi00041a018","article-title":"Expression of the mRNA of heme-binding protein 23 is coordinated with that of heme oxygenase-1 by heme and heavy metals in primary rat hepatocytes and hepatoma cells","volume":"34","author":"Immenschuh","year":"1995","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF172","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1124\/mol.53.3.483","article-title":"The rat heme oxygenase-1 gene is transcriptionally induced via the protein kinase A signaling pathway in rat hepatocyte cultures","volume":"53","author":"Immenschuh","year":"1998","journal-title":"Mol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF172a","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/hep.510300142","article-title":"Up-regulation of heme-binding protein 23 (HBP23) gene expression by lipopolysaccharide is mediated via a nitric oxide-dependent signaling pathway in rat Kupffer cells","volume":"30","author":"Immenschuh","year":"1999","journal-title":"Hepatology"},{"key":"10.1124\/pr.57.4.3_REF174","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/S0896-6273(00)80103-8","article-title":"Carbon monoxide: an endogenous modulator of the nitric oxide-cyclic GMP signaling system","volume":"16","author":"Ingi","year":"1996","journal-title":"Neuron"},{"key":"10.1124\/pr.57.4.3_REF175","doi-asserted-by":"crossref","first-page":"5621","DOI":"10.1523\/JNEUROSCI.16-18-05621.1996","article-title":"The regulation of heme turnover and carbon monoxide biosynthesis in cultured primary rat olfactory receptor neurons","volume":"16","author":"Ingi","year":"1996","journal-title":"J Neurosci"},{"key":"10.1124\/pr.57.4.3_REF176","doi-asserted-by":"crossref","first-page":"8214","DOI":"10.1523\/JNEUROSCI.15-12-08214.1995","article-title":"Direct demonstration of a physiological role for carbon monoxide in olfactory receptor neurons","volume":"15","author":"Ingi","year":"1995","journal-title":"J Neurosci"},{"key":"10.1124\/pr.57.4.3_REF177","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1046\/j.1523-1755.2001.00046.x","article-title":"Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis","volume":"60","author":"Inguaggiato","year":"2001","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF178","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.2174\/1381612033453767","article-title":"Heme oxygenase-1 against vascular insufficiency: roles of atherosclerotic disorders","volume":"9","author":"Ishikawa","year":"2003","journal-title":"Curr Pharm Des"},{"key":"10.1124\/pr.57.4.3_REF179","doi-asserted-by":"crossref","first-page":"63","DOI":"10.5551\/jat1994.8.63","article-title":"Heme oxygenase as an intrinsic defense system in vascular wall: implication against atherogenesis","volume":"8","author":"Ishikawa","year":"2001","journal-title":"J Atheroscler Thromb"},{"key":"10.1124\/pr.57.4.3_REF180","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1161\/hc3901.095897","article-title":"Heme oxygenase-1 inhibits atherogenesis in Watanabe heritable hyperlipidemic rabbits","volume":"104","author":"Ishikawa","year":"2001","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF181","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1161\/01.RES.88.5.506","article-title":"Heme oxygenase-1 inhibits atherosclerotic lesion formation in LDL-receptor knockout mice","volume":"88","author":"Ishikawa","year":"2001","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF182","first-page":"H672","article-title":"Heme oxygenase-1 is upregulated in the rat heart in response to chronic administration of angiotensin II","volume":"279","author":"Ishizaka","year":"2000","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF183","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1161\/01.HYP.29.3.790","article-title":"Heme oxygenase-1 is regulated by angiotensin II in rat vascular smooth muscle cells","volume":"29","author":"Ishizaka","year":"1997","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF184","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1161\/01.CIR.96.6.1923","article-title":"Angiotensin II-induced hypertension increases heme oxygenase-1 expression in rat aorta","volume":"96","author":"Ishizaka","year":"1997","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF185","doi-asserted-by":"crossref","first-page":"13398","DOI":"10.1021\/bi00041a017","article-title":"Purification, characterization and cloning of a heme-binding protein (23 kDa) in rat liver cytosol","volume":"34","author":"Iwahara","year":"1995","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF186","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1161\/01.RES.0000036900.76780.95","article-title":"Carbon monoxide dilates cerebral arterioles by enhancing the coupling of Ca2+ sparks to Ca2+-activated K+ channels","volume":"91","author":"Jaggar","year":"2002","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF187","doi-asserted-by":"crossref","first-page":"6867","DOI":"10.1021\/bi002849y","article-title":"Characterization of a half-apo derivative of peptidylglycine monooxygenase. Insight into the reactivity of each active site copper","volume":"40","author":"Jaron","year":"2001","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF188","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1182\/blood.V100.3.879","article-title":"Pro-oxidant and cytotoxic effects of circulating heme","volume":"100","author":"Jeney","year":"2002","journal-title":"Blood"},{"key":"10.1124\/pr.57.4.3_REF189","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1161\/01.HYP.0000046923.52222.58","article-title":"Heme oxygenase inhibitor restores arteriolar nitric oxide function in Dahl rats","volume":"41","author":"Johnson","year":"2003","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF190","doi-asserted-by":"crossref","first-page":"R536","DOI":"10.1152\/ajpregu.00624.2002","article-title":"Carbon monoxide promotes endotheliumdependent constriction of isolated gracilis muscle arterioles","volume":"285","author":"Johnson","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1124\/pr.57.4.3_REF191","series-title":"Carbon Monoxide and Cardiovascular Functions","first-page":"149","article-title":"The heme-heme oxygenase-carbon monoxide system and hypertension","author":"Johnson","year":"2002"},{"key":"10.1124\/pr.57.4.3_REF192","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1161\/01.HYP.25.2.166","article-title":"A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats","volume":"25","author":"Johnson","year":"1995","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF193","doi-asserted-by":"crossref","first-page":"H1132","DOI":"10.1152\/ajpheart.1996.271.3.H1132","article-title":"Heme oxygenase substrates acutely lower blood pressure in hypertensive rats","volume":"271","author":"Johnson","year":"1996","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF194","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1161\/hc3801.095663","article-title":"Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice","volume":"104","author":"Juan","year":"2001","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF195","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1172\/JCI11218","article-title":"Carbon monoxide of vascular origin attenuates the sensitivity of renal arterial vessels to vasoconstrictors","volume":"107","author":"Kaide","year":"2001","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF196","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1096\/fj.02-0359fje","article-title":"Visualization of gaseous monoxide reception by soluble guanylate cyclase in the rat retina","volume":"17","author":"Kajimura","year":"2003","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF197","series-title":"Principles of Neural Science, 4th ed","author":"Kandel","year":"2000"},{"key":"10.1124\/pr.57.4.3_REF198","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1542\/peds.91.3.537","article-title":"Prolonged clinical use of a heme oxygenase inhibitor: hematological evidence for an inducible but reversible iron-deficiency state","volume":"91","author":"Kappas","year":"1993","journal-title":"Pediatrics"},{"key":"10.1124\/pr.57.4.3_REF199","first-page":"309","article-title":"Effects of hydroxyl radical scavengers KCN and CO on ultraviolet light-induced activation of crude soluble guanylate cyclase","volume":"10","author":"Karlsson","year":"1985","journal-title":"J Cyclic Nucleotide Protein Phosphor Res"},{"key":"10.1124\/pr.57.4.3_REF200","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0891-5849(98)00252-4","article-title":"Heme and apoprotein modi.cation of cytochrome P450 2B4 during its oxidative inactivation in monooxygenase reconstituted system","volume":"26","author":"Karuzina","year":"1999","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/pr.57.4.3_REF201","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1097\/00007890-200201270-00023","article-title":"Heme oxygenase-1 overexpression protects rat hearts from cold ischemia\/reperfusion injury via an antiapoptotic pathway","volume":"73","author":"Katori","year":"2002","journal-title":"Transplantation (Baltim)"},{"key":"10.1124\/pr.57.4.3_REF202","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1053\/hupa.2002.30217","article-title":"Heme oxygenase-1 deficiency: the first autopsy case","volume":"33","author":"Kawashima","year":"2002","journal-title":"Hum Pathol"},{"key":"10.1124\/pr.57.4.3_REF203","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1089\/104303402320138970","article-title":"Heme oxygenase 1 gene transfer prevents CD95\/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway","volume":"13","author":"Ke","year":"2002","journal-title":"Hum Gene Ther"},{"key":"10.1124\/pr.57.4.3_REF204","series-title":"The History of Cell Respiration and Cytochrome","first-page":"252","article-title":"Chapter 11: inhibition of cell respiration by carbon monoxide","author":"Keilin","year":"1966"},{"key":"10.1124\/pr.57.4.3_REF205","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1073\/pnas.86.1.99","article-title":"Heme oxygenase is the major 32 kDa stress protein induced in human skin fibroblasts of UVA radiation, hydrogen peroxide and sodium arsenite","volume":"86","author":"Keyse","year":"1989","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF206","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1073\/pnas.92.7.2568","article-title":"Basis of guanylate cyclase activation by carbon monoxide","volume":"92","author":"Kharitonov","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF207","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1067\/mva.2000.105006","article-title":"Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42\/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate","volume":"31","author":"Kibbe","year":"2000","journal-title":"J Vasc Surg"},{"key":"10.1124\/pr.57.4.3_REF208","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1210\/endo.141.6.7500","article-title":"Nitric oxide and carbon monoxide have a stimulatory role in the hypothalamic-pituitary-adrenal response to physico-emotional stressors in rats","volume":"141","author":"Kim","year":"2000","journal-title":"Endocrinology"},{"key":"10.1124\/pr.57.4.3_REF209","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/(SICI)1099-1263(199609)16:5<437::AID-JAT371>3.0.CO;2-2","article-title":"Effect of a single administration of benzene, toluene or m-xylene on carboxyhaemoglobin elevation and metabolism of dichloromethane in rats","volume":"16","author":"Kim","year":"1996","journal-title":"J Appl Toxicol"},{"key":"10.1124\/pr.57.4.3_REF210","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF00297197","article-title":"Lack of effect of carbon monoxide inhibitor on relaxation induced by electrical field stimulation in corpus cavernosum","volume":"22","author":"Kim","year":"1994","journal-title":"Urol Res"},{"key":"10.1124\/pr.57.4.3_REF211","doi-asserted-by":"crossref","first-page":"9125","DOI":"10.1074\/jbc.M209939200","article-title":"Bach1 functions as a hypoxiainducible repressor for the heme oxygenase-1 gene in human cells","volume":"278","author":"Kitamuro","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF212","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1089\/152308602753666334","article-title":"Cerebrovascular effects of carbon monoxide","volume":"4","author":"Koehler","year":"2002","journal-title":"Antioxid Redox Signal"},{"key":"10.1124\/pr.57.4.3_REF213","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0006-2952(02)01056-0","article-title":"Biliverdin IX is an endogenous inhibitor of soluble guanylyl cyclase","volume":"64","author":"Koglin","year":"2002","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF214","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1159\/000054425","volume":"69","author":"Kohsaka","year":"1999","journal-title":"Neuroendocrinology"},{"key":"10.1124\/pr.57.4.3_REF215","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0031-6865(97)00044-7","article-title":"Alterations of the vascular and the myocardial guanylate cyclase\/cGMP-system induced by longterm hypertension in rats","volume":"73","author":"Kojda","year":"1998","journal-title":"Pharm Acta Helv"},{"key":"10.1124\/pr.57.4.3_REF216","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0165-5728(98)00028-9","article-title":"Endotoxin stimulates an endogenous pathway regulating corticotropin-releasing hormone and vasopressin release involving the generation of nitric oxide and carbon monoxide","volume":"86","author":"Kostoglou-Athanassiou","year":"1998","journal-title":"J Neuroimmunol"},{"key":"10.1124\/pr.57.4.3_REF217","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0169-328X(96)00137-4","article-title":"Oxytocin release is inhibited by