{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T04:13:57Z","timestamp":1774584837703,"version":"3.50.1"},"reference-count":22,"publisher":"American Association for the Advancement of Science (AAAS)","issue":"5984","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Science"],"published-print":{"date-parts":[[2010,6,11]]},"abstract":"<jats:title>The Inner Life<\/jats:title>\n                  <jats:p>\n                    The influence of intestinal flora on the physiology of the entire host organism has only recently begun to be appreciated. The mammalian gut is not just home to billions of bacteria and archaea, but often harbors much larger creatures such as protozoa, nematodes, and tapeworms. Anticipating a web of interactions among these organisms,\n                    <jats:bold>\n                      Hayes\n                      <jats:italic>et al.<\/jats:italic>\n                    <\/jats:bold>\n                    (p.\n                    <jats:related-article xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"doi\" page=\"1391\" related-article-type=\"in-this-issue\" vol=\"328\" xlink:href=\"10.1126\/science.1187703\">1391<\/jats:related-article>\n                    ) investigated the relationship between a common nematode parasite of mice,\n                    <jats:italic>Trichuris muris<\/jats:italic>\n                    , and its dependency on the occurrence of enterobacteria, such as\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Salmonella typhimurium<\/jats:italic>\n                    . The worms were found to be dependent on the presence of bacteria for hatching, and hatching was triggered by the presence of bacterial surface structures called fimbriae, which bind to proteins at the poles of the worms' eggs.\n                  <\/jats:p>","DOI":"10.1126\/science.1187703","type":"journal-article","created":{"date-parts":[[2010,6,10]],"date-time":"2010-06-10T15:20:35Z","timestamp":1276183235000},"page":"1391-1394","source":"Crossref","is-referenced-by-count":293,"title":["Exploitation of the Intestinal Microflora by the Parasitic Nematode\n                    <i>Trichuris muris<\/i>"],"prefix":"10.1126","volume":"328","author":[{"given":"K. S.","family":"Hayes","sequence":"first","affiliation":[{"name":"Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK."}]},{"given":"A. J.","family":"Bancroft","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK."}]},{"given":"M.","family":"Goldrick","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK."}]},{"given":"C.","family":"Portsmouth","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK."}]},{"given":"I. S.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK."}]},{"given":"R. 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