the generation of carbon monoxide from the rat hypothalamus-further evidence for carbon monoxide as a neuromodulator","volume":"42","author":"Kostoglou-Athanassiou","year":"1996","journal-title":"Mol Brain Res"},{"key":"10.1124\/pr.57.4.3_REF218","doi-asserted-by":"crossref","first-page":"R1087","DOI":"10.1152\/ajpregu.1999.276.4.R1087","article-title":"Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels","volume":"276","author":"Kozma","year":"1999","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"Suppl 1","key":"10.1124\/pr.57.4.3_REF219","first-page":"61","article-title":"The role of heme oxygenase (HO) in the regulation of somatic growth factors in pregnancy (Abstract 243)","volume":"103","author":"Kreiser","year":"2000","journal-title":"Acta Hematologica"},{"key":"10.1124\/pr.57.4.3_REF220","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1006\/bbrc.1994.1436","article-title":"Light-activated release of nitric oxide from vascular smooth muscle of normotensive and hypertensive rats","volume":"200","author":"Kubaszewski","year":"1993","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF221","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/0006-2952(78)90143-0","article-title":"Metabolism of dihalomethanes to carbon monoxide\u2014III. Studies on the mechanism of the reaction","volume":"27","author":"Kubic","year":"1978","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF222","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1006\/geno.1994.1213","article-title":"Chromosomal localization of the human heme oxygenase genes (HMOX2) heme oxygenase-1 (HMOX1) maps to chromosome 22q12 and heme oxygenase-2: maps to chromosome 16p13.3","volume":"20","author":"Kutty","year":"1994","journal-title":"Genomics"},{"key":"10.1124\/pr.57.4.3_REF223","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/0003-9861(89)90569-9","article-title":"Selective induction of heme oxygenase-1 isozyme in rat testis by human chorionic gonadotropin","volume":"268","author":"Kutty","year":"1989","journal-title":"Arch Biochem Biophys"},{"key":"10.1124\/pr.57.4.3_REF224","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/jcp.1041590221","article-title":"Increased expression of heme oxygenase-1 in human retinal pigment epithelial cells by transforming growth factor-beta","volume":"159","author":"Kutty","year":"1994","journal-title":"J Cell Physiol"},{"key":"10.1124\/pr.57.4.3_REF225","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1292\/jvms.63.389","article-title":"Mechanism of carbon monoxide-induced relaxation in the guinea pig ileal smooth muscle","volume":"63","author":"Kwon","year":"2001","journal-title":"J Vet Med Sci"},{"key":"10.1124\/pr.57.4.3_REF226","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1006\/jmcc.2002.2094","article-title":"Expression of heme oxygenase-1 in response to myocardial infarction in rats","volume":"34","author":"Lakkisto","year":"2002","journal-title":"J Mol Cell Cardiol"},{"key":"10.1124\/pr.57.4.3_REF227","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1210\/endo.137.2.8593832","article-title":"Regulation of gonadotropin releasing hormone secretion by heme molecules: a regulatory role for carbon monoxide?","volume":"137","author":"Lamar","year":"1996","journal-title":"Endocrinology"},{"key":"10.1124\/pr.57.4.3_REF228","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1172\/JCI106311","article-title":"Catabolism of heme in vivo: comparison of the simultaneous production of bilirubin and carbon monoxide","volume":"49","author":"Landaw","year":"1970","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF229","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1093\/carcin\/13.2.227","article-title":"Endogenous glutathione levels modulate both constitutive and UVA radiation\/hydrogen peroxide inducible expression of the human heme oxygenase gene","volume":"13","author":"Lautier","year":"1992","journal-title":"Carcinogenesis"},{"key":"10.1124\/pr.57.4.3_REF230","doi-asserted-by":"crossref","first-page":"5987","DOI":"10.1073\/pnas.91.13.5987","article-title":"Identification of binding sites for transcription factors NF-\u03baB and AP-2 in the promoter region of the human heme oxygenase 1 gene","volume":"91","author":"Lavrovsky","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF231","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2337\/diabetes.51.2.413","article-title":"Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to \u03b2-cell survival during chronic hyperglycemia","volume":"51","author":"Laybutt","year":"2002","journal-title":"Diabetes"},{"key":"10.1124\/pr.57.4.3_REF232","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/BF02975174","article-title":"Effects of heme oxygenase system on the cyclooxygenase in the primary cultured hypothalamic cells","volume":"24","author":"Lee","year":"2001","journal-title":"Arch Pharm Res (NY)"},{"key":"10.1124\/pr.57.4.3_REF233","doi-asserted-by":"crossref","first-page":"10393","DOI":"10.1073\/pnas.93.19.10393","article-title":"Overexpression of heme oygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia","volume":"93","author":"Lee","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF234","doi-asserted-by":"crossref","first-page":"5375","DOI":"10.1074\/jbc.272.9.5375","article-title":"Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia","volume":"272","author":"Lee","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF235","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nm0302-240","article-title":"Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice","volume":"8","author":"Lee","year":"2002","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF236","doi-asserted-by":"crossref","first-page":"H74","DOI":"10.1152\/ajpheart.01081.2002","article-title":"Mechanism of glutamate stimulation of CO production in cerebral microvessels","volume":"285","author":"Leffler","year":"2003","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF236a","doi-asserted-by":"crossref","first-page":"H1490","DOI":"10.1152\/ajpheart.2001.280.4.H1490","article-title":"Contributions of prostacyclin and nitric oxide to carbon monoxide-induced cerebrovascular dilation in piglets","volume":"280","author":"Leffler","year":"2001","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF238","doi-asserted-by":"crossref","first-page":"H1641","DOI":"10.1152\/ajpheart.1999.276.5.H1641","article-title":"Carbon monoxide and cerebral microvascular tone in newborn pigs","volume":"276","author":"Leffler","year":"1999","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF239","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1152\/jn.1995.74.4.1498","article-title":"Regulation of cyclic nucleotidegated channels and membrane excitability in olfactory receptor cells by carbon monoxide","volume":"74","author":"Leinders-Zufall","year":"1995","journal-title":"J Neurophysiol"},{"key":"10.1124\/pr.57.4.3_REF240","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1172\/JCI114686","article-title":"Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats","volume":"86","author":"Levere","year":"1990","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF241","doi-asserted-by":"crossref","first-page":"F914","DOI":"10.1152\/ajprenal.00073.2004","article-title":"Angiotensin II induces carbon monoxide production in the perfused kidney: relationship to protein kinase C activation","volume":"287","author":"Li","year":"2004","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/pr.57.4.3_REF242","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.bbrc.2004.01.090","article-title":"Immunocytochemical localization and expression of heme oxygenase-1 in primary astroglial cell cultures during differentiation: effect of glutamate","volume":"315","author":"Li Volti","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF243","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/S0006-291X(02)02054-5","article-title":"Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression","volume":"296","author":"Li Volti","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF244","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0169-328X(99)00254-5","article-title":"Chronic morphine exposure and the expression of heme oxygenase type 2","volume":"75","author":"Li","year":"2000","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1124\/pr.57.4.3_REF245","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1097\/00000539-200003000-00031","article-title":"The role of heme oxygenase in neuropathic and incisional pain","volume":"90","author":"Li","year":"2000","journal-title":"Anesth Analg"},{"key":"10.1124\/pr.57.4.3_REF246","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1054\/jpai.2003.18","article-title":"Heme oxygenase type 2 participates in the development of chronic inflammatory and neuropathic pain","volume":"4","author":"Li","year":"2003","journal-title":"J Pain"},{"key":"10.1124\/pr.57.4.3_REF247","doi-asserted-by":"crossref","first-page":"F728","DOI":"10.1152\/ajprenal.2000.279.4.F728","article-title":"Mechanisms underlying induction of heme oxygenase-1 by nitric oxide in renal tubular epithelial cells","volume":"279","author":"Liang","year":"2000","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/pr.57.4.3_REF248","doi-asserted-by":"crossref","first-page":"G7","DOI":"10.1152\/ajpgi.00205.2004","article-title":"Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanism","volume":"288","author":"Lim","year":"2005","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1124\/pr.57.4.3_REF249","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3109\/01480548809018109","article-title":"Vasodilating effects of carbon monoxide","volume":"11","author":"Lin","year":"1988","journal-title":"Drug Chem Toxicol"},{"key":"10.1124\/pr.57.4.3_REF250","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1152\/jn.1993.70.6.2673","article-title":"Protoporphyrins modulate voltagegated Ca current in AtT-20 pituitary cells","volume":"70","author":"Linden","year":"1993","journal-title":"J Neurophysiol"},{"key":"10.1124\/pr.57.4.3_REF251","doi-asserted-by":"crossref","first-page":"G68","DOI":"10.1152\/ajpgi.2001.280.1.G68","article-title":"Role of heme oxygenase-carbon monoxide pathway in pathogenesis of cirrhotic cardiomyopathy in the rat","volume":"280","author":"Liu","year":"2001","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1124\/pr.57.4.3_REF252","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0378-1119(99)00439-4","article-title":"Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression","volume":"241","author":"Liu","year":"2000","journal-title":"Gene"},{"key":"10.1124\/pr.57.4.3_REF253","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S0008-6363(02)00410-8","article-title":"Carbon monoxide inhibits apoptosis in vascular smooth muscle cells","volume":"55","author":"Liu","year":"2002","journal-title":"Cardiovasc Res"},{"key":"10.1124\/pr.57.4.3_REF254","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1161\/hc0102.101369","article-title":"Adenovirus-mediated heme oxygenase-1 gene expression stimulates apoptosis in vascular smooth muscle cells","volume":"105","author":"Liu","year":"2002","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF255","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1074\/jbc.M410413200","article-title":"Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle: role in cell survival","volume":"280","author":"Liu","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF256","doi-asserted-by":"crossref","first-page":"15257","DOI":"10.1074\/jbc.273.24.15257","article-title":"Carbon monoxide and nitric oxide suppress the hypoxic induction of vascular endothelial growth factor gene via the 5\u2032 enhancer","volume":"273","author":"Liu","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF257","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1097\/00001756-200107030-00016","article-title":"Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis","volume":"12","author":"Liu","year":"2001","journal-title":"Neuroreport"},{"key":"10.1124\/pr.57.4.3_REF258","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0167-4889(94)90067-1","article-title":"Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage","volume":"1223","author":"Llesuy","year":"1994","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF259","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1600-0773.1999.tb00091.x","article-title":"Chronic carbon monoxide exposure in vivo induces myocardial endothelin-1 expression and hypertrophy in rat","volume":"85","author":"Loennechen","year":"1999","journal-title":"Pharmacol Toxicol"},{"key":"10.1124\/pr.57.4.3_REF260","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1006\/taap.2001.9300","article-title":"Chronic exposure to carbon monoxide and nicotine: endothelin ET(A) receptor antagonism attenuates carbon monoxide-induced myocardial hypertrophy in rat","volume":"178","author":"Loennechen","year":"2002","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF261","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/S0002-9378(99)70336-4","article-title":"Effect of nitric oxide and carbon monoxide on uterine contractility during human and rat pregnancy","volume":"181","author":"Longo","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1124\/pr.57.4.3_REF262","doi-asserted-by":"crossref","first-page":"12424","DOI":"10.1021\/bi001257c","article-title":"Resonance Raman studies indicate a unique heme active site in prostaglandin H synthase","volume":"39","author":"Lou","year":"2000","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF263","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0378-1119(97)00623-9","article-title":"Molecular cloning, characterization and expression of the chicken heme oxygenase-1 gene in transfected primary cultures of chick embryo liver cells","volume":"207","author":"Lu","year":"1998","journal-title":"Gene"},{"key":"10.1124\/pr.57.4.3_REF264","doi-asserted-by":"crossref","first-page":"E1055","DOI":"10.1152\/ajpendo.00498.2002","article-title":"Carbon monoxide stimulates insulin release and propagates Ca2+ signals between pancreatic \u03b2-cells","volume":"285","author":"Lundquist","year":"2003","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1124\/pr.57.4.3_REF265","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0922-4106(94)90149-X","article-title":"Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo","volume":"267","author":"Luo","year":"1994","journal-title":"Eur J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF266","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1152\/ajplegacy.1969.217.2.354","article-title":"Effects of metabolism and distribution of carbon monoxide on blood and body stores","volume":"217","author":"Luomanmaki","year":"1969","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF267","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1096\/fasebj.14.1.208","article-title":"Hemeoxygenase expression in human placenta and placental bed implies a role in regulation of trophoblast invasion and placental function","volume":"14","author":"Lyall","year":"2000","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF268","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1681\/ASN.V1091997","article-title":"In vitro and in vivo immunomodulatory effects of RDP1258, a novel synthetic peptide","volume":"10","author":"Magee","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"10.1124\/pr.57.4.3_REF269","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1096\/fasebj.2.10.3290025","article-title":"Heme oxygenase: function, multiplicity, regulatory mechanisms and clinical applications","volume":"2","author":"Maines","year":"1988","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF270","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1146\/annurev.pharmtox.37.1.517","article-title":"The heme oxygenase system: a regulator of second messenger gases","volume":"37","author":"Maines","year":"1997","journal-title":"Annu Rev Pharmacol Toxicol"},{"key":"10.1124\/pr.57.4.3_REF271","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1095\/biolreprod54.5.1070","article-title":"Stress response of the rat testis: in situ hybridization and immunohistochemical analysis of heme oxygenase-1 (HSP32) induction by hyperthermia","volume":"54","author":"Maines","year":"1996","journal-title":"Biol Reproduct"},{"key":"10.1124\/pr.57.4.3_REF272","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1073\/pnas.71.11.4293","article-title":"Cobalt induction of hepatic heme oxygenase: with evidence that Cyt P450 is not essential for this enzyme activity","volume":"71","author":"Maines","year":"1974","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF273","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0003-9861(83)90278-3","article-title":"Differential response of testicular and ovarian heme oxygenase activity to metal ions","volume":"226","author":"Maines","year":"1983","journal-title":"Arch Biochem Biophys"},{"key":"10.1124\/pr.57.4.3_REF274","first-page":"457","article-title":"Induction of kidney heme oxygenase-1 (HSP32) mRNA and protein byischemia\/reperfusion: possible role of heme as both promotor of tissue damage and regulator of HSP32","volume":"264","author":"Maines","year":"1993","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/pr.57.4.3_REF275","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0021-9258(17)42488-4","article-title":"Characterization of two constitutive forms of rat liver microsomal heme oxygenase: Only one molecular species of the enzyme is inducible","volume":"261","author":"Maines","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF276","first-page":"433","article-title":"Significance of heme oxygenase in prolactin-mediated cell proliferation and angiogenesis in human endothelial cells","volume":"10","author":"Malaguarnera","year":"2002","journal-title":"Int J Mol Med"},{"key":"10.1124\/pr.57.4.3_REF277","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0169-328X(97)00197-6","article-title":"Activation of heme oxygenase and consequent carbon monoxide formation inhibits the release of arginine vasopressin from rat hypothalamic explants. Molecular linkage between heme catabolism and neuroendocrine function","volume":"50","author":"Mancuso","year":"1997","journal-title":"Mol Brain Res"},{"key":"10.1124\/pr.57.4.3_REF278","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1159\/000097340","article-title":"The role of carbon monoxide in the regulation of neuroendocrine function","volume":"4","author":"Mancuso","year":"1997","journal-title":"Neuroimmunomodulation"},{"key":"10.1124\/pr.57.4.3_REF279","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/BF01952415","article-title":"Inhibition of platelet ADP and serotonin release by carbon monoxide and in cigarette smokers","volume":"40","author":"Mansouri","year":"1984","journal-title":"Experientia"},{"key":"10.1124\/pr.57.4.3_REF280","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0165-6147(91)90544-3","article-title":"Does carbon monoxide have a physiological function?","volume":"12","author":"Marks","year":"1991","journal-title":"Trends Pharmacol Sci"},{"key":"10.1124\/pr.57.4.3_REF281","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1096\/fj.00.011rev","article-title":"Nitrosation and oxidation in the regulation of gene expression","volume":"14","author":"Marshall","year":"2000","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF282","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF01851008","article-title":"[Acute effects of low carbon monoxide concentrations on blood rheology, platelet fuction and the arterial wall in the minipig (author\u2019s transl)]","volume":"178","author":"Marshall","year":"1981","journal-title":"Res Exp Med (Berl)"},{"key":"10.1124\/pr.57.4.3_REF283","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0006-8993(95)01511-6","article-title":"Heme-oxygenase-1 induction in glia throughout rat brain following experimental subarachnoid hemorrhage","volume":"713","author":"Matz","year":"1996","journal-title":"Brain Res"},{"issue":"9 Suppl","key":"10.1124\/pr.57.4.3_REF284","first-page":"II398","article-title":"Nitric oxide\/carbon monoxide. A molecular switch for myocardial preservation during ischemia","volume":"94","author":"Maulik","year":"1996","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF285","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1006\/exnr.2000.7520","article-title":"Sustained induction of heme oxygenase-1 in the traumatized spinal cord","volume":"166","author":"Mautes","year":"2000","journal-title":"Exp Neurol"},{"key":"10.1124\/pr.57.4.3_REF286","doi-asserted-by":"crossref","first-page":"12568","DOI":"10.1074\/jbc.272.19.12568","article-title":"Heme oxygenase-2 is a hemoprotein and binds heme through heme regulatory motifs that are not involved in heme catalysis","volume":"272","author":"McCoubrey","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF287","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/j.1432-1033.1997.00725.x","article-title":"Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3","volume":"247","author":"McCoubrey","year":"1997","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF288","doi-asserted-by":"crossref","first-page":"132","DOI":"10.3181\/00379727-177-41922","article-title":"Response of rat coronary circulation to carbon monoxide and nitrogen hypoxia","volume":"177","author":"McGrath","year":"1984","journal-title":"Proc Soc Exp Biol Med"},{"key":"10.1124\/pr.57.4.3_REF289","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1053\/plac.2000.0574","article-title":"Heme oxygenase activity in term human placenta","volume":"21","author":"McLaughlin","year":"2000","journal-title":"Placenta"},{"key":"10.1124\/pr.57.4.3_REF290","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1038\/sj.bjp.0703499","article-title":"Selective modifiers of glutathione biosynthesis and \u2018repriming\u2019 of vascular smooth muscle photorelaxation","volume":"130","author":"Megson","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF291","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1152\/jappl.1996.81.3.1078","article-title":"Effects of carbon monoxide on the brain may be mediated by nitric oxide","volume":"81","author":"Meilin","year":"1996","journal-title":"J Appl Physiol"},{"key":"10.1124\/pr.57.4.3_REF292","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1161\/hc0502.103363","article-title":"Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene","volume":"105","author":"Melo","year":"2002","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF293","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1095\/biolreprod63.2.651","article-title":"Generation of cyclic guanosine monophosphate by heme oxygenases in the human testis\u2013a regulatory role for carbon monoxide in Sertoli cells?","volume":"63","author":"Middendorff","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1124\/pr.57.4.3_REF294","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1172\/JCI109507","article-title":"Role of cytochrome P-450 in alveolar hypoxic pulmonary vasoconstriction in dogs","volume":"64","author":"Miller","year":"1979","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF295","first-page":"137","article-title":"A new approach to the treatment of sickle cell anemia","volume":"12","author":"Milosz","year":"1975","journal-title":"Res Commun Chem Pathol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF296","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/oxfordjournals.jbchem.a129450","article-title":"Biological CO evolution. Carbon monoxide evolution during auto- and enzymatic oxidation of phenols","volume":"69","author":"Miyahara","year":"1971","journal-title":"J Biochem (Tokyo)"},{"key":"10.1124\/pr.57.4.3_REF297","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S0006-8993(98)00607-6","article-title":"High pCO does not alter pHi, but raises [Ca2+]i in cultured rat carotid body glomus cells in the absence and presence of CdCl2","volume":"803","author":"Mokashi","year":"1998","journal-title":"Brain Res"},{"key":"10.1124\/pr.57.4.3_REF298","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1152\/jappl.1973.35.4.505","article-title":"Oxygenation during inhibition of drug metabolism by carbon monoxide or hypoxic hypoxia","volume":"35","author":"Montgomery","year":"1973","journal-title":"J Appl Physiol"},{"key":"10.1124\/pr.57.4.3_REF299","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S0167-4838(01)00192-3","article-title":"Enzymatic properties of human hemalbumin","volume":"1547","author":"Monzani","year":"2001","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF300","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1016\/S0021-9258(17)33557-3","article-title":"Cooperativity in the dissociation of nitric oxide from hemoglobin","volume":"251","author":"Moore","year":"1976","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF301","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.1172\/JCI118334","article-title":"Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide","volume":"96","author":"Morita","year":"1995","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF302","doi-asserted-by":"crossref","first-page":"32804","DOI":"10.1074\/jbc.272.52.32804","article-title":"Carbon monoxide controls the proliferation of hypoxic vascular smooth muscle cells","volume":"272","author":"Morita","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF303","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1046\/j.1523-1755.1998.00798.x","article-title":"Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease","volume":"53","author":"Mosley","year":"1998","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF304","doi-asserted-by":"crossref","first-page":"E17","DOI":"10.1161\/hh0202.104530","article-title":"Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities","volume":"90","author":"Motterlini","year":"2002","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF305","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S0891-5849(00)00294-X","article-title":"Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress","volume":"28","author":"Motterlini","year":"2000","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/pr.57.4.3_REF306","series-title":"Carbon Monoxide and Cardiovascular Functions","first-page":"249","article-title":"Studies on the development of carbon monoxide-releasing molecules: potential applications for the treatment of cardiovascular dysfunction","author":"Motterlini","year":"2002"},{"key":"10.1124\/pr.57.4.3_REF307","doi-asserted-by":"crossref","first-page":"H107","DOI":"10.1152\/ajpheart.1996.270.1.H107","article-title":"NOmediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium","volume":"270","author":"Motterlini","year":"1996","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF308","doi-asserted-by":"crossref","first-page":"7181","DOI":"10.1021\/bi952167o","article-title":"Hemoblogin oxidation products extract phospholipids from the membrane of human erythrocytes","volume":"35","author":"Moxness","year":"1996","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF309","doi-asserted-by":"crossref","first-page":"6795","DOI":"10.1016\/S0021-9258(18)48315-9","article-title":"Nucleotide sequence and organization of the rat heme oxygenase gene","volume":"262","author":"Muller","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF310","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/0076-6879(88)63049-7","article-title":"Hemopexin","volume":"163","author":"Muller-Eberhard","year":"1988","journal-title":"Meth Enzymol"},{"key":"10.1124\/pr.57.4.3_REF311","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1432-1033.1996.00471.x","article-title":"cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene","volume":"235","author":"Muraosa","year":"1996","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF312","doi-asserted-by":"crossref","first-page":"H220","DOI":"10.1152\/ajpheart.01131.2002","article-title":"Heme oxygenase-mediated vasodilation involves vascular smooth muscle cell hyperpolarization","volume":"285","author":"Naik","year":"2003","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"Suppl 1","key":"10.1124\/pr.57.4.3_REF313","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1365-2036.2004.01992.x","article-title":"Heme oxygenase-1: a new therapeutic target for inflammatory bowel disease","volume":"20","author":"Naito","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1124\/pr.57.4.3_REF314","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1006\/bbrc.2000.2683","article-title":"Repression of heme oxygenase-1 by hypoxia in vascular endothelial cells","volume":"271","author":"Nakayama","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF315","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1172\/JCI115847","article-title":"Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat","volume":"90","author":"Nath","year":"1992","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF316","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1046\/j.1523-1755.1998.00731.x","article-title":"Intracellular targets in heme protein-induced renal injury","volume":"53","author":"Nath","year":"1998","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF317","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0002-9440(10)64037-0","article-title":"Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease","volume":"158","author":"Nath","year":"2001","journal-title":"Am J Pathol"},{"key":"10.1124\/pr.57.4.3_REF318","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0002-9440(10)65024-9","article-title":"The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo","volume":"156","author":"Nath","year":"2000","journal-title":"Am J Pathol"},{"key":"10.1124\/pr.57.4.3_REF319","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/0896-6273(95)90222-8","article-title":"The cellular NaC pump as a site of action for carbon monoxide and glutamate: a mechanism for long-term modulation of cellular activity","volume":"14","author":"Nathanson","year":"1995","journal-title":"Neuron"},{"key":"10.1124\/pr.57.4.3_REF320","first-page":"317","article-title":"Evidence for a functional link between the heme oxygenase-carbon monoxide pathway and corticotropin-releasing hormone release from primary cultures of human trophoblast cells","volume":"86","author":"Navarra","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1124\/pr.57.4.3_REF321","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1097\/00004872-200406000-00002","article-title":"Carbon monoxide and hypertension","volume":"22","author":"Ndisang","year":"2004","journal-title":"J Hypertension"},{"key":"10.1124\/pr.57.4.3_REF322","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1161\/01.HYP.0000028488.71068.16","article-title":"Mechanisms underlying selective regulation of blood pressure by heme oxygenase-1 in hypertension","volume":"40","author":"Ndisang","year":"2002","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF323","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1097\/00004872-200306000-00011","article-title":"Age-related alterations in soluble guanylyl cyclase and cGMP pathway in spontaneously hypertensive rats","volume":"21","author":"Ndisang","year":"2003","journal-title":"J Hypertens"},{"key":"10.1124\/pr.57.4.3_REF324","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1177\/15353702-0322805-27","article-title":"Alterations in heme oxygenase\/carbon monoxide system in pulmonary artery in hypertension","volume":"228","author":"Ndisang","year":"2003","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1124\/pr.57.4.3_REF325","doi-asserted-by":"crossref","first-page":"3893","DOI":"10.1182\/blood-2002-08-2608","article-title":"Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats","volume":"101","author":"Ndisang","year":"2003","journal-title":"Blood"},{"key":"10.1124\/pr.57.4.3_REF326","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/jop.1995.11.455","article-title":"Modulation of corneal heme oxygenase expression by oxidative stress agents","volume":"11","author":"Neil","year":"1995","journal-title":"J Ocul Pharmacol Ther"},{"key":"10.1124\/pr.57.4.3_REF327","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0169-328X(95)00315-J","article-title":"Heme oxygenase-1 (HO-1) protein induction in rat brain following focal ischemia","volume":"37","author":"Nimura","year":"1996","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1124\/pr.57.4.3_REF328","series-title":"Structure and Function of Cytochromes","first-page":"658","author":"Nishibayashi","year":"1968"},{"key":"10.1124\/pr.57.4.3_REF329","doi-asserted-by":"crossref","first-page":"H2296","DOI":"10.1152\/ajpheart.00671.2003","article-title":"In vivo role of heme oxygenase in ischemic coronary vasodilation","volume":"286","author":"Nishikawa","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF330","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1089\/152308603768295195","article-title":"Carbon monoxide stimulates mrp2-dependent excretion of bilirubin-IXa into bile in the perfused rat liver","volume":"5","author":"Norimizu","year":"2003","journal-title":"Antioxid Redox Signal"},{"key":"10.1124\/pr.57.4.3_REF331","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1476-5381.1996.tb15415.x","article-title":"Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter","volume":"118","author":"Ny","year":"1996","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF332","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1476-5381.1995.tb16337.x","article-title":"Inhibition by zinc protoporphyrin-IX of receptor-mediated relaxation of the rat aorta in a manner distinct from inhibition of haem oxygenase","volume":"115","author":"Ny","year":"1995","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF333","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0143-4004(98)91044-X","article-title":"Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation","volume":"19","author":"Odrcich","year":"1998","journal-title":"Placenta"},{"key":"10.1124\/pr.57.4.3_REF334","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1093\/emboj\/20.11.2835","article-title":"Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1","volume":"20","author":"Ogawa","year":"2001","journal-title":"EMBO (Eur Mol Biol Organ) J"},{"key":"10.1124\/pr.57.4.3_REF335","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0272-6386(00)70256-3","article-title":"Tubular injury as a cardinal pathologic feature in human heme oxygenase-1 deficiency","volume":"35","author":"Ohta","year":"2000","journal-title":"Am J Kidney Dis"},{"key":"10.1124\/pr.57.4.3_REF336","doi-asserted-by":"crossref","first-page":"5074","DOI":"10.1182\/blood.V87.12.5074.bloodjournal87125074","article-title":"Regulation of human heme oxygenase-1 gene expression under thermal stress","volume":"87","author":"Okinaga","year":"1996","journal-title":"Blood"},{"key":"10.1124\/pr.57.4.3_REF337","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1046\/j.1442-200X.2001.01412.x","article-title":"End-tidal carbon monoxide is predictive for neonatal non-hemolytic hyperbilirubinemia","volume":"43","author":"Okuyama","year":"2001","journal-title":"Pediatr Int"},{"key":"10.1124\/pr.57.4.3_REF338","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1021\/ar960207q","article-title":"Heme oxygenase mechanism: evidence for an electrophilic, ferric peroxide species","volume":"31","author":"Ortiz de Montellano","year":"1998","journal-title":"Acc Chem Res"},{"key":"10.1124\/pr.57.4.3_REF339","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/74680","article-title":"Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway","volume":"6","author":"Otterbein","year":"2000","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF340","doi-asserted-by":"crossref","first-page":"L1029","DOI":"10.1152\/ajplung.2000.279.6.L1029","article-title":"Heme oxygenase: colors of defense against cellular stress","volume":"279","author":"Otterbein","year":"2000","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1124\/pr.57.4.3_REF341","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1172\/JCI5342","article-title":"Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury","volume":"103","author":"Otterbein","year":"1999","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF342","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/978-1-4615-5891-0_52","article-title":"Carbon monoxide and carotid body chemoreception","volume":"410","author":"Overholt","year":"1996","journal-title":"Adv Exp Med Biol"},{"key":"10.1124\/pr.57.4.3_REF343","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1172\/JCI0213190","article-title":"Leydig cell-derived heme oxygenase-1 regulates apoptosis of premeiotic germ cells in response to stress","volume":"109","author":"Ozawa","year":"2002","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF344","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.4049\/jimmunol.172.8.4744","article-title":"Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production","volume":"172","author":"Pae","year":"2004","journal-title":"J Immunol"},{"key":"10.1124\/pr.57.4.3_REF345","first-page":"L212","article-title":"Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1","volume":"274","author":"Palmer","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF346","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1111\/j.1471-4159.1999.721187.x","article-title":"Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice","volume":"72","author":"Panahian","year":"1999","journal-title":"J Neurochem"},{"key":"10.1124\/pr.57.4.3_REF347","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0300-483X(91)90064-8","article-title":"Influence of aromatic hydrocarbons on the metabolism of dichloromethane to carbon monoxide in rats","volume":"68","author":"Pankow","year":"1991","journal-title":"Toxicology"},{"key":"10.1124\/pr.57.4.3_REF348","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1016\/S0024-3205(98)00174-X","article-title":"Differential regulation of hepatic arterial and portal venous vascular resistance by nitric oxide and carbon monoxide in rats","volume":"62","author":"Pannen","year":"1998","journal-title":"Life Sci"},{"key":"10.1124\/pr.57.4.3_REF349","doi-asserted-by":"crossref","first-page":"9802","DOI":"10.1074\/jbc.272.15.9802","article-title":"Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress","volume":"272","author":"Pantopulos","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF350","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1161\/01.HYP.26.4.696","article-title":"Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA and protein levels by cAMP-elevating agents","volume":"26","author":"Papapetropoulos","year":"1995","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF351","doi-asserted-by":"crossref","first-page":"C1954","DOI":"10.1152\/ajpcell.2001.281.6.C1954","article-title":"Cerebral vascular endothelial heme oxygenase: expression, localization and activation by glutamate","volume":"281","author":"Parfenova","year":"2001","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1124\/pr.57.4.3_REF352","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0006-8993(94)90097-3","article-title":"Carbon monoxide modulates secretion of corticotropin-releasing factor from rat hypothalamic cell cultures","volume":"646","author":"Parkes","year":"1994","journal-title":"Brain Res"},{"key":"10.1124\/pr.57.4.3_REF353","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0300-483X(93)90179-V","article-title":"Carbon monoxide-induced cardiac hypertrophy is not reduced by alpha- or beta-blockade in the rat","volume":"80","author":"Penney","year":"1993","journal-title":"Toxicology"},{"key":"10.1124\/pr.57.4.3_REF354","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1152\/jappl.1992.73.5.1713","article-title":"Heart and lung alterations in neonatal rats exposed to CO or high altitude","volume":"73","author":"Penney","year":"1992","journal-title":"J Appl Physiol"},{"key":"10.1124\/pr.57.4.3_REF355","doi-asserted-by":"crossref","first-page":"L312","DOI":"10.1152\/ajplung.2000.278.2.L312","article-title":"Heme oxygenase-1 inhibits TNF-alpha-induced apoptosis in cultured fibroblasts","volume":"278","author":"Petrache","year":"2000","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1124\/pr.57.4.3_REF356","doi-asserted-by":"crossref","first-page":"4443","DOI":"10.1182\/blood.V99.12.4443","article-title":"Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth","volume":"99","author":"Peyton","year":"2002","journal-title":"Blood"},{"key":"10.1124\/pr.57.4.3_REF357","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1089\/152308602753666316","article-title":"Biological chemistry of carbon monoxide","volume":"4","author":"Piantadosi","year":"2002","journal-title":"Antioxid Redox Signal"},{"key":"10.1124\/pr.57.4.3_REF358","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0891-5849(95)00168-W","article-title":"Hydroxyl radical production in the brain after CO hypoxia in rats","volume":"18","author":"Piantadosi","year":"1995","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/pr.57.4.3_REF359","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1523\/JNEUROSCI.16-04-01389.1996","article-title":"Nitric oxide and carbon monoxide activate locus coeruleus neurons through a cGMP-dependent protein kinase: involvement of a nonselective cationic channel","volume":"16","author":"Pineda","year":"1996","journal-title":"J Neurosci"},{"key":"10.1124\/pr.57.4.3_REF360","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1038\/3947","article-title":"Heme oxygenase: protective gene or Trojan horse","volume":"4","author":"Platt","year":"1998","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF361","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1677\/joe.0.1800113","article-title":"Adrenocorticotropin induces heme oxygenase-1 expression in adrenal cells","volume":"180","author":"Pomeraniec","year":"2004","journal-title":"J Endocrinol"},{"key":"10.1124\/pr.57.4.3_REF362","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0002-9629(15)40628-7","article-title":"Cell biology of heme","volume":"318","author":"Ponka","year":"1999","journal-title":"Am J Med Sci"},{"key":"10.1124\/pr.57.4.3_REF363","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/0896-6273(95)90177-9","article-title":"Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice","volume":"15","author":"Poss","year":"1995","journal-title":"Neuron"},{"key":"10.1124\/pr.57.4.3_REF364","doi-asserted-by":"crossref","first-page":"10919","DOI":"10.1073\/pnas.94.20.10919","article-title":"Heme oxygenase 1 is required for mammalian iron reutilization","volume":"94","author":"Poss","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF365","doi-asserted-by":"crossref","first-page":"10925","DOI":"10.1073\/pnas.94.20.10925","article-title":"Reduced stress defense in heme oxygenase 1-deficient cells","volume":"94","author":"Poss","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF366","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1210\/endo.135.6.7988414","article-title":"Carbon monoxide as a novel neuroendocrine modulator: inhibition of stimulated corticotropin-releasing hormone release from acute rat hypothalamic explants","volume":"135","author":"Pozzoli","year":"1994","journal-title":"Endocrinology"},{"key":"10.1124\/pr.57.4.3_REF367","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0034-5687(99)00019-5","article-title":"NO and CO as second messengers in oxygen sensing in the carotid body","volume":"115","author":"Prabhakar","year":"1999","journal-title":"Respir Physiol"},{"key":"10.1124\/pr.57.4.3_REF368","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1046\/j.1471-4159.1995.65031399.x","article-title":"Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer\u2019s disease","volume":"65","author":"Premkumar","year":"1995","journal-title":"J Neurochem"},{"key":"10.1124\/pr.57.4.3_REF369","doi-asserted-by":"crossref","first-page":"12203","DOI":"10.1073\/pnas.211399398","article-title":"Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs","volume":"98","author":"Quan","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF370","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1080\/10409230490496577","article-title":"Life with carbon monoxide","volume":"39","author":"Ragsdale","year":"2004","journal-title":"Crit Rev Biochem Mol Biol"},{"key":"10.1124\/pr.57.4.3_REF371","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0167-4781(96)00183-2","article-title":"Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element","volume":"1351","author":"Raju","year":"1997","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF372","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1080\/00039896.1974.10666472","article-title":"In vivo conversion of methylene chloride to carbon monoxide","volume":"28","author":"Ratney","year":"1974","journal-title":"Arch Environ Health"},{"key":"10.1124\/pr.57.4.3_REF373","first-page":"G799","article-title":"Inhibitory effect of CO on internal anal sphincter: heme oxygenase inhibitor inhibits NANC relaxation","volume":"265","author":"Rattan","year":"1993","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF374","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/S0006-291X(03)00856-8","article-title":"Heme oxygenase-1 fused to a TAT peptide transduces and protects pancreatic beta-cells","volume":"305","author":"Ribeiro","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF375","doi-asserted-by":"crossref","first-page":"C435","DOI":"10.1152\/ajpcell.1994.267.2.C435","article-title":"Carbon monoxide stimulates a potassium-selective current in rabbit corneal epithelial cells","volume":"267","author":"Rich","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF376","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1161\/hh1701.095632","article-title":"O2 modulates large-conductance Ca2+-dependent K+ channels of rat chemoreceptor cells by a membrane-restricted and CO-sensitive mechanism","volume":"89","author":"Riesco-Fagundo","year":"2001","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF377","first-page":"2","article-title":"Sources of carbon monoxide (CO) in biological systems and applications of CO detection technologies","volume":"18","author":"Rodgers","year":"1994","journal-title":"Semin Perinatol"},{"key":"10.1124\/pr.57.4.3_REF378","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1161\/01.HYP.0000085785.40581.1A","article-title":"Effects of exogenous heme on renal function: role of heme oxygenase and cyclooxygenase","volume":"42","author":"Rodriguez","year":"2003","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF379","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1152\/physrev.00021.2001","article-title":"P-450 metabolites of arachidonic acid in the control of cardiovascular function","volume":"82","author":"Roman","year":"2002","journal-title":"Physiol Rev"},{"key":"10.1124\/pr.57.4.3_REF380","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1152\/ajplegacy.1944.141.1.17","article-title":"The effect of carbon monoxide on the oxyhemoglobin dissociation curve","volume":"141","author":"Roughton","year":"1944","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF381","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1067\/msy.2001.111079","article-title":"Reduction of inflammatory response in composite flap transfer by local stress conditioning-induced heat-shock protein 32","volume":"129","author":"Rucker","year":"2001","journal-title":"Surgery"},{"key":"10.1124\/pr.57.4.3_REF382","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.biochem.71.090501.142857","article-title":"Metabolism and the control of circadian rhythms","volume":"71","author":"Rutter","year":"2002","journal-title":"Annu Rev Biochem"},{"key":"10.1124\/pr.57.4.3_REF383","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0891-5849(99)00223-3","article-title":"The heme synthesis and degradation pathways: role in oxidant sensitivity","volume":"28","author":"Ryter","year":"2000","journal-title":"Free Radic Biol Med"},{"key":"10.1124\/pr.57.4.3_REF384","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1161\/01.HYP.38.2.210","article-title":"Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats","volume":"38","author":"Sabaawy","year":"2001","journal-title":"Hypertension"},{"key":"10.1124\/pr.57.4.3_REF385","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1124\/jpet.103.057315","article-title":"Role of the Heme Oxygenases in Abnormalities of the mesenteric circulation in cirrhotic rats","volume":"308","author":"Sacerdoti","year":"2004","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/pr.57.4.3_REF386","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1126\/science.2492116","article-title":"Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats","volume":"243","author":"Sacerdoti","year":"1989","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF387","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1165\/rcmb.4816","article-title":"Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages","volume":"27","author":"Sarady","year":"2002","journal-title":"Am J Respir Cell Mol Biol"},{"key":"10.1124\/pr.57.4.3_REF388","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1159\/000137557","article-title":"The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals","volume":"23","author":"Sardana","year":"1981","journal-title":"Pharmacology"},{"key":"10.1124\/pr.57.4.3_REF389","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1002\/hep.20450","article-title":"Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury","volume":"40","author":"Sass","year":"2004","journal-title":"Hepatology"},{"key":"10.1124\/pr.57.4.3_REF390","first-page":"819","article-title":"Why heme needs to be degraded to iron, biliverdin IX\u03b1 and carbon monoxide?","volume":"6","author":"Sassa","year":"2004","journal-title":"Antioxid Redox Signal"},{"key":"10.1124\/pr.57.4.3_REF391","doi-asserted-by":"crossref","first-page":"4185","DOI":"10.4049\/jimmunol.166.6.4185","article-title":"Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants","volume":"166","author":"Sato","year":"2001","journal-title":"J Immunol"},{"key":"10.1124\/pr.57.4.3_REF392","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1432-1033.1990.tb15394.x","article-title":"Interaction of upstream stimulatory factor with the human heme oxygenase gene promoter","volume":"188","author":"Sato","year":"1990","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF393","doi-asserted-by":"crossref","first-page":"5133","DOI":"10.1021\/bi027067e","article-title":"Characterization of the heme environmental structure of cytoglobin, a fourth globin in humans","volume":"42","author":"Sawai","year":"2003","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF394","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0006-8993(02)03338-3","article-title":"Gene expression profiles of heme oxygenase isoforms in the rat brain","volume":"954","author":"Scapagnini","year":"2002","journal-title":"Brain Res"},{"key":"10.1124\/pr.57.4.3_REF395","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0026-895X(24)12118-9","article-title":"Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers","volume":"61","author":"Scapagnini","year":"2002","journal-title":"Mol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF396","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0076-6879(79)58173-7","article-title":"Adrenocortical Y1 cells","volume":"52","author":"Schimmer","year":"1979","journal-title":"Methods Enzymol"},{"key":"10.1124\/pr.57.4.3_REF397","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1212\/WNL.54.6.1297","article-title":"Evaluation of heme oxygenase-1 as a systemic biological marker of sporadic AD","volume":"54","author":"Schipper","year":"2000","journal-title":"Neurology"},{"key":"10.1124\/pr.57.4.3_REF398","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1006\/exnr.1997.6752","article-title":"Neural heme oxygenase-1 expression in idiopathic Parkinson\u2019s disease","volume":"150","author":"Schipper","year":"1998","journal-title":"Exp Neurol"},{"key":"10.1124\/pr.57.4.3_REF399","doi-asserted-by":"crossref","first-page":"623","DOI":"10.3109\/02713688709025223","article-title":"Cytochrome P450, drug metabolizing enzymes and arachidonic acid metabolism in bovine ocular tissues","volume":"6","author":"Schwartzman","year":"1987","journal-title":"Curr Eye Res"},{"key":"10.1124\/pr.57.4.3_REF400","doi-asserted-by":"crossref","first-page":"5177","DOI":"10.1074\/jbc.M008282200","article-title":"Mapping the pathways for O2 entry into and exit from myoglobin","volume":"276","author":"Scott","year":"2001","journal-title":"J Biol Chem"},{"issue":"Suppl 1","key":"10.1124\/pr.57.4.3_REF401","first-page":"62","article-title":"Pregnant woman with uterine contractions have lower end tidal carbon monoxide levels (Abstract 246)","volume":"103","author":"Seidman","year":"2000","journal-title":"Acta Hematologica"},{"key":"10.1124\/pr.57.4.3_REF402","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/ki.1997.77","article-title":"Structural and functional analysis of hypoxia-inducible factor 1","volume":"51","author":"Semenza","year":"1997","journal-title":"Kidney Int"},{"key":"10.1124\/pr.57.4.3_REF403","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0002-9149(03)00890-7","article-title":"Dysregulation of endogenous carbon monoxide and nitric oxide production in patients with advanced ischemic or nonischemic cardiomyopathy","volume":"92","author":"Seshadri","year":"2003","journal-title":"Am J Cardiol"},{"key":"10.1124\/pr.57.4.3_REF404","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1751-1097.1994.tb05065.x","article-title":"Visible light photochemical release of nitric oxide from S-nitrosoglutathione: potential photo-chemotherapeutic applications","volume":"59","author":"Sexton","year":"1994","journal-title":"J Photochem Photobiol"},{"key":"10.1124\/pr.57.4.3_REF405","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1006\/abbi.1999.1490","article-title":"Effects of phenylarsine oxide on expression of heme oxygenase-1 reporter constructs in transiently transfected cultures of chick embryo liver cells","volume":"372","author":"Shan","year":"1999","journal-title":"Arch Biochem Biophys"},{"key":"10.1124\/pr.57.4.3_REF406","first-page":"389","article-title":"Depletion of endogenous serotonin synthesis with p-CPA attenuates upregulation of constitutive isoform of heme oxygenase-2 expression, edema formation and cell injury following a focal trauma to the rat spinal cord","volume":"86","author":"Sharma","year":"2003","journal-title":"Acta Neurochir Suppl"},{"key":"10.1124\/pr.57.4.3_REF407","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0021-9258(18)55936-6","article-title":"The mechanism of porphyrin formation: the role of the tricarboxylic acid cycle","volume":"192","author":"Shemin","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF408","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1089\/15230860260220094","article-title":"Heme degradation and human disease: diversity is the soul of life","volume":"4","author":"Shibahara","year":"2002","journal-title":"Antioxid Redox Signal"},{"key":"10.1124\/pr.57.4.3_REF409","doi-asserted-by":"crossref","first-page":"12889","DOI":"10.1016\/S0021-9258(18)45138-1","article-title":"Transcriptional control of rat heme oxygenase by heat shock","volume":"262","author":"Shibahara","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF410","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1177\/15353702-0322805-08","article-title":"Repression of heme oxygenase-1 expression as a defense strategy in humans","volume":"228","author":"Shibahara","year":"2003","journal-title":"Exp Biol Med"},{"key":"10.1124\/pr.57.4.3_REF411","doi-asserted-by":"crossref","first-page":"17527","DOI":"10.1074\/jbc.M910376199","article-title":"Combined serum paraoxonase knockout\/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis","volume":"275","author":"Shih","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF412","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1097\/00003246-200003000-00033","article-title":"Protective effect of heme oxygenase induction in ischemic acute renal failure","volume":"28","author":"Shimizu","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1124\/pr.57.4.3_REF413","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/hep.510280202","article-title":"Carbon monoxide as a regulator of bile canalicular contractility in cultured rat hepatocytes","volume":"28","author":"Shinoda","year":"1998","journal-title":"Hepatology"},{"key":"10.1124\/pr.57.4.3_REF414","doi-asserted-by":"crossref","first-page":"F726","DOI":"10.1152\/ajprenal.2000.278.5.F726","article-title":"Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis","volume":"278","author":"Shiraishi","year":"2000","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/pr.57.4.3_REF415","series-title":"Catalytic Activation of Carbon Monoxide","first-page":"1","article-title":"Activation of carbon monoxide by carbon and oxygen coordination","author":"Shriver","year":"1981"},{"key":"10.1124\/pr.57.4.3_REF416","doi-asserted-by":"crossref","first-page":"F425","DOI":"10.1152\/ajprenal.00297.2003","article-title":"The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury","volume":"286","author":"Sikorski","year":"2004","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1124\/pr.57.4.3_REF417","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1748-1716.1951.tb00762.x","article-title":"Endogenous formation of carbon monoxide","volume":"22","author":"Sj\u00f6strand","year":"1950","journal-title":"Acta Physiol Scand"},{"key":"10.1124\/pr.57.4.3_REF418","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1748-1716.1952.tb00915.x","article-title":"The formation of carbon monoxide by the decomposition of haemoglobin in vivo","volume":"26","author":"Sj\u00f6strand","year":"1952","journal-title":"Acta Physiol Scand"},{"key":"10.1124\/pr.57.4.3_REF419","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-2760(91)90119-3","article-title":"Prostaglandin endoperoxide synthase: structure and catalysis","volume":"1083","author":"Smith","year":"1991","journal-title":"Biochem Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF420","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0165-0173(97)00032-5","article-title":"Nitric oxide and carbon monoxide: parallel roles as neural messengers","volume":"26","author":"Snyder","year":"1998","journal-title":"Brain Res Rev"},{"key":"10.1124\/pr.57.4.3_REF421","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1038\/2063","article-title":"Expression of heme oxygenase-1 can determine cardiac xenograft survival","volume":"4","author":"Soares","year":"1998","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF422","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/jpsu.2003.50172","article-title":"Expression of heme oxygenase-1 and endothelial nitric oxide synthase in the lung of newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension","volume":"38","author":"Solari","year":"2003","journal-title":"J Pediatr Surg"},{"key":"10.1124\/pr.57.4.3_REF423","doi-asserted-by":"crossref","first-page":"44327","DOI":"10.1074\/jbc.M406105200","article-title":"Carbon monoxide promotes Fas\/CD95-induced apoptosis in Jurkat cells","volume":"279","author":"Song","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF424","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/1357-2725(96)00030-1","article-title":"Mitochondrial heme oxygenase of Mastomys coucha","volume":"28","author":"Srivastava","year":"1996","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1124\/pr.57.4.3_REF425","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/364147a0","article-title":"Reversal of long-term potentiation by inhibitors of haem oxygenase","volume":"364","author":"Stevens","year":"1993","journal-title":"Nature (Lond)"},{"key":"10.1124\/pr.57.4.3_REF426","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1093\/clinchem\/40.10.1934","article-title":"Bilirubin production in healthy term infants as measured by carbon monoxide in breath","volume":"40","author":"Stevenson","year":"1994","journal-title":"Clin Chem"},{"key":"10.1124\/pr.57.4.3_REF427","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1146\/annurev.pa.15.040175.002205","article-title":"The effect of carbon monoxide on humans","volume":"17","author":"Stewart","year":"1975","journal-title":"Annu Rev Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF428","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1126\/science.176.4032.295","article-title":"Carboxyhemoglobin elevation after exposure to dichloromethane","volume":"176","author":"Stewart","year":"1972","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF429","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1126\/science.3029864","article-title":"Bilirubin is an antioxidant of possible physiological importance","volume":"235","author":"Stocker","year":"1987","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF430","doi-asserted-by":"crossref","first-page":"5636","DOI":"10.1021\/bi00184a036","article-title":"Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states","volume":"33","author":"Stone","year":"1994","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF431","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1749-6632.1970.tb49799.x","article-title":"Physiological and biochemical effects on rats and mice exposed to small concentrations of carbon monoxide for long periods","volume":"174","author":"Stupfel","year":"1970","journal-title":"Ann NY Acad Sci"},{"key":"10.1124\/pr.57.4.3_REF432","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1172\/JCI118300","article-title":"Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver","volume":"96","author":"Suematsu","year":"1995","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF433","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1006\/bbrc.1994.2811","article-title":"CO as an endogenous modulator of vascular perfusion","volume":"205","author":"Suematsu","year":"1994","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF434","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1161\/01.RES.83.11.1069","article-title":"Nitric oxide-20-hydroxyeicosatetraenoic acid interaction in the regulation of K+ channel activity and vascular tone in renal arterioles","volume":"83","author":"Sun","year":"1998","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF435","doi-asserted-by":"crossref","first-page":"5216","DOI":"10.1093\/emboj\/cdf516","article-title":"Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene","volume":"21","author":"Sun","year":"2002","journal-title":"EMBO (Eur Mol Biol Organ) J"},{"key":"10.1124\/pr.57.4.3_REF436","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1096\/fasebj.13.13.1800","article-title":"Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron","volume":"13","author":"Suttner","year":"1999","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF437","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1161\/01.RES.43.3.429","article-title":"The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vasoconstriction","volume":"43","author":"Sylvester","year":"1978","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF438","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/carcin\/22.9.1363","article-title":"Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells","volume":"22","author":"Tacchini","year":"2001","journal-title":"Carcinogenesis"},{"key":"10.1124\/pr.57.4.3_REF439","doi-asserted-by":"crossref","first-page":"28681","DOI":"10.1074\/jbc.M310661200","article-title":"Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability","volume":"279","author":"Taille","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF440","doi-asserted-by":"crossref","first-page":"5395","DOI":"10.1074\/jbc.275.8.5395","article-title":"Overexpression of heme oxygenase in neuronal cells, the possible interaction with tau","volume":"275","author":"Takeda","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF441","doi-asserted-by":"crossref","first-page":"22858","DOI":"10.1016\/S0021-9258(17)31724-6","article-title":"Identification of a cis-acting element that is responsible for cadmium-mediatedinduction of the human heme oxygenase gene","volume":"269","author":"Takeda","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF442","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1046\/j.1471-4159.1999.0722356.x","article-title":"Suppression of heme oxygenase-1 mRNA expression by interferon-gamma in human glioblastoma cells","volume":"72","author":"Takahashi","year":"1999","journal-title":"J Neurochem"},{"key":"10.1124\/pr.57.4.3_REF443","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0896-6273(00)00125-2","article-title":"Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer\u2019s disease","volume":"28","author":"Takahashi","year":"2000","journal-title":"Neuron"},{"key":"10.1124\/pr.57.4.3_REF444","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1042\/bj20020819","article-title":"Cooperation of the transcription factor hepatocyte nuclear factor-4 with Sp1 or Sp3 leads to transcriptional activation of the human haem oxygenase-1 gene promoter in a hepatoma cell line","volume":"367","author":"Takahashi","year":"2002","journal-title":"Biochem J"},{"key":"10.1124\/pr.57.4.3_REF445","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0167-4781(99)00156-6","article-title":"Positive and negative regulation of the human heme oxygenase-1 gene expression in cultured cells","volume":"1447","author":"Takahashi","year":"1999","journal-title":"Biochim Biophys Acta"},{"key":"10.1124\/pr.57.4.3_REF446","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1034\/j.1600-079X.2003.02111.x","article-title":"Melatonin: a hormone, a tissue factor, an autocoid, a paracoid and an antioxidant vitamin","volume":"34","author":"Tan","year":"2003","journal-title":"J Pineal Res"},{"key":"10.1124\/pr.57.4.3_REF447","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/nature02003","article-title":"Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels","volume":"425","author":"Tang","year":"2003","journal-title":"Nature (Lond)"},{"key":"10.1124\/pr.57.4.3_REF448","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1073\/pnas.61.2.748","article-title":"The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase","volume":"61","author":"Tenhunen","year":"1968","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF449","doi-asserted-by":"crossref","first-page":"6388","DOI":"10.1016\/S0021-9258(18)63477-5","article-title":"Microsomal heme oxygenase. Characterization of the enzyme","volume":"244","author":"Tenhunen","year":"1969","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF450","first-page":"410","article-title":"The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin","volume":"75","author":"Tenhunen","year":"1970","journal-title":"J Lab Clin Med"},{"key":"10.1124\/pr.57.4.3_REF451","first-page":"H1207","article-title":"Hypoxic contraction of small pulmonary arteries from normal and endotoxemic rats: fundamental role of NO","volume":"276","author":"Terraz","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF452","first-page":"H1493","article-title":"TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+ and phospholipase A2 in endothelial cells","volume":"276","author":"Terry","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF453","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1038\/87853","article-title":"Inhaled CO: deadly gas or novel therapeutic?","volume":"7","author":"Thiemermann","year":"2001","journal-title":"Nat Med"},{"key":"10.1124\/pr.57.4.3_REF454","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1152\/jappl.1990.68.3.997","article-title":"Carbon monoxide mediated brain lipid peroxidation in the rat","volume":"68","author":"Thom","year":"1990","journal-title":"J Appl Physiol"},{"key":"10.1124\/pr.57.4.3_REF455","first-page":"H984","article-title":"Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat","volume":"276","author":"Thom","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF456","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1073\/pnas.97.3.1305","article-title":"Adaptive responses and apoptosis in endothelial cells exposed to carbon monoxide","volume":"97","author":"Thom","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF457","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/taap.1998.8553","article-title":"Pulmonary vascular stress from carbon monoxide","volume":"154","author":"Thom","year":"1999","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF458","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1021\/tx970041h","article-title":"Vascular endothelial cells generate peroxynitrite in response to carbon monoxide exposure","volume":"10","author":"Thom","year":"1997","journal-title":"Chem Res Toxicol"},{"key":"10.1124\/pr.57.4.3_REF459","first-page":"F882","article-title":"Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS","volume":"277","author":"Thorup","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF460","doi-asserted-by":"crossref","first-page":"H623","DOI":"10.1152\/ajpheart.2000.278.2.H623","article-title":"Protective roles of endogenous carbon monoxide in neointimal development elicited by arterial injury","volume":"278","author":"Togane","year":"2000","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF461","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.cardiores.2004.04.015","article-title":"Heme oxygenase-1 inhibition of MAP kinases, calcineurin\/NFAT signaling and hypertrophy in cardiac myocytes","volume":"63","author":"Tongers","year":"2004","journal-title":"Cardiovasc Res"},{"key":"10.1124\/pr.57.4.3_REF462","doi-asserted-by":"crossref","first-page":"11131","DOI":"10.1016\/S0021-9258(18)67358-2","article-title":"Purification and characterization of the major constitutive form of testicular heme oxygenase: the non-inducible isoform","volume":"261","author":"Trakshel","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF463","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0006-291X(88)90682-1","article-title":"Detection of two heme oxygenase isoforms in the human testis","volume":"154","author":"Trakshel","year":"1988","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF464","doi-asserted-by":"crossref","first-page":"3833","DOI":"10.1210\/jcem.86.8.7715","article-title":"Estrogen increases endothelial carbon monoxide, heme oxygenase 2 and carbon monoxide-derived cGMP by a receptor-mediated system","volume":"86","author":"Tschugguel","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1124\/pr.57.4.3_REF465","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1089\/10430340260355356","article-title":"Adenovirus-mediated transfer and overexpression of heme oxygenase 1 cDNA in lung prevents bleomycin-induced pulmonary fibrosis via a Fas-Fas ligand-independent pathway","volume":"13","author":"Tsuburai","year":"2002","journal-title":"Hum Gene Ther"},{"key":"10.1124\/pr.57.4.3_REF466","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/00007890-200209150-00001","article-title":"Inhibition of ischemia\/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1","volume":"74","author":"Tullius","year":"2002","journal-title":"Transplantation"},{"key":"10.1124\/pr.57.4.3_REF467","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1023\/A:1007416505088","article-title":"Carbon monoxide induces murine thymocyte apoptosis by a free radical-mediated mechanism","volume":"14","author":"Turcanu","year":"1998","journal-title":"Cell Biol Toxicol"},{"key":"10.1124\/pr.57.4.3_REF468","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0923-2494(99)80050-9","article-title":"Nitric oxide synthase inhibition by haem oxygenase decreases macrophage nitric-oxide-dependent cytotoxicity: a negative feedback mechanism for the regulation of nitric oxide production","volume":"149","author":"Turcanu","year":"1998","journal-title":"Res Immunol"},{"key":"10.1124\/pr.57.4.3_REF469","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1046\/j.1365-2826.1998.00266.x","article-title":"Influence of carbon monoxide and its interaction with nitric oxide, on the adrenocorticotropin hormone response of the normal rat to a physico-emotional stress","volume":"10","author":"Turnbull","year":"1998","journal-title":"J Neuroendocrinol"},{"key":"10.1124\/pr.57.4.3_REF470","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1080\/10715769900300901","article-title":"Redox regulation and oxidant activation of heme oxygenase-1","volume":"31","author":"Tyrrell","year":"1999","journal-title":"Free Radic Res"},{"key":"10.1124\/pr.57.4.3_REF471","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/carcin\/14.4.761","article-title":"The proximal promoter region of the human heme oxygenase gene contains elements involved in stimulation of transcriptional activity by a variety of agents including oxidants","volume":"14","author":"Tyrrell","year":"1993","journal-title":"Carcinogenesis"},{"key":"10.1124\/pr.57.4.3_REF472","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1016\/S0021-9258(18)97372-2","article-title":"Studies on the electron transfer system: LXII. The reaction of cytochrome oxidase with carbon monoxide","volume":"240","author":"Tzagoloff","year":"1965","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF473","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0039-6060(97)90016-7","article-title":"Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis","volume":"122","author":"Tzeng","year":"1997","journal-title":"Surgery"},{"key":"10.1124\/pr.57.4.3_REF474","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1111\/j.1432-1033.2004.04241.x","article-title":"Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells","volume":"271","author":"Udono-Fujimori","year":"2004","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF475","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1248\/bpb.18.529","article-title":"Formation of carbon monoxide during mouse hepatic microsomal oxidative metabolism of cannabidiol; identification and determination","volume":"18","author":"Usami","year":"1995","journal-title":"Biol Pharm Bull"},{"key":"10.1124\/pr.57.4.3_REF476","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1291\/hypres.27.253","article-title":"Erectile dysfunction in hypertensive rats results from impairment of the relaxation evoked by neurogenic carbon monoxide and nitric oxide","volume":"27","author":"Ushiyama","year":"2004","journal-title":"Hypertens Res"},{"key":"10.1124\/pr.57.4.3_REF477","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/0006-2952(91)90658-R","article-title":"Carbon monoxide relaxes ileal smooth muscle through activation of guanylyl cyclase","volume":"41","author":"Utz","year":"1991","journal-title":"Biochem Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF478","first-page":"601","article-title":"Similar endothelium-independent arterial relaxation by carbon monoxide and nitric oxide","volume":"48","author":"Vedernikov","year":"1989","journal-title":"Biomed Biochim Acta"},{"key":"10.1124\/pr.57.4.3_REF479","first-page":"1497","article-title":"Vascular smooth muscle contains a depletable store of a vasodilator which is light activated and restored by donors of nitric oxide","volume":"266","author":"Venturini","year":"1993","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1124\/pr.57.4.3_REF480","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1126\/science.7678352","article-title":"Carbon monoxide: a putative neural messenger","volume":"259","author":"Verma","year":"1993","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF481","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1046\/j.1432-1327.1999.00843.x","article-title":"Tissue variant effects of heme inhibitors on the mouse cytochrome c oxidase gene expression and catalytic activity of the enzyme complex","volume":"266","author":"Vijayasarathy","year":"1999","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF482","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1203\/00006450-200010000-00021","article-title":"Relaxant effects of carbon monoxide compared with nitric oxide in pulmonary and systemic vessels of newborn piglets","volume":"48","author":"Villamor","year":"2000","journal-title":"Pediatr Res"},{"key":"10.1124\/pr.57.4.3_REF483","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/0003-9861(88)90159-2","article-title":"The influence of heme-binding proteins in heme-catalyzed oxidations","volume":"265","author":"Vincent","year":"1988","journal-title":"Arch Biochem Biophys"},{"key":"10.1124\/pr.57.4.3_REF484","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0306-4522(94)90018-3","article-title":"Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons","volume":"63","author":"Vincent","year":"1994","journal-title":"Neuroscience"},{"key":"10.1124\/pr.57.4.3_REF485","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S1011-1344(00)00148-2","article-title":"NO-hemoglobin may be a light-sensitive source of nitric oxide both in solution and in red blood cells","volume":"59","author":"Vladimirov","year":"2000","journal-title":"J Photochem Photobiol B"},{"key":"10.1124\/pr.57.4.3_REF486","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1172\/JCI119020","article-title":"Glomerular inflammation induces resistance to tubular injury in the rat: a novel form of acquired, heme oxygenase-dependent resistance to renal injury","volume":"98","author":"Vogt","year":"1996","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF487","first-page":"928","article-title":"Dark adaptation of the eye during carbon monoxide exposure in smokers and nonsmokers","volume":"59","author":"von Restorff","year":"1988","journal-title":"Aviat Space Environ Med"},{"key":"10.1124\/pr.57.4.3_REF488","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/S0016-5085(84)80072-4","article-title":"Increased blood flow through the portal system in cirrhotic rats","volume":"87","author":"Vorobioff","year":"1984","journal-title":"Gastroenterology"},{"key":"10.1124\/pr.57.4.3_REF489","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1203\/00006450-199302000-00021","article-title":"Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivity","volume":"33","author":"Vreman","year":"1993","journal-title":"Pediatr Res"},{"key":"10.1124\/pr.57.4.3_REF490","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1053\/plac.1999.0495","article-title":"Heme oxygenase activity in human umbilical cord and rat vascular tissues","volume":"21","author":"Vreman","year":"1999","journal-title":"Placenta"},{"key":"10.1124\/pr.57.4.3_REF491","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1139\/y98-126","article-title":"Simultaneous production of carbon monoxide and thiobarbituric acid reactive substances in rat tissue preparations by an iron ascorbate system","volume":"76","author":"Vreman","year":"1998","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF492","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1124\/pr.55.3.5","article-title":"Different faces of the heme-heme oxygenase system in inflammation","volume":"55","author":"Wagener","year":"2003","journal-title":"Pharmacol Rev"},{"key":"10.1124\/pr.57.4.3_REF493","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1172\/JCI119569","article-title":"Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells","volume":"100","author":"Wagner","year":"1997","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF494","first-page":"37","article-title":"Vasorelaxation induced by carbon monoxide and underlying mechanisms","volume":"27","author":"Wang","year":"1996","journal-title":"Physiol Can"},{"key":"10.1124\/pr.57.4.3_REF495","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1139\/y97-187","article-title":"Resurgence of carbon monoxide: an endogenous gaseous vasorelaxing factor","volume":"76","author":"Wang","year":"1998","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF496","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1096\/fj.02-0211hyp","article-title":"Two\u2019s company, three\u2019s a crowd: Can H2S be the third endogenous gaseous transmitter?","volume":"16","author":"Wang","year":"2002","journal-title":"FASEB J"},{"key":"10.1124\/pr.57.4.3_REF497","series-title":"Signal Transduction and the Gasotransmitters: NO, CO and H2S in Biology and Medicine","first-page":"3","article-title":"Chapter 1: The evolvement of gasotransmitter biology and medicine: from atmospheric toxic gases to endogenous gaseous signaling molecules","author":"Wang","year":"2004"},{"key":"10.1124\/pr.57.4.3_REF498","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/sj.bjp.0701222","article-title":"Carbon monoxide-induced vasorelaxation and the underlying mechanisms","volume":"121","author":"Wang","year":"1997","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF498a","doi-asserted-by":"crossref","first-page":"166","DOI":"10.2337\/diabetes.50.1.166","article-title":"Reduced vasorelaxant effect of carbon monoxide in diabetes and the underlying mechanisms","volume":"50","author":"Wang","year":"2001","journal-title":"Diabetes"},{"key":"10.1124\/pr.57.4.3_REF500","doi-asserted-by":"crossref","first-page":"8222","DOI":"10.1074\/jbc.272.13.8222","article-title":"The chemical modification of KCa channels by carbon monoxide in vascular smooth muscle cells","volume":"272","author":"Wang","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1124\/pr.57.4.3_REF501","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1177\/15353702-0322805-09","article-title":"Interaction of selective amino acid residues of KCa channels with carbon monoxide","volume":"228","author":"Wang","year":"2003","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1124\/pr.57.4.3_REF502","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s004240050398","article-title":"The direct effect of carbon monoxide on KCa channels in vascular smooth muscle cells","volume":"434","author":"Wang","year":"1997","journal-title":"Pflueg Arch Eur J Physiol"},{"key":"10.1124\/pr.57.4.3_REF503","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1179\/135100001101536580","article-title":"Haptoglobin, an inflammation-inducible plasma protein","volume":"6","author":"Wang","year":"2001","journal-title":"Redox Rep"},{"key":"10.1124\/pr.57.4.3_REF503a","first-page":"341","article-title":"The enzyme problem and biological oxidations","volume":"46","author":"Warburg","year":"1930","journal-title":"Johns Hopkins Bull"},{"key":"10.1124\/pr.57.4.3_REF505","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1073\/pnas.0308695100","article-title":"Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic\/noncholinergic neurotransmission","volume":"101","author":"Watkins","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF506","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1353\/pbm.1965.0052","article-title":"Reminiscences of Hans Fischer and his laboratory","volume":"8","author":"Watson","year":"1965","journal-title":"Perspect Biol Med"},{"key":"10.1124\/pr.57.4.3_REF507","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1046\/j.1471-4159.1994.63030953.x","article-title":"Corticosterone regulates heme oxygenase-2 and NO synthase transcription and protein expression in rat brain","volume":"63","author":"Weber","year":"1994","journal-title":"J Neurochem"},{"key":"10.1124\/pr.57.4.3_REF508","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/sj.bjp.0700893","article-title":"Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and lower oesophagogastric junction","volume":"120","author":"Werkstrom","year":"1997","journal-title":"Br J Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF509","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1146\/annurev.bi.49.070180.001531","article-title":"Oxygen activation by cytochrome P450","volume":"49","author":"White","year":"1980","journal-title":"Annu Rev Biochem"},{"key":"10.1124\/pr.57.4.3_REF510","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1161\/hh1001.091521","article-title":"Exacerbation of chronic renovascular hypertension and acute renal failure in heme oxygenase-1-deficient mice","volume":"88","author":"Wiesel","year":"2001","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF511","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1126\/science.1105010","article-title":"Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel","volume":"306","author":"Williams","year":"2004","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF512","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1006\/bbrc.1995.2406","article-title":"Modulation of heme oxygenase activity in rat brain and spleen by inhibitors and donors of nitric oxide","volume":"214","author":"Willis","year":"1995","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF513","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1006\/taap.1996.8077","article-title":"Effect of long-term ethanol pretreatment on the metabolism of dichloromethane to carbon monoxide in rats","volume":"143","author":"Wirkner","year":"1997","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF514","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1021\/bi00783a001","article-title":"Carbon monoxide binding studies of cytochrome a,a3 hemes in intact rat liver mitochondria","volume":"10","author":"Wohlrab","year":"1971","journal-title":"Biochemistry"},{"key":"10.1124\/pr.57.4.3_REF515","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/0006-291X(76)90199-6","article-title":"The formation of carbon monoxide during peroxidation of microsomal lipids","volume":"73","author":"Wolff","year":"1976","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF516","doi-asserted-by":"crossref","first-page":"G1172","DOI":"10.1152\/ajpgi.2001.280.6.G1172","article-title":"Characterization of a human plasma membrane heme transporter in intestinal and hepatocyte cell lines","volume":"280","author":"Worthington","year":"2001","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1124\/pr.57.4.3_REF517","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1139\/y04-112","article-title":"The pro-oxidant role of methylglyoxal in mesenteric artery smooth muscle cells","volume":"83","author":"Wu","year":"2005","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1124\/pr.57.4.3_REF518","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1172\/JCI0215316","article-title":"Different mechanisms underlying the stimulation of KCa channels by nitric oxide and carbon monoxide","volume":"110","author":"Wu","year":"2002","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF519","doi-asserted-by":"crossref","first-page":"H610","DOI":"10.1152\/ajpheart.00782.2003","article-title":"Carbon monoxide activates KCa channels in newborn arteriole smooth muscle cells by increasing apparent Ca2+ sensitivity of alpha-subunits","volume":"286","author":"Xi","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF520","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1073\/pnas.97.4.1851","article-title":"Carbon monoxide and nitric oxide as coneurotransmitters in the enteric nervous system: evidence from genomic deletion of biosynthetic enzymes","volume":"97","author":"Xue","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF521","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1172\/JCI4165","article-title":"Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency","volume":"103","author":"Yachie","year":"1999","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF522","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1177\/15353702-0322805-26","article-title":"Heme oxygenase-1 production by peripheral blood monocytes during acute inflammatory illnesses of children","volume":"228","author":"Yachie","year":"2003","journal-title":"Exp Biol Med"},{"key":"10.1124\/pr.57.4.3_REF523","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1086\/302729","article-title":"Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema","volume":"66","author":"Yamada","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1124\/pr.57.4.3_REF524","first-page":"L127","article-title":"Retrovirus-mediated HO gene transfer into endothelial cells protects against oxidant-induced injury","volume":"277","author":"Yang","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1124\/pr.57.4.3_REF525","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.bbrc.2004.01.061","article-title":"Interaction between endogenous nitric oxide and carbon monoxide in the pathogenesis of recurrent febrile seizures","volume":"315","author":"Yang","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1124\/pr.57.4.3_REF526","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1210\/endo.139.10.6244","article-title":"A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1\u03b2","volume":"139","author":"Ye","year":"1998","journal-title":"Endocrinology"},{"key":"10.1124\/pr.57.4.3_REF527","doi-asserted-by":"crossref","first-page":"R23","DOI":"10.1172\/JCI6163","article-title":"Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice","volume":"103","author":"Yet","year":"1999","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF528","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1161\/hh1401.093314","article-title":"Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice","volume":"89","author":"Yet","year":"2001","journal-title":"Circ Res"},{"key":"10.1124\/pr.57.4.3_REF529","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0169-328X(02)00586-7","article-title":"Oxidative stress regulated genes in nigral dopaminergic neuronal cells: correlation with the known pathology in Parkinson\u2019s disease","volume":"110","author":"Yoo","year":"2003","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1124\/pr.57.4.3_REF530","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1432-1033.1988.tb13811.x","article-title":"Human heme oxygenase cDNA and induction of its mRNA by hemin","volume":"171","author":"Yoshida","year":"1988","journal-title":"Eur J Biochem"},{"key":"10.1124\/pr.57.4.3_REF531","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1161\/01.CIR.103.12.1695","article-title":"H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: a study with transgenic mice heterozygous for targeted disruption of the heme oxygenase-1 gene","volume":"103","author":"Yoshida","year":"2001","journal-title":"Circulation"},{"key":"10.1124\/pr.57.4.3_REF532","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1093\/oxfordjournals.jbchem.a130494","article-title":"Partial purification and reconstruction of the heme oxygenase system from pig spleen microsomes","volume":"75","author":"Yoshida","year":"1974","journal-title":"J Biochem (Tokyo)"},{"key":"10.1124\/pr.57.4.3_REF533","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1042\/bj2390225","article-title":"Mitochondrial oxygenation of carbon monoxide","volume":"239","author":"Young","year":"1986","journal-title":"Biochem J"},{"key":"10.1124\/pr.57.4.3_REF534","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0014-5793(90)80436-M","article-title":"Pathobiochemistry of CO poisoning","volume":"272","author":"Young","year":"1990","journal-title":"FEBS Lett"},{"key":"10.1124\/pr.57.4.3_REF535","series-title":"Biochemical and Clinical Aspects of Oxygen: Proceedings of a Symposium (September 1975, Fort Collins, CO)","first-page":"355","article-title":"Role of oxygen and cytochrome c oxidase in the detoxification of CO by oxidation to CO2","author":"Young","year":"1979"},{"key":"10.1124\/pr.57.4.3_REF536","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1073\/pnas.91.5.1691","article-title":"Nitric oxide: a mediator in rat tubular hypoxia\/reoxygenation injury","volume":"91","author":"Yu","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF537","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1073\/pnas.93.2.795","article-title":"Heme oxygenase 2: endothelial and neuronal localization and role in endothelium-dependent relaxation","volume":"93","author":"Zakhary","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF538","doi-asserted-by":"crossref","first-page":"14848","DOI":"10.1073\/pnas.94.26.14848","article-title":"Targeted gene deletion of heme oxygenase 2 reveals neural role for carbon monoxide","volume":"94","author":"Zakhary","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1124\/pr.57.4.3_REF539","doi-asserted-by":"crossref","first-page":"H350","DOI":"10.1152\/ajpheart.2001.281.1.H350","article-title":"Carbon monoxide produced by isolated arterioles attenuates pressure-induced vasoconstriction","volume":"281","author":"Zhang","year":"2001","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1124\/pr.57.4.3_REF540","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1172\/JCI115980","article-title":"Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain","volume":"90","author":"Zhang","year":"1992","journal-title":"J Clin Investig"},{"key":"10.1124\/pr.57.4.3_REF541","first-page":"356","article-title":"The role of endogenous carbon monoxide in the hypoxic vascular remodeling of rat model of hypoxic pulmonary hypertension","volume":"23","author":"Zhen","year":"2003","journal-title":"J Huazhong Univ Sci Technolog Med Sci"},{"key":"10.1124\/pr.57.4.3_REF542","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1126\/science.8100368","article-title":"Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus","volume":"260","author":"Zhuo","year":"1993","journal-title":"Science (Wash DC)"},{"key":"10.1124\/pr.57.4.3_REF543","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1084\/jem.20031003","article-title":"Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1","volume":"198","author":"Zuckerbraun","year":"2003","journal-title":"J Exp Med"},{"key":"10.1124\/pr.57.4.3_REF544","doi-asserted-by":"crossref","first-page":"G607","DOI":"10.1152\/ajpgi.00055.2005","article-title":"Carbon monoxide protects against the development of experimental necrotizing enterocolitis","volume":"289","author":"Zuckerbraun","year":"2005","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1124\/pr.57.4.3_REF545","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.1523\/JNEUROSCI.17-08-02703.1997","article-title":"Identification of a long-lasting form of odor adaptation that depends on the carbon monoxide\/cGMP second-messenger system","volume":"17","author":"Zufall","year":"1997","journal-title":"J Neurosci"},{"key":"10.1124\/pr.57.4.3_REF546","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1748-1716.1994.tb09793.x","article-title":"Light-dependent effects of zinc protoporphyrin IX on endothelium-dependent relaxation resistant to N omega-nitro-l-arginine","volume":"152","author":"Zygmunt","year":"1994","journal-title":"Acta Physiol Scand"}],"container-title":["Pharmacological Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031699724116274?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0031699724116274?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1124\/pr.57.4.3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T08:33:34Z","timestamp":1737275614000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0031699724116274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":546,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0031699724116274"],"URL":"https:\/\/doi.org\/10.1124\/pr.57.4.3","relation":{},"ISSN":["0031-6997"],"issn-type":[{"value":"0031-6997","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications","name":"articletitle","label":"Article Title"},{"value":"Pharmacological Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1124\/pr.57.4.3","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 American Society for Pharmacology and Experimental Therapeutics. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}